Citation Impact
Citing Papers
NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations
2008
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans
2012 StandoutNobel
Combinatorial Treatments That Overcome PDGFRβ-Driven Resistance of Melanoma Cells to V600EB-RAF Inhibition
2011
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Effects of the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 on the Tumor Vasculature: Implications for Clinical Imaging
2008
Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin
2009
Phosphatidylinositol 3-Kinase Hyperactivation Results in Lapatinib Resistance that Is Reversed by the mTOR/Phosphatidylinositol 3-Kinase Inhibitor NVP-BEZ235
2008
ER Tubules Mark Sites of Mitochondrial Division
2011 StandoutScience
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
2010 StandoutScience
Introduction of the MASH1 gene into mouse embryonic stem cells leads to differentiation of motoneuron precursors lacking Nogo receptor expression that can be applicable for transplantation to spinal cord injury
2006
Hallmarks of Cancer: The Next Generation
2011 Standout
SCHEMA Recombination of a Fungal Cellulase Uncovers a Single Mutation That Contributes Markedly to Stability
2009 StandoutNobel
Triple-Negative Breast Cancer
2010 Standout
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
A Class of Membrane Proteins Shaping the Tubular Endoplasmic Reticulum
2006
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
2009
Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency 1 1Edited by J. A. Wells
1999
mTOR Signaling in Growth Control and Disease
2012 Standout
Bex1 is involved in the regeneration of axons after injury
2010
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
2008 StandoutNature
Drug discovery approaches targeting the PI3K/Akt pathway in cancer
2008
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
2009 Standout
Cell-type Specific Targeting of the α2c-Adrenoceptor
2000 StandoutNobel
Kinetic Analysis of the Mechanism and Specificity of Protein-disulfide Isomerase Using Fluorescence-quenched Peptides
1998 StandoutNobel
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Sensitizing Anthrax Lethal Toxin-resistant Macrophages to Lethal Toxin-induced Killing by Tumor Necrosis Factor-α
2003 StandoutNobel
Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles
1997 StandoutNobel
Dynamics of mitochondrial morphology in healthy cells and during apoptosis
2003
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Different degradation pathways for heterologous glycoproteins in yeast
1998
TORC2 Signaling Pathway Guarantees Genome Stability in the Face of DNA Strand Breaks
2013
BrafV600E cooperates with Pten loss to induce metastatic melanoma
2009
Ald6p Is a Preferred Target for Autophagy in Yeast, Saccharomyces cerevisiae
2004 StandoutNobel
The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions
2002
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor
2010
Competition between glutathione and protein thiols for disulphide-bond formation
1999
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
2007
Does COPI Go Both Ways?
1997 StandoutNobel
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
2002 Standout
A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation
2001
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Network organization of the human autophagy system
2010 StandoutNature
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
In Vitro Selection and Characterization of Bcl-XL-binding Proteins from a Mix of Tissue-specific mRNA Display Libraries
2001
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
Potent Glycan Inhibitors of Myelin-associated Glycoprotein Enhance Axon Outgrowth in Vitro
2005
Ero1p: A Novel and Ubiquitous Protein with an Essential Role in Oxidative Protein Folding in the Endoplasmic Reticulum
1998
TANGO1 Facilitates Cargo Loading at Endoplasmic Reticulum Exit Sites
2009 StandoutNobel
Autophagy in the Pathogenesis of Disease
2008 Standout
Mitochondrial dynamics and apoptosis
2008
The molecular mechanism and cellular functions of mitochondrial division
2008
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Methods in Mammalian Autophagy Research
2010 Standout
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
Ero1p Oxidizes Protein Disulfide Isomerase in a Pathway for Disulfide Bond Formation in the Endoplasmic Reticulum
1999
Targeting the PI3K–AKT–mTOR pathway: progress, pitfalls, and promises
2008
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
Transgenic inhibition of Nogo-66 receptor function allows axonal sprouting and improved locomotion after spinal injury
2005
Autophagy Is Required for Maintenance of Amino Acid Levels and Protein Synthesis under Nitrogen Starvation
2005 StandoutNobel
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
Spinal Cord Injury: Time to Move?
2007
ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells
2007
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases
2008
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
2009 Standout
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
2010
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Investigating Mitochondrial Redox Potential with Redox-sensitive Green Fluorescent Protein Indicators
2004 StandoutNobel
The ERO1 Gene of Yeast Is Required for Oxidation of Protein Dithiols in the Endoplasmic Reticulum
1998
Frequent Activating Mutations of PIK3CA in Ovarian Clear Cell Carcinoma
2009
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans
2009
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae
2000 StandoutNobel
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
THE CENTRAL EFFECTORS OF CELL DEATH IN THE IMMUNE SYSTEM
1999
Pushing the Envelope in the mTOR Pathway: The Second Generation of Inhibitors
2011
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes
2000 Standout
Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells
2009
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
2009
COPI-independent Anterograde Transport: Cargo-selective ER to Golgi Protein Transport in Yeast COPI Mutants
1997
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Works of Marjo Simonen being referenced
Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
2008
The BH3 Domain of Bax is Sufficient for Interaction of Bax with itself and with other Family Members and it is Required for Induction of Apoptosis
1997
SH3GLB, a New Endophilin-Related Protein Family Featuring an SH3 Domain
2001
Selective retention of secretory proteins in the yeast endoplasmic reticulum by treatment of cells with a reducing agent
1994
Nogo-A-Deficient Mice Reveal Strain-Dependent Differences in Axonal Regeneration
2006
High-Content Assay to Study Protein Prenylation
2008
Structural Basis of BFL-1 for Its Interaction with BAX and Its Anti-apoptotic Action in Mammalian and Yeast Cells
2000
Systemic Deletion of the Myelin-Associated Outgrowth Inhibitor Nogo-A Improves Regenerative and Plastic Responses after Spinal Cord Injury
2003
Nogo-A Inhibits Neurite Outgrowth and Cell Spreading with Three Discrete Regions
2003
The hsp150 delta-carrier confers secretion competence to the rat nerve growth factor receptor ectodomain in Saccharomyces cerevisiae.
1996
Nogo-A expressed in Schwann cells impairs axonal regeneration after peripheral nerve injury
2002
The hsp150Δ-carrier confers secretion competence to the rat nerve growth factor receptor ectodomain in Saccharomyces cerevisiae
1996