Citation Impact
Citing Papers
G Protein-Coupled Receptor APJ and Its Ligand Apelin Act Downstream of Cripto to Specify Embryonic Stem Cells Toward the Cardiac Lineage Through Extracellular Signal-Regulated Kinase/p70S6 Kinase Signaling Pathway
2009
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.
2013
Oxidative stress and autophagy: the clash between damage and metabolic needs
2014 Standout
The G Protein-Coupled Receptor Agtrl1b Regulates Early Development of Myocardial Progenitors
2007
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Making new contacts: the mTOR network in metabolism and signalling crosstalk
2014
From NASH to HCC: current concepts and future challenges
2019
Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells
2015
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification
2016
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
A Central Role for mTOR in Lipid Homeostasis
2013
Mechanism and medical implications of mammalian autophagy
2018 Standout
Gi-Coupled GPCR Signaling Controls the Formation and Organization of Human Pluripotent Colonies
2009 StandoutNobel
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
A guide to immunometabolism for immunologists
2016 Standout
Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer
2016
Signal integration by mTORC1 coordinates nutrient input with biosynthetic output
2013
Circular RNAs as novel regulators of β-cell functions in normal and disease conditions
2018
Sphingolipids and their metabolism in physiology and disease
2017 Standout
Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch
2013
Targeting inflammation in the treatment of type 2 diabetes: time to start
2014
mTORC2 Promotes Tumorigenesis via Lipid Synthesis
2017
mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion
2017
Hallmarks of aging: An expanding universe
2023 Standout
Rapamycin: One Drug, Many Effects
2014 Standout
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome
2015 Standout
Hepatocellular carcinoma
2021 Standout
Cardiovascular effects of Glucagon-like peptide 1 (GLP-1) receptor agonists
2014
CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity
2019 StandoutNobel
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
2017
Sphingolipids and lifespan regulation
2013
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
2020 StandoutNobel
AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival
2016
SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology
2017
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation
2016
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Mitochondria in the signaling pathways that control longevity and health span
2019
Emerging Role of mTOR in the Response to Cancer Therapeutics
2016
Fluorescence nanoscopy in cell biology
2017 StandoutNobel
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis
2015 Nature
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Macrophages as regulators of tumour immunity and immunotherapy
2019 Standout
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Transcriptional regulation of hepatic lipogenesis
2015
Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation
2018
The biogenesis, biology and characterization of circular RNAs
2019 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Insulin resistance causes inflammation in adipose tissue
2018
Energy Metabolism in the Liver
2014 Standout
The PI3K Pathway in Human Disease
2017 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Ectopic fat, insulin resistance and non-alcoholic fatty liver disease
2013
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway
2016
Autophagy and Aging
2015
NAFLD: A multisystem disease
2015 Standout
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Coordinated regulation of protein synthesis and degradation by mTORC1
2014 Nature
A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation
2015
Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
2018 StandoutNobel
Inflammation in obesity, diabetes, and related disorders
2022 Standout
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
2015 Nature
Mitochondria-Associated Membranes Response to Nutrient Availability and Role in Metabolic Diseases
2016
A growing role for mTOR in promoting anabolic metabolism
2013
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Hypoxia-Induced Apelin Expression Regulates Endothelial Cell Proliferation and Regenerative Angiogenesis
2008
Fundamentals of cancer metabolism
2016 Standout
MicroRNAs in islet hormone secretion
2018
De novolipogenesis in the liver in health and disease: more than just a shunting yard for glucose
2015
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
2015
Rapamycin for longevity: opinion article
2019
The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism
2015
Correlative imaging of ionic transport and electronic structure in nano Li0.5FePO4 electrodes
2019 StandoutNobel
Spatial colocalization and functional link of purinosomes with mitochondria
2016 Science
Hypoxia-Inducible Factor 1 and Cardiovascular Disease
2013 StandoutNobel
Pathophysiology of Type 2 Diabetes Mellitus
2020 Standout
Context-Specific Function of S6K2 in Th Cell Differentiation
2016
Metabolic reprogramming and cancer progression
2020 StandoutScience
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation
2019
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle
2016 Science
Identification and functional analysis of endothelial tip cell–enriched genes
2010
Works of Marion Cornu being referenced
mTOR in aging, metabolism, and cancer
2013
Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c
2012
MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity
2012
Glucagon-like Peptide-1 Increases β-Cell Glucose Competence and Proliferation by Translational Induction of Insulin-like Growth Factor-1 Receptor Expression
2010
Exendin-4 Protects β-Cells From Interleukin-1β–Induced Apoptosis by Interfering With the c-Jun NH2-Terminal Kinase Pathway
2008
Apelin (65‐77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells
2004
Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21
2014
Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis
2013 Science