Citation Impact
Citing Papers
Active Site Tightness and Substrate Fit in DNA Replication
2002
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c- MYC transcription
2002 Standout
Highly Recurrent TERT Promoter Mutations in Human Melanoma
2013 StandoutScience
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Telomerase regulation and stem cell behaviour
2006
Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2′,4′-bridged nucleosides
2008
A Nuclease Hypersensitive Element in the Human c-myc Promoter Adopts Several Distinct i-Tetraplex Structures
2000
MYC on the Path to Cancer
2012 Standout
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells
2002 Standout
Function of the c-Myc Oncogenic Transcription Factor
1999
Arsenic inhibition of telomerase transcription leads to genetic instability
2001
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Oncogenic kinase signalling
2001 StandoutNature
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
A simple and powerful co-delivery system based on pH-responsive metal-organic frameworks for enhanced cancer immunotherapy
2017
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
Tumor suppressors and oncogenes in cellular senescence☆
2000
Hallmarks of aging: An expanding universe
2023 Standout
Telomerase activation by histone deacetylase inhibitor in normal cells
2001
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Cellular Senescence in Cancer and Aging
2007 Standout
Repression of p15INK4b expression by Myc through association with Miz-1
2001
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Telomeres and telomerase in cancer
2009
The Pin2/TRF1-Interacting Protein PinX1 Is a Potent Telomerase Inhibitor
2001
Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells
2009
The Hallmarks of Cancer
2000 Standout
Expression profile of telomerase subunits in human pleural mesothelioma
2000
Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade
2002 StandoutScience
Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors
2005 Standout
Natural and pharmacological regulation of telomerase
2002
Involvement of 14-3-3 proteins in nuclear localization of telomerase
2000
c-MYC: more than just a matter of life and death
2002
Enzymatic Primer-Extension with Glycerol-Nucleoside Triphosphates on DNA Templates
2009 StandoutNobel
Loop-mediated isothermal amplification of DNA
2000 Standout
Interaction of Retroviral Reverse Transcriptase with Template–Primer Duplexes during Replication
1997
Papillomaviruses and cancer: from basic studies to clinical application
2002 StandoutNobel
Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors 1 1Edited by J. Karn
2001
Bmi1, stem cells, and senescence regulation
2004
Direct regulation of TWIST by HIF-1α promotes metastasis
2008
Self-assembling protein nanoparticles in the design of vaccines
2015
How to make a melanoma: what do we know of the primary clonal events?
2008
Apoptosis
2002 Standout
Role of Residues in the Tryptophan Repeat Motif for HIV-1 Reverse Transcriptase Dimerization
2003
Modelling the molecular circuitry of cancer
2002
Properties of strand displacement synthesis by moloney murine leukemia virus reverse transcriptase: mechanistic implications
1998
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
TGFβ in Cancer
2008 Standout
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA
2004 StandoutNobel
c-myc Suppression in Burkitt's Lymphoma Cells
2002
The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance
2001
Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
2002 StandoutNobel
Ectopic Expression of the Catalytic Subunit of Telomerase Protects against Brain Injury Resulting from Ischemia and NMDA-Induced Neurotoxicity
2004
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
Synthetically modified DNAs as substrates for polymerases
2000
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
A critical role for telomeres in suppressing and facilitating carcinogenesis
2000
Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals
2007 Standout
Cellular lifespan and senescence signaling in embryonic stem cells
2004
Advances in Malignant Mesothelioma
2005 Standout
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Cell senescence and cancer
2001
Novel c‐MYC target genes mediate differential effects on cell proliferation and migration
2006
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Kinetic Analysis of an Efficient DNA-Dependent TNA Polymerase
2005 StandoutNobel
Multifaceted Immunomodulatory Nanoliposomes: Reshaping Tumors into Vaccines for Enhanced Cancer Immunotherapy
2017
Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9
2002 StandoutNobel
Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence
2003 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Role of the p53-homologue p73 in E2F1-induced apoptosis
2000
Antibodies in HIV-1 Vaccine Development and Therapy
2013 Science
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Cutting Edge: Telomerase Activation in Human T Lymphocytes Does Not Require Increase in Telomerase Reverse Transcriptase (hTERT) Protein But Is Associated with hTERT Phosphorylation and Nuclear Translocation
2001
Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1
2007 StandoutNobel
Bmi1, stem cells, and senescence regulation
2004
The Myc/Max/Mad Network and the Transcriptional Control of Cell Behavior
2000
Computer simulations of protein functions: Searching for the molecular origin of the replication fidelity of DNA polymerases
2005 StandoutNobel
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
2004 StandoutNobel
Arsenic inhibition of telomerase transcription leads to genetic instability
2001
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
2007 Standout
The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo.
2002
Transcriptional Activation of the Telomerase hTERT Gene by Human Papillomavirus Type 16 E6 Oncoprotein
2001
STRUCTURAL INSIGHTS INTO TRANSLATIONAL FIDELITY
2005 StandoutNobel
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Design of MKC-442 (Emivirine) Analogues with Improved Activity Against Drug-Resistant HIV Mutants
1999
Works of Mario Amacker being referenced
A new and versatile virosomal antigen delivery system to induce cellular and humoral immune responses
2007
Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges
2011
A virosomal vaccine against candidal vaginitis: Immunogenicity, efficacy and safety profile in animal models
2012
Chimeric HIV-1 and feline immunodeficiency virus reverse transcriptases: critical role of the p51 subunit in the structural integrity of heterodimeric lentiviral DNA polymerases
1998
Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions
1997
Probing interactions between HIV-1 reverse transcriptase and its DNA substrate with backbone-modified nucleotides
1999
Ectopic Human Telomerase Catalytic Subunit Expression Maintains Telomere Length But Is Not Sufficient for CD8+ T Lymphocyte Immortalization
2000
Direct activation of TERT transcription by c-MYC
1999
Randomized Phase I: Safety, Immunogenicity and Mucosal Antiviral Activity in Young Healthy Women Vaccinated with HIV-1 Gp41 P1 Peptide on Virosomes
2013
Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity.
2001
Feline immunodeficiency virus reverse transcriptase: expression, functional characterization, and reconstitution of the 66- and 51-kilodalton subunits
1995
Virosome engineering of colloidal particles and surfaces: bioinspired fusion to supported lipid layers
2016