Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
Evolving Concepts in G Protein-Coupled Receptor Endocytosis: The Role in Receptor Desensitization and Signaling
2001 Standout
Association of β-Arrestin with G Protein-coupled Receptors during Clathrin-mediated Endocytosis Dictates the Profile of Receptor Resensitization
1999
β-arrestins: traffic cops of cell signaling
2004 StandoutNobel
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
The Highly Conserved DRY Motif of Class A G Protein-Coupled Receptors: Beyond the Ground State
2006
Cloning and Expression of a Novel Mammalian Homolog ofDrosophila Transient Receptor Potential (Trp) Involved in Calcium Entry Secondary to Activation of Receptors Coupled by the Gq Class of G Protein
1997
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Regulation of V2 Vasopressin Receptor Degradation by Agonist-promoted Ubiquitination
2003 StandoutNobel
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
1995 StandoutNatureNobel
Structural requirements for V2 vasopressin receptor proteolytic cleavage
1999
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain
1987 Standout
The TRPC3 Channel Has a Large Internal Chamber Surrounded by Signal Sensing Antennas
2006
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
2007 StandoutNatureNobel
A Peptide Derived from a β2-Adrenergic Receptor Transmembrane Domain Inhibits Both Receptor Dimerization and Activation
1996
Involvement of Gs and Gi Proteins in Dual Coupling of the Luteinizing Hormone Receptor to Adenylyl Cyclase and Phospholipase C
1996
Rapid gating and anion permeability of an intracellular aquaporin
1999 StandoutNatureNobel
Insulin-induced β-Arrestin1 Ser-412 Phosphorylation Is a Mechanism for Desensitization of ERK Activation by Gαi-coupled Receptors
2004
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL
1999 Nature
Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and ß-arrestin proteins
2002
Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors
1995 StandoutNatureNobel
A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty
1993 Nature
A new wave of serotonin receptors
1993 StandoutNobel
The MMTV LTR Promoter is Induced by Progesterone and Dihydrotestosterone but not by Estrogen
1988
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
The versatility and universality of calcium signalling
2000 Standout
N-Formyl Peptide Receptors Internalize but Do Not Recycle in the Absence of Arrestins
2003 StandoutNobel
STIMulating store-operated Ca2+ entry
2009
Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
1996
The Membrane Topology of Human Transient Receptor Potential 3 as Inferred from Glycosylation-scanning Mutagenesis and Epitope Immunocytochemistry
1998
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Receptor-activated Ca2+ Influx via Human Trp3 Stably Expressed in Human Embryonic Kidney (HEK)293 Cells
1998
The Nature of the Arrestin·Receptor Complex Determines the Ultimate Fate of the Internalized Receptor
2003 Standout
Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain
1988
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases
1992 StandoutNatureNobel
Serotonin receptors: Subtypes, functional responses and therapeutic relevance
1995
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol
1999 StandoutNature
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Binding of the β2 Adrenergic Receptor toN-Ethylmaleimide-sensitive Factor Regulates Receptor Recycling
2001 StandoutNobel
Aquaporins: water selective channels in biological membranes. Molecular structure and tissue distribution
1994
The TRP Channels, a Remarkably Functional Family
2002
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
Sensing with TRP channels
2005
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Type-specific Sorting of G Protein-coupled Receptors after Endocytosis
2000
I ARC, a Novel Arachidonate-regulated, Noncapacitative Ca2+ Entry Channel
2000
Gene regulation by steroid hormones
1989 Standout
Transmembrane Regions V and VI of the Human Luteinizing Hormone Receptor Are Required for Constitutive Activation by a Mutation in the Third Intracellular Loop
1996 StandoutNobel
Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-dependent Concentration of Urine
1994 Science
Phorbol ester-induced stimulation and phosphorylation of adenylyl cyclase 2.
1994
Aquaporins: Water selective channels in biological membranes. Molecular structure and tissue distribution
1994
Molecular Cloning and Functional Characterization of a Novel Receptor-activated TRP Ca2+ Channel from Mouse Brain
1998
Role of the Rate of Internalization of the Agonist-Receptor Complex on the Agonist-Induced Down-Regulation of the Lutropin/ Choriogonadotropin Receptor
1999
Identification of cysteine 656 as the amino acid of hepatoma tissue culture cell glucocorticoid receptors that is covalently labeled by dexamethasone 21-mesylate.
1987
The c-erb-A gene encodes a thyroid hormone receptor
1986 Nature
Regulation of G-Protein-Coupled Receptor Activity by Rab GTPases
2002
Mutations in aquaporin-1 in Phenotypically Normal Humans Without Functional CHIP Water Channels
1994 StandoutScienceNobel
Molecular Cloning of Human and Rat Complementary DNA Encoding Androgen Receptors
1988 Science
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane.
1995
Carcinogenesis: A superfamily of potentially oncogenic hormone receptors
1986 Nature
TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes
2003
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Structure of the chromosomal chicken progesterone receptor gene.
1987
Molecular Cloning of Complementary DNA Encoding the Avian Receptor for Vitamin D
1987 Science
Identification of Two Distinct Structural Motifs That, When Added to the C-Terminal Tail of the Rat LH Receptor, Redirect the Internalized Hormone-Receptor Complex from a Degradation to a Recycling Pathway
2001
Enhanced Myocardial Function in Transgenic Mice Overexpressing the β 2 -Adrenergic Receptor
1994 StandoutScienceNobel
Regulation of TRP Channels via Lipid Second Messengers
2003
Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails
1998 StandoutScienceNobel
The TRP Superfamily of Cation Channels
2005
Hormonal regulation and identification of chicken progesterone receptor phosphorylation sites.
1990
A dileucine motif in the C terminus of the β 2 -adrenergic receptor is involved in receptor internalization
1997
The c-erb-A protein is a high-affinity receptor for thyroid hormone
1986 Nature
Sequence-specific "gene signatures" can beobtained by PCR with single specific primers at low stringency.
1994
Regulation of GPCRs by Endocytic Membrane Trafficking and Its Potential Implications
2007
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor
1987 Nature
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
Purification from bovine liver membranes of a guanine nucleotide-dependent activator of phosphoinositide-specific phospholipase C. Immunologic identification as a novel G-protein alpha subunit.
1990
Mutational Analysis of the Highly Conserved Arginine within the Glu/Asp-Arg-Tyr Motif of the α1b-Adrenergic Receptor: Effects on Receptor Isomerization and Activation
2000
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation.
2000
Regulation of Inducible and Tissue-Specific Gene Expression
1987 Science
Efficacy of beta 1-adrenergic receptors is lower than that of beta 2-adrenergic receptors.
1993
Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA
1987
Inhibition of Adenylyl Cyclase by G iα
1993 StandoutScienceNobel
A novel mutation of the luteinizing hormone receptor gene causing male gonadotropin-independent precocious puberty.
1995
A nuclear 'fossil' of the mitochondrial D-loop and the origin of modern humans
1995 StandoutNatureNobel
The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.
1987
A Heat-Sensitive TRP Channel Expressed in Keratinocytes
2002 StandoutScienceNobel
Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus
2000
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
Expression of TRPC3 in Chinese Hamster Ovary Cells Results in Calcium-activated Cation Currents Not Related to Store Depletion
1997
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Diversity of G Proteins in Signal Transduction
1991 StandoutScience
Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits
1991 StandoutScienceNobel
Works of Mariel Birnbaumer being referenced
Sensitization of Adenylyl Cyclase by P2 Purinergic and M5 Muscarinic Receptor Agonists in L Cells
1991
An expanded V2 receptor retention signal
2002
Maturation of Receptor Proteins in Eukaryotic Expression Systems
1997
Transient Phosphorylation of the V1a Vasopressin Receptor
1998
Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase
1992
Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
1990
Phosphorylation and Recycling Kinetics of g Protein-Coupled Receptors
1999
Homologous desensitization of the murine luteinizing hormone receptor expressed in L cells
1995
The Long and the Short Cycle
2001
Molecular cloning of the receptor for human antidiuretic hormone
1992 Nature
Molecular identification of the gene responsible for congenital nephrogenic diabetes insipidus
1992 Nature
Phosphorylation of the V2 Vasopressin Receptor
1997
Arrestin Effects on Internalization of Vasopressin Receptors
2001
Heterologous Inhibition of G Protein-coupled Receptor Endocytosis Mediated by Receptor-specific Trafficking of β-Arrestins
2001
Properties of the human arginine vasopressin V2 receptor after site-directed mutagenesis of its putative palmitoylation site
1996
Biochemical Basis of Partial Nephrogenic Diabetes Insipidus Phenotypes
1997
Minireview: Mutations and Diseases of G Protein Coupled Receptors
1995
Nature and recurrence of AVPR2 mutations in X-linked nephrogenic diabetes insipidus.
1994
On the molecular basis and regulation of cellular capacitative calcium entry: Roles for Trp proteins
1996
A serine cluster prevents recycling of the V2 vasopressin receptor
1998
Molecular Cloning of the Chicken Progesterone Receptor
1986 Science
Molecular Basis of Regulation of Ionic Channels by G Proteins
1989
Modulation of Ca 2+ entry by polypeptides of the inositol 1,4,5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): Evidence for roles of TRP and IP3R in store depletion-activated Ca 2+ entry
1999
V2R Structure and Diabetes Insipidus
2002