Citation Impact
Citing Papers
Activating Mutations in PIK3CB Confer Resistance to PI3K Inhibition and Define a Novel Oncogenic Role for p110β
2016
A First-in-Human, Phase I, Dose-Escalation Study of TAK-117, a Selective PI3Kα Isoform Inhibitor, in Patients with Advanced Solid Malignancies
2017
Combined Inhibition of Both p110α and p110β Isoforms of Phosphatidylinositol 3-Kinase Is Required for Sustained Therapeutic Effect in PTEN-Deficient, ER+ Breast Cancer
2016
Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
2019 Standout
AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules
2015
Intermittent High-Dose Scheduling of AZD8835, a Novel Selective Inhibitor of PI3Kα and PI3Kδ, Demonstrates Treatment Strategies for PIK3CA -Dependent Breast Cancers
2016
The Genetic Landscape and Clonal Evolution of Breast Cancer Resistance to Palbociclib plus Fulvestrant in the PALOMA-3 Trial
2018
Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial
2016 Standout
Measurement of PIP3 Levels Reveals an Unexpected Role for p110β in Early Adaptive Responses to p110α-Specific Inhibitors in Luminal Breast Cancer
2014
Breast cancer
2019 Standout
Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer
2019 StandoutNobel
Estrogen receptor mutations and their role in breast cancer progression
2014
Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer
2015
Safety and tolerability of AZD5363 in Japanese patients with advanced solid tumors
2016
Glutamate receptor ion channels
2005 Standout
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Signal Transduction in Cancer
2015
Break Breast Cancer Addiction by CRISPR/Cas9 Genome Editing
2017
A view on drug resistance in cancer
2019 StandoutNature
Breast cancer
2016 Standout
Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research
2014 Standout
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Advances in metal-induced oxidative stress and human disease
2011 Standout
Predicting treatment resistance and relapse through circulating DNA
2017
Type I iodothyronine deiodinase is a selenocysteine-containing enzyme
1991 StandoutNature
The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program “CASCADE”
2016
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Tumorigenesis: it takes a village
2015
The neurobiology of zinc in health and disease
2005 Standout
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Advances in the treatment of advanced oestrogen-receptor-positive breast cancer
2016
Liquid Biopsies, What We Do Not Know (Yet)
2017
Hepatocellular carcinoma
2021 Standout
Current and future perspectives of liquid biopsies in genomics-driven oncology
2018 Standout
Clinical value of circulating <em>ESR1</em> mutations for patients with metastatic breast cancer: a meta-analysis
2018
Inflammation and tumor progression: signaling pathways and targeted intervention
2021 Standout
The physiological role of zinc as an antioxidant
1990
Targeting apoptosis in cancer therapy
2020 Standout
Calculations of the Distribution of Zinc in a Computer Model of Human Serum
1989
Implementing Genome-Driven Oncology
2017
Oxidative stress as a mediator of apoptosis
1994 Standout
Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy
2015
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092
2015
Broadening horizons: the role of ferroptosis in cancer
2021 Standout
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Treatment for the endocrine resistant breast cancer: Current options and future perspectives
2017
Emerging Biological Principles of Metastasis
2017 Standout
Oxidative mechanisms in the toxicity of metal ions
1995 Standout
PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting
2014
New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
2010 Standout
Coronary Calcium as a Predictor of Coronary Events in Four Racial or Ethnic Groups
2008 Standout
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
Neurobiology of Zinc and Zinc-Containing Neurons
1989
AKT/PKB Signaling: Navigating the Network
2017 Standout
Everolimus plus exemestane for hormone-receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: overall survival results from BOLERO-2
2014
Tansley Review No. 111
2000 Standout
Palbociclib and Letrozole in Advanced Breast Cancer
2016 Standout
The PI3K Pathway in Human Disease
2017 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro
2015 StandoutNobel
Tumour heterogeneity and resistance to cancer therapies
2017 Standout
Feedback and redundancy in receptor tyrosine kinase signaling: relevance to cancer therapies
2014
Beneficial roles of feed additives as immunostimulants in aquaculture: a review
2017 Standout
Breast Cancer Statistics, 2022
2022 Standout
Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
Offline assessment of atherosclerotic coronary calcium from electron beam tomograms.
1995
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells
2016 StandoutNobel
Breast Cancer Treatment
2019 Standout
A Phase Ib Study of Alpelisib (BYL719), a PI3Kα-Specific Inhibitor, with Letrozole in ER+/HER2− Metastatic Breast Cancer
2016
Plasma ESR1 Mutations and the Treatment of Estrogen Receptor–Positive Advanced Breast Cancer
2016
Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer
2015
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Constraints in cancer evolution
2017
Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer
2015
Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy
2016
Phase III Trial Evaluating Letrozole As First-Line Endocrine Therapy With or Without Bevacizumab for the Treatment of Postmenopausal Women With Hormone Receptor–Positive Advanced-Stage Breast Cancer: CALGB 40503 (Alliance)
2016
Thermodynamic binding constants of the zinc-human serum transferrin complex
1983
Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells
2016
Systemic Therapy for Estrogen Receptor–Positive, HER2-Negative Breast Cancer
2020
Thyroid hormone concentrations in selenium deficient and selenium sufficient cattle
1988
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Works of Marie Will being referenced
Rapid Induction of Apoptosis by PI3K Inhibitors Is Dependent upon Their Transient Inhibition of RAS–ERK Signaling
2014
Feedback Suppression of PI3Kα Signaling in PTEN-Mutated Tumors Is Relieved by Selective Inhibition of PI3Kβ
2014
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer
2013
Some factors controlling food intake by zinc-deficient rats
1973
Measurement of zinc flux through plasma in normal and endotoxin-stressed pigs and the effects of Zn supplementation during stress
1981
The assessment of zinc status of an animal from the uptake of65Zn by the cells of whole blood in vitro
1978
Zinc transport proteins in plasma
1981