Citation Impact
Citing Papers
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Premature Senescence Is a Primary Fail-safe Mechanism of ERBB2-Driven Tumorigenesis in Breast Carcinoma Cells
2005
Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases
2004 StandoutNobel
Bioluminescent imaging of Cdk2 inhibition in vivo
2004 StandoutNobel
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
2001 Nature
Replicative senescence: a critical review
2004
Subunits and Substrates of the Anaphase-Promoting Complex
1999
The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells
2002 Standout
Ubiquitin-Proteasome-mediated Degradation of Id1 Is Modulated by MyoD
2004 StandoutNobel
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Bone marrow cells regenerate infarcted myocardium
2001 StandoutNature
The p400 E1A-associated protein is a novel component of the p53 → p21 senescence pathway
2005
Reversal of human cellular senescence: roles of the p53 and p16 pathways
2003
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
1998
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
Senescence of human fibroblasts induced by oncogenic Raf
1998 Nobel
Repression of p15INK4b expression by Myc through association with Miz-1
2001
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Ki-67 expression during rat liver regeneration after partial hepatectomy
1997
Adult Cardiac Stem Cells Are Multipotent and Support Myocardial Regeneration
2003 Standout
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Three Different Binding Sites of Cks1 Are Required for p27-Ubiquitin Ligation
2002 StandoutNobel
Unattached Kinetochores Catalyze Production of an Anaphase Inhibitor that Requires a Mad2 Template to Prime Cdc20 for BubR1 Binding
2009
Regulation of cellular senescence by p53
2001
Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors
2005 Standout
Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase- promoting complex at mitosis
1998
Gene Ontology: tool for the unification of biology
2000 Standout
Regulation of the APC and the exit from mitosis
1999
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Binding of Activated Cyclosome to p13
1997 StandoutNobel
PKA and MPF-Activated Polo-like Kinase Regulate Anaphase-Promoting Complex Activity and Mitosis Progression
1998
DNA Damage, Aging, and Cancer
2009 Standout
The Cyclin-Ubiquitin Ligase Activity of Cyclosome/APC Is Jointly Activated by Protein Kinases Cdk1-Cyclin B and Plk
2002 StandoutNobel
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Contribution of p16INK4a to replicative senescence of human fibroblasts
2004
Nrk, an X-linked Protein Kinase in the Germinal Center Kinase Family, Is Required for Placental Development and Fetoplacental Induction of Labor
2011 StandoutNobel
Cancer and ageing: rival demons?
2003
Expression Profiles of p53-, p16INK4a-, and Telomere-Regulating Genes in Replicative Senescent Primary Human, Mouse, and Chicken Fibroblast Cells
2002
The essence of senescence: Figure 1.
2010 Standout
The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2
1998
Tumor Suppressor and Aging Biomarker p16INK4a Induces Cellular Senescence without the Associated Inflammatory Secretory Phenotype
2011
MCM proteins: evolution, properties, and role in DNA replication
1998
Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia
1997 StandoutNobel
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
1998
Regulating S Phase: CDKs, Licensing and Proteolysis
1996 StandoutNobel
Microarray analysis of replicative senescence
1999
Telomere Shortening Is an in Vivo Marker of Myocyte Replication and Aging
2000
p16INK4a can initiate an autonomous senescence program
2000
TGFβ in Cancer
2008 Standout
INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence
2002
The anaphase-promoting complex: it's not just for mitosis any more
2002
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
2005 StandoutNature
Genes involved in senescence and immortalization
2000
Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact
2000
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Id proteins in cell cycle control and cellular senescence
2001
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
The Ki-67 protein: From the known and the unknown
2000 Standout
Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies
2012
The role of senescent cells in ageing
2014 StandoutNature
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
2005 StandoutNature
The Hallmarks of Aging
2013 Standout
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Global quantification of mammalian gene expression control
2011 StandoutNature
Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock
2004
Association of pKi-67 with satellite DNA of the human genome in early G1 cells
1998
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
2001 Standout
Cellular senescence and cancer
1999
Cellular senescence as a tumor-suppressor mechanism
2001
A High Glycolytic Flux Supports the Proliferative Potential of Murine Embryonic Stem Cells
2007
Control of the Replicative Life Span of Human Fibroblasts by p16 and the Polycomb Protein Bmi-1
2002
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1999 StandoutNobel
Cell senescence and hypermitogenic arrest
2003
Effects of p21Waf1/Cip1/Sdi1on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases
2000
Biallelic Mutations in p16INK4a Confer Resistance to Ras- and Ets-Induced Senescence in Human Diploid Fibroblasts
2002
Role of p14ARF in Replicative and Induced Senescence of Human Fibroblasts
2001
Aging, Cellular Senescence, and Cancer
2012 Standout
The p16<SUP>INK4a</SUP>-RB pathway : molecular link between cellular senescence and tumor suppression
2004
Structure–activity relationship of truncated and substituted analogues of the intracellular delivery vector Penetratin
2000
Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence
2003 Standout
20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway
1996 Nature
Differential Roles for Cyclin-Dependent Kinase Inhibitors p21 and p16 in the Mechanisms of Senescence and Differentiation in Human Fibroblasts
1999 Standout
MCM Proteins in DNA Replication
1999
Aging and Genome Maintenance: Lessons from the Mouse?
2003 Science
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
Cellular senescence as a tumor-suppressor mechanism
2001
Lack of Replicative Senescence in Normal Rodent Glia
2001 Science
Four faces of cellular senescence
2011 Standout
Regulation of a Senescence Checkpoint Response by the E2F1 Transcription Factor and p14ARF Tumor Suppressor
2000
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
The Anaphase-Promoting Complex: New Subunits and Regulators
1999
How Proteolysis Drives the Cell Cycle
1996 Science
Chmadrin: A novel Ki-67 antigen-related perichromosomal protein possibly implicated in higher order chromatin structure
1999
Schizosaccharomyces pombe cdc 20 + encodes DNA polymerase ɛ and is required for chromosomal replication but not for the S phase checkpoint
1997 StandoutNobel
Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy
2003
PML is induced by oncogenicrasand promotes premature senescence
2000
Two S-phase checkpoint systems, one involving the function of both BIME and Tyr15 phosphorylation of p34cdc2, inhibit NIMA and prevent premature mitosis.
1996
Localisation of the Ki-67 antigen within the nucleolus: Evidence for a fibrillarin-deficient region of the dense fibrillar component
1996
Cell cycle control of replication initiation in eukaryotes
1996
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast
1997
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
BS69 is involved in cellular senescence through the p53–p21Cip1 pathway
2007
Chromatin binding, nuclear localization and phosphorylation of Xenopus cdc21 are cell-cycle dependent and associated with the control of initiation of DNA replication.
1996
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Cell Cycle Checkpoints: Preventing an Identity Crisis
1996 StandoutScience
Works of Maria Starborg being referenced
A Subunit of the Anaphase-Promoting Complex Is a Centromere-Associated Protein in Mammalian Cells
1998
Features of replicative senescence induced by direct addition of antennapedia‐p16INK4A fusion protein to human diploid fibroblasts
1998
Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
1998
The murine Ki-67 cell proliferation antigen accumulates in the nucleolar and heterochromatic regions of interphase cells and at the periphery of the mitotic chromosomes in a process essential for cell cycle progression
1996
A murine replication protein accumulates temporarily in the heterochromatic regions of nuclei prior to initiation of DNA replication
1995
A novel murine gene encoding a 216-kDa protein is related to a mitotic checkpoint regulator previously identified in Aspergillus nidulans.
1994
The murine replication protein P1 is differentially expressed during spermatogenesis.
1995