Standout Papers
Citation Impact
Citing Papers
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
2009 Standout
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway
2009
p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
2010
p62 and NDP52 Proteins Target Intracytosolic Shigella and Listeria to Different Autophagy Pathways
2011
Human PLU-1 Has Transcriptional Repression Properties and Interacts with the Developmental Transcription Factors BF-1 and PAX9
2003
Hallmarks of Cancer: The Next Generation
2011 Standout
Regulation of Autophagy by the p300 Acetyltransferase
2009
Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response†
2008
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
2008
The role of the Atg1/ULK1 complex in autophagy regulation
2010 Standout
Autophagy and NF-κB: Fight for fate
2007
Autophagy and antigen presentation
2006
Autophagy in infection, inflammation and immunity
2013 Standout
A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates
2009
Mitochondria removal by autophagy
2011
mTOR Signaling in Growth Control and Disease
2012 Standout
A Role for Ubiquitin in Selective Autophagy
2009
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
2009
LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy
2012
Autophagy in the liver
2008
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
2010 Standout
Autophagic pathways and metabolic stress
2010
Deletion of Autophagy-related 5 (Atg5) and Pik3c3 Genes in the Lens Causes Cataract Independent of Programmed Organelle Degradation
2013
The LC3 interactome at a glance
2013
Coronaviruses Hijack the LC3-I-Positive EDEMosomes, ER-Derived Vesicles Exporting Short-Lived ERAD Regulators, for Replication
2010
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
2008 Nature
Autophagy in mammalian development and differentiation
2010 Standout
Autophagy regulates lipid metabolism
2009 StandoutNature
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease
2008
Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site
2013
Selective Transport of α-Mannosidase by Autophagic Pathways
2010 StandoutNobel
The Cvt pathway as a model for selective autophagy
2010
Structural Basis for Sorting Mechanism of p62 in Selective Autophagy
2008
Eaten alive: a history of macroautophagy
2010 Standout
p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy
2007 Standout
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Comprehensive proteomics analysis of autophagy-deficient mouse liver
2008
Selective Transport of α-Mannosidase by Autophagic Pathways
2010 StandoutNobel
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
2009
Autophagy Activation Clears ELAVL1/HuR-Mediated Accumulation of SQSTM1/p62 during Proteasomal Inhibition in Human Retinal Pigment Epithelial Cells
2013
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
2010
Unveiling the roles of autophagy in innate and adaptive immunity
2007
Role of autophagy in cancer
2007 Standout
Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes
2009
Autophagy-deficient mice develop multiple liver tumors
2011
Atg8‐family interacting motif crucial for selective autophagy
2010 StandoutNobel
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
2010
Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways
2008
Roles of SIRT1 in the Acute and Restorative Phases following Induction of Inflammation
2010
Induction of Autophagy in Axonal Dystrophy and Degeneration
2006
Innate and Adaptive Immunity through Autophagy
2007
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
2006 StandoutNature
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
2007
TGF -activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy
2011
Autophagosome formation: core machinery and adaptations
2007 Standout
Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
2009 StandoutNobel
Selective autophagy mediated by autophagic adapter proteins
2011 Standout
Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
2010
Protein quality control and degradation in cardiomyocytes
2008
Structure of a Cell Polarity Regulator, a Complex between Atypical PKC and Par6 PB1 Domains
2004
ATG12 Conjugation to ATG3 Regulates Mitochondrial Homeostasis and Cell Death
2010
Autophagy gone awry in neurodegenerative diseases
2010
Viral Mediated Redirection of NEMO/IKKγ to Autophagosomes Curtails the Inflammatory Cascade
2012
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo
2010
Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance
2010
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
2010
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease
2008
Sequestosome 1/p62 – More than just a scaffold
2006
T Helper 2 Cytokines Inhibit Autophagic Control of Intracellular Mycobacterium tuberculosis
2007
Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation
2009
Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance
2010
Delivery of Cytosolic Components by Autophagic Adaptor Protein p62 Endows Autophagosomes with Unique Antimicrobial Properties
2010
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
2001 StandoutNature
Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover
2009
Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins
2011
Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation
2010
Non-ATP competitive protein kinase inhibitors as anti-tumor therapeutics
2009
Selective autophagy: ubiquitin-mediated recognition and beyond
2010
Methods in Mammalian Autophagy Research
2010 Standout
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
2010
Chapter 12 Monitoring Autophagic Degradation of p62/SQSTM1
2009
LC3 and GATE‐16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
2010
A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery
2011
p62 expression and autophagy in αB-crystallin R120G mutant knock-in mouse model of hereditary cataract
2013
Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration
2010
Structural basis of target recognition by Atg8/LC3 during selective autophagy
2008 StandoutNobel
Autophagy Protects against Sindbis Virus Infection of the Central Nervous System
2010
A block of autophagy in lysosomal storage disorders
2007
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
Epigallocatechin Gallate (EGCG) Stimulates Autophagy in Vascular Endothelial Cells
2013
A Picky Eater: Exploring the Mechanisms of Selective Autophagy in Human Pathologies
2007
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The role of senescent cells in ageing
2014 StandoutNature
TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation
2012
Autophagy: process and function
2007 Standout
The Hallmarks of Aging
2013 Standout
Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
2008
Toward unraveling membrane biogenesis in mammalian autophagy
2008
Unique Structural and Functional Properties of the ATP-binding Domain of Atypical Protein Kinase C-ι
2000
Dynamics and diversity in autophagy mechanisms: lessons from yeast
2009 StandoutNobel
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Toll‐like receptors control autophagy
2008
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
2010 Standout
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
2013
Signaling, Polyubiquitination, Trafficking, and Inclusions: Sequestosome 1/p62′s Role in Neurodegenerative Disease
2006
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Listeria monocytogenes ActA-mediated escape from autophagic recognition
2009
Autophagy in immunity and inflammation
2011 StandoutNature
SEPA-1 Mediates the Specific Recognition and Degradation of P Granule Components by Autophagy in C. elegans
2009
The atypical PKC-interacting protein p62 channels NF-kappa B activation by the IL-1-TRAF6 pathway
2000
Exosomes in Cancer Liquid Biopsy: A Focus on Breast Cancer
2017
Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
2009
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
2007
The yeasts Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane
2003 StandoutNobel
Selective autophagy
2013
Measurement of Autophagy in Cells and Tissues
2010
Calpain is required for macroautophagy in mammalian cells
2006
Lysosome-mediated processing of chromatin in senescence
2013
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
2008
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
2011
Regulation Mechanisms and Signaling Pathways of Autophagy
2009 Standout
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
2008 Standout
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
2007
Endogenous HMGB1 regulates autophagy
2010
How to Live Long and Prosper: Autophagy, Mitochondria, and Aging
2008
The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes
2008
Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG
2008
Atg19 Mediates a Dual Interaction Cargo Sorting Mechanism in Selective Autophagy
2006
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation
2015 StandoutNobel
E-Syts, a family of membranous Ca 2+ -sensor proteins with multiple C 2 domains
2007 StandoutNobel
The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
2013
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
2008
Regulation of innate immune responses by autophagy-related proteins
2010
Molecular Analysis Reveals Localization ofSaccharomyces cerevisiaeProtein Kinase C to Sites of Polarized Growth and Pkc1p Targeting to the Nucleus and Mitotic Spindle
2005
Sequestosome 1/p62 Is a Polyubiquitin Chain Binding Protein Involved in Ubiquitin Proteasome Degradation
2004
Localization of Atypical Protein Kinase C Isoforms into Lysosome-Targeted Endosomes through Interaction with p62
1998
An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure
2008
Protein Turnover Via Autophagy: Implications for Metabolism
2007
Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease
2010
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
2008
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
2014 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Autophagy: Basic Principles and Relevance to Disease
2008
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes
2008
Autophagy inhibition promotes defective neosynthesized proteins storage in ALIS, and induces redirection toward proteasome processing and MHCI-restricted presentation
2012
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Maria Perander being referenced
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
2005 Standout
Zebrafish Pax9 Encodes Two Proteins with Distinct C-terminal Transactivating Domains of Different Potency Negatively Regulated by Adjacent N-terminal Sequences
1996
Nuclear Import and Export Signals Enable Rapid Nucleocytoplasmic Shuttling of the Atypical Protein Kinase C λ
2001
Distinct Small RNA Signatures in Extracellular Vesicles Derived from Breast Cancer Cell Lines
2016
Interaction Codes within the Family of Mammalian Phox and Bem1p Domain-containing Proteins
2003
Reversion of Ras- and Phosphatidylcholine-hydrolyzing Phospholipase C-mediated Transformation of NIH 3T3 Cells by a Dominant Interfering Mutant of Protein Kinase C λ Is Accompanied by the Loss of Constitutive Nuclear Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Activity
1997