Citation Impact
Citing Papers
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Identification of FIP200 interaction with the TSC1–TSC2 complex and its role in regulation of cell size control
2005
TOR Signaling in Growth and Metabolism
2006 Standout
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
2016
TSC1 Activates TGF-β-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition
2015
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
2015 StandoutNobel
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Triple-Negative Breast Cancer
2010 Standout
Tuberous Sclerosis Complex 2 Gene Product Interacts with Human SMAD Proteins
2004
Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate
2011
Methods for Physical Characterization of Phase-Separated Bodies and Membrane-less Organelles
2018
The Tuberous Sclerosis Complex
2006 Standout
Effect of rapamycin on aging and age-related diseases—past and future
2020
The p38 and MK2 Kinase Cascade Phosphorylates Tuberin, the Tuberous Sclerosis 2 Gene Product, and Enhances Its Interaction with 14-3-3
2003
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus
2020
TSC1 controls macrophage polarization to prevent inflammatory disease
2014
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
mTOR regulates memory CD8 T-cell differentiation
2009 Nature
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Multicompartmental distribution of the tuberous sclerosis gene products, hamartin and tuberin
2002
Hallmarks of aging: An expanding universe
2023 Standout
Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner
2005
Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display
2015
The TSC-mTOR pathway regulates macrophage polarization
2013
Immunoregulatory functions of mTOR inhibition
2009
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
2005 Standout
Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis
2008 Standout
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
In Vivo Maturation of Functional Renal Organoids Formed from Embryonic Cell Suspensions
2012
Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy
2007 StandoutNobel
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Immune surveillance of tumors
2007
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Regulation of mTORC1 by PI3K signaling
2015
The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence
2015
The role of mTOR in memory CD8+ T‐cell differentiation
2010
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
2016 StandoutNobel
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
Regulation of innate immune cell function by mTOR
2015
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
Phosphorylation and Functional Inactivation of TSC2 by Erk
2005 Standout
Lymphangioleiomyomatosis — a wolf in sheep’s clothing
2012
mTOR: taking cues from the immune microenvironment
2009
Immunity, Inflammation, and Cancer
2010 Standout
TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
2012
Control of macrophage metabolism and activation by mTOR and Akt signaling
2015
U1 snRNP regulates cancer cell migration and invasion in vitro
2020 Standout
Tuberous sclerosis
2008 Standout
PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation by Regulating Gfi1 Expression and Nuclear Translocation of RORγ
2012
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
2009
Drosophila, the golden bug, emerges as a tool for human genetics
2005
Emerging Biological Principles of Metastasis
2017 Standout
Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
2010
Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR
2013
Tuberous Sclerosis: from Tubers to mTOR
2003
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Macrophage mTORC1 disruption reduces inflammation and insulin resistance in obese mice
2014
T Cell Surveillance of Oncogene-Induced Prostate Cancer Is Impeded by T Cell-Derived TGF-β1 Cytokine
2011 StandoutNobel
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
The Neurobiology of the Tuberous Sclerosis Complex
2006
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages
2010
Insulin signaling pathways in cortical dysplasia and TSC‐tubers: Tissue microarray analysis
2004
AKT/PKB Signaling: Navigating the Network
2017 Standout
Host Translation at the Nexus of Infection and Immunity
2012
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
The PI3K Pathway in Human Disease
2017 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
mTOR and cancer: insights into a complex relationship
2006
Epileptogenesis and Reduced Inward Rectifier Potassium Current in Tuberous Sclerosis Complex‐1–Deficient Astrocytes
2005
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
2004 Standout
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells
2008 Science
Rapamycin unbalances the polarization of human macrophages to M 1
2013
Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA
2016
TSC2: filling the GAP in the mTOR signaling pathway
2003
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Allelochemics: Chemical Interactions between Species
1971 StandoutScience
mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation
2015
Quantum Shells Boost the Optical Gain of Lasing Media
2022 StandoutNobel
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Spermidine in health and disease
2018 StandoutScience
Regulation of Immune Responses by mTOR
2012
The TSC1–TSC2 complex: a molecular switchboard controlling cell growth
2008 Standout
Negative Regulation of TSC1-TSC2 by Mammalian D-Type Cyclins
2005
2012
Inhibitors of the mammalian target of rapamycin
2005
mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS
2010
Phase 2 study of idelalisib and entospletinib: pneumonitis limits combination therapy in relapsed refractory CLL and NHL
2016
Lymphangioleiomyomatosis
2006
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling
2009
Friends Not Foes: CTLA-4 Blockade and mTOR Inhibition Cooperate during CD8+ T Cell Priming To Promote Memory Formation and Metabolic Readiness
2015 StandoutNobel
Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1
2009
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
mTOR Pathway as a Target in Tissue Hypertrophy
2006
Toxins in Plant Disease: Structure and Mode of Action
1969 Science
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors.
2002
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning
2006
Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates
2014
The Role of Atg Proteins in Autophagosome Formation
2011 StandoutNobel
Works of Margit Rosner being referenced
Brca1 regulates in vitro differentiation of mammary epithelial cells
2002
The tuberous sclerosis gene products hamartin and tuberin are multifunctional proteins with a wide spectrum of interacting partners
2008
Inhibition of mTOR down-regulates scavenger receptor, class B, type I (SR-BI) expression, reduces endothelial cell migration and impairs nitric oxide production
2014
mTOR phosphorylated at S2448 binds to raptor and rictor
2009
Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1
2008
Detection of Cytoplasmic and Nuclear Functions of mTOR by Fractionation
2011
FAS (CD95) Mutations Are Rare in Gastric MALT Lymphoma but Occur More Frequently in Primary Gastric Diffuse Large B-Cell Lymphoma
2004
Tuberous sclerosis causing mutants of the TSC2 gene product affect proliferation and p27 expression
2001
Nuclear/cytoplasmic localization of Akt activity in the cell cycle
2007
Evidence for Separable Functions of Tuberous Sclerosis Gene Products in Mammalian Cell Cycle Regulation
2002
mTORC1 Is Essential for Early Steps during Schwann Cell Differentiation of Amniotic Fluid Stem Cells and Regulates Lipogenic Gene Expression
2014
Tuberous sclerosis genes regulate cellular 14-3-3 protein levels
2003
Cell size regulation by the human TSC tumor suppressor proteins depends on PI3K and FKBP38
2003
Tuberin Binds p27 and Negatively Regulates Its Interaction with the SCF Component Skp2
2004
Tuberous sclerosis gene products in proliferation control
2001
Proteins interacting with the tuberous sclerosis gene products
2004
Merging high-quality biochemical fractionation with a refined flow cytometry approach to monitor nucleocytoplasmic protein expression throughout the unperturbed mammalian cell cycle
2013
Cell cycle and cell size regulation in Down Syndrome cells
2003
Akt regulates nuclear/cytoplasmic localization of tuberin
2006
In vitro cell migration and invasion assays
2012
Contribution of human amniotic fluid stem cells to renal tissue formation depends on mTOR
2010
p38α Senses Environmental Stress To Control Innate Immune Responses via Mechanistic Target of Rapamycin
2013
The tuberous sclerosis genes, TSC1 and TSC2, trigger different gene expression responses
2005
Welkstoffe und Antibiotika. 18. Mitteilung Diaporthin, ein Welketoxin aus Kulturen von Endothia parasitica (Murr.) And
1957
The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response
2008
The cell cycle and tuberous sclerosis.
2003
Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells
2011
The cellular response to ectopic overexpression of the tuberous sclerosis genes, TSC1 and TSC2: a proteomic approach.
2005