Citation Impact
Citing Papers
Rapid protein fold determination using unassigned NMR data
2003 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
2024 StandoutNobel
Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex
2008
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand
2002 Standout
Mechanisms of Thrombus Formation
2008 Standout
Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator
1998
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Inference of Macromolecular Assemblies from Crystalline State
2007 Standout
The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht
1999 Standout
The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin
1997
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Focal adhesion kinase: in command and control of cell motility
2005 Standout
Additivity in Effects of Vitronectin and Monoclonal Antibodies against α-Helix F of Plasminogen Activator Inhibitor-1 on Its Reactions with Target Proteinases
2004
Analysis of protein-protein interaction sites using surface patches 1 1Edited by G.Von Heijne
1997
Insights into MMP‐TIMP Interactions
1999
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
2022 StandoutNobel
Haemophilia B: database of point mutations and short additions and deletions, 7th edition
1997
Endoproteinase‐protein inhibitor interactions
1999
Computational Design of Novel Protein Binders and Experimental Affinity Maturation
2013 StandoutNobel
DipoCoup: A versatile program for 3D-structure homology comparison based on residual dipolar couplings and pseudocontact shifts
2000
Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold – A Potential Therapeutic Intervention for Skin Diseases
2016 StandoutNobel
Lysine 156promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA
1997
Zinc coordination sphere in biochemical zinc sites
2001
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Electrostatics in protein–protein docking
2002
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
An Orientation-dependent Hydrogen Bonding Potential Improves Prediction of Specificity and Structure for Proteins and Protein–Protein Complexes
2003 StandoutNobel
Design, Activity, and Structure of a Highly Specific Artificial Endonuclease
2002 StandoutNobel
Hotspot-Centric De Novo Design of Protein Binders
2011 StandoutNobel
Structure of the Ultra-High-Affinity Colicin E2 DNase–Im2 Complex
2012 StandoutNobel
Structural Basis of the Zinc Inhibition of Human Tissue Kallikrein 5
2007 Nobel
Physiology of Local Renin-Angiotensin Systems
2006 Standout
Amazing Diversity in Biochemical Roles of Fe(II)/2-Oxoglutarate Oxygenases
2018
Synthetic glycopeptides and glycoproteins as tools for biology
2004 StandoutNobel
The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor
1996 Nature
Computational Design of a New Hydrogen Bond Network and at Least a 300-fold Specificity Switch at a Protein−Protein Interface
2006 StandoutNobel
Protein–Protein Docking with Simultaneous Optimization of Rigid-body Displacement and Side-chain Conformations
2003 StandoutNobel
Molecular Analysis of Ulilysin, the Structural Prototype of a New Family of Metzincin Metalloproteases
2006
Future challenges facing the development of specific active-site-directed synthetic inhibitors of MMPs
2004
A player of many parts: The spotlight falls on thrombin's structure
1993
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Roles of N-Linked Glycans in the Endoplasmic Reticulum
2004 Standout
No Effect of Clot Age or Thrombolysis on Argatroban’s Inhibition of Thrombin
1998
Serpin Structure, Mechanism, and Function
2002 Standout
1,2-Benzisothiazol-3-one 1,1-Dioxide Inhibitors of Human Mast Cell Tryptase
1998
A Coagulation Factor IX-Deficient Mouse Model for Human Hemophilia B
1997 StandoutNobel
The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities.
1996 Nobel
Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle
2001 StandoutNobel
Direct Measurement of Angles Between Bond Vectors in High-Resolution NMR
1997 Science
Mapping epitopes and antigenicity by site-directed masking
2006 StandoutNobel
Comparative Analysis of Haemostatic Proteinases: Structural Aspects of Thrombin, Factor Xa, Factor IXa and Protein C
1997
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Thermodynamics of Unfolding for Kazal-Type Serine Protease Inhibitors: Entropic Stabilization of Ovomucoid First Domain by Glycosylation
1997
Update 1 of: Proteases Universally Recognize Beta Strands In Their Active Sites
2010
Homogeneous Glycopeptides and Glycoproteins for Biological Investigation
2002 StandoutNobel
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Contributions of Amino Acid Side Chains to the Kinetics and Thermodynamics of the Bivalent Binding of Protein L to Ig κ Light Chain
2004 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Architecture and function of metallopeptidase catalytic domains
2013
Wound Healing: A Cellular Perspective
2018 Standout
Protease Inhibitors: Current Status and Future Prospects
2000
De Novo Determination of Protein Backbone Structure from Residual Dipolar Couplings Using Rosetta
2002 StandoutNobel
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases
2003 Standout
Evaluation of Models of Electrostatic Interactions in Proteins
2003 StandoutNobel
New enzyme lineages by subdomain shuffling
1998 Nobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Argatroban Anticoagulant Therapy in Patients With Heparin-Induced Thrombocytopenia
2001 Standout
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
The ornithodorin-thrombin crystal structure, a key to the TAP enigma?
1996 Nobel
A simple physical model for binding energy hot spots in protein–protein complexes
2002 StandoutNobel
Modulating protein stability – directed evolution strategies for improved protein function
2013
Works of Margit Bauer being referenced
Screening for soluble expression constructs using cell-free protein synthesis
2006
The Three-dimensional Structure of Recombinant Leech-derived Tryptase Inhibitor in Complex with Trypsin
1997 Nobel
Crystallographic Determination of Thrombin Complexes With Small Synthetic Inhibitors as a Starting Point for the Receptor-Based Design of Antithrombotics
1993
The 2.3 Å Crystal Structure of the Catalytic Domain of Recombinant Two-chain Human Tissue-type Plasminogen Activator
1996 Nobel
Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation
2000
Crystallographic Evidence That the F2 Kringle Catalytic Domain Linker of Prothrombin Does Not Cover the Fibrinogen Recognition Exosite
1996
Crystal Structure of a Complex BetweenSerratia marcescensMetallo-protease and an Inhibitor fromErwinia chrysanthemi
1995
Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor 1 1Edited by I. Wilson
2001
Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
1995 Nobel
X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B.
1995