Citation Impact
Citing Papers
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Roles of tau protein in health and disease
2017
Membrane curvature regulates the spatial distribution of bulky glycoproteins
2022 StandoutNobel
Elucidating Tau function and dysfunction in the era of cryo-EM
2019
Aminothienopyridazines and Methylene Blue Affect Tau Fibrillization via Cysteine Oxidation
2013
Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
2014
Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment
2010
Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies
2012
Alternative Conformations of the Tau Repeat Domain in Complex with an Engineered Binding Protein
2014
Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation
2015
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
2009
Therapeutic strategies for tau mediated neurodegeneration
2012
Conformation-variable PDI@β-sheet nanohelices show stimulus-responsive supramolecular chirality
2013
Recent advances in our understanding of neurodegeneration
2009
O-GlcNAc Modification of tau Directly Inhibits Its Aggregation without Perturbing the Conformational Properties of tau Monomers
2014
Biomarkers of neurodegeneration for diagnosis and monitoring therapeutics
2007
Alzheimer Mechanisms and Therapeutic Strategies
2012
Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Beta-1a for Multiple Sclerosis
2005 Standout
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity
2012
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
2007 Standout
Evaluating triggers and enhancers of tau fibrillization
2005
Autophagic degradation of tau in primary neurons and its enhancement by trehalose
2011
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo
2012
Paraneoplastic Syndromes Involving the Nervous System
2003 Standout
Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles
2011
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Alzheimer's disease
2011 Standout
Tau phosphorylation and aggregation in Alzheimer's disease pathology
2006
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
2010 Standout
The Potential for β-Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy
2008
O-Pair Search with MetaMorpheus for O-glycopeptide characterization
2020 StandoutNobel
Crohn's disease
2012 Standout
Are Tangles as Toxic as They Look?
2011
Critical role of JC virus-specific CD4 T-cell responses in preventing progressive multifocal leukoencephalopathy
2003
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
2009
Structural Principles of Tau and the Paired Helical Filaments of Alzheimer’s Disease
2007
Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis
2015 StandoutNobel
Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins
2004
Tau in physiology and pathology
2015 Standout
Synthetic organic dyes as contaminants of the aquatic environment and their implications for ecosystems: A review
2020 Standout
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Untangling tau hyperphosphorylation in drug design for neurodegenerative diseases
2007
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Immunotherapy Targeting Pathological Tau Conformers in a Tangle Mouse Model Reduces Brain Pathology with Associated Functional Improvements
2007
High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation
2007
Dual Inhibitors of β-Amyloid Aggregation and Acetylcholinesterase as Multi-Target Anti-Alzheimer Drug Candidates
2013
Revealing the human mucinome
2022 StandoutNobel
Tau-aggregation inhibitor therapy for Alzheimer's disease
2013
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
2011
Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein Pathology
2014
Glycosylation in health and disease
2019
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
GSPE interferes with tau aggregation in vivo: implication for treating tauopathy
2011
Alzheimer's disease
2016 Standout
BODIPY–Thiophene Copolymers as p‐Channel Semiconductors for Organic Thin‐Film Transistors
2013 StandoutNobel
Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease
2011 StandoutNobel
Alzheimer's Disease
2010 Standout
Risk of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy
2012 Standout
Tau oligomers and aggregation in Alzheimer’s disease
2009
Alzheimer's disease: clinical trials and drug development
2010
In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons
2008
Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis
2010
The ChEMBL database in 2017
2016 Standout
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
2012
The Amyloid State of Proteins in Human Diseases
2012 Standout
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells
2008 StandoutNobel
Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau
2012
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
2012
Towards a Pharmacophore for Amyloid
2011
Differentiating Alzheimer disease-associated aggregates with small molecules
2007
Tau imaging: early progress and future directions
2014
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Advanced Luminescent Materials Based on Organoboron Polymers
2012
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
γ-Secretase and its modulators: Twenty years and beyond
2019
Post-translational modifications of tau protein: Implications for Alzheimer's disease
2011
Structural and functional photoacoustic molecular tomography aided by emerging contrast agents
2014
Cyanine Dye N744 Inhibits Tau Fibrillization by Blocking Filament Extension: Implications for the Treatment of Tauopathic Neurodegenerative Diseases
2005
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
Tau-dependent microtubule disassembly initiated by prefibrillar β-amyloid
2006
Newcastle Disease Virus Expressing a Dendritic Cell-Targeted HIV Gag Protein Induces a Potent Gag-Specific Immune Response in Mice
2010 StandoutNobel
Tau-Targeted Multifunctional Nanocomposite for Combinational Therapy of Alzheimer’s Disease
2018
Tau reduction prevents disease in a mouse model of D ravet syndrome
2014
Supramolecular Chirality in Self-Assembled Systems
2015 Standout
A Century of Alzheimer's Disease
2006 StandoutScience
Intrinsic disorder in proteins associated with neurodegenerative diseases
2009
KEGG: integrating viruses and cellular organisms
2020 Standout
Elucidating the Mechanism of Lipid Membrane-Induced IAPP Fibrillogenesis and Its Inhibition by the Red Wine Compound Resveratrol: A Synchrotron X-ray Reflectivity Study
2009
Immunotherapy Targeting Pathological Tau Protein in Alzheimer's Disease and Related Tauopathies
2008
Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade
2018
Structure-Based Design of Functional Amyloid Materials
2014 StandoutNobel
Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
2020 StandoutNobel
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Degradation of tau protein by autophagy and proteasomal pathways
2012
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Immune response in progressive multifocal leukoencephalopathy: An overview
2001
Atraumatic Oral Spray Immunization with Replication-Deficient Viral Vector Vaccines
2007 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Unusual viral infections (progressive multifocal leukoencephalopathy and cytomegalovirus disease) after high-dose chemotherapy with autologous blood stem cell rescue and peritransplantation rituximab
2002
Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity
2006
The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy
2007
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Designed amyloid fibers as materials for selective carbon dioxide capture
2013 StandoutNobel
Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process
2010
Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores
2018
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Functional signatures of protective antiviral T‐cell immunity in human virus infections
2006
Pathological tau: a loss of normal function or a gain in toxicity?
2005
The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush
2012
Chemistry: Chemical con artists foil drug discovery
2014 StandoutNature
Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice
2016
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Works of Marcus Pickhardt being referenced
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
2015
Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy
2005
Screening for Inhibitors of Tau Polymerization
2005
Tau protein and tau aggregation inhibitors
2010
Development of Tau Aggregation Inhibitors for Alzheimer's Disease
2009
Rhodanine‐Based Tau Aggregation Inhibitors in Cell Models of Tauopathy
2007
Anthraquinones Inhibit Tau Aggregation and Dissolve Alzheimer's Paired Helical Filaments in Vitro and in Cells
2004
“Lest we forget you — methylene blue …”
2011
Screening for Inhibitors of Tau Protein Aggregation into Alzheimer Paired Helical Filaments: A Ligand Based Approach Results in Successful Scaffold Hopping
2007
Mechanistic Basis of Phenothiazine‐Driven Inhibition of Tau Aggregation
2013
N-Phenylamine Derivatives as Aggregation Inhibitors in Cell Models of Tauopathy
2007
Inhibition of Tau Aggregation in Cell Models of Tauopathy
2007
Entwicklung von Inhibitoren der Tau‐Aggregation bei Morbus Alzheimer
2009
Phenylthiazolyl-Hydrazide and Its Derivatives Are Potent Inhibitors of τ Aggregation and Toxicity in Vitro and in Cells
2007
Cellular and humoral immune response in progressive multifocal leukoencephalopathy
2001
The Core of Tau-Paired Helical Filaments Studied by Scanning Transmission Electron Microscopy and Limited Proteolysis
2006
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
2007
Inhibition of Tau Filament Formation by Conformational Modulation
2013
N′-Benzylidene-Benzohydrazides as Novel and Selective Tau-PHF Ligands
2011