Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Social stress shortens lifespan in mice
2018
Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice
2005 StandoutScience
Stimulation of Neurogenesis in the Hippocampus of the Adult Rat by Fluoxetine Requires Rhythmic Change in Corticosterone
2005
Thyroid and adrenal axis in major depression: a controlled study in outpatients
2005
Lithium’s Emerging Role in the Treatment of Refractory Major Depressive Episodes: Augmentation of Antidepressants
2010
Toward a Neuroimaging Treatment Selection Biomarker for Major Depressive Disorder
2013
A Meta-Analysis of Cytokines in Major Depression
2009 Standout
Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression
2003
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: Acute and Continuation Treatment of Major Depressive Disorder
2002
Major Depressive Disorder
2000
Major depressive disorder: new clinical, neurobiological, and treatment perspectives
2011
Influence of Child Abuse on Adult Depression
2008
The Dexamethasone/Corticotropin-Releasing Factor Test in Men with Major Depression: Role of Childhood Trauma
2007
Hypothalamo-pituitary-adrenal function in patients with depressive disorders is correlated with baseline cytokine levels, but not with cytokine responses to hydrocortisone
2003
Cognitive, physiological, and personality correlates of recurrence of depression
2005
Poor replication of candidate genes for major depressive disorder using genome-wide association data
2010
Major depressive disorder is a risk factor for low bone mass, central obesity, and other medical conditions
2011
Predictive Value of Family History on Severity of Illness
2009
A meta-analysis of cognitive deficits in first-episode Major Depressive Disorder
2011
Molecular studies of major depressive disorder: the epigenetic perspective
2007
Pro-inflammatory cytokines and treatment response to escitaloprsam in major depressive disorder
2007
Depression
2018 Standout
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
Major depressive disorder
2016 Standout
HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition
2016
Serotonin and neuroplasticity – Links between molecular, functional and structural pathophysiology in depression
2017
Effects of ghrelin on psychopathology, sleep and secretion of cortisol and growth hormone in patients with major depression
2010
Different responses to dexamethasone and prednisolone in the same depressed patients
2006
Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
2015
Metyrapone as Additive Treatment in Major Depression
2004
The Corticosteroid Receptor Hypothesis of Depression
2000 Standout
Child abuse: Adolescent records vs. adult recall
1990 Standout
Genetic modulation of the pharmacological treatment of pain
2009
Antiglucocorticoid drugs in the treatment of depression
2001
A meta-analysis of depression severity and cognitive function
2009
Biomarkers of depression in cancer patients
2006
Purinergic signalling in inflammation of the central nervous system
2009
Ghrelin signalling and obesity: At the interface of stress, mood and food reward
2012
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Psychobiology and molecular genetics of resilience
2009
Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors
2005
Rewiring of the Fruit Metabolome in Tomato Breeding
2018 Standout
Drug-Dependent Requirement of Hippocampal Neurogenesis in a Model of Depression and of Antidepressant Reversal
2008
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Nucleotide signalling during inflammation
2014 StandoutNature
Chronic inflammation in the etiology of disease across the life span
2019 Standout
(Far) Outside the box: Genomic approach to acute porphyria
2006
Treatment of mood disorders
2002
Delirium in elderly people
2013 Standout
Novel Drugs and Therapeutic Targets for Severe Mood Disorders
2008
Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
2007 Standout
IL-6 knockout mice exhibit resistance to stress-induced development of depression-like behaviors
2006
Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders
2008
Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile
2013
The Flinders Sensitive Line rat: A selectively bred putative animal model of depression
2005
Modulation of the mineralocorticoid receptor as add-on treatment in depression: A randomized, double-blind, placebo-controlled proof-of-concept study
2009
Increased soluble tumor necrosis factor‐α receptors in patients with major depressive disorder
2009
Glucocorticoid Dysregulations and Their Clinical Correlates
2009
Suppression of the MEK/ERK Signaling Pathway Reverses Depression-like Behaviors of CRF2-Deficient Mice
2008
Decision making, impulsivity and time perception
2007
CRF system and mood disorders
2013
Association of FK506 binding protein 5 (FKBP5) gene rs4713916 polymorphism with mood disorders: a meta-analysis
2011
Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression
2010
Porphyrias
2010 Standout
Younger, premenopausal women with major depressive disorder have more abdominal fat and increased serum levels of prothrombotic factors: implications for greater cardiovascular risk
2005
Cognitive impairment in depression: a systematic review and meta-analysis
2013
When Not Enough Is Too Much: The Role of Insufficient Glucocorticoid Signaling in the Pathophysiology of Stress-Related Disorders
2003
Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
2011 Nature
The impact of treatment on HPA axis activity in unipolar major depression
2009
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D)
2012
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Acute Stressors and Cortisol Responses: A Theoretical Integration and Synthesis of Laboratory Research.
2004 Standout
Neuropsychology of timing and time perception
2004
New approaches to antidepressant drug discovery: beyond monoamines
2006
Pathophysiological distortions in time perception and timed performance
2011 Standout
Gut–brain axis: how the microbiome influences anxiety and depression
2013 Standout
Treatment of Somatoform Disorders With St. Johnʼs Wort: A Randomized, Double-Blind and Placebo-Controlled Trial
2004
Pituitary-Adrenal and Autonomic Responses to Stress in Women After Sexual and Physical Abuse in Childhood
2000
Facial shape differences between rats selected for tame and aggressive behaviors
2017 StandoutNobel
Stress and the brain: from adaptation to disease
2005 Standout
Power failure: why small sample size undermines the reliability of neuroscience
2013 Standout
Corticosteroids in relation to fear, anxiety and psychopathology
2001
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Depression in adolescence
2012 Standout
Discovering Endophenotypes for Major Depression
2004
Impact of glucocorticoids on brain function: Relevance for mood disorders
2010
How can we realize the promise of personalized antidepressant medicines?
2008
Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis
2009 Standout
Differential modulation of cytokine production in major depressive disorder by cortisol and dexamethasone
2008
The HPA axis in major depression: classical theories and new developments
2008 Standout
The Cognitive Effects of Antidepressants in Major Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
2015
Partial Normalization of Serum Brain-Derived Neurotrophic Factor in Remitted Patients after a Major Depressive Episode
2005
Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions
2012
The stress system in the human brain in depression and neurodegeneration
2005
Mineralocorticoid Receptor Stimulation Improves Cognitive Function and Decreases Cortisol Secretion in Depressed Patients and Healthy Individuals
2014
Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics
2011
Time perception, depression and sadness
2008
Major Depressive Disorder
2008 Standout
Depression gets old fast: do stress and depression accelerate cell aging?
2010
Meta-analyses of genetic studies on major depressive disorder
2007
The Long-Term Health Consequences of Child Physical Abuse, Emotional Abuse, and Neglect: A Systematic Review and Meta-Analysis
2012 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Cognitive Impairment in Major Depression: Association with Salivary Cortisol
2009
Non-specific low back pain
2011 Standout
The role of immune genes in the association between depression and inflammation: A review of recent clinical studies
2012
Glucocorticoid antagonists in neuropsychotic disorders
2008
Salivary cortisol in depressed patients versus control persons: A systematic review and meta-analysis
2010
From inflammation to sickness and depression: when the immune system subjugates the brain
2007 Standout
The Role of TNF-α in Patients With Chronic Low Back Pain—A Prospective Comparative Longitudinal Study
2008
The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice
2005
Effects of the monoamine oxidase A inhibitor moclobemide on hippocampal plasticity in GR-impaired transgenic mice
2001
Molecular biomarkers of depression
2016
The molecular neurobiology of depression
2008 StandoutNature
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
Can we vaccinate against depression?
2012
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies
2001 Standout
Neuroscience, Molecular Biology, and the Childhood Roots of Health Disparities
2009 Standout
Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression
2007
Erythropoietin: a candidate treatment for mood symptoms and memory dysfunction in depression
2011
Purinergic signalling and disorders of the central nervous system
2008
The Effect of Antidepressant Medication Treatment on Serum Levels of Inflammatory Cytokines: A Meta-Analysis
2011
Correlation Between Serum Brain-Derived Neurotrophic Factor Level and An In Vivo Marker of Cortical Integrity
2007
A critical review of human endotoxin administration as an experimental paradigm of depression
2009
Research and treatment approaches to depression
2001
Neuroendocrine aspects of the response to stress
2002
Low plasma BDNF is associated with suicidal behavior in major depression
2006
The neurobiology of depression and antidepressant action
2012
Cytokine-effects on glucocorticoid receptor function: Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression
2006
Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation
2004
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Transcriptional Control of Monocyte Gene Expression in Post-Traumatic Stress Disorder
2011
Pharmacological interventions for somatoform disorders in adults
2014 Standout
A cytochrome P450 regulates a domestication trait in cultivated tomato
2013
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.
1996 StandoutNobel
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
2012 StandoutNobel
Angst and the amygdala
2006
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
The circadian basis of winter depression
2006
Amyloid, hypometabolism, and cognition in Alzheimer disease
2006
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Receptors for Purines and Pyrimidines
2012 Standout
The glucocorticoid receptor: part of the solution or part of the problem?
2006
Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants
2003 StandoutScience
Biomimetic Screening of Class-B G Protein-Coupled Receptors
2011
EAT-4, a Homolog of a Mammalian Sodium-Dependent Inorganic Phosphate Cotransporter, Is Necessary for Glutamatergic Neurotransmission inCaenorhabditis elegans
1999 StandoutNobel
Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
2013
The neurobiology of depression: inroads to treatment and new drug discovery.
2005
CRF and CRF Receptors: Role in Stress Responsivity and Other Behaviors
2004
Works of Marcus Ising being referenced
Overweight and Obesity Affect Treatment Response in Major Depression
2007
Polymorphisms in GRIK4, HTR2A, and FKBP5 Show Interactive Effects in Predicting Remission to Antidepressant Treatment
2009
P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
2006
Combined Dexamethasone/Corticotropin Releasing Hormone Test Predicts Treatment Response in Major Depression–A Potential Biomarker?
2006
Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated
2000
Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: A translational approach
2014
Treatment of depression with the CRH-1-receptor antagonist R121919: endocrine changes and side effects
2003
Clinical and Neurobiological Effects of Tianeptine and Paroxetine in Major Depression
2003
The Interplay of Familial Depression Liability and Adverse Events in Predicting the First Onset of Depression During a 10-Year Follow-up
2007
Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression
2001
Lithium augmentation increases post-dexamethasone cortisol in the dexamethasone suppression test in unipolar major depression
2003
Polymorphisms of the Glucocorticoid Receptor Gene and Major Depression
2006
A Genomewide Association Study Points to Multiple Loci That Predict Antidepressant Drug Treatment Outcome in Depression
2009
Electroencephalographic sleep profiles in treatment course and long-term outcome of major depression: association with DEX/CRH-test response
2004
Changes of Sleep Architecture, Spectral Composition of Sleep EEG, the Nocturnal Secretion of Cortisol, ACTH, GH, Prolactin, Melatonin, Ghrelin, and Leptin, and the DEX-CRH Test in Depressed Patients during Treatment with Mirtazapine
2005
Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression
2005
High-Affinity CRF1 Receptor Antagonist NBI-34041: Preclinical and Clinical Data Suggest Safety and Efficacy in Attenuating Elevated Stress Response
2007
Pharmacological and Nonpharmacological Factors Influencing Hypothalamic–Pituitary–Adrenocortical Axis Reactivity in Acutely Depressed Psychiatric In-patients, Measured by the Dex-CRH Test
2003
Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls
2008
FK506 Binding Protein 5 Shapes Stress Responsiveness: Modulation of Neuroendocrine Reactivity and Coping Behavior
2011
The combined dexamethasone/CRH test as a potential surrogate marker in depression
2005
Changes in the Hypothalamic-Pituitary-Adrenal Axis and Leptin Levels during Antidepressant Treatment
2007
Depression, comorbidities and the TNF-α system
2008
Association between response to lithium augmentation and the combined DEX/CRH test in major depressive disorder
2003
Polymorphisms in the Drug Transporter Gene ABCB1 Predict Antidepressant Treatment Response in Depression
2008
Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD
2010
CRH₁ receptor antagonists for the treatment of depression and anxiety.
2007
Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks
2009
More CLEC16A gene variants associated with multiple sclerosis
2010
Ghrelin Stimulates Appetite, Imagination of Food, GH, ACTH, and Cortisol, but does not Affect Leptin in Normal Controls
2005
Persistent Cognitive Impairment in Depression: The Role of Psychopathology and Altered Hypothalamic-Pituitary-Adrenocortical (HPA) System Regulation
2006
Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders
2004
Outcome in delusional depression comparing trimipramine monotherapy with a combination of amitriptyline and haloperidol – A double-blind multicenter trial
2008
Central CRH system in depression and anxiety — Evidence from clinical studies with CRH1 receptor antagonists
2008
Successful Antidepressant Therapy Restores the Disturbed Interplay Between TNF-α System and HPA Axis
2006
HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients
2008
Time experience and time judgment in major depression, mania and healthy subjects. A controlled study of 93 subjects
2004
Cognitive impairment in unipolar depression is persistent and non-specific: further evidence for the final common pathway disorder hypothesis
2008
Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - Findings front the Munich antidepressant response signature (MARS) project
2008
Hippocampal metabolic abnormalities in mild cognitive impairment and Alzheimer's disease
2005
Interaction of FKBP5 Gene Variants and Adverse Life Events in Predicting Depression Onset: Results From a 10-Year Prospective Community Study
2011
Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis
2005
Stress Hormone Regulation: Biological Role and Translation into Therapy
2009
Ghrelin promotes slow-wave sleep in humans
2003
Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: A translational approach
2015
The interplay of variations in the FKBP5 gene and adverse life events in predicting the first onset of depression during a ten-year follow-up
2009