Citation Impact
Citing Papers
UV irradiation induces a postreplication DNA damage checkpoint
2006
Diversity and Complexity in DNA Recognition by Transcription Factors
2009 Science
Origins of Specificity in Protein-DNA Recognition
2010
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement
2007 StandoutNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Mechanism of Release and Fate of Excised Oligonucleotides during Nucleotide Excision Repair
2012 StandoutNobel
A dynamic model of proteome changes reveals new roles for transcript alteration in yeast
2011
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
A Multiparameter Network Reveals Extensive Divergence between C. elegans bHLH Transcription Factors
2009
Genomic Regions Flanking E-Box Binding Sites Influence DNA Binding Specificity of bHLH Transcription Factors through DNA Shape
2013
An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
2015 StandoutNobel
Preventing re-replication of chromosomal DNA
2005
The DNA-damage response in human biology and disease
2009 StandoutNature
Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument
2011
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
ELISA–PLA: A novel hybrid platform for the rapid, highly sensitive and specific quantification of proteins and post-translational modifications
2016
BRCA1 Is Required for Postreplication Repair after UV-Induced DNA Damage
2011
From DNA sequence to transcriptional behaviour: a quantitative approach
2009
DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints
2010
The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA
2009
Quantitative Emergence of Hetero[4]rotaxanes by Template‐Directed Click Chemistry
2012 StandoutNobel
The Chk1-mediated S-phase Checkpoint Targets Initiation Factor Cdc45 via a Cdc25A/Cdk2-independent Mechanism
2006
Phosphorylation of replication protein A by S-phase checkpoint kinases
2006
Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase
2009 StandoutNobel
The Rad4TopBP1 ATR-Activation Domain Functions in G1/S Phase in a Chromatin-Dependent Manner
2012
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM
2010
Multiplex pairwise assembly of array-derived DNA oligonucleotides
2015 StandoutNobel
Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression
2008 Standout
Identification of SMARCAL1 as a Component of the DNA Damage Response
2009
Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase η on ATR checkpoint signaling
2006
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
In vitro DNA-binding profile of transcription factors: methods and new insights
2011
ATR: an essential regulator of genome integrity
2008
The Human Transcription Factors
2018 Standout
Multiple Mechanisms Control Chromosome Integrity after Replication Fork Uncoupling and Restart at Irreparable UV Lesions
2006
The FANCM/FAAP24 Complex Is Required for the DNA Interstrand Crosslink-Induced Checkpoint Response
2010
Cistrome: an integrative platform for transcriptional regulation studies
2011
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
DNA Damage, Aging, and Cancer
2009 Standout
Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates
2011 StandoutNobel
Extensive protein and DNA backbone sampling improves structure-based specificity prediction for C2H2 zinc fingers
2011
Survey of the year 2000 commercial optical biosensor literature
2001
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
Formation of Arabidopsis Cryptochrome 2 Photobodies in Mammalian Nuclei
2013 StandoutNobel
The DNA Damage Response: Ten Years After
2007
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
Determining the specificity of protein–DNA interactions
2010
Stalled Fork Rescue via Dormant Replication Origins in Unchallenged S Phase Promotes Proper Chromosome Segregation and Tumor Suppression
2011
PARP is activated at stalled forks to mediate Mre11‐dependent replication restart and recombination
2009
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
The phosphorylated C‐terminal domain of Xenopus Cut5 directly mediates ATR‐dependent activation of Chk1
2006
Direct Role for the Replication Protein Treslin (Ticrr) in the ATR Kinase-mediated Checkpoint Response
2013 StandoutNobel
The Rad9–Hus1–Rad1 (9–1–1) clamp activates checkpoint signaling via TopBP1
2007
UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein–DNA interactions
2014
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Two Distinct Modes of ATR Activation Orchestrated by Rad17 and Nbs1
2013
Mechanism of Stimulation of Human DNA Ligase I by the Rad9-Rad1-Hus1 Checkpoint Complex
2006 StandoutNobel
The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks
2009
Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA
2009
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
A tale of two tails: Activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1
2009
Cdc7-Dbf4 and the Human S Checkpoint Response to UVC
2007 StandoutNobel
BLM–DNA2–RPA–MRN and EXO1–BLM–RPA–MRN constitute two DNA end resection machineries for human DNA break repair
2011 StandoutNobel
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
2012
Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair
2008
The structural determinants of checkpoint activation
2007
Survey of the year 2003 commercial optical biosensor literature
2004
Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase
2009 StandoutNobel
Different gene regulation strategies revealed by analysis of binding motifs
2009
Comprehensive Genome-wide Protein-DNA Interactions Detected at Single-Nucleotide Resolution
2011
Mammalian TIMELESS and Tipin are Evolutionarily Conserved Replication Fork-associated Factors
2006
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
The checkpoint response to replication stress
2009
TopBP1 Activates the ATR-ATRIP Complex
2006
A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment
2013
Analysis of Ribonucleotide Removal from DNA by Human Nucleotide Excision Repair
2015 StandoutNobel
Evaluation of methods for modeling transcription factor sequence specificity
2013
The Rad9-Hus1-Rad1 Checkpoint Clamp Regulates Interaction of TopBP1 with ATR
2007
Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication
2010
Survey of the year 2001 commercial optical biosensor literature
2002
Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)
2011 StandoutNobel
Characterization of functional domains in human Claspin
2011
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
DNA Repair Synthesis and Ligation Affect the Processing of Excised Oligonucleotides Generated by Human Nucleotide Excision Repair
2014 StandoutNobel
Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress
2009
TopBP1 and DNA polymerase-α directly recruit the 9-1-1 complex to stalled DNA replication forks
2009
Hbo1 Links p53-Dependent Stress Signaling to DNA Replication Licensing
2007
Mechanisms for Initiating Cellular DNA Replication
2013
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication
2011
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
DNA Replication in the Archaea
2006
Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns
2010
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Function of a Conserved Checkpoint Recruitment Domain in ATRIP Proteins
2007
Massively parallel measurements of molecular interaction kinetics on a microfluidic platform
2012
Eukaryotic DNA Replication Fork
2017
ATR signalling: more than meeting at the fork
2011
Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control
2011
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Cell-cycle-specific activators of the Mec1/ATR checkpoint kinase
2011
Physical Interaction between Replication Protein A (RPA) and MRN: Involvement of RPA2 Phosphorylation and the N-Terminus of RPA1
2009
The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling
2008
In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling
2012 StandoutNobel
Replication protein A: directing traffic at the intersection of replication and repair
2010
DNA structure-specific priming of ATR activation by DNA-PKcs
2013
Quality control in the initiation of eukaryotic DNA replication
2011
Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts
2007 Nobel
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis
2009
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Phosphorylation ofXenopusRad1 and Hus1 Defines a Readout for ATR Activation That Is Independent of Claspin and the Rad9 Carboxy Terminus
2006
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Recruitment of DNA Damage Checkpoint Proteins to Damage in Transcribed and Nontranscribed Sequences
2005 StandoutNobel
Works of Marcin Pacek being referenced
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
2005
Interactions of DnaA Proteins from Distantly Related Bacteria with the Replication Origin of the Broad Host Range Plasmid RK2
2000
DnaA Box Sequences as the Site for Helicase Delivery during Plasmid RK2 Replication Initiation in Escherichia coli
2001
Localization of MCM2-7, Cdc45, and GINS to the Site of DNA Unwinding during Eukaryotic DNA Replication
2006
High-resolution DNA-binding specificity analysis of yeast transcription factors
2009
A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication
2004
A simple and portable device for the quantification of TNF-α in human plasma by means of on-chip magnetic bead-based proximity ligation assay
2013