Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
2012 StandoutScience
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
2015 StandoutScience
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Intracellular Innate Immune Cascades and Interferon Defenses That Control Hepatitis C Virus
2009
Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly
2013
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)
2015 StandoutNobel
Pan-Genotype Hepatitis E Virus Replication in Stem Cell–Derived Hepatocellular Systems
2017 StandoutNobel
Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling
2015 StandoutNobel
Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
2013
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
2011
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Oncology Meets Immunology: The Cancer-Immunity Cycle
2013 Standout
Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA
2013
Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment
2013
Structural and Functional Analyses of DNA-Sensing and Immune Activation by Human cGAS
2013
Hepatitis C Virus Core-Derived Peptides Inhibit Genotype 1b Viral Genome Replication via Interaction with DDX3X
2010
Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor
2012
Use of the Pharmacological Inhibitor BX795 to Study the Regulation and Physiological Roles of TBK1 and IκB Kinase ϵ
2009
Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation
2013
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
2013 StandoutNature
Mitochondrion: an emerging platform critical for host antiviral signaling
2011
Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion
2010
Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity
2011
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3
2015 StandoutNobel
Structural mechanism of cytosolic DNA sensing by cGAS
2013 Nature
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
Activation and regulation of the inflammasomes
2013 Standout
Cytosolic Sensing of Viruses
2013
Activation of host pattern recognition receptors by viruses
2010
STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
2014
Regulation of immunity and oncogenesis by the IRF transcription factor family
2010
The roles of TLRs, RLRs and NLRs in pathogen recognition
2009
Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3
2008
DEAD/H BOX 3 (DDX3) helicase binds the RIG‐I adaptor IPS‐1 to up‐regulate IFN‐β‐inducing potential
2010
Crosstalk between the cGAS DNA Sensor and Beclin-1 Autophagy Protein Shapes Innate Antimicrobial Immune Responses
2014
Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment
2010
The molecular machinery of regulated cell death
2019 Standout
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
2012
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
2014 StandoutNobel
Intracellular Toll-like Receptors
2010 StandoutNobel
Mitochondria: In Sickness and in Health
2012 Standout
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
AIM2 Facilitates the Apoptotic DNA-induced Systemic Lupus Erythematosus via Arbitrating Macrophage Functional Maturation
2013
Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children
2016 Standout
IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
2011
Molecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STING
2014
Regulation of inflammasome signaling
2012
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
2010 Standout
Autophagy in Human Health and Disease
2013 Standout
Cardiac glycosides are potent inhibitors of interferon-β gene expression
2010
The PYRIN domain–only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses
2014
Age-related macular degeneration
2018 Standout
Immune Sensing of DNA
2013
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
Genetic variation in Toll-like receptors and disease susceptibility
2012
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Autophagy and Aging
2011 Standout
Sterile inflammation: sensing and reacting to damage
2010 Standout
Innate Immune Recognition of an AT-Rich Stem-Loop DNA Motif in the Plasmodium falciparum Genome
2011
Mechanisms and Functions of Inflammasomes
2014 Standout
The broad-spectrum antiviral functions of IFIT and IFITM proteins
2012
Newly described pattern recognition receptors team up against intracellular pathogens
2013
Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
2013
Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing
2013
Inflammation and its role in age-related macular degeneration
2016
5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential
2012
The Ded1/DDX3 subfamily of DEAD-box RNA helicases
2014
Tumor-derived exosomes antagonize innate antiviral immunity
2018
Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system
2012
Innate Immune Responses to Hepatitis C Virus
2013 StandoutNobel
Intrinsic antiviral immunity
2012
STING is a direct innate immune sensor of cyclic di-GMP
2011 Nature
Inflammasomes in health and disease
2012 StandoutNature
ATP-Dependent Effector-like Functions of RIG-I-like Receptors
2015 StandoutNobel
DNA Repair Synthesis and Ligation Affect the Processing of Excised Oligonucleotides Generated by Human Nucleotide Excision Repair
2014 StandoutNobel
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides
2010
DDX60, a DEXD/H Box Helicase, Is a Novel Antiviral Factor Promoting RIG-I-Like Receptor-Mediated Signaling
2011
Recognition of nucleic acids by pattern‐recognition receptors and its relevance in autoimmunity
2011
Viral evasion and subversion of pattern-recognition receptor signalling
2008
Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids
2014
DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking
2013
Human Cytomegalovirus Induces the Interferon Response via the DNA Sensor ZBP1
2009
IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV
2013 Science
STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway
2012
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy
2013
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
A Virological View of Innate Immune Recognition
2012
Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation
2017
2015
Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid
2013
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
2012
DEAD-Box Helicases: Sensors, Regulators, and Effectors for Antiviral Defense
2020
Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKϵ and DDX3
2010
DEAD-box helicases: the Yin and Yang roles in viral infections
2018
AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity
2015
cGAS and Ifi204 Cooperate To Produce Type I IFNs in Response to Francisella Infection
2015
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP
2011
Histone Deacetylases in Herpesvirus Replication and Virus-Stimulated Host Defense
2013
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
The DNA Sensor, Cyclic GMP–AMP Synthase, Is Essential for Induction of IFN-β during Chlamydia trachomatis Infection
2014
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion
2016 StandoutNobel
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
2018 StandoutNobel
Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects
2013 Science
Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune Pathways
2017
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Marcin Baran being referenced
Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKε‐mediated IRF activation
2008
IFI16 is an innate immune sensor for intracellular DNA
2010
Cytosolic DNA sensors regulating type I interferon induction
2011