Citation Impact
Citing Papers
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
2009 Standout
Infection, inflammation, height, and longevity
2005 Standout
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans
2008 StandoutScienceNobel
Phospholipid methylation controls Atg32‐mediated mitophagy and Atg8 recycling
2015 StandoutNobel
Thematic review series: The Pathogenesis of Atherosclerosis. Effects of infection and inflammation on lipid and lipoprotein metabolism mechanisms and consequences to the host
2004
Lipid and metabolic syndrome traits in coronary artery disease: a Mendelian randomization study
2020
Rationale and design of the Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes (PROMINENT) study
2018
Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease
2012
Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I
2006
Inflammation and metabolic disorders
2006 StandoutNature
Effects of Torcetrapib in Patients at High Risk for Coronary Events
2007 Standout
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
2014 StandoutNature
The metabolic syndrome
2010 Standout
Transcriptional regulatory networks in lipid metabolism control ABCA1 expression
2005
Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter
2006
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits
2007
Molecular biology of PCSK9: its role in LDL metabolism
2007
Interaction between high-density lipoproteins and inflammation: Function matters more than concentration!
2020
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice
2005
Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice
2012
Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
2009
The changing landscape of atherosclerosis
2021 StandoutNature
Atherosclerosis: current pathogenesis and therapeutic options
2011 Standout
Microbiota-induced obesity requires farnesoid X receptor
2016
A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits
2000 Nature
Farnesoid X receptor is essential for normal glucose homeostasis
2006
Bile acid sequestrants
2011
Regulation of Complement C3 Expression by the Bile Acid Receptor FXR
2004
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
Metazoan MicroRNAs
2018 Standout
Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study
2002
The metabolic syndrome
2005 Standout
Comparative α‐Helicity of Cyclic Pentapeptides in Water
2014
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Constraining Cyclic Peptides To Mimic Protein Structure Motifs
2014
The immunology of atherosclerosis
2017
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR
2012
Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?
2010
SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis
2019 Nature
Membranes in Balance: Mechanisms of Sphingolipid Homeostasis
2010
Update on strategies to increase HDL quantity and function
2009
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Gene variants, insulin resistance, and dyslipidaemia
2004
Mitochondrial Quality Control Mediated by PINK1 and Parkin: Links to Parkinsonism
2012 Nobel
The Human ATP-Binding Cassette (ABC) Transporter Superfamily
2001
Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
2015
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
2014 Standout
Identification of Sterol-independent Regulatory Elements in the Human ATP-binding Cassette Transporter A1 Promoter
2002
A Spectrum of PCSK9 Alleles Contributes to Plasma Levels of Low-Density Lipoprotein Cholesterol
2006
FXR Agonists as Therapeutic Agents for Non-alcoholic Fatty Liver Disease
2015
β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice
2009 StandoutNobel
Hepatitis C Virus Entry
2007 StandoutNobel
Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
2016 Standout
Expanding perspectives on the significance of mitophagy in cancer
2017
An emerging role of PARK2 in cancer
2013
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Hepatic FXR: key regulator of whole-body energy metabolism
2011
Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
2003
Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
2016
Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis
2011 Standout
Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure
2011
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms
2003
The Emergence of the Metabolic Syndrome with Menopause
2003
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Atherosclerosis
2001 Standout
Sequence Variations in PCSK9, Low LDL, and Protection against Coronary Heart Disease
2006 Standout
Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism
2003
Stimulation of Cholesterol Excretion by the Liver X Receptor Agonist Requires ATP-binding Cassette Transporters G5 and G8
2003
Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP
2012
Bifidobacteria can protect from enteropathogenic infection through production of acetate
2011 StandoutNature
Bile acid receptors as targets for drug development
2013
Tissue-specific function of farnesoid X receptor in liver and intestine
2011
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice
2007
Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events
2015 Standout
Prevalence of metabolic syndrome in an urban population: Tehran Lipid and Glucose Study
2003
HIF-1beta determines ABCA1 expression under hypoxia in human macrophages
2009 StandoutNobel
MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 ( Srebp2 ) regulates HDL in vivo
2010
Diagnosis and Management of the Metabolic Syndrome
2005 Standout
Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism
2018
Macrophage ATP-Binding Cassette Transporter A1 Overexpression Inhibits Atherosclerotic Lesion Progression in Low-Density Lipoprotein Receptor Knockout Mice
2006
The Role of the High-Density Lipoprotein Receptor SR-BI in the Lipid Metabolism of Endocrine and Other Tissues
2003
Deciphering the nuclear bile acid receptor FXR paradigm
2010
The history of proprotein convertase subtilisin kexin-9 inhibitors and their role in the treatment of cardiovascular disease
2020
Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies
2010
The Problem of Passenger Genes in Transgenic Mice
2007
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Evidence for a New Pathophysiological Mechanism for Coronary Artery Disease Regression
1999
A Role of the Bile Salt Receptor FXR in Atherosclerosis
2010
Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal
2014
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity
2011
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Macrophage Reverse Cholesterol Transport
2006
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia
2018 Standout
Abdominal Obesity and Dyslipidemia in the Metabolic Syndrome: Importance of Type 2 Diabetes and Familial Combined Hyperlipidemia in Coronary Artery Disease Risk
2004
LXRS AND FXR: The Yin and Yang of Cholesterol and Fat Metabolism
2005
Mammalian ABC Transporters in Health and Disease
2002
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Interleukin‐10 overexpression in macrophages suppresses atherosclerosis in hyperlipidemic mice
2010
Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
2003
Niacin, but Not Gemfibrozil, Selectively Increases LP-AI, a Cardioprotective Subfraction of HDL, in Patients With Low HDL Cholesterol
2001
Combined Deletion of Macrophage ABCA1 and ABCG1 Leads to Massive Lipid Accumulation in Tissue Macrophages and Distinct Atherosclerosis at Relatively Low Plasma Cholesterol Levels
2007
Hepatic lipase promotes the selective uptake of high density lipoprotein-cholesteryl esters via the scavenger receptor B1
1999
Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake
2011 Standout
Cholesteryl Ester Transfer Protein
2003
SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR
2006
Hepatocyte Nuclear Factor 4α (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis
2001
Comparative α‐Helicity of Cyclic Pentapeptides in Water
2014
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption
2004 StandoutScience
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Works of Marcelo Amar being referenced
Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells
2005
Hepatic lipase facilitates the selective uptake of cholesteryl esters from remnant lipoproteins in apoE-deficient mice
1998
Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations
2003
ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice
2001
Enhanced ABCG1 expression increases atherosclerosis in LDLr-KO mice on a western diet
2006
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells
2011
A cholesterol-lowering VLP vaccine that targets PCSK9
2015
Apolipoprotein mimetic peptides: Mechanisms of action as anti-atherogenic agents
2010
Sphingosine 1-Phosphate Lyase Deficiency Disrupts Lipid Homeostasis in Liver
2010
The Farnesoid X-receptor Is an Essential Regulator of Cholesterol Homeostasis
2003
Apolipoprotein C-II: New findings related to genetics, biochemistry, and role in triglyceride metabolism
2017
Lecithin: cholesterol acyltransferase – from biochemistry to role in cardiovascular disease
2009
Fluorescent pegylated nanoparticles demonstrate fluid-phase pinocytosis by macrophages in mouse atherosclerotic lesions
2009
Effects of FXR in foam-cell formation and atherosclerosis development
2006
Cholesteryl Ester Transfer Protein Corrects Dysfunctional High Density Lipoproteins and Reduces Aortic Atherosclerosis in Lecithin Cholesterol Acyltransferase Transgenic Mice
1999
The role of hepatic lipase in lipoprotein metabolism and atherosclerosis
1998
ABCA1 Overexpression in the Liver of LDLr-KO Mice Leads to Accumulation of Pro-atherogenic Lipoproteins and Enhanced Atherosclerosis
2006
5A Apolipoprotein Mimetic Peptide Promotes Cholesterol Efflux and Reduces Atherosclerosis in Mice
2010
Helix stabilization of amphipathic peptides by hydrocarbon stapling increases cholesterol efflux by the ABCA1 transporter
2011
Comparison of Omega-3 Eicosapentaenoic Acid Versus Docosahexaenoic Acid-Rich Fish Oil Supplementation on Plasma Lipids and Lipoproteins in Normolipidemic Adults
2020
Hepatic lipase deficiency decreases the selective uptake of HDL-cholesteryl esters in vivo
2000
The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene
2002
ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice
2001
Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice
2015
The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice
2001
In Vivo Evidence for Both Lipolytic and Nonlipolytic Function of Hepatic Lipase in the Metabolism of HDL
2000
Contribution of Macromolecular Structure to the Retention of Low-Density Lipoprotein at Arterial Branch Points
2008