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Citing Papers
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Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene
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1993
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1998
Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning
1993
A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome
1990
Cloning theDrosophilahomolog of the xeroderma pigmentosum complementation group C gene reveals homology between the predicted human andDrosophilapolypeptides and that encoded by the yeastRAD4gene
1994
Protein regulation by monoubiquitin
2001
NUCLEOTIDE EXCISION REPAIR
1993 StandoutNobel
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II
1994 Nature
Oncoprotein Networks
1997
Sturcture and expression of the humanXPBC/ERCC-3gene involved in DNA repair disorders xeroderma pigmentosum and Cockayne's syndrome
1991
Poly(ADP-ribose) polymerase interacts with a novel human ubiquitin conjugating enzyme: hUbc9
1997
The Hallmarks of Cancer
2000 Standout
Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 4
2000
Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence
1997
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast
1994 StandoutNatureNobel
DNA helicases: Enzymes with essential roles in all aspects of DNA metabolism
1994
Yeast excision repair gene RAD2 encodes a single-stranded DNA endonuclease
1993 Nature
Purification and Characterization of the XPF-ERCC1 Complex of Human DNA Repair Excision Nuclease
1995 StandoutNobel
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3
1992
A Drosophila model for xeroderma pigmentosum and Cockayne's syndrome: haywire encodes the fly homolog of ERCC3, a human excision repair gene
1992
Nucleotide excision repair II: from yeast to mammals
1993
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Human xeroderma pigmentosum group D gene encodes a DMA helicase
1993 Nature
DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly(ADP-ribose) Polymerase
1999
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1997 StandoutNature
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
1992
The human ubiquitin‐conjugating enzyme UbcH1 is involved in the repair of UV‐damaged, alkylated and cross‐linked DNA
1994
Role of poly(ADP-ribose) formation in DNA repair
1992 StandoutNatureNobel
Alternative Antigen Receptor (TCR) Signaling in T Cells Derived from ZAP-70-deficient Patients Expressing High Levels of Syk
2000
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
1993 StandoutNobel
Dynamics and mechanism of repair of ultraviolet-induced (6–4) photoproduct by photolyase
2010 StandoutNatureNobel
Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9
1996
THE UBIQUITIN-CONJUGATION SYSTEM
1992
RAD25 is a DMA helicase required for DNA repair and RNA polymerase II transcription
1994 Nature
Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts
1988
Structure of the human DNA ligast I gene
1992 StandoutNobel
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
1994 StandoutNatureNobel
Somatic cell genetics approach to dissecting mammalian DNA repair
1989
Conserved XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway Selection of Transcription or Excision Repair
2006
The human REV1 gene codes for a DNA template-dependent dCMP transferase
1999
On the origin, evolution, and nature of programmed cell death: a timeline of four billion years
2002
Xeroderma Pigmentosum Group F Caused by a Defect in a Structure-Specific DNA Repair Endonuclease
1996
Cohesin Rec8 is required for reductional chromosome segregation at meiosis
1999 StandoutNatureNobel
Hypoxia inducible factor (HIF) function in innate immunity and infection
2007
mei-3, a recombination and repair gene of Neurospora crassa, encodes a RecA-like protein
1993
Lysosome-targeting chimaeras for degradation of extracellular proteins
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Novel Human and Mouse Homologs of Saccharomyces cerevisiae DNA Polymerase η
1999
Regulating protein degradation by ubiquitination
1997
Physical Interaction between Specific E2 and Hect E3 Enzymes Determines Functional Cooperativity
1997
Isolation of the functional human excision repair gene ERCC5 by intercosmid recombination
1990
A ubiquitin-like system mediates protein lipidation
2000 StandoutNatureNobel
Yeast DNA repair and recombination proteins Rad1 and Rad1O constitute a single-stranded-DNA endonuclease
1993 Nature
Molecular mechanism of nucleotide excision repair
1999
An interaction between the Tfb1 and SsI1 subunits of yeast TFIIH correlates with DNA repair activity
1995
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
Assignment of the gene encoding DNA ligase I to human chromosome 19q13.2–13.3
1992 StandoutNobel
The Drosophila meiotic recombination gene mei-9 encodes a homologue of the yeast excision repair protein Rad1.
1995
Rad3 protein of Saccharomyces cerevisiae: Overexpression and preliminary characterization using specific antibodies
1988
Identification of a Family of Closely Related Human Ubiquitin Conjugating Enzymes
1995
Stable and specific association between the yeast recombination and DNA repair proteins RAD1 and RAD10 in vitro.
1992
Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27
1995 StandoutScience
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Degradation of Proteins with Acetylated Amino Termini by the Ubiquitin System
1989 StandoutScienceNobel
Molecular Cloning and Biological Characterization of a Human Gene, ERCC2, that Corrects the Nucleotide Excision Repair Defect in CHO UV5 Cells
1988
DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor
1993 Science
Specific complex formation between proteins encoded by the yeast DNA repair and recombination genes RAD1 and RAD10.
1992
The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor.
1994
Molecular Cloning of the Human XRCC1 Gene, Which Corrects Defective DNA Strand Break Repair and Sister Chromatid Exchange
1990
Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair.
1994
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
A Ubiquitin Mutant with Specific Defects in DNA Repair and Multiubiquitination
1995
Characterization of the RAD10 gene of Saccharomyces cerevisiae and purification of Rad10 protein
1990
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Ubiquitin–mediated proteolysis and male sterility
1996 StandoutNobel
Interleukin-4 (IL-4) inhibits secretion of IL-1 beta, tumor necrosis factor alpha, and IL-6 by human monocytes
1990
Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.
1994
Rad51 expression and localization in B cells carrying out class switch recombination.
1996
Quality Control by DNA Repair
1999 StandoutScienceNobel
Purification and characterization of the Saccharomyces cerevisiae RAD1/RAD10 endonuclease.
1993
RNA Polymerase II Initiation Factor Interactions and Transcription Start Site Selection
1994 StandoutScienceNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Specific association between the human DNA repair proteins XPA and ERCC1.
1994
The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair.
1994
Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH).
1994
Human ERCC5 cDNA-cosmid complementation for excision repair and bipartite amino acid domains conserved with RAD proteins of Saccharomyces cerevisiae and Schizosaccharomyces pombe.
1993
The future of cloning
1999 StandoutNatureNobel
Domainal evolution of a prokaryotic DNA repair protein and its relationship to active-transport proteins
1986 StandoutNatureNobel
Biological and biochemical consequences of the human ERCC-1 repair gene after transfection into a repair-deficient CHO cell line
1987
The Yeast TFB1 and SSL1 Genes, Which Encode Subunits of Transcription Factor IIH, Are Required for Nucleotide Excision Repair and RNA Polymerase II Transcription
1995 StandoutNobel
Structural Relationship of Bacterial RecA Proteins to Recombination Proteins from Bacteriophage T4 and Yeast
1993 StandoutScienceNobel
Yeast Nucleotide Excision Repair Proteins Rad2 and Rad4 Interact with RNA Polymerase II Basal Transcription Factor b (TFIIH)
1994 StandoutNobel
Specific Cleavage of Model Recombination and Repair Intermediates by the Yeast Rad1-Rad10 DNA Endonuclease
1994 Science
Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II basal transcription factor b (TFIIH).
1994 StandoutNobel
Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.
1993
RAD1 and RAD10, but Not Other Excision Repair Genes, Are Required for Double-Strand Break-Induced Recombination in Saccharomyces cerevisiae
1995
Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- γc-/- mice: functional inactivation of p53 in developing T cells
2004
ERCC4 (XPF) Encodes a Human Nucleotide Excision Repair Protein with Eukaryotic Recombination Homologs
1996 StandoutNobel
Mechanisms Underlying Ubiquitination
2001 Standout
Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange.
1990
X-CHROMOSOME INACTIVATION IN MAMMALS
1997
Domains Required for Dimerization of Yeast Rad6 Ubiquitin-Conjugating Enzyme and Rad18 DNA Binding Protein
1997
Rec8p, a Meiotic Recombination and Sister Chromatid Cohesion Phosphoprotein of the Rad21p Family Conserved from Fission Yeast to Humans
1999
The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups A through I.
1989
Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins.
1994
UBIQUITIN AND THE CONTROL OF PROTEIN FATE IN THE SECRETORY AND ENDOCYTIC PATHWAYS
1998
Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells.
1988
Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia
2005
The ubiquitin-proteasome pathway: on protein death and cell life
1998 StandoutNobel
UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in Cockayne syndrome cells.
1996
bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog
1994
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53.
1994
The Saccharomyces cerevisiae DNA repair gene RAD25 is required for transcription by RNA polymerase II.
1993
Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3.
1994
Co-correction of the ERCC1, ERCC4 and xeroderma pigmentosum group F DNA repair defects in vitro.
1993
Nucleotide Sequence and Functional Analysis of the RAD1 Gene of Saccharomyces cerevisiae
1987
Influence of poly(ADP-ribose) polymerase on the enzymatic synthesis of SV40 DNA.
1991
Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae
1988
Cloning and characterization of a Saccharomyces cerevisiae gene encoding a new member of the ubiquitin-conjugating protein family
1991
Requirement for ERCC-1 and ERCC-3 gene products in DNA excision repair in vitro. Complementation using rodent and human cell extracts.
1992
DNA REPAIR GENES AND PROTEINS OF SACCHAROMYCES CEREVISIAE
1993
Human chromosome 15 confers partial complementation of phenotypes to xeroderma pigmentosum group F cells.
1989
Yeast RAD3 protein binds directly to both SSL2 and SSL1 proteins: implications for the structure and function of transcription/repair factor b.
1994 StandoutNobel
Human DNA Repair Genes
2001 StandoutScienceNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Correction of xeroderma pigmentosum complementation group D mutant cell phenotypes by chromosome and gene transfer: involvement of the human ERCC2 DNA repair gene.
1992
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Reconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP).
1995
THE RELATIVE CYTOTOXICITY OF(6–4) PHOTOPRODUCTS AND CYCLOBUTANE DIMERS IN MAMMALIAN CELLS*
1988
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Testis and somaticXrcc-1 DNA repair gene expression
1994
A human ubiquitin-conjugating enzyme homologous to yeast UBC8.
1994
Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.
1991 Standout
Yeast DNA-repair gene RAD14 encodes a zinc metalloprotein with affinity for ultraviolet-damaged DNA.
1993
Stable and Specific Association between the Yeast Recombination and DNA Repair Proteins RAD1 and RADIO In Vitro
1992
ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3.
1990
Molecular cloning of the human nucleotide-excision-repair gene ERCC4.
1994 StandoutNobel
A new nucleotide-excision-repair gene associated with the disorder trichothiodystrophy.
1993
Expression of Interleukin-10 Activity by Epstein-Barr Virus Protein BCRF1
1990 Science
UBA 1: an essential yeast gene encoding ubiquitin-activating enzyme.
1991
The Drosophila bendless gene encodes a neural protein related to ubiquitin-conjugating enzymes
1993
Works of Marcel Koken being referenced
Expression of the Ubiquitin-Conjugating DNA Repair Enzymes HHR6A and B Suggests a Role in Spermatogenesis and Chromatin Modification
1996
Inactivation of the HR6B Ubiquitin-Conjugating DNA Repair Enzyme in Mice Causes Male Sterility Associated with Chromatin Modification
1996
PML induces a novel caspase-independent death process
1998
PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3
2010
Genomic characterization of the human DNA excision repair geneERCC-1
1987
Cloning and characterization of theDrosophilahomolog of the xeroderma pigmentosum complementation-group B correcting gene,ERCC3
1992
Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24–q25 and 5q23–q31
1992
Postmeiotic Transcription of X and Y Chromosomal Genes during Spermatogenesis in the Mouse
1995
Hypoxia enhances human B19 erythrovirus gene expression in primary erythroid cells
2004
PML protein expression in hematopoietic and acute promyelocytic leukemia cells
1993
Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.
1991
Combined Arsenic and Retinoic Acid Treatment Enhances Differentiation and Apoptosis in Arsenic-Resistant NB4 Cells
1998
Serum-free medium for generation and propagation of functional human cytotoxic and helper T cell clones
1984
Arsenic-induced PML targeting onto nuclear bodies: Implications for the treatment of acute promyelocytic leukemia
1997
Role of Promyelocytic Leukemia (Pml) Sumolation in Nuclear Body Formation, 11s Proteasome Recruitment, and as2O3-Induced Pml or Pml/Retinoic Acid Receptor α Degradation
2001
The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA.
1990
Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.
1991
The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion.
1994
Leukemia-associated retinoic acid receptor α fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies
1997
Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor α (RAR α ) and oncogenic RAR α fusion proteins
1999
Molecular characterization of the human excision repair gene : cDNA cloning and amino acid homology with the yeast DNA repair gene
1986
Resistance to Virus Infection Conferred by the Interferon-Induced Promyelocytic Leukemia Protein
1998
RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability.
1992
The rhp6+ gene of Schizosaccharomyces pombe: a structural and functional homolog of the RAD6 gene from the distantly related yeast Saccharomyces cerevisiae.
1990
Induction of the PML protein by interferons in normal and APL cells.
1995