Marcel Koenig

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

Knock-in Mutation Reveals an Essential Role for Focal Adhesion Kinase Activity in Blood Vessel Morphogenesis and Cell Motility-Polarity but Not Cell Proliferation

AMPK: guardian of metabolism and mitochondrial homeostasis

ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression

Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks

The molecular machinery of regulated cell death

Entosis: The emerging face of non-cell-autonomous type IV programmed death

Small-molecule Mcl-1 inhibitors: Emerging anti-tumor agents

The JAK/STAT signaling pathway: from bench to clinic

c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges

Targeting apoptosis in cancer therapy

Macrophages as regulators of tumour immunity and immunotherapy

FAK in cancer: mechanistic findings and clinical applications

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

Tumour-microenvironmental interactions: paths to progression and targets for treatment

Small molecule Mcl-1 inhibitors for the treatment of cancer

Matrix Rigidity Controls Endothelial Differentiation and Morphogenesis of Cardiac Precursors

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

SUCCESSFUL TREATMENT OF PROTEUS SEPTICÆMIA WITH A NEW DRUG, TRIMETHOPRIM

Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients

New dimension in therapeutic targeting of BCL-2 family proteins

Structural Isosteres of Phosphate Groups in the Protein Data Bank

JNK signaling in cancer cell survival

TRIMETHOPRIM, A SULPHONAMIDE POTENTIATOR

Biomedical Importance of Indoles

Analysis of nanoparticle delivery to tumours

Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States

Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) Inhibitors

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors

Characterization of Dasatinib and Its Structural Analogs as CYP3A4 Mechanism-Based Inactivators and the Proposed Bioactivation Pathways

Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors

Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker

THE ACTION OF CERTAIN ANTIBIOTICS AND ANTIBIOTIC COMBINATIONS AGAINST PROTEUS MIRABILIS WITH DEMONSTRATION OF IN VITRO SYNERGISM AND ANTAGONISM