Citation Impact
Citing Papers
Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
2012 Standout
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse
2011
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
2010
Autophagy Opposes p53-Mediated Tumor Barrier to Facilitate Tumorigenesis in a Model of PALB2 -Associated Hereditary Breast Cancer
2013
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Chapter 1 Regulation of HIV-1 Alternative RNA Splicing and Its Role in Virus Replication
2009
The DNA-damage response in human biology and disease
2009 StandoutNature
In silico tools for splicing defect prediction: a survey from the viewpoint of end users
2013
Pancreatic cancer
2004 Standout
Phosphorylation of ETS1 by Src Family Kinases Prevents Its Recognition by the COP1 Tumor Suppressor
2014 StandoutNobel
The emerging landscape of breast cancer susceptibility
2007
SIFT web server: predicting effects of amino acid substitutions on proteins
2012 Standout
Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
2009 Standout
Targeting hypoxia in cancer therapy
2011 Standout
Caenorhabditis elegans sqt‐3 mutants have mutations in the col‐1 collagen gene
1994
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway
2008
RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
2011
PALB2 mutations in European familial pancreatic cancer families
2010
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Thermal stability and folding of the collagen triple helix and the effects of mutations in osteogenesis imperfecta on the triple helix of type I collagen
1993
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
2015 Standout
Targeting RNA splicing for disease therapy
2013
UBE2W Interacts with FANCL and Regulates the Monoubiquitination of Fanconi Anemia Protein FANCD2
2011
A 5′ Splice Site Enhances the Recruitment of Basal Transcription Initiation Factors In Vivo
2008
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
2008 Standout
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
1999 StandoutNobel
Homologous recombination and its regulation
2012
FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex
2008
The hnRNP A1 protein regulates HIV-1 tat splicing via a novel intron silencer element
2001
Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene
1991 StandoutNature
Extracellular Proteins Needed for C. elegans Mechanosensation
1996 StandoutNobel
RAD51C Germline Mutations in Breast and Ovarian Cancer Cases from High-Risk Families
2011
A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells
2016 StandoutNobel
Fanconi Anemia Repair Pathway Dysfunction, a Potential Therapeutic Target in Lung Cancer
2014
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Transportin-SR2 Imports HIV into the Nucleus
2008
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates
2011 StandoutNobel
Intermediate states during mRNA–tRNA translocation
2012 StandoutNobel
The FANCM family of DNA helicases/translocases
2010
Spliceosomal snRNA modifications and their function
2010
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
BRCA1 and its toolbox for the maintenance of genome integrity
2009
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
2010
Exon-intron circular RNAs regulate transcription in the nucleus
2015 Standout
Nonaccidental Head Injury in Infants — The “Shaken-Baby Syndrome”
1998 Standout
Stalled Fork Rescue via Dormant Replication Origins in Unchallenged S Phase Promotes Proper Chromosome Segregation and Tumor Suppression
2011
Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids
2011
Cystic fibrosis genetics: from molecular understanding to clinical application
2014 Standout
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Susceptibility Pathways in Fanconi's Anemia and Breast Cancer
2010
Intrinsic disorder drives N-terminal ubiquitination by Ube2w
2014 StandoutNobel
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Collagens—structure, function, and biosynthesis
2003 Standout
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Brittle bones - fragile molecules: disorders of collagen gene structure and expression
1990
Inactivation of human immunodeficiency virus in vitro by gossypol
1989
Targeting autophagy in cancer
2017 Standout
Nascent-seq indicates widespread cotranscriptional pre-mRNA splicing in Drosophila
2011 StandoutNobel
Identification of the FANCI Protein, a Monoubiquitinated FANCD2 Paralog Required for DNA Repair
2007
Detection of hepatitis C virus-specific antigens in semen from non-A, non-B hepatitis patients
1992
The ubiquitous role of ubiquitin in the DNA damage response
2010
SF2/ASF binds to a splicing enhancer in the third HIV-1 tat exon and stimulates U2AF binding independently of the RS domain
2001
COPII and the regulation of protein sorting in mammals
2011 StandoutNobel
Cellular mechanisms and physiological consequences of redox-dependent signalling
2014 Standout
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
An Alternative Form of Replication Protein A Expressed in Normal Human Tissues Supports DNA Repair
2009 StandoutNobel
Deubiquitinases as a Signaling Target of Oxidative Stress
2012
Ten Genes for Inherited Breast Cancer
2007
SEC23-SEC31 the Interface Plays Critical Role for Export of Procollagen from the Endoplasmic Reticulum
2012 StandoutNobel
Genome editing with engineered zinc finger nucleases
2010 Standout
Pancreatic cancer
2011 Standout
Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI
2008
Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products
2010 Standout
Type I procollagens containing substitutions of aspartate, arginine, and cysteine for glycine in the pro alpha 1 (I) chain are cleaved slowly by N-proteinase, but only the cysteine substitution introduces a kink in the molecule.
1992
A substitution of cysteine for glycine 748 of the alpha 1 chain produces a kink at this site in the procollagen I molecule and an altered N-proteinase cleavage site over 225 nm away.
1988
Cell cycle–dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24
2008
DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair
2007
Mechanism of Eukaryotic Homologous Recombination
2008
How the Fanconi Anemia Pathway Guards the Genome
2009
PALB2 Interacts with KEAP1 To Promote NRF2 Nuclear Accumulation and Function
2012
The ubiquitin landscape at DNA double-strand breaks
2009
Peptide immunogen mimicry of putative E1 glycoprotein-specific epitopes in hepatitis C virus
1994 StandoutNobel
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
2012 Standout
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
Distinct biochemical phenotypes predict clinical severity in nonlethal variants of osteogenesis imperfecta.
1990
The Origins of Medulloblastoma Subtypes
2008
FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair
2010 Science
A Targeted Bypass Screen Identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for Stable U1 snRNP/Pre-mRNA Interaction
2009 StandoutNobel
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies
2016 StandoutNobel
Circadian Clock, Cancer, and Chemotherapy
2014 StandoutNobel
Structural and Functional Relationships of the XPF/MUS81 Family of Proteins
2008
The Ubiquitin Code
2012 Standout
Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway
2011 Science
A new nuclease member of the FAN club
2010
Mechanisms of Alternative Pre-Messenger RNA Splicing
2003 Standout
Utility of DNA Repair Protein Foci for the Detection of Putative BRCA1 Pathway Defects in Breast Cancer Biopsies
2009
Crystal and Molecular Structure of a Collagen-Like Peptide at 1.9 Å Resolution
1994 StandoutScience
Works of Marcel Freund being referenced
Mutation of the RAD51C gene in a Fanconi anemia–like disorder
2010
A novel approach to describe a U1 snRNA binding site
2003
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer
2006
Correct mRNA Processing at a Mutant TT Splice Donor in FANCC Ameliorates the Clinical Phenotype in Patients and Is Enhanced by Delivery of Suppressor U1 snRNAs
2010
The sequence complementarity between HIV-1 5′ splice site SD4 and U1 snRNA determines the steady-state level of an unstable env pre-mRNA
2001
FANCI is a second monoubiquitinated member of the Fanconi anemia pathway
2007
Extended base pair complementarity between U1 snRNA and the 5' splice site does not inhibit splicing in higher eukaryotes, but rather increases 5' splice site recognition
2005
Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg−/− mice in vivo
2009
A Bidirectional SF2/ASF- and SRp40-Dependent Splicing Enhancer Regulates Human Immunodeficiency Virus Type 1 rev , env , vpu , and nef Gene Expression
2004
A point mutation in a type I procollagen gene converts glycine 748 of the alpha 1 chain to cysteine and destabilizes the triple helix in a lethal variant of osteogenesis imperfecta.
1987
Interaction of human immunodeficiency virus with human sperm in vitro.
1988