Citation Impact
Citing Papers
Monofunctional Platinum–DNA Adducts Are Strong Inhibitors of Transcription and Substrates for Nucleotide Excision Repair in Live Mammalian Cells
2011
Circadian oscillation of nucleotide excision repair in mammalian brain
2009 StandoutNobel
X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct
2010
The Thermodynamic Basis of the Stability of Proteins, Nucleic Acids, and Membranes
1976
Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA
1995 StandoutNatureNobel
Platinum(II) complexes containing iminoethers: a trans platinum antitumour agent
1995
Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine·guanine base pairs
1987 StandoutNobel
DNA unwinding produced by site-specific intrastrand crosslinks of the antitumor drug cis-diamminedichloroplatinum(II)
1991
Cisplatin inhibits synthesis of ribosomal RNA in vivo
1998
Inhibition of transcription by platinum antitumor compounds
2009
Thermodynamic and spectroscopic study of bulge loops in oligoribonucleotides
1990
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
Circular dichroism study of the irreversibility of conformational changes induced by polyamine-linked dinuclear platinum compounds
2002
Cisplatin: From DNA damage to cancer chemotherapy
2001
Peptide Nucleic Acid Pt(II) Conjugates: A Preliminary Study of Antisense Effects inXenopus laevis
2011
Self-Assembling Drugs: A New Approach to Biochemical Modulation in Cancer Chemotherapy
1994
Specificity of platinum–DNA adduct repair
1999
Cisplatin resistance in human cancers
1991
Ap endonucleases and dna glycosylases that recognize oxidative dna damage
1988
Repair synthesis by human cell extracts in DNA damaged bycis- andtrans-diamminedichloroplatinum(II)
1989
Crystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: Hydration at the platinated site
1999
Overexpression, purification, DNA binding, and dimerization of the Escherichia coli uvrD gene product (Helicase II)
1993
A conserved secondary structure for telomerase RNA
1991 StandoutNobel
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
A Photoactivated trans‐Diammine Platinum Complex as Cytotoxic as Cisplatin
2006
Effect of the diaminocyclohexane carrier ligand on platinum adduct formation, repair, and lethality
1990 StandoutNobel
The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes
1987
Mechanism of transcriptional stalling at cisplatin-damaged DNA
2007
HMG1 and 2, and related ‘architectural’ DNA-binding proteins
2001
DNA damage recognition during nucleotide excision repair in mammalian cells
1999
The Antitumor Agent Cisplatin Inhibits DNA Gyrase and Preferentially Induces gyrB Gene Expression inEscherichia coli
1996
Platinum complexes with imino ethers or cyclic ligands mimicking imino ethers: synthesis, in vitro antitumour activity, and DNA interaction properties
2004
Structural studies of interactions between anticancer platinum drugs and DNA
1996
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast
1994 StandoutNatureNobel
DNA Modifications by antitumor platinum and ruthenium compounds: Their recognition and repair
2002
Nonclassical Platinum Antitumor Agents: Perspectives for Design and Development of New Drugs Complementary to Cisplatin
1993
Cellular and molecular determinants of cisplatin resistance
1998
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
DNA Modifications by Antitumortrans-[PtCl2(E-Iminoether)2]
1997
NMR Solution Structure of a DNA Decamer Containing an Interstrand Cross-link of the Antitumor Drugcis-diamminedichloroplatinum(II)
1996
DNA adducts of antitumor trans-[PtCl2 (E-imino ether)2]
1996
Molecular mechanisms involved in cisplatin cytotoxicity
2000
A d(GpG)‐platinated decanucleotide duplex is kinked
1990
Use of single-turnover kinetics to study bulky adduct bypass by T7 DNA polymerase
1994
Sequence-dependent conformational changes in DNA induced by polynuclear platinum complexes
1999
Structural studies of atom-specific anticancer drugs acting on DNA
1999
Recognition of cisplatin adducts by cellular proteins
2001
Accuracy of wheat‐germ RNA polymerase II
1992
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Sequence Specificity of DNA-DNA Interstrand Cross-Link Formation by Cisplatin and Dinuclear Platinum Complexes
1994
DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand
2003
Superhelical torsion controls DNA interstrand cross-linking by antitumor cis- diamminedichloroplatinum(II)
1996
Sequence- and Region-Specificity of Oxaliplatin Adducts in Naked and Cellular DNA
1998
Repair of DNA interstrand cross-links
2001
Towards Antitumor Active trans‐Platinum Compounds
2009
Bending studies of DNA site-specifically modified by cisplatin, trans-diamminedichloroplatinum(II) and cis-[Pt(NH3) 2 (N3-cytosine) Cl]+
1990
Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonleaving groups
2000
Interaction of an N-methylated polyamine analogue, hexamethonium(2+), with sodium-DNA: quantitative nitrogen-14 and sodium-23 NMR relaxation rate studies of the cation-exchange process
1988
Local Supercoil-Stabilized DNA Structure
1991
Electron Crystal Structure of an RNA Polymerase II Transcription Elongation Complex
1999 StandoutNobel
DNA-protein cross-linking by trans-[PtCl2(E-iminoether)2]. A concept for activation of the trans geometry in platinum antitumor complexes
2003
Mechanism of Tracking and Cleavage of Adduct-damaged DNA Substrates by the Mammalian 5′- to 3′-Exonuclease/Endonuclease RAD2 Homologue 1 or Flap Endonuclease 1
1996
Recognition of DNA Adducts by Human Nucleotide Excision Repair
1996
Synthesis, characterization and antiproliferative studies of the enantiomers of cis-[(1,2-camphordiamine)dichloro]platinum(II) complexes
2007
Mechanisms of resistance to cisplatin
2001
A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA
1995
Current status of the development of trans-platinum antitumor drugs
2000
Polynucleotides. 8. A spectral approach to the equilibria between polyriboadenylate and polyribouridylate and their complexes.
1967
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
Antibodies specific for left-handed Z-DNA.
1981
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
A fluorescent complex between ethidium bromide and nucleic acids
1967 Standout
Monofunctional and Higher-Valent Platinum Anticancer Agents
2013
DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions.
1993 StandoutNobel
Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing
1996 StandoutScienceNobel
Novel folded protein domains generated by combinatorial shuffling of polypeptide segments
2000 StandoutNobel
Alteration of polynucleotide secondary structure by ribosomal protein S1.
1976
On the interaction of caffeine with nucleic acids
1980
Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites.
1990
Investigation of complexes formed between gene 32 protein from bacteriophage T4 and heavy-atom-modified single-stranded polynucleotides using optical detection of magnetic resonance
1986
Quality Control by DNA Repair
1999 StandoutScienceNobel
TATA Binding Protein Discriminates between Different Lesions on DNA, Resulting in a Transcription Decrease
1998
Nucleotide Sequence from the Coat Protein Cistron of R17 Bacteriophage RNA
1969 StandoutNatureNobel
Immunochemical quantitation of adducts induced in DNA by cis-diamminedichloroplatinum(II) and analysis of adduct-related DNA-unwinding
1985
Mechanistic studies of a novel class of trisubstituted platinum(II) antitumor agents.
1991
The Solution Structure of a DNA Duplex Containing the cis ‐Pt(NH3)2[d(‐GTG‐)‐N 7(G), N 7(G)] Adduct, as Determined with High‐Field NMR and Molecular Mechanics/Dynamics
1994
Additions to Metal-Activated Organonitriles
2002 Standout
BASIC MECHANISMS OF TRANSCRIPT ELONGATION AND ITS REGULATION
1997
2.4 Å Crystal Structure of an Oxaliplatin 1,2-d(GpG) Intrastrand Cross-Link in a DNA Dodecamer Duplex
2001
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair
2001 StandoutNobel
Reactivity of monofunctional cis-platinum adducts as a function of DNA sequence.
1988
An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts.
1992
Mechanistic Insight into the Inhibition of Matrix Metalloproteinases by Platinum Substrates
2009
Electron microscopy of DNA crosslinked with trimethylpsoralen: a probe for chromatin structure
1977 StandoutNobel
Molecular mechanisms of DNA repair inhibition by caffeine.
1990 StandoutNobel
Chromatin structure of the ribosomal RNA genes of Tetrahymena thermophila as analyzed by trimethylpsoralen crosslinking in vivo
1980 StandoutNobel
Effect of DNA Polymerases and High Mobility Group Protein 1 on the Carrier Ligand Specificity for Translesion Synthesis past Platinum−DNA Adducts
1999
An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication
1972 StandoutNobel
Conditions which cause the right-handed to left-handed DNA conformational transitions. Evidence for several types of left-handed DNA structures in solution.
1982
Atomic Structure of the DNA Repair [4Fe-4S] Enzyme Endonuclease III
1992 Science
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Direct observation of the torsional dynamics of DNA and RNA by picosecond spectroscopy.
1980 StandoutNobel
Visualizing tmRNA Entry into a Stalled Ribosome
2003 StandoutScienceNobel
Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena.
1981 StandoutNobel
Energetic coupling between DNA bending and base pair opening.
1988
Relaxation kinetics of dimer formation by self complementary oligonucleotides
1971
Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity
1974 StandoutNobel
A Monofunctional Platinum Complex Coordinated to a Rhodium Metalloinsertor Selectively Binds Mismatched DNA in the Minor Groove
2015
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
1999 Standout
Synthesis and DNA Interaction of Platinum Complex/Peptide Chimera as Potential Drug Candidates
2010
Transformations and recognition of platinum-DNA adducts: recent developments
1997
Assembly, subunit composition, and footprint of human DNA repair excision nuclease
1998 StandoutNobel
Protein Control of Redox Potentials of Iron−Sulfur Proteins
1996 StandoutNobel
Left-handed Z-DNA in bands of acid-fixed polytene chromosomes.
1983 StandoutNobel
DNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residues.
1993
Studies on the Formation of Transfer Ribonucleic Acid-Ribosome Complexes
1969
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei.
1976 StandoutNobel
Analysis of DNA of isolated chromatin subunits.
1975 StandoutNobel
Cisplatin inhibits chromatin remodeling, transcription factor binding, and transcription from the mouse mammary tumor virus promoter in vivo.
1995
Conformational differences between the biologically active and inactive forms of a transfer ribonucleic acid.
1967 StandoutNobel
Redox State-Dependent Interaction of HMGB1 and Cisplatin-Modified DNA
2011
HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.
1994 StandoutNobel
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
1997 StandoutNobel
The process of mRNA–tRNA translocation
2007 StandoutNobel
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro
2002
Quantum Mechanical Continuum Solvation Models
2005 Standout
Direct Cellular Responses to Platinum-Induced DNA Damage
2007
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Mechanistic Studies on Synthetic Fe−S-Based Clusters and Their Relevance to the Action of Nitrogenases
2005 StandoutNobel
Right-handed and left-handed DNA: studies of B- and Z-DNA by using proton nuclear Overhauser effect and P NMR.
1982
Variation of the supercoils in closed circular DNA by binding of antibiotics and drugs: Evidence for molecular models involving intercalation
1970
Adenylate oligomers in single- and double-strand conformation
1966
Noncytopathic Sindbis virus RNA vectors for heterologous gene expression
1998 StandoutNobel
Structure of the globin genes in chromatin
1975 StandoutNobel
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
RNA structure
1977
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
1997 StandoutScienceNobel
Synthesis and in Vitro Antitumor Activity of Platinum Acetonimine Complexes
2006
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.
1992 StandoutNobel
Works of Marc Leng being referenced
Sequence-dependent distortions induced in DNA by monofunctional platinum(II) binding
1992
Domain–domain interactions in high mobility group 1 protein (HMG1)
1999
Intrastrand cross-links are not formed in the reaction between transplatin and native DNA: relationm with the clinical inefficency of transplatin
1995
Formation of a DNA monofunctionalcis-platinum adduct cross-linking the intercalating drug N-methyl-2, 7-diazapyrenium
1990
Interstrand cross-links of cisplatin induce striking distortions in DNA
1999
HMG1 protein inhibits the translesion synthesis of the major DNA cisplatin adduct by cell extracts 1 1Edited by M. Yaniv
1997
DNA conformational change produced by the site-specific interstrand cross-link of trans-diamminedichloroplatinum(II)
1993
Reaction of nucleic acids with cis-diamminedichloroplatinum(II): interstrand cross-links
1987
Apoptosis Induction and DNA Interstrand Cross-Link Formation by Cytotoxictrans-[PtCl2(NH(CH3)2)(NHCH(CH3)2)]: Cross-Linking between d(G) and Complementary d(C) within Oligonucleotide Duplexes
2002
RNA polymerases react differently at d(ApG) and d(GpG) adducts in DNA modified by cis-diamminedichloroplatinum(II)
1992
Comparison Between poly(dG-dC)·poly(dG-dC) and DNA Modified by cis-diamminedichloroplatinum (II): Immunological and Spectroscopic Studies
1985
Chloroacetaldehyde reacts with Z-DNA
1988
Detection of minor adducts in cisplatin‐modified DNA by transcription footprinting
1993
Instability of the monofunctional adducts incis-[Pt(NH3)2(N7-N-methyl-2-diazapyrenium)CI]2+;-modified DNA: rates of cross-linking reactions incis-platinummodified DNA
1993
The DNA bending by acetylaminofluorene residues and by apurinic sites
1989
Chemical probes of the conformation of DNA modified by cis-diamminedichloroplatinum(II)
1989
In vitro and in vivo antitumour activity and cellular pharmacological properties of new platinum–iminoether complexes with different configuration at the iminoether ligands
1999
Transcription by eukaryotic and prokaryotic RNA polymerases of DNA modified at a d(GG) or a d(AG) site by the antitumor drug cis-diamminedichloroplatinum(II)
1991
Distortions induced in DNA by cis-platinum interstrand adducts
1992
Replacement of an NH3by an Iminoether in Transplatin Makes an Antitumor Drug from an Inactive Compound
2000
DNA bending induced by covalently bound drugs
1990
Base sequence-independent distortions induced by interstrand cross-links incis-diamminedichloroplatinum (ll)-modified DNA
1994
Conformation of DNA modified at a d(GG) or a d(AG) site by the antitumor drug cis-diamminedichloroplatinum(II)
1989
Spectrum of DNA-platinum adduct recognition by prokaryotic and eukaryotic DNA-dependent RNA polymerases
1993
Biophysical analysis of DNA modified by 1,2-diaminocyclohexane platinum(II) complexes
1992
Antiserum to Z‐DNA
1981
Immunological detection of lesions in DNA
1985
DNA adducts of cisplatin, transplatin and platinum-intercalating drugs.
1994
Conformational changes of poly(dG-dC). poly(dG-dC) modified by the carcinogen N-acetoxy-N-acetyl-2-aminofluorene
1981
A study of polyadenylic acid at neutral pH
1966
Transplatin-Modified Oligo(2‘-O-methyl ribonucleotide)s: A New Tool for Selective Modulation of Gene Expression
1997
Ring-opened alkylated guanine is not repaired in Z-DNA
1984 Nature
The B→Z transition of poly (dG–dC).poly(dG–dC) modified by some platinum derivatives
1981
Characterization of the ternary complexes formed in the reaction of cis-diamminedichloro platinum (II), ethidium bromide and nucleic acids
1987
Interaction between proflavine and double stranded polynucleotides
1974
Further studies on the interaction between polynucleotides and antibodies to poly(inosinic acid)·poly(cytidylic acid)
1978
Chemical Versatility of Transplatin Monofunctional Adducts within Multiple Site-Specifically Platinated DNA
1997
Left-handed Z-DNA
1985
Deoxyribonucleic acid-polylysine complexes. Structure and nucleotide specificity
1969
Immunological end spectroscopic studies of poly(dG-dC).poly(dG-dC) modified by cis-diamminedicholoroplatinum(II)
1984
Salt-dependent dynamic structure of poly(dG-dC) · poly(dG-dC)
1980 Nature
Discrimination by antibodies between local defects in DNA induced by 2‐aminofluorene derivatives
1979
Immunochemical studies of DNA modified by cis-dichlorodiammineplatinum(II) in vivo and in vitro.
1981
Interaction of spermine and DNA
1967
Sodium cyanide: a chemical probe of the conformation of DNA modified by the antitumor drug cis-diamminedichloroplatinum(II)
1990
Interaction between antibodies to Z-form deoxyribonucleic acid and double-stranded polynucleotides
1982
Poly(dA-dT).cntdot.poly(dA-dT) two-pathway proton exchange mechanism. Effect of general and specific base catalysis on deuteration rates
1986