Citation Impact
Citing Papers
Non-Identity-Mediated CRISPR-Bacteriophage Interaction Mediated via the Csy and Cas3 Proteins
2011
Probing Gene Expression in Live Cells, One Protein Molecule at a Time
2006 Science
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70 S Ribosome
2009 StandoutScienceNobel
Structure of the 70 S Ribosome Complexed with mRNA and tRNA
2006 StandoutScienceNobel
De novo design of self-assembling helical protein filaments
2018 StandoutScienceNobel
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
Counting Low-Copy Number Proteins in a Single Cell
2007 StandoutScienceNobel
From molecular to modular cell biology
1999 StandoutNatureNobel
MicroRNAs
2004 Standout
Bypassing of stems versus linear base‐by‐base inspection of mammalian mRNAs during ribosomal scanning
2010
The Transition to an Elongation Complex by T7 RNA Polymerase Is a Multistep Process
2007
Overexpression of a DEAD Box Protein (DDX1) in Neuroblastoma and Retinoblastoma Cell Lines
1998
Kinetic Checkpoint at a Late Step in Translation Initiation
2008
Over-production of Proteins inEscherichia coli: Mutant Hosts that Allow Synthesis of some Membrane Proteins and Globular Proteins at High Levels
1996 StandoutNobel
Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences
2008 Standout
Early Formation of mRNP
2003 StandoutNobel
A structural view of translation initiation in bacteria
2008
Characterization of structural features important for T7 RNAP elongation complex stability reveals competing complex conformations and a role for the non-template strand in RNA displacement
1999
Characterization of halted T7 RNA polymerase elongation complexes reveals multiple factors that contribute to stability 1 1Edited by M. Gottesman
2000
Structural changes in glycogen phosphorylase induced by phosphorylation
1988 Nature
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Principles for designing ideal protein structures
2012 StandoutNatureNobel
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Stochastic protein expression in individual cells at the single molecule level
2006 Nature
Nonbridging phosphate oxygens in 16S rRNA important for 30S subunit assembly and association with the 50S ribosomal subunit
2005
Transcription Initiation in a Single-Subunit RNA Polymerase Proceeds through DNA Scrunching and Rotation of the N-Terminal Subdomains
2008
Initiation of mRNA translation in prokaryotes
1990
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
2001 StandoutNobel
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Three-dimensional structure of Escherichia coli RNA polymerase holoenzyme determined by electron crystallography
1989 StandoutNatureNobel
Major Conformational Changes During T7RNAP Transcription Initiation Coincide with, and are Required for, Promoter Release
2005
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
RNA helicases — one fold for many functions
2007
Mechanisms by which T7 lysozyme specifically regulates T7 RNA polymerase during different phases of transcription 1 1Edited by R. Ebright
1999
Unusual mRNA pseudoknot structure is recognized by a protein translational repressor
1989
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
2011 StandoutNatureNobel
Circuit Simulation of Genetic Networks
1995 Science
The allosteric transition of glycogen phosphorylase
1989 Nature
T7 RNA polymerase elongation complex structure and movement
2000
Crystal structure of a hepatitis delta virus ribozyme
1998 StandoutNatureNobel
The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase
2004 StandoutNobel
Mutations that alter the ability of theEscherichia colicyclic AMP receptor protein to activate transcription
1990
The Definition of Generalized Helicoidal Parameters and of Axis Curvature for Irregular Nucleic Acids
1988
Protocols for Implementing an <em>Escherichia coli</em> Based TX-TL Cell-Free Expression System for Synthetic Biology
2013
Activation of C. elegans cell death protein CED-9 by an ammo-acid substitution in a domain conserved in Bcl-2
1994 StandoutNatureNobel
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Exploitation of binding energy for catalysis and design
2009 StandoutNatureNobel
The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation
2008 StandoutScienceNobel
B-Cell Control Region at the 5′ End of a Major Histocompatibility Complex Class II Gene: Sequences and Factors
1988
Efficient splicing of two yeast mitochondrial introns controlled by a nuclear-encoded maturase.
1987
On the different binding affinities of CRP at thelac, galandmalT promoter regions
1983
On the action of the cyclic AMP-cyclic AMP receptor protein complex at the Escherichia coli lactose and galactose promoter regions.
1984
Altering the Genome by Homologous Recombination
1989 StandoutScienceNobel
Cyclic AMP Receptor Protein: Role in Transcription Activation
1984 Science
Cutting Edge: Innate Immune System Discriminates between RNA Containing Bacterial versus Eukaryotic Structural Features That Prime for High-Level IL-12 Secretion by Dendritic Cells
2004 StandoutNobel
Evolutionary Conservation of Reactions in Translation
2002
Unusual properties of promoter-up mutations in the Escherichia coli galactose operon and evidence suggesting RNA polymerase-induced DNA bending.
1987
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Crystal Structure of an Initiation Factor Bound to the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
High level of accumulation of a mRNA coding for a precursor-like protein in the submaxillary gland of male rats.
1988
Coupling of Tetrahymena Ribosomal RNA Splicing to β-Galactosidase Expression in Escherichia coli
1985 StandoutScienceNobel
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
The Oct-2 protein binds cooperatively to adjacent octamer sites.
1989
Oct-4: a germline-specific transcription factor mapping to the mouse t-complex.
1990
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
Role of alpha-fetoprotein regulatory elements in transcriptional activation in transient heterokaryons.
1990
Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma.
1988
Processing of yeast mitochondrial RNA: Involvement of intramolecular hybrids in splicing of cob intron 4 RNA by mutation and reversion
1983
The Molecular Mechanics of Eukaryotic Translation
2004
The binding of the cyclic AMP receptor protein to synthetic DNA sites containing permutations in the consensus sequence TGTGA
1987
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
Maturation of the 5′ end of Bacillus subtilis 16S rRNA by the essential ribonuclease YkqC/RNase J1
2006
Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems
1999
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
Two intron sequences in yeast mitochondrial COX1 gene: Homology among URF-containing introns and strain-dependent variation in flanking exons
1983
POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter.
1991
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Intrinsic noise in gene regulatory networks
2001
Stochastic Kinetic Analysis of Developmental Pathway Bifurcation in Phage λ-Infected Escherichia coli Cells
1998
An intron-encoded protein is active in a gene conversion process that spreads an intron into a mitochondrial gene
1985
Self-cleaving transcripts of satellite DNA from the newt
1987
Protein production by auto-induction in high-density shaking cultures
2005 Standout
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
2002 StandoutScienceNobel
Stochastic mechanisms in gene expression
1997
POU-domain transcription factors: pou-er-ful developmental regulators.
1991
The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin
1988 Standout
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Self-splicing of group II introns in vitro: Mapping of the branch point and mutational inhibition of lariat formation
1986
Topology of Yeast RNA Polymerase II Subunits in Transcription Elongation Complexes Studied by Photoaffinity Cross-Linking
2000
Mechanism of recognition of the 5′ splice site in self-splicing group I introns
1986 StandoutNatureNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
The C-Terminal Region of Eukaryotic Translation Initiation Factor 3a (eIF3a) Promotes mRNA Recruitment, Scanning, and, Together with eIF3j and the eIF3b RNA Recognition Motif, Selection of AUG Start Codons
2010
Works of Marc Dreyfus being referenced
Role of Introns in the Yeast Cytochrome- b Gene: Cis - and Trans -acting Signals, Intron Manipulation, Expression, and Intergenic Communications
1982
The Poly(A) Tail of mRNAs
2002
The DEAD‐box RNA helicase SrmB is involved in the assembly of 50S ribosomal subunits in Escherichia coli
2003
DEAD-box RNA helicases in Escherichia coli
2006
The low processivity of T7 RNA polymerase over the initially transcribed sequence can limit productive initiation in vivo
1997
What constitutes the signal for the initiation of protein synthesis on Escherichia coli mRNAs?
1988
Troubleshooting coupled in vitro transcription–translation system derived from Escherichia coli cells: synthesis of high-yield fully active proteins
2006
Ded1p, a DEAD-box Protein Required for Translation Initiation in Saccharomyces cerevisiae, Is an RNA Helicase
1999
Studies on Three E. coli DEAD-Box Helicases Point to an Unwinding Mechanism Different from that of Model DNA Helicases
2004
Interdependence of translation, transcription and mRNA degradation in the lacZ gene
1992
NTP concentration effects on initial transcription by T7 RNAP indicate that translocation occurs through passive sliding and reveal that divergent promoters have distinct NTP concentration requirements for productive initiation 1 1Edited by R. Ebright
1998
On the mechanism of inhibition of phage T7 RNA polymerase by lac repressor 1 1Edited by R. Ebright
1998
Regulated expression of the Ren-2 gene in transgenic mice derived from parental strains carrying only the Ren-1 gene.
1987
Molecular orbital calculations on the conformation of polypeptides and proteins
1970
Transcribing of Escherichia coli genes with mutant T7 RNA polymerases: stability of lacZ mRNA inversely correlates with polymerase speed.
1995
A mutation in T7 RNA polymerase that facilitates promoter clearance
2005
The Highly Efficient Translation Initiation Region from the Escherichia coli rpsA Gene Lacks a Shine-Dalgarno Element
2006
Mechanism of allosteric activation of glycogen phosphorylase probed by the reactivity of essential arginyl residues. Physicochemical and kinetic studies
1980
Antibodies against synthetic oligopeptides allow identification of the mRNA-maturase encoded by the second intron of the yeast cob-box gene.
1984
AU-Rich Sequences within 5′ Untranslated Leaders Enhance Translation and Stabilize mRNA in Escherichia coli
2005
mRNAs can be stabilized by DEAD-box proteins
1994 Nature
The conserved decanucleotide from the immunoglobulin heavy chain promoter induces a very high transcriptional activity in B-cells when introduced into an heterologous promoter.
1987
The stability of Escherichia coli lacZ mRNA depends upon the simultaneity of its synthesis and translation.
1995
Segment-specific mutagenesis of the regulatory region in the Escherichia coli galactose operon: isolation of mutations reducing the initiation of transcription and translation
1983
Conformational changes and local events at the AMP site of glycogen phosphorylase b: a fluorescence temperature-jump relaxation study
1978
The selection and characterization of two novel mutations in the overlapping promoters of the Escherichia coli galactose operon
1984