Citation Impact
Citing Papers
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Microenvironmental modulation breaks intrinsic pH limitations of nanozymes to boost their activities
2024 StandoutNobel
Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. A literature survey
2008 Standout
Three-component coupling using arynes and DMF: straightforward access to coumarins via ortho-quinone methides
2011
Synthesis of quinolines via Friedländer reaction catalyzed by CuBTC metal–organic-framework
2012
Practical, Modular, and General Synthesis of 3‐Coumaranones through Gold‐Catalyzed Intermolecular Alkyne Oxidation Strategy
2014
QM/MM Methods for Biomolecular Systems
2009 Standout
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Modifying enzyme activity and selectivity by immobilization
2012 Standout
Interactions of AChE with A? Aggregates in Alzheimer?s Brain: Therapeutic Relevance of IDN 5706
2011
Heterogeneous Catalysis through Microcontact Printing
2008 StandoutNobel
Chemical kinetics for drug discovery to combat protein aggregation diseases
2014
Structure-Based Drug Design Strategies in Medicinal Chemistry
2009
Reaction site-driven regioselective synthesis of AChE inhibitors
2013
One-dimensional alignment of strong Lewis acid sites in a porous coordination polymer
2013 StandoutNobel
Molecular Dynamics Simulation for All
2018 Standout
Recent advances in transition-metal-free carbon–carbon and carbon–heteroatom bond-forming reactions using arynes
2012 Standout
Multi-Target Drugs: The Trend of Drug Research and Development
2012
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Acetylcholinesterase: ‘classical’ and ‘non-classical’ functions and pharmacology
2005
Organocatalytic asymmetric intramolecular [3+2] cycloaddition: A straightforward approach to access multiply substituted hexahydrochromeno[4,3-b]pyrrolidine derivatives in high optical purity
2010
Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer's disease
2011
Dual Inhibitors of β-Amyloid Aggregation and Acetylcholinesterase as Multi-Target Anti-Alzheimer Drug Candidates
2013
Design, synthesis, and evaluation of indanone derivatives as acetylcholinesterase inhibitors and metal-chelating agents
2012
Fragment-based lead discovery: a chemical update
2006
Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z
2010
Technological Advances in High-Throughput Screening
2004
Fluorescent indicators based on BODIPY
2011 Standout
Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure
2018 StandoutNobel
Continuous‐Flow Technology—A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients
2015 Standout
Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents
2012
Catalytic asymmetric synthesis of chromenes and tetrahydroquinolines via sequential allylic alkylation and intramolecular Heck coupling
2012 StandoutNobel
Bivalent Ligands Derived from Huperzine A as Acetylcholinesterase Inhibitors
2007
Beware of q2!
2002 Standout
An image analysis toolbox for high-throughput C. elegans assays
2012 StandoutNobel
Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation
2016
The amyloid state and its association with protein misfolding diseases
2014 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Triazole-containing BODIPY dyes as novel fluorescent probes for soluble oligomers of amyloid Aβ1–42 peptide
2009
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Intramolecular Dipolar Cycloaddition Reactions of Azomethine Ylides
2005
Diastereoselective Synthesis of Indanes via a Domino Stetter−Michael Reaction
2009
Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy
2012 Standout
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
2016 StandoutNobel
Computer Simulation of Liquids
2017 Standout
Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom
2011 Standout
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Unsaturated Lactams: New Inputs for Povarov-Type Multicomponent Reactions
2010
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
2009 Standout
Synthesis and Biological Evaluation of Bisindenoisoquinolines as Topoisomerase I Inhibitors
2006
Bright Side of Lignin Depolymerization: Toward New Platform Chemicals
2018 Standout
Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade
2018
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Electronic-State Switching Strategy in the Photochemical Synthesis of Indanones from o-Methyl Phenacyl Epoxides
2011
Electrophilic Cyclization of 2-Chalcogenealkynylanisoles: Versatile Access to 2-Chalcogen-benzo[b]furans
2009
Glyoxyl agarose: A fully inert and hydrophilic support for immobilization and high stabilization of proteins
2005
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy
2010
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
A Scalable Procedure for Light-Induced Benzylic Brominations in Continuous Flow
2013
Applications of metal–organic frameworks in heterogeneous supramolecular catalysis
2014 Standout
Metadynamics: a method to simulate rare events and reconstruct the free energy in biophysics, chemistry and material science
2008
Hydrogen Autotransfer in the N-Alkylation of Amines and Related Compounds using Alcohols and Amines as Electrophiles
2009 Standout
Acetylcholinesterase Inhibitors with Photoswitchable Inhibition of β-Amyloid Aggregation
2014
Acetylcholinesterase: Mechanisms of Covalent Inhibition of Wild-Type and H447I Mutant Determined by Computational Analyses
2007
Determination of Diazepam, Temazepam and Oxazepam at the Lead Film Electrode by Adsorptive Cathodic Stripping Voltammetry
2010
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
New Tacrine–4-Oxo-4H-chromene Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease, with Cholinergic, Antioxidant, and β-Amyloid-Reducing Properties
2012
Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes
2015 Standout
Functionalization of Micelles and Shell Cross-linked Nanoparticles Using Click Chemistry
2005
On the lag phase in amyloid fibril formation
2015
Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods
2019 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Shell Click-Crosslinked (SCC) Nanoparticles: A New Methodology for Synthesis and Orthogonal Functionalization
2005
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Synthesis, biological evaluation and mechanism study of chalcone analogues as novel anti-cancer agents
2015
Construction of Enantiopure Pyrrolidine Ring System via Asymmetric [3+2]-Cycloaddition of Azomethine Ylides
2006 Standout
Highly Stereoselective Synthesis of 1,2,3-Trisubstituted Indanes via Oxidative N-Heterocyclic Carbene-Catalyzed Cascades
2011
Recent Advances in the Friedländer Reaction
2009
Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates
2014 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity
2009 Standout
Efficient Templated Synthesis of Donor−Acceptor Rotaxanes Using Click Chemistry
2006 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Comparison of drug sensitivity using acetylcholinesterase biosensor based on nanoparticles–chitosan sol–gel composite
2007
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
Synthesis of 2,5‐Diaminoquinones by One‐Pot Copper‐Catalyzed Aerobic Oxidation of Hydroquinones and Addition Reaction of Amines
2009
Works of Manuela Bartolini being referenced
Targeting Alzheimer’s disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238
2010
Insight Into the Kinetic of Amyloid β (1–42) Peptide Self‐Aggregation: Elucidation of Inhibitors’ Mechanism of Action
2007
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer’s disease
2011
Structure–Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo‐Irreversible Inhibitors Related to Xanthostigmine
2009
Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers
2011
β-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies
2003
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors
2008
2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents
2012
The role of Li+, Na+, and K+ in the ligand binding inside the human acetylcholinesterase gorge
2007
Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds
2007
A Small Molecule Targeting the Multifactorial Nature of Alzheimer's Disease
2007
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment
2011
Strategies for the Inhibition of Protein Aggregation in Human Diseases
2010
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity
2010
Analytical methods for the determination of folic acid in a polymeric micellar carrier
2003
Chemical and Pharmacological Studies on Enantiomerically Pure p‐Methoxytacripyrines, Promising Multi‐Target‐Directed Ligands for the Treatment of Alzheimer’s Disease
2011
Bis(7)‐tacrine Derivatives as Multitarget‐Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities
2010
Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation
2011
Drug affinity to immobilized target bio-polymers by high-performance liquid chromatography and capillary electrophoresis
2003
Development and characterization of an immobilized enzyme reactor based on glyceraldehyde-3-phosphate dehydrogenase for on-line enzymatic studies
2003
Hexahydrochromeno[4,3-b]pyrrole Derivatives as Acetylcholinesterase Inhibitors
2000
Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer’s Disease
2007
Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds
2009
Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents
2014
Novel 8‐Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer′s Disease
2016
SAR of 9-Amino-1,2,3,4-tetrahydroacridine-Based Acetylcholinesterase Inhibitors: Synthesis, Enzyme Inhibitory Activity, QSAR, and Structure-Based CoMFA of Tacrine Analogues
2000
Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[ω-(benzylmethylamino)alkoxy]xanthen-9-ones
2006
Choosing the right chromatographic support in making a new acetylcholinesterase-micro-immobilised enzyme reactor for drug discovery
2004
Novel Donepezil-Based Inhibitors of Acetyl- and Butyrylcholinesterase and Acetylcholinesterase-Induced β-Amyloid Aggregation
2008
Nature‐Inspired Multifunctional Ligands: Focusing on Amyloid‐Based Molecular Mechanisms of Alzheimer's Disease
2015
Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects
2014
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease
2007
Structure−Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Further Investigation on the Inner Spacer
2008
Toward a Rational Design of Multitarget-Directed Antioxidants: Merging Memoquin and Lipoic Acid Molecular Frameworks
2009
Propidium-Based Polyamine Ligands as Potent Inhibitors of Acetylcholinesterase and Acetylcholinesterase-Induced Amyloid-β Aggregation
2004
Cholinesterase Inhibitors: Xanthostigmine Derivatives Blocking the Acetylcholinesterase-Induced β-Amyloid Aggregation
2005
Benzofuran-Based Hybrid Compounds for the Inhibition of Cholinesterase Activity, β Amyloid Aggregation, and Aβ Neurotoxicity
2008
Structure−Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 3. Effect of Replacing the Inner Polymethylene Chain with Cyclic Moieties
2004
Huprine–Tacrine Heterodimers as Anti-Amyloidogenic Compounds of Potential Interest against Alzheimer’s and Prion Diseases
2011
Synthesis of Monomeric Derivatives To Probe Memoquin’s Bivalent Interactions
2011
Structure–activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action
2009
3-(4-{[Benzyl(methyl)amino]methyl}phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) Inhibits Both Acetylcholinesterase and Acetylcholinesterase-Induced β-Amyloid Aggregation: A Dual Function Lead for Alzheimer's Disease Therapy
2003
A Small Molecule Targeting the Multifactorial Nature of Alzheimer's Disease
2007
Rational Approach To Discover Multipotent Anti-Alzheimer Drugs
2004
Novel Huprine Derivatives with Inhibitory Activity toward β‐Amyloid Aggregation and Formation as Disease‐Modifying Anti‐Alzheimer Drug Candidates
2010
Tacripyrines, the First Tacrine−Dihydropyridine Hybrids, as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease
2009
S4–04–04: Memoquin, a novel multifunctional compound for Alzheimer's disease: An up–date on preclinical studies
2006
Design, Synthesis, and Biological Evaluation of Conformationally Restricted Rivastigmine Analogues
2004
Design, Synthesis, and Biological Evaluation of Dual Binding Site Acetylcholinesterase Inhibitors: New Disease-Modifying Agents for Alzheimer's Disease
2005