Citation Impact
Citing Papers
Human Hypertension Caused by Mutations in WNK Kinases
2001 StandoutScience
Dynamic behavior of paired claudin strands within apposing plasma membranes
2003
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Deletion of claudin-10 ( Cldn10 ) in the thick ascending limb impairs paracellular sodium permeability and leads to hypermagnesemia and nephrocalcinosis
2012
Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules
2010
A Sulfilimine Bond Identified in Collagen IV
2009 StandoutScienceNobel
Tight Junction Proteins Claudin-2 and -12 Are Critical for Vitamin D-dependent Ca 2+ Absorption between Enterocytes
2008
Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions
2014 Science
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Claudin-8 Expression in Madin-Darby Canine Kidney Cells Augments the Paracellular Barrier to Cation Permeation
2003
A Novel Claudin 16 Mutation Associated with Childhood Hypercalciuria Abolishes Binding to ZO-1 and Results in Lysosomal Mistargeting
2003
Megaintestine in Claudin-15–Deficient Mice
2007
Kidney claudin‐19: Localization in distal tubules and collecting ducts and dysregulation in polycystic renal disease
2006
Acid-Base Status Determines the Renal Expression of Ca2+ and Mg2+ Transport Proteins
2006
Paracellular Ion Channel at the Tight Junction
2003
Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins
2006
Macrophage Inhibitory Factor, Plasminogen Activator Inhibitor-1, Other Acute Phase Proteins, and Inflammatory Mediators Normalize as a Result of Weight Loss in Morbidly Obese Subjects Treated with Gastric Restrictive Surgery
2004
Expression of Claudin-2 in intestinal metaplastic mucosa of Cdx2-transgenic mouse stomach
2010
The Epithelial Mg2+ Channel Transient Receptor Potential Melastatin 6 Is Regulated by Dietary Mg2+ Content and Estrogens
2006
Acute kidney injury
2012 Standout
Molecular genetics of human hypertension
1998
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
Tight Junctions: Molecular Architecture and Function
2006
Increased plasma metalloproteinase-9 concentrations precede development of microalbuminuria in non-insulin-dependent diabetes mellitus
1998
Regulation of the Expression of the Prostate-specific Antigen by Claudin-7
2003
Effect of the Angiotensin-Converting–Enzyme Inhibitor Benazepril on the Progression of Chronic Renal Insufficiency
1996 Standout
Ca2+-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions
1999
Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes
2016 Standout
A Deletion of the Paracellin-1 Gene Is Responsible for Renal Tubular Dysplasia in Cattle
2000
RENAL DISEASE ASSOCIATED WITH HEPATITIS C INFECTION AFTER KIDNEY AND LIVER TRANSPLANTATION1
2000
Claudins in occluding junctions of humans and flies
2006
Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes
2014 Standout
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Claudin-8 Expression in Renal Epithelial Cells Augments the Paracellular Barrier by Replacing Endogenous Claudin-2
2007
Management of Glomerular Proteinuria
2003
Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy
2001 Standout
WOUND-HEALING COMPLICATIONS AFTER KIDNEY TRANSPLANTATION: A PROSPECTIVE, RANDOMIZED COMPARISON OF SIROLIMUS AND TACROLIMUS1
2004
Interaction of hepatitis C virus NS5A with La protein revealed by T7 phage display
2003
Disease-associated mutations affect intracellular traffic and paracellular Mg2+ transport function of Claudin-16
2006
Association of Paracellin-1 with ZO-1 Augments the Reabsorption of Divalent Cations in Renal Epithelial Cells
2004
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure<SUBTITLE>The JNC 7 Report</SUBTITLE>
2003 Standout
The metabolic syndrome
2010 Standout
Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association
2019
Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes
2001 Standout
The Molecular Basis of Goodpasture and Alport Syndromes
2004
Multifunctional strands in tight junctions
2001 Standout
Function and regulation of claudins in the thick ascending limb of Henle
2008
Insights into Driving Forces and Paracellular Permeability from Claudin‐16 Knockdown Mouse
2009
Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement
2004
The Claudin-like Megatrachea Is Essential in Septate Junctions for the Epithelial Barrier Function in Drosophila
2003
Differential Expression Patterns of Claudins, Tight Junction Membrane Proteins, in Mouse Nephron Segments
2002
Altered expression of tight junction proteins in mammary epithelium after discontinued suckling in mice
2011
Extensive Expansion of the Claudin Gene Family in the Teleost Fish, Fugu rubripes
2004 Nobel
Tight junctions containing claudin 4 and 6 are essential for blastocyst formation in preimplantation mouse embryos
2007
Prevalence and Trends in Obesity Among US Adults, 1999-2008
2010 Standout
Inflammatory Bowel Disease
2009 Standout
Mutations in the Gene Encoding Tight Junction Claudin-14 Cause Autosomal Recessive Deafness DFNB29
2001
Claudin‐14 regulates renal Ca++ transport in response to CaSR signalling via a novel microRNA pathway
2012
European guidelines on cardiovascular disease prevention in clinical practice: Executive summary
2007
Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood–brain-barrier endothelial cells via protein kinase A-dependent and -independent pathways
2003
Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases
2020 Standout
Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia
2005
Drug-induced acute kidney injury in the critically ill adult: Recognition and prevention strategies
2010
Assessing Kidney Function — Measured and Estimated Glomerular Filtration Rate
2006 Standout
Tight junction proteins
2002
Activation of a polyvalent cation-sensing receptor decreases magnesium transport via claudin-16
2007
A New Equation to Estimate Glomerular Filtration Rate
2009 Standout
Follow-up of five patients with FHHNC due to mutations in the Paracellin-1 gene
2002
Setting up a selective barrier at the apical junction complex
2004
Differential expression of claudin tight junction proteins in the human cortical nephron
2010
CNNM2, Encoding a Basolateral Protein Required for Renal Mg2+ Handling, Is Mutated in Dominant Hypomagnesemia
2011
Chronic Renal Failure after Transplantation of a Nonrenal Organ
2003 Standout
Acute kidney injury
2019 Standout
The metabolic syndrome
2005 Standout
Structure and function of claudins
2007
Renal Dysplasia Unrelated to Claudin-16 Deficiency in Japanese Black Cattle
2007
Claudins of intestine and nephron – a correlation of molecular tight junction structure and barrier function
2010
Angiotensin-converting enzyme in non-neoplastic kidney diseases
1999
The claudin gene family: expression in normal and neoplastic tissues
2006
Intestinal mucosal barrier function in health and disease
2009 Standout
Regulation of magnesium homeostasis and transport in mammalian cells
2006
Claudins and Other Tight Junction Proteins
2012
The CLDN5 locus may be involved in the vulnerability to schizophrenia
2004
Renal function: the Cinderella of cardiovascular risk profile
2001
Mutation of the Mg2+ Transporter SLC41A1 Results in a Nephronophthisis-Like Phenotype
2013
Angiotensin-Converting Enzyme Inhibitors and Kidney Protection: The AIPRI Trial
1999
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
A missense mutation in the Kv1.1 voltage-gated potassium channel–encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia
2009
Salt and acid-base metabolism in claudin-16 knockdown mice: impact for the pathophysiology of FHHNC patients
2008
Multi-PDZ Domain Protein 1 (MUPP1) Is Concentrated at Tight Junctions through Its Possible Interaction with Claudin-1 and Junctional Adhesion Molecule
2002
Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut
2001
Identification and subcellular localization of paracellin-1 (claudin-16) in human salivary glands
2007
M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
2009 Standout
Reduced Exposure to Calcineurin Inhibitors in Renal Transplantation
2007 Standout
Proposed Pathogenesis of Idiopathic Loin Pain–Hematuria Syndrome
2006
Genetic control of single lumen formation in the zebrafish gut
2007
Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns
2006
Cardiorenal Syndrome Type 1
2012
Primary Gene Structure and Expression Studies of Rodent Paracellin-1
2001
Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells
2004
Differential expression of claudin‐2 along the human intestine: Implication of GATA‐4 in the maintenance of claudin‐2 in differentiating cells
2004
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: blocking endocytosis restores surface expression of a novel Claudin-16 mutant that lacks the entire C-terminal cytosolic tail
2006
Transgenic RNAi Depletion of Claudin-16 and the Renal Handling of Magnesium
2007
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine
2010
Thr207 of claudin-5 is involved in size-selective loosening of the endothelial barrier by cyclic AMP
2004
Exclusion of mutations in FXYD2, CLDN16 and SLC12A3 in two families with primary renal Mg2+ loss
2003
Epithelial Ca2+ and Mg2+ Channels in Health and Disease
2004
Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia
2002
Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
2013 Standout
Hepatitis C Virus Entry
2007 StandoutNobel
IFN-γ-Induced TNFR2 Expression Is Required for TNF-Dependent Intestinal Epithelial Barrier Dysfunction
2006
The Roles of Claudin Superfamily Proteins in Paracellular Transport
2001
Alport's Syndrome, Goodpasture's Syndrome, and Type IV Collagen
2003
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Extracellular Mg2+ regulates the tight junctional localization of claudin-16 mediated by ERK-dependent phosphorylation
2009
Increased expression of renal TRPM6 compensates for Mg2+ wasting during furosemide treatment
2012
Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration
2003
Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability
2001
Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland
2004
Effect of claudins 6 and 9 on paracellular permeability in MDCK II cells
2008
Double gene deletion reveals lack of cooperation between claudin 11 and claudin 14 tight junction proteins
2008
Transmembrane proteins of tight junctions
2007
Atherosclerosis
2000 StandoutNature
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
Hepatocyte nuclear factor (HNF)-4α triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells
2003
Claudin-16 and claudin-19 interact and form a cation-selective tight junction complex
2008
Differential Diagnosis of Glomerular Disease: A Systematic and Inclusive Approach
2013 Standout
The effect of RAAS blockade on the progression of diabetic nephropathy
2013
Renal localization and function of the tight junction protein, claudin-19
2007
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family
2002
The Effect of Angiotensin-Converting-Enzyme Inhibition on Diabetic Nephropathy
1993 Standout
Basolateral Mg2+ Extrusion via CNNM4 Mediates Transcellular Mg2+ Transport across Epithelia: A Mouse Model
2013
Claudin Function in the Thick Ascending Limb of Henle's Loop
2009
Expression patterns of claudins, tight junction adhesion molecules, in the inner ear
2003
Enhanced atherosclerosis and kidney dysfunction in eNOS–/–Apoe–/– mice are ameliorated by enalapril treatment
2000 StandoutNobel
Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium
2004
Two splice variants of claudin-10 in the kidney create paracellular pores with different ion selectivities
2006
Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis
2012
Claudin‐16 affects transcellular Cl− secretion in MDCK cells
2009
CNS Myelin and Sertoli Cell Tight Junction Strands Are Absent in Osp/Claudin-11 Null Mice
1999
Tissue‐specific expression of the tight junction proteins claudins and occludin in the rat salivary glands
2004
Mechanism of Hypokalemia in Magnesium Deficiency
2007
Thr203 of claudin-1, a putative phosphorylation site for MAP kinase, is required to promote the barrier function of tight junctions
2004
Mineralocorticoid receptor antagonists and kidney diseases: pathophysiological basis
2019
Osteoblasts express claudins and tight junction-associated proteins
2008
Deficiency of Claudin-18 Causes Paracellular H+ Leakage, Up-regulation of Interleukin-1β, and Atrophic Gastritis in Mice
2011
Molecular Basis of Epithelial Barrier Regulation
2006
Developmental Profile of Claudin‐3, ‐5, and ‐16 Proteins in the Epithelium of Chick Intestine
2010
Relapse or Worsening of Nephrotic Syndrome in Idiopathic Membranous Nephropathy Can Occur even though the Glomerular Immune Deposits Have Been Eradicated
2011
Claudins regulate the intestinal barrier in response to immune mediators
2000
Expression, solubilization, and biochemical characterization of the tight junction transmembrane protein claudin‐4
2003
Organization and formation of the tight junction system in human epidermis and cultured keratinocytes
2002
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Diagnosis and Management of the Metabolic Syndrome
2005 Standout
Differential Expression and Subcellular Localization of Claudin-7, −8, −12, −13, and −15 Along the Mouse Intestine
2006
Paracellin-1 and the modulation of ion selectivity of tight junctions
2005
Direct Binding of Three Tight Junction-Associated Maguks, Zo-1, Zo-2, and Zo-3, with the Cooh Termini of Claudins
1999
Population-Based Prevention of Obesity
2008
Magnesium in Man: Implications for Health and Disease
2014 Standout
Claudin Family Proteins in Caenorhabditis elegans
2011
Abnormal Development of Nephrons in <i>Claudin-16</i>- Defective Japanese Black Cattle
2005
Claudin-16 and claudin-19 interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium
2009
Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse
2001 StandoutNobel
Actin Depolymerization Disrupts Tight Junctions via Caveolae-mediated Endocytosis
2005
Tight Junction Transmembrane Protein Claudin Subtype Expression and Distribution in Human Corneal and Conjunctival Epithelium
2009
Paracellular Cl - permeability is regulated by WNK4 kinase: Insight into normal physiology and hypertension
2004
MEMBRANE-ASSOCIATED GUANYLATE KINASES REGULATE ADHESION AND PLASTICITY AT CELL JUNCTIONS
2005
Deletion of CASK in mice is lethal and impairs synaptic function
2007 StandoutNobel
PDZ Protein Interactions Regulating Glutamate Receptor Function and Plasticity
2001
Claudin-2 is selectively expressed in proximal nephron in mouse kidney
2001
Structural and signalling molecules come together at tight junctions
1999
CLAUDINS AND EPITHELIAL PARACELLULAR TRANSPORT
2005
Developmental changes in rabbit proximal straight tubule paracellular permeability
2002
Activation of the Ca2+-sensing receptor increases renal claudin-14 expression and urinary Ca2+ excretion
2013
Conversion of Zonulae Occludentes from Tight to Leaky Strand Type by Introducing Claudin-2 into Madin-Darby Canine Kidney I Cells
2001
Acute kidney injury: a springboard for progression in chronic kidney disease
2010
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
2020 Standout
Occludin 1B, a Variant of the Tight Junction Protein Occludin
2000
Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes
2020 Standout
The Molecular Physiology of Tight Junction Pores
2004
Restoration of Tight Junction Structure and Barrier Function by Down-Regulation of the Mitogen-activated Protein Kinase Pathway in Ras-transformed Madin-Darby Canine Kidney Cells
2000
Phosphorylation of paracellin-1 at Ser217 by protein kinase A is essential for localization in tight junctions
2006
Renal salt wasting and chronic dehydration in claudin-7-deficient mice
2009
Tight junctions in Schwann cells of peripheral myelinated axons
2005
Cloning of the Human Claudin-2 5′-Flanking Region Revealed a TATA-less Promoter with Conserved Binding Sites in Mouse and Human for Caudal-related Homeodomain Proteins and Hepatocyte Nuclear Factor-1α
2002
Targeted deletion of murineCldn16identifies extra- and intrarenal compensatory mechanisms of Ca2+and Mg2+wasting
2010
Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells
2000
Pores in the Wall
2000
Clinical microbiology of coryneform bacteria
1997 Standout
Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins
2004
Claudins create charge-selective channels in the paracellular pathway between epithelial cells
2002
Effects of an Angiotensin-Converting–Enzyme Inhibitor, Ramipril, on Cardiovascular Events in High-Risk Patients
2000 Standout
Harmonizing the Metabolic Syndrome
2009 Standout
Claudins and the Modulation of Tight Junction Permeability
2013 Standout
Segment-specific expression of tight junction proteins, claudin-2 and -10, in the rat epididymal epithelium
2005
Expression and phylogeny of claudins in vertebrate primordia
2001
Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers
2001
Claudin-based tight junctions are crucial for the mammalian epidermal barrier
2002 Standout
Overexpression of claudin-7 decreases the paracellular Cl– conductance and increases the paracellular Na+ conductance in LLC-PK1 cells
2005
2020 International Society of Hypertension Global Hypertension Practice Guidelines
2020 Standout
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure
2006
Claudin-1 gene mutations in neonatal sclerosing cholangitis associated with ichthyosis: A tight junction disease
2004
Claudin-2 is selectively expressed in proximal nephron in mouse kidney
2001
Cyclosporine nephrotoxicity
2003
Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells
2002
claudin-18, a Novel Downstream Target Gene for the T/EBP/NKX2.1 Homeodomain Transcription Factor, Encodes Lung- and Stomach-Specific Isoforms through Alternative Splicing
2001
Claudin-1, −2, −3, −4, −5, and −7 in Usual Interstitial Pneumonia and Sarcoidosis
2008
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Crystal structures of claudins: insights into their intermolecular interactions
2017
Works of Manuel Praga being referenced
Obesity, proteinuria and progression of renal failure
2006
Addition of Spironolactone to Dual Blockade of Renin Angiotensin System Dramatically Reduces Severe Proteinuria in Renal Transplant Patients: An Uncontrolled Pilot Study at 6 Months
2010
Influence of obesity on the appearance of proteinuria and renal insufficiency after unilateral nephrectomy
2000
MEMBRANOUS GLOMERULONEPHRITIS ASSOCIATED WITH HEPATITIS C VIRUS INFECTION IN RENAL TRANSPLANT PATIENTS1,2
1997
Long-Term Beneficial Effects of Angiotensin-Converting Enzyme Inhibition in Patients With Nephrotic Proteinuria
1992
Acute interstitial nephritis
2010
Early steroid treatment improves the recovery of renal function in patients with drug-induced acute interstitial nephritis
2008
Treatment of IgA Nephropathy with ACE Inhibitors
2003
Impact of Left Ventricular Dysfunction on Renal Transplant Survival: Study of Paired Kidneys From the Same Donor
2015
Chronic Kidney Disease as a Situation of High Added Risk in Hypertensive Patients
2006
Mutations in theCOL4A4 and COL4A3 Genes Cause Familial Benign Hematuria
2002
Obesity favors surgical and infectious complications after renal transplantation
2003
Beneficial effects of weight loss in overweight patients with chronic proteinuric nephropathies
2003
Factors influencing the progression of renal damage in patients with unilateral renal agenesis and remnant kidney
2005
Elevation of von Willebrand factor levels in patients with IgA nephropathy: Effect of ACE inhibition
1997
Effects of Body-Weight Loss and Captopril Treatment on Proteinuria Associated with Obesity
1995
Renoprotective effects of mineralocorticoid receptor blockers in patients with proteinuric kidney diseases
2012
ENCRUSTED PYELITIS AND CYSTITIS BY Corynebacterium urealyticum (CDC GROUP D2)
1993
Cyclosporin in idiopathic glomerular disease associated with the nephrotic syndrome : Workshop recommendations
2007
Association of thin basement membrane nephropathy with hypercalciuria, hyperuricosuria and nephrolithiasis
1998
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis
1995
L-arginine reverses the antinatriuretic effect of cyclosporin in renal transplant patients
1997
Long-term renal survival in malignant hypertension
2010
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis
1996
Long-term influences of antihypertensive therapy on microalbuminuria in essential hypertension.
1994
Atypical hemolytic uremic syndrome (aHUS): essential aspects of an accurate diagnosis.
2016
Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg 2+ Resorption
1999 Science
Synergy of low nephron number and obesity: a new focus on hyperfiltration nephropathy
2005