Citation Impact
Citing Papers
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
2006
An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis
2000
Liver fibrosis
2005 Standout
Visible light photoredox catalysis: applications in organic synthesis
2010 Standout
Hyponatremia Treatment Guidelines 2007: Expert Panel Recommendations
2007 Standout
MC4R Agonists: Structural Overview on Antiobesity Therapeutics
2018 StandoutNobel
High‐Throughput Screening for Terpene‐Synthase‐Cyclization Activity and Directed Evolution of a Terpene Synthase
2013 StandoutNobel
Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging
2013 Standout
The antibody-drug conjugate: an enabling modality for natural product-based cancer therapeutics
2013
Marine natural products
1990 Standout
PDGF-Mediated Chemoattraction of Hepatic Stellate Cells by Bile Duct Segments in Cholestatic Liver Injury
2000
Network pharmacology: the next paradigm in drug discovery
2008 Standout
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
The role of endothelin-1 and the endothelin B receptor in the pathogenesis of hepatopulmonary syndrome in the rat
2004
Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension
2002
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Therapy of hyponatremia in cirrhosis with a vasopressin receptor antagonist: A randomized double-blind multicenter trial
2003
PROTAC targeted protein degraders: the past is prologue
2022 Standout
How hydrogen bonds impact P-glycoprotein transport and permeability
2012
Hyponatremia and Mortality among Patients on the Liver-Transplant Waiting List
2008 Standout
Natural sesquiterpenoids
2010
Strategies and challenges for the next generation of antibody–drug conjugates
2017 Standout
CELLUAR PATHOPHYSIOLOGY OF PORTAL HYPERTENSION AND PROSPECTS FOR MANAGEMENT WITH GENE THERAPY
2001
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Kidney function in mice lacking aldosterone
2005 StandoutNobel
Dysregulation of renal aquaporins and Na-Cl cotransporter in CCl4-induced cirrhosis
2000
Peribiliary myofibroblasts in biliary type liver fibrosis
2002
Trends in the Development of New Antidepressants. Is there a Light at the End of the Tunnel?
2004
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis
2002
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
2014
Can a Ketone Be More Reactive than an Aldehyde? Catalytic Asymmetric Synthesis of Substituted Tetrahydrofurans
2018 StandoutNobel
Iron Catalysis in Organic Synthesis
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Synthesis and chiral recognition of helical poly(phenylacetylene)s bearing l ‐phenylglycinol and its phenylcarbamates as pendants
2014
Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy
2012 Standout
Chlorin Photosensitizers Sterically Designed To Prevent Self-Aggregation
2011
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Organic Photoredox Catalysis
2016 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure
2016
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Macrocyclic Peptides as Drug Candidates: Recent Progress and Remaining Challenges
2019
Mild metal-catalyzed C–H activation: examples and concepts
2016 Standout
The Basic and Clinical Pharmacology of Nonpeptide Vasopressin Receptor Antagonists
2001
Accessing Drug Metabolites via Transition‐Metal Catalyzed C−H Oxidation: The Liver as Synthetic Inspiration
2016
Sponge-Associated Microorganisms: Evolution, Ecology, and Biotechnological Potential
2007 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
Advances in singlet oxygen chemistry
2005
The medicinal chemist's toolbox for late stage functionalization of drug-like molecules
2015
Helicenes: Synthesis and Applications
2011 Standout
Finding the sweet spot: the role of nature and nurture in medicinal chemistry
2012
Azine Activation via Silylium Catalysis
2021 StandoutNobel
Macrocycles: lessons from the distant past, recent developments, and future directions
2014
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
Abnormal regulation of ENaC: syndromes of salt retention and salt wasting by the collecting duct
2002
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Endothelial Dysfunction in Salt-Sensitive Essential Hypertension
2001
Using Singlet Oxygen to Synthesize Natural Products and Drugs
2016
ETCM: an encyclopaedia of traditional Chinese medicine
2018 Standout
Photochemical Reactions as Key Steps in Organic Synthesis
2008
Dual Catalysis Strategies in Photochemical Synthesis
2016 Standout
Superoxide Ion: Generation and Chemical Implications
2016 Standout
Synthesis of six-membered oxygenated heterocycles through carbon–oxygen bond-forming reactions
2008
Iron(III) Catalyzed Direct Synthesis of cis-2,7-Disubstituted Oxepanes. The Shortest Total Synthesis of (+)-Isolaurepan
2012
The exciton model in molecular spectroscopy
1965 Standout
Photoredox Catalysis in Organic Chemistry
2016 Standout
Reversible Photochemical Control of Singlet Oxygen Generation Using Diarylethene Photochromic Switches
2014 StandoutNobel
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space
2016
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
2018 Standout
Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety
2011
Aquaporins in the Kidney: From Molecules to Medicine
2002 StandoutNobel
HEPATIC FIBROSIS: Molecular Mechanisms and Drug Targets
2004
Peribiliary myofibroblasts in biliary type liver fibrosis
2002
Biosynthetic medicinal chemistry of natural product drugs
2012
Postsynthetic Incorporation of a Singlet Oxygen Photosensitizer in a Metal–Organic Framework for Fast and Selective Oxidative Detoxification of Sulfur Mustard
2016 StandoutNobel
Works of Manuel Pérez being referenced
Design and synthesis of new potent, silent 5-HT1A antagonists by covalent coupling of aminopropanol derivatives with selective serotonin reuptake inhibitors
1998
Comparison of Two Aquaretic Drugs (Niravoline and OPC-31260) in Cirrhotic Rats with Ascites and Water Retention
1999
Chronic blockade of endothelin receptors in cirrhotic rats: Hepatic and hemodynamic effects
1999
Lead diversification. Application to existing drug molecules: Mifepristone 1 and antalarmin 8
2011
The first enantioselective synthesis of palinurin
2009
1H chemical shifts in NMR: Part 23, the effect of dimethyl sulphoxide versus chloroform solvent on 1H chemical shifts
2006
Synthesis of a chiral building block for highly functionalized polycyclic ethers
2014
Lead Diversification 2: Application to P38, gMTP and lead compounds
2011
The furan approach to oxacycles. Part 3: Stereoselective synthesis of 2,3-disubstituted tetrahydropyrans
2005
A new, enantioselective synthesis of (+)-isolaurepan
2009
Intramolecular hydrogen bonding to improve membrane permeability and absorption in beyond rule of five chemical space
2011
Natural and Unnatural A‐seco Terpenes from Pulegone: Synthesis of Galbanic Acid and Marneral Revisited
2009
The furan approach to oxacycles: synthesis of medium-size 2,3-disubstituted oxacycles
2004