Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Genome sequence of an industrial microorganism Streptomyces avermitilis : Deducing the ability of producing secondary metabolites
2001 StandoutNobel
Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains
2016
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
2005 StandoutNobel
Total synthesis of (+)-papulacandin D
2010
Engineering natural products using combinatorial biosynthesis and biocatalysis
2008
Natural products: A continuing source of novel drug leads
2013 Standout
The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
2002 StandoutNobel
Glucan synthase inhibitors as antifungal agents
2001
Indolocarbazole natural products: occurrence, biosynthesis, and biological activity
2006
Asymmetric spiroacetalization catalysed by confined Brønsted acids
2012 StandoutNatureNobel
Disulfonimide‐Catalyzed Asymmetric Vinylogous and Bisvinylogous Mukaiyama Aldol Reactions
2010 StandoutNobel
The Science of Antibiotic Discovery
2020 Standout
The involvement of RNA in ribosome function
2002 StandoutNatureNobel
Identification of a Novel Acidic Mammalian Chitinase Distinct from Chitotriosidase
2001
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
2003 StandoutNobel
Daptomycin: From the Mountain to the Clinic, with Essential Help from Francis Tally, MD
2010
The Catalytic Asymmetric Acetalization
2013 StandoutNobel
Strained cyclophane natural products: Macrocyclization at its limits
2012
Pharmaceutically active secondary metabolites of microorganisms
1999
Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes
2001
The fungal cell wall as a drug target
1995
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Pneumocandins from Zalerion arboricola. IV. Biological evaluation of natural and semisynthetic pneumocandins for activity against Pneumocystis carinii and Candida species.
1992
Comparison of Caspofungin and Amphotericin B for Invasive Candidiasis
2002 Standout
Patch Clamp Studies on V-type ATPase of Vacuolar Membrane of Haploid Saccharomyces cerevisiae
1999 StandoutNobel
Staurosporine aglycone (K252-c) and arcyriaflavin A from the marine ascidian,Eudistoma sp
1994
One-pot access to l-5,6-dihalotryptophans and l-alknyltryptophans using tryptophan synthase
2016
Iron Catalysis in Organic Synthesis
2015 Standout
Naturally Occurring Oxazole-Containing Peptides
2020
Chemical Tailoring of Teicoplanin with Site-Selective Reactions
2013
Syntheses of Chiral Dispiroacetals from Carbohydrates
1998
Semisynthesis of an Antifungal Lipopeptide Echinocandin
1999
Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center
2006 StandoutNobel
23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
2005 StandoutNobel
Chemistry of Polyvalent Iodine
2008 Standout
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Supramolecular Polymerization
2009 Standout
Synthesis of (R)-(4-Methoxy-3,5-dihydroxyphenyl)glycine Derivatives: The Central Amino Acid of Vancomycin and Related Agents
1996
Antibiotic resistance is ancient
2011 StandoutNature
Synthesis of 2,3′-biindolyls and indolo[3,2-a]carbazoles
2004
Chemical parameters influencing fine-tuning in the binding of macrolide antibiotics to the ribosomal tunnel
2007 StandoutNobel
From Styrenes to Enantiopure α-Arylglycines in Two Steps
1998 StandoutNobel
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Synthesis and Antibacterial Activity of Ketolides (6-O-Methyl-3-oxoerythromycin Derivatives): A New Class of Antibacterials Highly Potent Against Macrolide-Resistant and -Susceptible Respiratory Pathogens
1998
On the [42]Cycloaddition Approach to Indolo[2,3-a]carbazoles
1995
Nonanomeric Spiroketals in Natural Products: Structures, Sources, and Synthetic Strategies
2005
Staurosporine and ent-Staurosporine: The First Total Syntheses, Prospects for a Regioselective Approach, and Activity Profiles1
1996
Practical Methodologies for the Synthesis of Indoles
2006 Standout
In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin
1992
Helical Growth of Semiconducting Columnar Dye Assemblies Based on Chiral Perylene Bisimides
2007
Oral Administration of Chitin Down-Regulates Serum IgE Levels and Lung Eosinophilia in the Allergic Mouse
2000
Control of Dissymmetry in the Synthesis of (+)-Tjipanazole F2
1996
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Cooperative Reactivity in an Extended-Viologen-Based Cyclophane
2016 StandoutNobel
Effective Strategy for the Preparation of Indolocarbazole Aglycons and Glycosides: Total Synthesis of Tjipanazoles B, D, E, and I
2003
Sampling the Antibiotic Resistome
2006 StandoutScience
Microbial metabolites: 45 years of wandering, wondering and discovering
2011 StandoutNobel
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
2013 StandoutNobel
PROGRESS IN THE FISCHER INDOLE REACTION. A REVIEW
1993
Transition Metal-Mediated Cycloaddition Reactions
1996 Standout
Dehydrooligopeptides. XIV. Syntheses of 2-[(Z)-1-Amino-1-alken-1-yl]oxazole-4-carboxylic Acid and the Main Common Skeleton of Thiostrepton Peptide Antibiotics, A10255G and J
1996
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
The First One-Pot Synthesis of l -7-Iodotryptophan from 7-Iodoindole and Serine, and an Improved Synthesis of Other l -7-Halotryptophans
2014
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
2017 StandoutNobel
Ribosomal Synthesis of Dehydroalanine-Containing Peptides
2006 StandoutNobel
Maculalactone L and three halogenated carbazole alkaloids from Kyrtuthrix maculans
1999
Recent progress in the chemistry and applications of indolocarbazoles
2008
Diverse and abundant antibiotic resistance genes in Chinese swine farms
2013 Standout
Catalytic Carbene Insertion into C−H Bonds
2009 Standout
Cyclizations of unsymmetrical bis-1,2-(3-indolyl)ethanes: Synthesis of (−)-tjipanazole F1
1997
Structural basis for cross-resistance to ribosomal PTC antibiotics
2008 StandoutNobel
Synthesis of β-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase
2016 StandoutNobel
Synthetic Approaches to Indolo[2,3-a]carbazole alkaloids. Syntheses of arcyriaflavin A and AT2433-B aglycone
1992
Regiocontrolled Synthesis of the Antitumor Antibiotic AT2433-A1
2000
Recent Advances in Efficient and Selective Synthesis of Di-, Tri-, and Tetrasubstituted Alkenes via Pd-Catalyzed Alkenylation−Carbonyl Olefination Synergy
2008 StandoutNobel
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Enantioselective Formation of Bicyclic Lactones by Rhodium‐Catalyzed Intramolecular CH‐insertion reactions
1994
A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation
2016 StandoutNobel
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Efficient production of aculeacin A acylase in recombinant Streptomyces strains
1993 StandoutNobel
In vitro activities of semisynthetic pneumocandin L-733,560 against fluconazole-resistant and -susceptible Candida albicans isolates
1996
Catalytic Asymmetric Transacetalization
2010 StandoutNobel
The rhodium carbenoid route to oxazoles. Synthesis of 4-functionalised oxazoles; Three step preparation of a bis-oxazole
1994
High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: Mimicry of carbohydrate substrate
2002 StandoutNobel
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Challenges of Antibacterial Discovery
2011
Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-D-glucosamine, in mice
1997
Electrophilic substitution and cyclization of 2,2′‐bis(N‐methylindolyl): A simple access to potential protein kinase C inhibitor
1994
Total Synthesis and Structural Elucidation of the Antifungal Agent Papulacandin D
1996
Thiopeptide Antibiotics
2005
Works of Manuel Debono being referenced
Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics
1988
Anti‐Candida Activity and Toxicology of LY121019, a Novel Semisynthetic Polypeptide Antifungal Antibiotica
1988
Deacylation of A21978C, an acidic lipopeptide antibiotic complex, by Actinoplanes utahensis.
1988
ANTIBIOTICS THAT INHIBIT FUNGAL CELL WALL DEVELOPMENT
1994
Deacylation of echinocandin B by Actinoplanes utahensis.
1989
Synthesis and structure-activity relationships of new 9-N-alkyl derivatives of 9(S)-erythromycylamine
1990
Synthesis and Evaluation of LY121019, a Member of a Series of Semisynthetic Analogues of the Antifungal Lipopeptide Echinocandin Ba
1988
Synthesis and antimicrobial evaluation of 20-deoxo-20(3,5-dimethylpiperidin-1-yl)desmycosin (tilmicosin, EL-870) and related cyclic amino derivatives.
1989
Semisynthetic Chemical Modification of the Antifungal Lipopeptide Echinocandin B (ECB): Structure-Activity Studies of the Lipophilic and Geometric Parameters of Polyarylated Acyl Analogs of ECB
1995
Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: The synthesis and evaluation of daptomycin (LY146032).
1988
Synthesis of new analogs of echinocandin B by enzymatic deacylation and chemical reacylation of the echinocandin B peptide: Synthesis of the antifungal agent cilofungin (LY121019).
1989
Tjipanazoles, new antifungal agents from the blue-green alga Tolypothrix tjipanasensis
1991
Structure of the major glycopeptide of the teicoplanin complex
1984
The structures of A10255 B, -G and -J: new thiopeptide antibiotics produced by Streptomyces gardneri
1992
Studies of Terpene Chemistry. I. The Acid-Catalyzed Dimerization of Citronellal1
1964
Structure of the pseudoaglycon of actaplanin
1984
The preparatiom and chemistsy of the 10α-estra-4- en-3-ones
1966
The echinocandins: antifungals targeted to the fungal cell wall
1994
The structure of the calcium complex of A23187, a divalent cation ionophore antibiotic.
1976
A21978C, a complex of new acidic peptide antibiotics. Isolation, chemistry, and mass spectral structure elucidation.
1987
The structure of narasin and a related ionophore
1976
A 35512, a complex of new antibacterial antibiotics produced by Streptomyces candidus. II. Chemical studies on A35512B.
1980