Citation Impact

Citing Papers

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
RAS Mutations Contribute to Evolution of Chronic Myelomonocytic Leukemia to the Proliferative Variant
2010
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
2011 StandoutScience
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
Reduced TET2 function leads to T-cell lymphoma with follicular helper T-cell-like features in mice
2014
The molecular hallmarks of epigenetic control
2016 Standout
Functions of DNA methylation: islands, start sites, gene bodies and beyond
2012 Standout
Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues
2009
CpG islands and the regulation of transcription
2011 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation
2011
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
Active DNA demethylation: many roads lead to Rome
2010
From human genome to cancer genome: The first decade
2013
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
The Cancer Genome Atlas Pan-Cancer analysis project
2013 Standout
Cancer stem cells revisited
2017 Standout
DNA methylation: roles in mammalian development
2013 Standout
Hypoxia signaling pathways in cancer metabolism: the importance of co-selecting interconnected physiological pathways
2014 StandoutNobel
Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism
2018 Standout
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Advances in DNA methylation: 5-hydroxymethylcytosine revisited
2011
Dysplasia Has A Differential Diagnosis: Distinguishing Genuine Myelodysplastic Syndromes (MDS) From Mimics, Imitators, Copycats and Impostors
2012
An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms
2015
DNA Methylation and Its Basic Function
2012 Standout
U1 snRNP regulates cancer cell migration and invasion in vitro
2020 Standout
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing
2010
U2AF1 mutations alter splice site recognition in hematological malignancies
2014
Clinical Effect of Point Mutations in Myelodysplastic Syndromes
2011 Standout
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
2013 Standout
Driver mutations of cancer epigenomes
2014
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
2010 Nature
The cancer stem cell: premises, promises and challenges
2011 Standout
Impact of molecular mutations on treatment response to DNMT inhibitors in myelodysplasia and related neoplasms
2013
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias
2010
5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy
2015
Effects ofTET2mutations on DNA methylation in chronic myelomonocytic leukemia
2012
Therapy with azanucleosides for myelodysplastic syndromes
2010
Regulation of c-Myc Ubiquitination Controls Chronic Myelogenous Leukemia Initiation and Progression
2013
A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
Maftools: efficient and comprehensive analysis of somatic variants in cancer
2018 Standout
Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes
2015
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
DNA methylation: TET proteins—guardians of CpG islands?
2011
Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Issue
2019 Standout
Clinical activity and safety of the dual pathway inhibitor rigosertib for higher risk myelodysplastic syndromes following DNA methyltransferase inhibitor therapy
2014
Recent developments in myelodysplastic syndromes
2014
Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms
2012
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
2011
Acute Myeloid Leukemia
2015 Standout
Fundamentals of cancer metabolism
2016 Standout
Molecular and prognostic correlates of cytogenetic abnormalities in chronic myelomonocytic leukemia: a Mayo Clinic‐French Consortium Study
2014
New Ways to Use DNA Methyltransferase Inhibitors for the Treatment of Myelodysplastic Syndrome
2011
Hypomethylating agent combination strategies in myelodysplastic syndromes: hopes and shortcomings
2016
How I treat acquired aplastic anemia
2012
Epigenetic control of thymic Treg‐cell development
2014 StandoutNobel
The emerging role of immune checkpoint based approaches in AML and MDS
2017 StandoutNobel
Recent advances in understanding the molecular pathogenesis of myelodysplastic syndromes
2013
Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression
2019 StandoutNobel
TET proteins and 5‐methylcytosine oxidation in hematological cancers
2014
RUNX1Mutations in Acute Myeloid Leukemia: Results From a Comprehensive Genetic and Clinical Analysis From the AML Study Group
2011
Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A
2011
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
2011
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
2015 Standout
TET2 Mutations in Acute Myeloid Leukemia (AML): Results From a Comprehensive Genetic and Clinical Analysis of the AML Study Group
2012
Mechanisms and Regulation of Alternative Pre-mRNA Splicing
2015
Treatment options for patients with myelodysplastic syndromes after hypomethylating agent failure
2016
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value
2010

Works of Manuel Afable being referenced

Phase I Combination Trial of Lenalidomide and Azacitidine in Patients With Higher-Risk Myelodysplastic Syndromes
2010
A Phase 2 study of combination therapy with arsenic trioxide and gemtuzumab ozogamicin in patients with myelodysplastic syndromes or secondary acute myeloid leukemia
2010
Efficacy of rabbit anti-thymocyte globulin in severe aplastic anemia
2011
Demonstration of additional benefit in adding lenalidomide to azacitidine in patients with higher‐risk myelodysplastic syndromes
2010
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms
2009
Clonal Evolution in Aplastic Anemia
2011
SNP array–based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes
2011
Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis
2012
Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes
2012
Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia
2012
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2026