Citation Impact
Citing Papers
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
Modified DNA Aptamer That Binds the ( R )-Isomer of a Thalidomide Derivative with High Enantioselectivity
2007
De novo design and directed folding of disulfide-bridged peptide heterodimers
2022 StandoutNobel
Topoisomerase II as a target for anticancer drugs: When enzymes stop being nice
2000
Rhodamines NN: A Novel Class of Caged Fluorescent Dyes
2010 StandoutNobel
Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV
2011
Mesoporous silica nanoparticles in biomedical applications
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Cell‐Penetrating, Dimeric α‐Helical Peptides: Nanomolar Inhibitors of HIV‐1 Transcription
2014
Chiral Recognition in Bis-Urea-Based Aggregates and Organogels through Cooperative Interactions
2001 StandoutNobel
Rethinking amide bond synthesis
2011 StandoutNature
Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases
2010
Brønsted Acid‐Catalyzed, Highly Enantioselective Addition of Enamides to In Situ‐Generated ortho‐Quinone Methides: A Domino Approach to Complex Acetamidotetrahydroxanthenes
2014
DNA gyrase as a drug target
1997
Participation of Reactive Oxygen Species in Phototoxicity Induced by Quinolone Antibacterial Agents
1997
Conformational Control of Energy Transfer: A Mechanism for Biocompatible Nanocrystal‐Based Sensors
2012 StandoutNobel
Mononuclear Fe(ii)-N4Py complexes in oxidative DNA cleavage: structure, activity and mechanism
2010 StandoutNobel
Directed evolution to increase camptothecin sensitivity of human DNA topoisomerase I
2001
DNA topoisomerase II, genotoxicity, and cancer
2007
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Structural and catalytic roles for divalent magnesium in nucleic acid biochemistry
2002
Pegylated liposomal doxorubicin and gemcitabine in patients with advanced hepatocellular carcinoma
2010
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Targeting multidrug resistance in cancer
2006 Standout
Drug Interactions with Bacillus anthracis Topoisomerase IV: Biochemical Basis for Quinolone Action and Resistance
2011
Prospective therapeutic applications of p53 inhibitors
2005
Structural insight into the quinolone–DNA cleavage complex of type IIA topoisomerases
2009
Strategies to Inhibit Myc and Their Clinical Applicability
2017
Adaptive Recognition of Small Molecules by Nucleic Acid Aptamers through a Label‐Free Approach
2007
Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance
2013
The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing
2008
ortho‐Quinone Methides in Natural Product Synthesis
2012
Molecular Analysis of Yeast and Human Type II Topoisomerases
1999 Nobel
Photo-mediated gene activation using caged RNA/DNA in zebrafish embryos
2001 StandoutNobel
The use of divalent metal ions by type II topoisomerases
2010
Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM
2009 StandoutNobel
Aptamer-based label-free method for hemin recognition and DNA assay by capillary electrophoresis with chemiluminescence detection
2007
Recognition of the DNA minor groove by pyrrole-imidazole polyamides
2003
In vitro selection of allosteric ribozymes: theory and experimental validation11Edited by R. Huber
2001
Effects of Uracil Incorporation, DNA Mismatches, and Abasic Sites on Cleavage and Religation Activities of Mammalian Topoisomerase I
1997 StandoutNobel
The Organocatalytic Asymmetric Prins Cyclization
2015 StandoutNobel
Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance
2010
A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics
2007 Standout
Mechanism of Quinolone Action and Resistance
2014 Standout
Metal-Catalyzed Copolymerization of Imines and CO: A Non-Amino Acid Route to Polypeptides
2007
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
2015 StandoutNobel
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
Efficient Generation of ortho-Quinone Methide: Application to the Biomimetic Syntheses of (±)-Schefflone and Tocopherol Trimers
2011
Metal−Peptide Frameworks (MPFs): “Bioinspired” Metal Organic Frameworks
2008
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Functional Nucleic Acid Sensors
2009 Standout
Signaling Recognition Events with Fluorescent Sensors and Switches
1997 Standout
Thermoregulated Optical Properties of Peptidic Pseudorotaxanes
2000 StandoutNobel
TROSY in triple-resonance experiments: New perspectives for sequential NMR assignment of large proteins
1998 StandoutNobel
Structure of β-sheets
1982
Generation and Conjugate Additions of o‐Quinone Methides Under Mild Base Conditions: Rapid Synthesis of N‐Substituted Aryl Glycine Derivatives
2013
Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites.
1995 StandoutNobel
Probing the Differential Interactions of Quinazolinedione PD 0305970 and Quinolones with Gyrase and Topoisomerase IV
2009
Ion-dependent protein–surface interactions from intrinsic solvent response
2021 StandoutNobel
Conceptual Density Functional Theory
2003 Standout
Facile Conversion of Aptamers into Sensors Using a 2‘-Ribose-Linked Fluorophore
2005
Fluorophore Targeting to Cellular Proteins via Enzyme-Mediated Azide Ligation and Strain-Promoted Cycloaddition
2012 StandoutNobel
Mechanism of quinolone inhibition of DNA gyrase
1989
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
Non-Nucleoside Building Blocks for Copper-Assisted and Copper-Free Click Chemistry for the Efficient Synthesis of RNA Conjugates
2010
Design and synthesis of novel peptides bearing a host and a guest side chains
1994
Determination of Alkali and Halide Monovalent Ion Parameters for Use in Explicitly Solvated Biomolecular Simulations
2008 Standout
BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties
2007 Standout
RNA Catalysis in Model Protocell Vesicles
2005 StandoutNobel
Spin—spin coupling and the conformational states of peptide systems
1976
Photochemical Reactions as Key Steps in Organic Synthesis
2008
The use of peptidic frameworks for the construction of molecular receptors and devices
1995
Interaction between DNA Gyrase and Quinolones: Effects of Alanine Mutations at GyrA Subunit Residues Ser 83 and Asp 87
2001
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
Quinolone-Mediated Bacterial Death
2007
Saintopin, a dual inhibitor of DNA topoisomerases I and II, as a probe for drug-enzyme interactions.
1994
Bacterial Topoisomerase Inhibitors: Quinolone and Pyridone Antibacterial Agents
2005
Applications of ortho-Quinone Methide Intermediates in Catalysis and Asymmetric Synthesis
2011
Chiral Phosphoric Acid Catalyzed Conversion of Epoxides into Thiiranes: Mechanism, Stereochemical Model, and New Catalyst Design
2021 StandoutNobel
Quantum Mechanical and Experimental Validation that Cyclobis(paraquat‐p‐phenylene) Forms a 1:1 Inclusion Complex with Tetrathiafulvalene
2016 StandoutNobel
Influence of Constitution and Charge on Radical Pairing Interactions in Tris-radical Tricationic Complexes
2016 StandoutNobel
Catalytic Asymmetric Intramolecular [4+2] Cycloaddition of In Situ Generated ortho‐Quinone Methides
2017 StandoutNobel
Emerging Targets in Photopharmacology
2016 StandoutNobel
Metal–Organic Frameworks for Separations
2011 Standout
Metal–Organic Frameworks in Biomedicine
2011 Standout
Experimental study on aggregation of model dipeptide molecules. V. Stereoselective association of leucine dipeptides
1978
A DNA Aptamer as a New Target-Specific Chiral Selector for HPLC
2003
Engineering Metal Organic Frameworks for Heterogeneous Catalysis
2010 Standout
A Chemical Approach to Protein Design—Template‐Assembled Synthetic Proteins (TASP)
1989
Solution structure of murine epidermal growth factor: determination of the polypeptide backbone chain-fold by nuclear magnetic resonance and distance geometry.
1987 StandoutNobel
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
NMR scalar couplings across Watson–Crick base pair hydrogen bonds in DNA observed by transverse relaxation-optimized spectroscopy
1998 StandoutNobel
Synthesis of Side-Chain Modified Polypeptides
2015
Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
2011 StandoutScience
Attenuated T 2 relaxation by mutual cancellation of dipole–dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution
1997 StandoutNobel
Molecular Self-Assembly and Nanochemistry: a Chemical Strategy for the Synthesis of Nanostructures
1991 StandoutScience
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
2018 StandoutNobel
Brominated 7-hydroxycoumarin-4-ylmethyls: Photolabile protecting groups with biologically useful cross-sections for two photon photolysis
1999 StandoutNobel
Works of Manlio Palumbo being referenced
A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.
2001
Mapping Drug Interactions at the Covalent Topoisomerase II-DNA Complex by Bisantrene/Amsacrine Congeners
1998
DNA Phosphodiester Bond Hydrolysis Mediated by Cu(II) and Zn(II) Complexes of 1,3,5,-Triamino-cyclohexane Derivatives
2000
Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage
2008
Perylene side chains modulate G-quadruplex conformation in biologically relevant DNA sequences
2008
Effects of magnesium and related divalent metal ions in topoisomerase structure and function
2009
The Effects of Metal Ions on the Structure and Stability of the DNA Gyrase B Protein
2005
Involvement of p53 in specific anti‐neuroectodermal tumor activity of aloe‐emodin
2003
Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases
2007
SYNTHESIS AND PHOTOBIOLOGICAL PROPERTIES OF 4‐HYDROXYMETHYL‐4′‐METHYLPSORALEN DERIVATIVES
1993
Novel Symmetric and Asymmetric DNA Scission Determinants for Streptococcus pneumoniae Topoisomerase IV and Gyrase Are Clustered at the DNA Breakage Site
2005
A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons
1997
Synthesis and biological evaluation of 2-phenylquinolones targeted at Tat/TAR recognition
2008
Studies of Anti‐HIV Transcription Inhibitor Quinolones: Identification of Potent N1‐Vinyl Derivatives
2010
On the mechanism of action of quinolone drugs
1993
In vitro selection of DNA aptamers that bind l-tyrosinamide
2001
Ciprofloxacin affects conformational equilibria of DNA gyrase A in the presence of magnesium ions
2001
Topoisomerase I, IIα and IIβ mRNA expression in peripheral blood mononuclear cells of patients with solid tumor: preliminary results
2006
Tri-, tetra- and heptacyclic perylene analogues as new potential antineoplastic agents based on DNA telomerase inhibition
2006
Mg2+-mediated binding of 6-Substituted quinolones to DNA: relevance to biological activity
1998
In vitro basis for schedule-dependent interaction between gemcitabine and topoisomerase-targeted drugs in the treatment of colorectal cancer
2006
Do quinolones bind to DNA?
1988
Conformational Drug Determinants of the Sequence Specificity of Drug-stimulated Topoisomerase II DNA Cleavage
1994
DNA-Binding Preferences of Bisantrene Analogues: Relevance to the Sequence Specificity of Drug-Mediated Topoisomerase II Poisoning
1998
In front of and behind the replication fork: bacterial type IIA topoisomerases
2010
Solid‐state infrared absorption spectra and chain arrangement in some synthetic homooligopeptides in the intermolecularly hydrogen‐bonded pleated‐sheet β‐conformation
1977
Quinone Methide Generation via Photoinduced Electron Transfer
2011
Sequence selectivity of topoisomerase II DNA cleavage stimulated by mitoxantrone derivatives: relationships to drug DNA binding and cellular effects.
1993
Quinone Methides Tethered to Naphthalene Diimides as Selective G-Quadruplex Alkylating Agents
2009
Unique sequence specificity of topoisomerase II DNA cleavage stimulation and DNA binding mode of streptonigrin.
1994
Toward Efficient Zn(II)-Based Artificial Nucleases
2004
DNA Gyrase Requires DNA for Effective Two-Site Coordination of Divalent Metal Ions: Further Insight into the Mechanism of Enzyme Action
2008
Advances in DNA Sequence Specific Agents
1998
Irreversible and reversible topoisomerase II DNA cleavage stimulated by clerocidin: sequence specificity and structural drug determinants.
1997
Synthesis and conformational analysis of cyclo-TRI[l-valyl-d-hexahydromandelyl]
1974
Binol Quinone Methides as Bisalkylating and DNA Cross-Linking Agents
2004
Linear oligopeptides, 29. Infrared conformational analysis of homo‐oligopeptides in the solid state and in solution
1976
N-Substituted Poly(α-amino acids). 1. Synthesis and Characterization of Poly(N-methyl-γ-methyl L-glutamate) and Poly(N-methyl-γ-ethyl L-glutamate)
1978
Synthesis and conformational properties of polypeptides containing long aliphatic side chains. Poly(Nε‐stearyl‐L ‐lysine) and poly(Nε‐pelargonyl‐L ‐lysine)
1975
Quinolone binding to DNA is mediated by magnesium ions.
1992
Linear oligopeptides, 55. Infrared conformational analysis of polyethyleneglycol‐bound alanine and valine homo‐L ‐oligopeptides in the solid state and in solution
1979
Drugs Acting on DNA Topoisomerases: Recent Advances and Future Perspectives
1999
A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons
1997
BINOL−Amino Acid Conjugates as Triggerable Carriers of DNA-Targeted Potent Photocytotoxic Agents
2007