Citation Impact
Citing Papers
A2A adenosine receptor protects tumors from antitumor T cells
2006
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
2012
Identification of Ectonucleotidases CD39 and CD73 in Innate Protection during Acute Lung Injury
2007
A2A Adenosine Receptor May Allow Expansion of T Cells Lacking Effector Functions in Extracellular Adenosine-Rich Microenvironments
2009
Differentiation Stage-Specific Requirement in Hypoxia-Inducible Factor-1α–Regulated Glycolytic Pathway during Murine B Cell Development in Bone Marrow
2009 StandoutNobel
A3 Adenosine Receptor Activation Inhibits Cell Proliferation via Phosphatidylinositol 3-Kinase/Akt-dependent Inhibition of the Extracellular Signal-regulated Kinase 1/2 Phosphorylation in A375 Human Melanoma Cells
2005
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Composition of the endothelial glycocalyx and its relation to its thickness and diffusion of small solutes
2010
A2B adenosine receptor dampens hypoxia-induced vascular leak
2007
Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults
2009
Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease
2012
Adenosine Receptors in Health and Disease
2011
Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues
2007
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Oxygen-Independent Stabilization of Hypoxia Inducible Factor (HIF)-1 during RSV Infection
2008
Nucleotide signalling during inflammation
2014 StandoutNature
Sepsis and Major Abdominal Surgery Lead to Flaking of the Endothelial Glycocalix
2009
Enhanced Interferon-γ Gene Expression in T Cells and Reduced Ovalbumin-Dependent Lung Eosinophilia in Hypoxia-Inducible Factor-1-α-Deficient Mice
2009 StandoutNobel
A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
2008
Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
2011
Hypoxia and Inflammation
2011 Standout
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Adenosine receptors as therapeutic targets
2006 Standout
Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection
2014
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia
2012
Hypoxia Inducible Factor (HIF)-1 Coordinates Induction of Toll-Like Receptors TLR2 and TLR6 during Hypoxia
2007
T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response
2009
Regulation of hypoxia adaptation: an overlooked virulence attribute of pathogenic fungi?
2010
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
2008
Severe Sepsis and Septic Shock
2013 Standout
Roles of SIRT1 in the Acute and Restorative Phases following Induction of Inflammation
2010
Therapeutic potential of adenosine A2A receptor antagonists in Parkinson's disease
2004
A High Admission Syndecan-1 Level, A Marker of Endothelial Glycocalyx Degradation, Is Associated With Inflammation, Protein C Depletion, Fibrinolysis, and Increased Mortality in Trauma Patients
2011
Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock*
2005
Revised Starling equation and the glycocalyx model of transvascular fluid exchange: an improved paradigm for prescribing intravenous fluid therapy
2012
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Targeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer
2013
Revealing the human mucinome
2022 StandoutNobel
Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia
2009
INCREASED LEVELS OF GLYCOSAMINOGLYCANS DURING SEPTIC SHOCK
2008
The Hydroxylase Inhibitor Dimethyloxallyl Glycine Attenuates Endotoxic Shock Via Alternative Activation of Macrophages and IL-10 Production by B1 Cells
2011
Hydrocortisone Therapy for Patients with Septic Shock
2008 Standout
T-Cell Activation under Hypoxic Conditions Enhances IFN-γ Secretion
2009 StandoutNobel
Preferential expression of the novel alternative isoform I.3 of hypoxia-inducible factor 1α in activated human T lymphocytes
2008
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Regulation of immune cells by local-tissue oxygen tension: HIF1α and adenosine receptors
2005
Cancer immunotherapy comes of age
2011 StandoutNature
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Adenosine, an endogenous distress signal, modulates tissue damage and repair
2007
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
2010
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Addicted to Death
2004
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
2013 Standout
ATP Release from Vascular Endothelia Occurs Across Cx43 Hemichannels and Is Attenuated during Hypoxia
2008
Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury
2004
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
CD39/Adenosine Pathway Is Involved in AIDS Progression
2011
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
The Hallmarks of Aging
2013 Standout
Interdependence of hypoxic and innate immune responses
2009
Hypoxia inducible factor (HIF) function in innate immunity and infection
2007
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
The Reno-Vascular A2B Adenosine Receptor Protects the Kidney from Ischemia
2008
Intravenous Fluids and Acute Kidney Injury
2017 Standout
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
2009
The Emerging Role of the Mammalian Glycocalyx in Functional Membrane Organization and Immune System Regulation
2020
Targeting adenosine A2A receptors in Parkinson's disease
2006
Purinergic Signaling during Inflammation
2012
Attenuating myocardial ischemia by targeting A2B adenosine receptors
2013
Oxygen homeostasis
2009 StandoutNobel
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?
2016
Immunologic and Hemodynamic Effects of “Low-Dose” Hydrocortisone in Septic Shock
2003
A2A Adenosine Receptor Induction Inhibits IFN-γ Production in Murine CD4+ T Cells
2005
Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury
2013
Adenosine: An Old Drug Newly Discovered
2009
Down-regulation of MicroRNA-31 in CD4+ T Cells Contributes to Immunosuppression in Human Sepsis by Promoting TH2 Skewing
2016
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery
2011
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
Highly Enantioselective Rhodium-Catalyzed Hydrogenation with Monodentate Ligands
2000 StandoutNobel
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression
2007
Total synthesis of (−)-physovenine from (−)-3a-hydroxyfuroindoline
2005 StandoutNobel
HIF-1α Overexpression and Experimental Murine Atherosclerosis
2009
Cardioprotection by Ecto-5′-Nucleotidase (CD73) and A 2B Adenosine Receptors
2007
Requirements for T Lymphocyte Migration in Explanted Lymph Nodes
2007
Cutting Edge: Hypoxia-Inducible Factor 1α and Its Activation-Inducible Short Isoform I.1 Negatively Regulate Functions of CD4+ and CD8+ T Lymphocytes
2006
Adenosine A2a receptor-mediated, normoxic induction of HIF-1 through PKC and PI-3K-dependent pathways in macrophages
2007
Hypoxia-Inducible Factor-1 Is Central to Cardioprotection
2008
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
2007
Immunological mechanisms of the antitumor effects of supplemental oxygenation
2015
Signaling through the A2B Adenosine Receptor Dampens Endotoxin-Induced Acute Lung Injury
2010
HIF-1–dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia
2005
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Hypoxia-Inducible Factor–Dependent Repression of Equilibrative Nucleoside Transporter 2 Attenuates Mucosal Inflammation During Intestinal Hypoxia
2008
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Central role of Sp1-regulated CD39 in hypoxia/ischemia protection
2008
Loss of Endothelial Glycocalyx During Acute Hyperglycemia Coincides With Endothelial Dysfunction and Coagulation Activation In Vivo
2006
HIF‐dependent induction of adenosine A2B receptor in hypoxia
2006
Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia
2004
A2B Adenosine Receptor Blockade Enhances Macrophage-Mediated Bacterial Phagocytosis and Improves Polymicrobial Sepsis Survival in Mice
2011
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26
2006
Identification of Purα as a New Hypoxia Response Factor Responsible for Coordinated Induction of the β2 Integrin Family
2007
Unusual amino acids VI. Substituted arylamino acids by asymmetric hydrogenation ofN-Cbz andN-Boc protected dehydroamino acid derivatives
1996
A2B Adenosine Receptors Protect against Sepsis-Induced Mortality by Dampening Excessive Inflammation
2010
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Asymmetric Total Synthesis of Neoxaline
2013 StandoutNobel
A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment
2016
Covid-19 in Critically Ill Patients in the Seattle Region — Case Series
2020 Standout
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Adenosine and inflammation: CD39 and CD73 are critical mediators in LPS‐induced PMN trafficking into the lungs
2008
Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis
2019
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
CD73 + regulatory T cells contribute to adenosine‐mediated resolution of acute lung injury
2013
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Cutting Edge: A2B Adenosine Receptor Signaling Provides Potent Protection during Intestinal Ischemia/Reperfusion Injury
2009
Works of Manfred Thiel being referenced
Critical Role of Hypoxia and A2A Adenosine Receptors in Liver Tissue-Protecting Physiological Anti-Inflammatory Pathway
2008
Shedding of the Endothelial Glycocalyx in Patients Undergoing Major Vascular Surgery With Global and Regional Ischemia
2007
The critical role of adenosine A2A receptors in downregulation of inflammation and immunity in the pathogenesis of infectious diseases
2003
Stress doses of hydrocortisone in septic shock: beneficial effects on opsonization-dependent neutrophil functions
2007
Oxygenation Inhibits the Physiological Tissue-Protecting Mechanism and Thereby Exacerbates Acute Inflammatory Lung Injury
2005
Targeted Deletion of HIF-1α Gene in T Cells Prevents their Inhibition in Hypoxic Inflamed Tissues and Improves Septic Mice Survival
2007
First Clinical Implications of Perioperative Red Cell Volume Measurement with a Nonradioactive Marker (Sodium Fluorescein)
1998
A novel route to 3-alkylated estra-1,3,5(10)-trienes
1988
Physiological Control of Immune Response and Inflammatory Tissue Damage by Hypoxia -Inducible Factors and Adenosine A2AReceptors
2004 Nobel
Effects of General Anesthesia on Anandamide Blood Levels in Humans
2006
Regioselective functionalization of 3-oxygenated estra-1,3,5(10)-trienes AT C-1 VIA (η6-arene)Cr(CO)3 complexes
1988
Protective effects of pentoxifylline in pulmonary inflammation are adenosine receptor A 2A dependent
2013
Immunomodulation in Septic Shock
2001
First Clinical Implications of Perioperative Red Cell Volume Measurement with a Nonradioactive Marker (Sodium Fluorescein)
1998