Citation Impact
Citing Papers
Oncogenic Activity of Epidermal Growth Factor Receptor Kinase Mutant Alleles Is Enhanced by the T790M Drug Resistance Mutation
2007
Divergent sodium channel defects in familial hemiplegic migraine
2008
Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility
2021 StandoutNobel
Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Lung Cancer: Distinct Natural History of Patients with Tumors Harboring the T790M Mutation
2010
Genetic and Functional Studies Implicate HIF1 α as a 14q Kidney Cancer Suppressor Gene
2011 StandoutNobel
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non–Small Cell Lung Cancer Cell Line
2007
The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage
2013
Cellular and Gene Expression Responses Involved in the Rapid Growth Inhibition of Human Cancer Cells by RNA Interference-mediated Depletion of Telomerase RNA
2005 StandoutNobel
Involvement of Members of the Cadherin Superfamily in Cancer
2009
Partial chromosome 21 amplification in a child with acute lymphoblastic leukemia
1995
Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers
2002
IDH1andIDH2Mutations in Gliomas
2009 Standout
Involvement of the Pro-oncoprotein TLS (Translocated in Liposarcoma) in Nuclear Factor-κB p65-mediated Transcription as a Coactivator
2001
A view on drug resistance in cancer
2019 StandoutNature
Deconstruction of the SS18-SSX Fusion Oncoprotein Complex: Insights into Disease Etiology and Therapeutics
2012 Nobel
The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
2004 Nature
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
2009 StandoutNature
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
2009 Standout
NaV1.1 channels and epilepsy
2010
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
The biology and management of non-small cell lung cancer
2018 StandoutNature
Epidermal growth factor receptor mutations in lung cancer
2007 Standout
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
2010
Lung Cancer
2008 Standout
Double mutation and gene copy number of EGFR in gefitinib refractory non-small-cell lung cancer
2006
Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
2016 Standout
SWI/SNF nucleosome remodellers and cancer
2011 Standout
Role of the proto-oncogene Pokemon in cellular transformation and ARF repression
2005 Nature
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Sin3: Master scaffold and transcriptional corepressor
2009
Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis
2016
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 StandoutNobel
The Hallmarks of Cancer
2000 Standout
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
The molecular biology of head and neck cancer
2010 Standout
Genetic Patterns in Head and Neck Cancers That Contain or Lack Transcriptionally Active Human Papillomavirus
2004
Protein tyrosine phosphatases: from genes, to function, to disease
2006
Epigenetics in Cancer
2008 Standout
The complexity of NF-κB signaling in inflammation and cancer
2013 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI
2019 StandoutNobel
Global loss of imprinting leads to widespread tumorigenesis in adult mice
2005
The SWI/SNF complex and cancer
2009
Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system
2014
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Factors underlying sensitivity of cancers to small-molecule kinase inhibitors
2009
The ING gene family in the regulation of cell growth and tumorigenesis
2008
Detection of Mutations in EGFR in Circulating Lung-Cancer Cells
2008
A Translational View of the Molecular Pathogenesis of Lung Cancer
2007
Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer
2010 Standout
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
EMT: 2016
2016 Standout
A survey of telomerase activity in human cancer
1997 Standout
Intranuclear Aggregation of Mutant FUS/TLS as a Molecular Pathomechanism of Amyotrophic Lateral Sclerosis
2013
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus
2005
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
2005 StandoutNature
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
PU.1 Activates Transcription of SHP-1 Gene in Hematopoietic Cells
2007
CDK Inhibitors: Cell Cycle Regulators and Beyond
2008
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition
2004
Creation of human tumour cells with defined genetic elements
1999 StandoutNature
Sodium channelSCN1Aand epilepsy: Mutations and mechanisms
2010
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
2007 StandoutNature
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
2005 StandoutNature
The MYST family of histone acetyltransferases and their intimate links to cancer
2007
Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
2010
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
The positive feedback between Snail and DAB2IP regulates EMT, invasion and metastasis in colorectal cancer
2015
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1999 StandoutNobel
RGG/RG Motif Regions in RNA Binding and Phase Separation
2018
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA
2012
Self-assembled FUS binds active chromatin and regulates gene transcription
2014
Specific EGFR Mutations Predict Treatment Outcome of Stage IIIB/IV Patients With Chemotherapy-Naive Non–Small-Cell Lung Cancer Receiving First-Line Gefitinib Monotherapy
2008
Promoter Hypermethylation of Multiple Genes in Sputum Precedes Lung Cancer Incidence in a High-Risk Cohort
2006
Telomerase Catalytic Subunit Homologs from Fission Yeast and Human
1997 StandoutScienceNobel
First-Line Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer Harboring SomaticEGFRMutations
2008
Cancer Genome Landscapes
2013 StandoutScience
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Pharmacology of the Na v 1.1 domain IV voltage sensor reveals coupling between inactivation gating processes
2017 StandoutNobel
Genetic Pathways to Glioblastoma
2004
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout
Genetic Signatures of HPV-related and Unrelated Oropharyngeal Carcinoma and Their Prognostic Implications
2009
Works of Mamoru Ouchida being referenced
TLS/FUS fusion domain of TLS/FUS-erg chimeric protein resulting from the t(16;21) chromosomal translocation in human myeloid leukemia functions as a transcriptional activation domain.
1994
Osteoclast-Derived Zinc Finger (OCZF) Protein With POZ Domain, a Possible Transcriptional Repressor, Is Involved in Osteoclastogenesis
1999
Positive correlation between allelic loss at chromosome 14q24-31 and poor prognosis of patients with renal cell carcinoma
2004
Aberrant promoter methylation of human DAB2 interactive protein (hDAB2IP) gene in lung cancers
2004
Frequent deletion and down-regulation of ING4, a candidate tumor suppressor gene at 12p13, in head and neck squamous cell carcinomas
2005
Prognostic Value of Loss of Heterozygosity around three Candidate Tumor Suppressor Genes on Chromosome 10q in Astrocytomas
2002
Identification of direct targets for the miR‐17‐92 cluster by proteomic analysis
2011
Detection of codon 61 point mutations of the K-ras gene in lung and colorectal cancers by enriched PCR
2003
Genome-Wide Analyses on Loss of Heterozygosity in Head and Neck Squamous Cell Carcinomas
2003
HD-PTP: A Novel Protein Tyrosine Phosphatase Gene on Human Chromosome 3p21.3
2000
Single nucleotide polymorphism in fibroblast growth factor receptor 4 at codon 388 is associated with prognosis in high‐grade soft tissue sarcoma
2003
Significant growth suppression of synovial sarcomas by the histone deacetylase inhibitor FK228 in vitro and in vivo
2004
A CACNB4 mutation shows that altered Cav2.1 function may be a genetic modifier of severe myoclonic epilepsy in infancy
2008
A Missense Mutation of the Gene Encoding Voltage-Dependent Sodium Channel (Nav1.1) Confers Susceptibility to Febrile Seizures in Rats
2010
Significant correlation of the SCN1A mutations and severe myoclonic epilepsy in infancy
2002
Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers
2002
Decreased expression of the SIN3A gene, a candidate tumor suppressor located at the prevalent allelic loss region 15q23 in non-small cell lung cancer
2007
Telomerase Activity in Gynecologic Tumors
1997
Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas.
2002
Prevalent hyper-methylation of the CDH13 gene promoter in malignant B cell lymphomas
2004
Presence ofEpidermal Growth Factor ReceptorGene T790M Mutation as a Minor Clone in Non–Small Cell Lung Cancer
2006
Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas.
2000
Aberrant Promoter Methylation in Human DAB2 Interactive Protein ( hDAB2IP ) Gene in Breast Cancer
2004
Genetic and epigenetic alterations of BRG1 promote oral cancer development
2005
Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomas
2004
The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains.
1994