Citation Impact
Citing Papers
Fogarty International Center collaborative networks in infectious disease modeling: Lessons learnt in research and capacity building
2018
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
1993 Nature
The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains
1988 StandoutScience
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
The torso receptor protein-tyrosine kinase signaling pathway: An endless story
1993
Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg
1992 StandoutNobel
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Sex, stress and integrity: the importance of MAP kinases in yeast
1994
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
1995 Standout
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
1994
Localized requirement for torso-like expression in follicle cells for development of terminal anlagen of the Drosophila embryo
1990 StandoutNatureNobel
A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation
1994 StandoutNobel
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Drosophila development
1989
The generation of diversity and pattern in animal development
1992 StandoutNobel
Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3
1990 Nature
Heterochronic Genes Control Cell Cycle Progress and Developmental Competence of C. elegans Vulva Precursor Cells
1996 StandoutNobel
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
1993
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
The threonine residues in MAP kinase kinase 1 phosphorylated by MAP kinase in vitro are also phosphorylated in nerve growth factor‐stimulated rat phaeochromocytoma (PC12) cells
1994
The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors
1998 StandoutNobel
Staufen protein associates with the 3′UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner
1994 StandoutNobel
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
Raf functions downstream of Rasl in the Sevenless signal transduction pathway
1992 Nature
Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila
1991 StandoutNobel
Characterization of a putative molluscan insulin-related peptide receptor
1995
Activin signalling and response to a morphogen gradient
1994 StandoutNatureNobel
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
1994 Standout
Genetics of signal transduction in invertebrates
1994
Requirement of the Drosophila raf homologue for torso function
1989 Nature
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways
1994
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
Neuroligin 1: A splice site-specific ligand for β-neurexins
1995 StandoutNobel
The immune response of Drosophila
2003 StandoutNatureNobel
Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis
1993 StandoutNobel
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site
2017 StandoutNobel
The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development
1992 StandoutNobel
A Role for the Segment Polarity Gene shaggy/GSK-3 in the Drosophila Circadian Clock
2001 StandoutNobel
The Drosophila gene torso encodes a putative receptor tyrosine kinase
1989 StandoutNatureNobel
The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos
1992 StandoutNobel
bottleneck acts as a regulator of the microfilament network governing cellularization of the Drosophila embryo
1993 StandoutNobel
A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo
1989 StandoutNobel
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs
1994 StandoutNatureNobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
1989 StandoutNatureNobel
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy
2016
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso
1992
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
1994 Nature
Hidden Markov models of biological primary sequence information.
1994 StandoutNobel
Coping with Protein Quality Control Failure
2017
Identification of fuz7, a Ustilago maydis MEK/MAPKK homolog required for a-locus-dependent and -independent steps in the fungal life cycle.
1994
The egg came first, of course!
1989
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
bicoid and the terminal system activate tailless expression in the early Drosophila embryo
1992
Drosophila neurotactin, a surface glycoprotein with homology to serine esterases, is dynamically expressed during embryogenesis
1990
Localized surface activity of torso, a receptor tyrosine kinase, specifies terminal body pattern in Drosophila.
1989
lin-25, a gene required for vulval induction in Caenorhabditis elegans.
1995
β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family
1989 StandoutScienceNobel
A temperature-sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases.
1994
The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential.
1995
Essential role of β-adrenergic receptor kinase 1 in cardiac development and function
1996 StandoutNobel
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Neural Science
2000 StandoutNobel
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.
1993 Nobel
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.
1990
MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events.
1995
Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII.
1994 Nobel
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1995 StandoutNobel
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Signal transduction via the MAP kinases: proceed at your own RSK.
1993 Standout
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
A thousand and one protein kinases
1987
Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro.
1993
Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins.
1989 StandoutNobel
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.
1989 StandoutNobel
The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK.
1995 StandoutNobel
Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.
1994
Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1.
1994
Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo
1994 StandoutNatureNobel
Works of Mami Hata being referenced
The Genesis and Spread of Reassortment Human Influenza A/H3N2 Viruses Conferring Adamantane Resistance
2007
A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila
1993
Chaperones Hsp70 and Hsp40 Suppress Aggregate Formation and Apoptosis in Cultured Neuronal Cells Expressing Truncated Androgen Receptor Protein with Expanded Polyglutamine Tract
2000
Cloning of a drosophila cDNA encoding a polypeptide similar to the human insulin receptor precursor
1986
Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene.
1988