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Citing Papers
The Caenorhabditis elegans vulval morphogenesis gene sqv - 4 encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated
2002 StandoutNobel
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation
2003 StandoutNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Biology of the Syndecans: A Family of Transmembrane Heparan Sulfate Proteoglycans
1992
Respiratory Syncytial Virus with the Fusion Protein as Its only Viral Glycoprotein Is Less Dependent on Cellular Glycosaminoglycans for Attachment than Complete Virus
2002
Interaction of HIV-1 Tat Protein with Heparin
1997
Defining the Interleukin-8-binding Domain of Heparan Sulfate
1998
Regulated Diversity of Heparan Sulfate
1998
Endothelial Heparan Sulfate Proteoglycan. I. Inhibitory Effects on Smooth Muscle Cell Proliferation
1990
Interstitial Dendritic Cell Guidance by Haptotactic Chemokine Gradients
2013 Science
Domain Structure of Heparan Sulfates from Bovine Organs
1996
Developmental changes in heparan sulfate expression: in situ detection with mAbs.
1992
Presence of unsulfated heparan chains on the heparan sulfate proteoglycan of human colon carcinoma cells
1989
An Animal Cell Mutant Defective in Heparan Sulfate Hexuronic Acid 2- -Sulfation
1996
Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes.
1993
Interaction of Heparan Sulfate from Mammary Cells with Acidic Fibroblast Growth Factor (FGF) and Basic FGF
1998
Sulfotransferases and sulfated oligosaccharides
2002
Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes.
1996
Rat mesangial cells in vitro synthesize a spectrum of proteoglycan species including those of the basement membrane and interstitium
1995
Hallmarks of Cancer: The Next Generation
2011 Standout
Syndecans: multifunctional cell-surface co-receptors
1997
Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor.
1994
Distribution and substrate properties of agrin, a heparan sulfate proteoglycan of developing axonal pathways
1997
Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans.
1992
A rapid quantitative assay for the detection of mammalian heparanase activity
1997
Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis
1988 Nature
Herpes Simplex Virus Types 1 and 2 Differ in Their Interaction with Heparan Sulfate
2000
Sulfated Oligosaccharides Promote Hepatocyte Growth Factor Association and Govern Its Mitogenic Activity
1995
Molecular Cloning and Expression of a Third Member of the Heparan Sulfate/Heparin GlcNAcN-Deacetylase/N-Sulfotransferase Family
1999
Agrin Is a Heparan Sulfate Proteoglycan
1995
Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns.
1994
Binding of heparan sulfate to Staphylococcus aureus
1992
Syndecan proteoglycans and cell adhesion
1998
Structural Modification of Fibroblast Growth Factor-binding Heparan Sulfate at a Determinative Stage of Neural Development
1998
Interaction of Lipoproteins with Heparan Sulfate Proteoglycans and with Lipoprotein Lipase. Studies by Surface Plasmon Resonance Technique
1997
Neurite Outgrowth in Brain Neurons Induced by Heparin-binding Growth-associated Molecule (HB-GAM) Depends on the Specific Interaction of HB-GAM with Heparan Sulfate at the Cell Surface
1996
Differential expression of proteoglycans on the surface of human melanoma cells characterized by altered experimental metastatic potential.
1992
Characterization of Heparin and Heparan Sulfate Domains Binding to the Long Splice Variant of Platelet-derived Growth Factor A Chain
1997
Preparation and structure of heparin lyase-derived heparan sulfate oligosaccharides
1997
Heparin-Protein Interactions
2002 Standout
Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis
1994
Amyloidosis
1994
Dermatan sulphate is released by proteinases of common pathogenic bacteria and inactivates antibacterial α‐defensin
2001
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteins
1998
Chemical Technologies for Probing Glycans
2006 StandoutNobel
Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2
1998
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
The link proteins
1993
Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase
1998
Endothelial Heparan Sulfate Proteoglycans That Bind to L-Selectin Have Glucosamine Residues with Unsubstituted Amino Groups
1995
Heparin and heparan sulfate: structure and function
2002
Sulfatases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
Heparin Dodecasaccharide Binding to Platelet Factor-4 and Growth-related Protein-α
1999
Serine Phosphorylation of Syndecan-2 Proteoglycan Cytoplasmic Domain
1997
Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor
2019
Antibody-based assay for N-deacetylase activity of heparan sulfate/heparin N-deacetylase/N-sulfotransferase (NDST): novel characteristics of NDST-1 and -2
2002
Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma
2012
Atomic structures of amyloid cross-β spines reveal varied steric zippers
2007 StandoutNature
Heparan Sulfate Proteoglycans as Adhesive and Anti-invasive Molecules
1998
Common core structure of amyloid fibrils by synchrotron X-ray diffraction 1 1Edited by F. E. Cohen
1997
Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements
2010 StandoutNobel
The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro.
1997
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Specific Binding of the Chemokine Platelet Factor 4 to Heparan Sulfate
1997
Further characterization of the binding of human recombinant interleukin 2 to heparin and identification of putative binding sites
1998
Isolation and characterization of heparan sulfate from crude porcine intestinal mucosal peptidoglycan heparin
1995
Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells
2008
TGFβ functionalized starPEG-heparin hydrogels modulate human dermal fibroblast growth and differentiation
2015
Cartilage proteoglycans: Structure and potential functions
1994
Specificity studies on the heparin lyases from Flavobacterium heparinum
1993
Multimerization of the Cytoplasmic Domain of Syndecan-4 Is Required for Its Ability to Activate Protein Kinase C
1997
Structure of the cross-β spine of amyloid-like fibrils
2005 StandoutNature
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Sulfotransferases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
Molecular interactions of the syndecan core proteins
1998
Protein folding and misfolding
2003 StandoutNature
Specificities of heparan sulphate proteoglycans in developmental processes
2000 Nature
Enzymatic Modification of Heparan Sulfate on a Biochip Promotes Its Interaction with Antithrombin III
2000
Ligation of Cell Surface Heparan Sulfate Proteoglycans by Antibody-Coated Beads Stimulates Phagocytic Uptake into Epithelial Cells: A Model for Cellular Invasion byNeisseria gonorrhoeae
1998
Autologous Chemotaxis as a Mechanism of Tumor Cell Homing to Lymphatics via Interstitial Flow and Autocrine CCR7 Signaling
2007
Remodelling the extracellular matrix in development and disease
2014 Standout
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall
2003
The pathogenic basis of malaria
2002 StandoutNature
Multiple Interactions of HIV-I Tat Protein with Size-defined Heparin Oligosaccharides
1999
Targeting the tumor and its microenvironment by a dual-function decoy Met receptor
2004
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Nature of the interaction of heparin with acidic fibroblast growth factor
1993
CASK Functions as a Mg2+-Independent Neurexin Kinase
2008 StandoutNobel
Interaction of heparin with annexin V
1999
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo
1998 StandoutNobel
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Heparin Binding and Augmentation of C1 Inhibitor Activity
1999
Solution Structure of the Link Module: A Hyaluronan-Binding Domain Involved in Extracellular Matrix Stability and Cell Migration
1996
The Putative Tumor Suppressors EXT1 and EXT2 Are Glycosyltransferases Required for the Biosynthesis of Heparan Sulfate
1998
A new class of membrane-bound chemokine with a CX3C motif
1997 StandoutNature
Liver Regeneration after Partial Hepatectomy
2009
Pericytes regulate the blood–brain barrier
2010 StandoutNature
Cancer-related inflammation
2008 StandoutNature
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
2003
Enhanced bacterial virulence through exploitation of host glycosaminoglycans
2002
FGFs, heparan sulfate and FGFRs: complex interactions essential for development
2000
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007 StandoutNature
Structural basis for sialic acid–mediated self-recognition by complement factor H
2014
A novel T. cruzi heparin-binding protein promotes fibroblast adhesion and penetration of engineered bacteria and trypanosomes into mammalian cells
1991
Dermatan Sulfate Released after Injury Is a Potent Promoter of Fibroblast Growth Factor-2 Function
1998
Ion mobility–mass spectrometry
2008
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors
2015 StandoutNobel
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
A Genetic Approach to Mammalian Glycan Function
2003
Allosteric inhibition of complement function by a staphylococcal immune evasion protein
2010
Expression of chemokines on the surface of different human endothelia
2005
Regulation of Neurotrophin-3 Expression by Epithelial-Mesenchymal Interactions: The Role of Wnt Factors
1999 StandoutScienceNobel
Heparan Sulfate Biosynthesis
2012
Advances in engineering hydrogels
2017 StandoutScience
The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development
2002 StandoutNobel
Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
1998
Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8.
1993
Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior.
1994
THE GREEN FLUORESCENT PROTEIN
1998 StandoutNobel
Lymphocyte Homing and Homeostasis
1996 StandoutScience
Biosynthesis of heparin. The d -glucuronosyl- and N-acetyl-d -glucosaminyltransferase reactions and their relation to polymer modification
1992
Development of an Ion Mobility Quadrupole Time of Flight Mass Spectrometer
2008 StandoutNobel
Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.
1992
NMR solution conformation of heparin-derived hexasaccharide
1997
SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose
2001 StandoutNobel
Conformational equilibria of α-L-iduronate residues in disaccharides derived from heparin
1987
Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains.
1994
Biosynthesis of heparin. O-sulfation of D-glucuronic acid units.
1990
Glycosaminoglycans Interact Selectively with Chemokines and Modulate Receptor Binding and Cellular Responses
1999
NMR solution conformation of heparin-derived tetrasaccharide
1996
Heparan sulfate: a piece of information
1996
Order Out of Chaos: Assembly of Ligand Binding Sites in Heparan Sulfate
2002
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syndecan-1
1996
The Complex Effects of Heparins on Cancer Progression and Metastasis in Experimental Studies
2001
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Malaria sporozoites and circumsporozoite proteins bind specifically to sulfated glycoconjugates
1992
Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component.
1994
Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the beta 1 integrin subunit.
1991
Infection of Human Dendritic Cells by Dengue Virus Causes Cell Maturation and Cytokine Production
2001
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Angiogenesis
2006
Differential binding of chemokines to glycosaminoglycan subpopulations
1994
Syndecan-1 mediates cell spreading in transfected human lymphoblastoid (Raji) cells.
1996
Imaging the glycome
2008 StandoutNobel
Phosphorylation of a membrane-intercalated proteoglycan, syndecan-2, expressed in a stroma-inducing clone from a mouse Lewis lung carcinoma
1996
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Drosophila syndecan: conservation of a cell-surface heparan sulfate proteoglycan.
1994
MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function
1998 Standout
Microbial adherence to and invasion through proteoglycans
1997
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Binding of Sindbis Virus to Cell Surface Heparan Sulfate
1998
Characterization of Hepatitis C Virus Interaction with Heparan Sulfate Proteoglycans
2015
Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin
1992 StandoutScienceNobel
Functions of Cell Surface Heparan Sulfate Proteoglycans
1999 Standout
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Differential expression of transmembrane proteoglycans in vascular smooth muscle cells.
1993
Vitronectin binds to the gonococcal adhesin OpaA through a glycosaminoglycan molecular bridge
1998
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Purification of rat liver N-heparan-sulfate sulfotransferase.
1988
Radiation to Stromal Fibroblasts Increases Invasiveness of Pancreatic Cancer Cells through Tumor-Stromal Interactions
2004
Works of Malcolm Lyon being referenced
The Interaction of the Transforming Growth Factor-βs with Heparin/Heparan Sulfate Is Isoform-specific
1997
Structure and function of heparan sulphate proteoglycans
1986
Liver heparan sulfate structure. A novel molecular design
1994
Isolation and characterization of the integral glycosaminoglycan constituents of human amyloid A and monoclonal light-chain amyloid fibrils
1991
Identification of an extended N-acetylated sequence adjacent to the protein-linkage region of fibroblast heparan sulphate
1987
Heparan Sulfate Undergoes Specific Structural Changes during the Progression from Human Colon Adenoma to Carcinoma in Vitro
1998
Purification and partial characterization of the major cell-associated heparan sulphate proteoglycan of rat liver
1991
Fibroblast Growth Factor-2 Stimulation of p42/44MAPKPhosphorylation and IκB Degradation Is Regulated by Heparan Sulfate/Heparin in Rat Mammary Fibroblasts
2000
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1
2006
Insights into the Structure/Function of Hepatocyte Growth Factor/Scatter Factor from Studies with Individual Domains
2007
Heparan sulphate-degrading endoglycosidase in liver plasma membranes
1988
Hepatocyte growth factor/scatter factor: a heparan sulphate-binding pleiotropic growth factor
1994
The Heparin/Heparan Sulfate Sequence That Interacts with Cyclophilin B Contains a 3-O-Sulfated N-Unsubstituted Glucosamine Residue
2007
Patterns of sulphation in heparan sulphate: Polymorphism based on a common structural theme
1992
Elucidation of the Structural Features of Heparan Sulfate Important for Interaction with the Hep-2 Domain of Fibronectin
2000
Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion
1998
The Mode of Action of Heparan and Dermatan Sulfates in the Regulation of Hepatocyte Growth Factor/Scatter Factor
2002
Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen‐activated protein kinase and phosphatidylinositol 3‐kinase/Akt pathways
2001
The Molecular Phenotype of Heparan Sulfate in theHs2st−/− Mutant Mouse
2001
Highly Sensitive Sequencing of the Sulfated Domains of Heparan Sulfate
1999
Disease-associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-dimensional Structure
2006
Proteoglycans: Pericellular and Cell Surface Multireceptors that Integrate External Stimuli in the Mammary Gland
2001
Hepatocyte Growth Factor/Scatter Factor Binds with High Affinity to Dermatan Sulfate
1998
Conformation of glycosaminoglycans by ion mobility mass spectrometry and molecular modelling
2005
Heparan Sulphate Proteoglycans: Molecular Organisation of Membrane-Associated Species and an Approach to Polysaccharide Sequence Analysis
1992
Specific chemical modifications of link protein and their effect on binding to hyaluronate and cartilage proteoglycan
1986
Molecular cloning of the major cell surface heparan sulfate proteoglycan from rat liver.
1992
Sulphated proteoglycan is required for collecting duct growth and branching but not nephron formation during kidney development
1995
Heparan sulphate proteoglycans
1990
Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants
1994
A study of equilibrium binding of link protein to hyaluronate
1983
Binding of endostatin to endothelial heparan sulphate shows a differential requirement for specific sulphates
2003