Citation Impact
Citing Papers
Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity
2011
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
2013 StandoutScience
Asc and Ipaf Inflammasomes Direct Distinct Pathways for Caspase-1 Activation in Response to Legionella pneumophila
2009
Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
2013 Science
K+ Efflux Agonists Induce NLRP3 Inflammasome Activation Independently of Ca2+ Signaling
2015
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
Current knowledge on exosome biogenesis and release
2017 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation
2016
Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents
2013
Inhibition of Anthrax Lethal Toxin-Induced Cytolysis of RAW264.7 Cells by Celastrol
2008
Suppression of the pro-inflammatory NLRP3/interleukin-1β pathway in macrophages by the thioredoxin reductase inhibitor auranofin
2014
Necroptosis and its role in inflammation
2015 StandoutNature
Mechanisms of NOD-like Receptor-Associated Inflammasome Activation
2013
Mechanisms of interleukin-1β release
2009
Proteolytic Processing of Nlrp1b Is Required for Inflammasome Activity
2012
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens
2006 Standout
Brain-immune interactions and disease susceptibility
2005
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes
2014
Activation and regulation of the inflammasomes
2013 Standout
Anthrax Toxin Receptor 2–Dependent Lethal Toxin Killing In Vivo
2006
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
2017
Proteasomes Control Caspase-1 Activation in Anthrax Lethal Toxin-mediated Cell Killing
2007
Biogenesis and secretion of exosomes
2014
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Targeting the NLRP3 inflammasome in inflammatory diseases
2018
Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax Lethal Toxin
2008
Mechanisms of inflammasome activation: recent advances and novel insights
2015
Direct Proteolytic Cleavage of NLRP1B Is Necessary and Sufficient for Inflammasome Activation by Anthrax Lethal Factor
2013
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Regulation of inflammasome signaling
2012
Noncanonical Inflammasomes: Caspase-11 Activation and Effector Mechanisms
2013
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation
2014
Proresolution Lipid Mediators in Multiple Sclerosis — Differential, Disease Severity-Dependent Synthesis — A Clinical Pilot Trial
2013
A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome
2018
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
Pyroptosis: host cell death and inflammation
2009 Standout
TRPM2 links oxidative stress to NLRP3 inflammasome activation
2013
Molecular Mechanism of NLRP3 Inflammasome Activation
2010
The NAIP/NLRC4 inflammasomes
2015
The Inflammasomes
2010 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
Bacterial pore-forming toxins: The (w)hole story?
2007
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Function of Nod‐like receptors in microbial recognition and host defense
2008
High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells
2014 Nature
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
2010 Standout
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis
2013
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Diverse mechanisms for inflammasome sensing of cytosolic bacteria and bacterial virulence
2015
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Inflammasomes and Metabolic Disorders: Old Genes in Modern Diseases
2014
Human Monocytes Engage an Alternative Inflammasome Pathway
2016
NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells
2012
Inflammasomes in health and disease
2012 StandoutNature
Genetic Loss of Murine Pyrin, the Familial Mediterranean Fever Protein, Increases Interleukin-1β Levels
2012
An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology
2013
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
2008
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
2016 Standout
The NLRP3 Inflammasome: A Sensor for Metabolic Danger?
2010 Science
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function
2014
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Pyroptotic cell death defends against intracellular pathogens
2015
Screening Blockers Against a Potassium Channel with a Droplet Interface Bilayer Array
2008
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Caspase-11 Protects Against Bacteria That Escape the Vacuole
2013 Science
NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii
2013
Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin
2015
Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders
2017
Mechanisms associated with biogenesis of exosomes in cancer
2019
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
The Inflammasomes: Guardians of the Body
2009 Standout
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
The NLRP 1 inflammasomes
2015
Anthrolysin O and Other Gram-positive Cytolysins Are Toll-like Receptor 4 Agonists
2004
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
The NAIP –NLRC 4 inflammasome in innate immune detection of bacterial flagellin and type III secretion apparatus
2015
Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes
2016
Inflammasomes and Their Roles in Health and Disease
2012
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
2014 Standout
Cutting Edge: Resistance to Bacillus anthracis Infection Mediated by a Lethal Toxin Sensitive Allele of Nalp1b/Nlrp1b
2009
NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice
2012
Multiple Cathepsins Promote Pro–IL-1β Synthesis and NLRP3-Mediated IL-1β Activation
2015
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Recognition of Bacteria by Inflammasomes
2012
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Mahtab Moayeri being referenced
Blocking anthrax lethal toxin at the protective antigen channel by using structure-inspired drug design
2005
Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo
2009
Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin
2013
Anthrax lethal toxin activates the inflammasome in sensitive rat macrophages
2010
Anthrax Toxin Targeting of Myeloid Cells through the CMG2 Receptor Is Essential for Establishment of Bacillus anthracis Infections in Mice
2010
Anthrax Lethal Factor Cleaves Mouse Nlrp1b in Both Toxin-Sensitive and Toxin-Resistant Macrophages
2012
Bacterial Exotoxins and the Inflammasome
2015
Killing of macrophages by anthrax lethal toxin: involvement of the N-end rule pathway
2008
The roles of anthrax toxin in pathogenesis
2003
Anthrax and the inflammasome
2011
Key tissue targets responsible for anthrax-toxin-induced lethality
2013 Nature
Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii
2014
Transcriptional analysis of the three Nlrp1 paralogs in mice
2013
Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
2012 Nature
Cellular and systemic effects of anthrax lethal toxin and edema toxin
2009
Anthrax lethal and edema toxins in anthrax pathogenesis
2014
Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome
2012
Bacillus anthracis Edema Toxin Causes Extensive Tissue Lesions and Rapid Lethality in Mice
2005
Matrix Metalloproteinase-activated Anthrax Lethal Toxin Demonstrates High Potency in Targeting Tumor Vasculature
2007
Inflammasome Sensor Nlrp1b-Dependent Resistance to Anthrax Is Mediated by Caspase-1, IL-1 Signaling and Neutrophil Recruitment
2010
Role of N-Terminal Amino Acids in the Potency of Anthrax Lethal Factor
2008
Efficient Neutralization of Anthrax Toxin by Chimpanzee Monoclonal Antibodies against Protective Antigen
2006
Bacillus anthracis lethal toxin induces TNF-α–independent hypoxia-mediated toxicity in mice
2003
Susceptibility to Anthrax Lethal Toxin-Induced Rat Death Is Controlled by a Single Chromosome 10 Locus That Includes rNlrp1
2010
Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome
2007
The Cyclopentenone Prostaglandin 15d-PGJ2 Inhibits the NLRP1 and NLRP3 Inflammasomes
2015
CA-074Me Protection against Anthrax Lethal Toxin
2009
Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii
2014
Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism
2015
Mouse Susceptibility to Anthrax Lethal Toxin Is Influenced by Genetic Factors in Addition to Those Controlling Macrophage Sensitivity
2004
Anthrax Lethal Toxin Induces Ketotifen-Sensitive Intradermal Vascular Leakage in Certain Inbred Mice
2006
Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection
2011
Auranofin Protects against Anthrax Lethal Toxin-Induced Activation of the Nlrp1b Inflammasome
2010
Endocrine Perturbation Increases Susceptibility of Mice to Anthrax Lethal Toxin
2005
Small-Molecule Inhibitors of Lethal Factor Protease Activity Protect against Anthrax Infection
2013
Anthrax lethal factor represses glucocorticoid and progesterone receptor activity
2003
Oxidized ATP Protection against Anthrax Lethal Toxin
2006