Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
V600E BRAF is associated with disabled feedback inhibition of RAF–MEK signaling and elevated transcriptional output of the pathway
2009
Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1–Positive Cancer Stem Cells
2010
Clinical, Pathologic, and Biologic Features Associated with BRAF Mutations in Non–Small Cell Lung Cancer
2013
Development of siRNA Payloads to Target KRAS -Mutant Cancer
2014
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling
2015
DICER1 hotspot mutations in non-epithelial gonadal tumours
2013
Schizophrenia risk from complex variation of complement component 4
2016 StandoutNature
Hallmarks of Cancer: The Next Generation
2011 Standout
Shortening of 3′UTRs Correlates with Poor Prognosis in Breast and Lung Cancer
2012
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
The PI3K/AKT Pathway as a Target for Cancer Treatment
2015
Oncogenic KRAS signalling in pancreatic cancer
2014
let-7 microRNAs in development, stem cells and cancer
2008
The role of let-7 in cell differentiation and cancer
2009
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
K-ras Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer
2008 Standout
Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis
2006
A view on drug resistance in cancer
2019 StandoutNature
Analysis of the genome to personalize therapy for melanoma
2010
MicroRNA Functions in Stress Responses
2010
MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer
2009
Wnt/β-catenin pathway represses let-7 microRNAs expression via transactivation of Lin28 to augment breast cancer stem cell expansion
2013
Guilty as charged
2004
Regulating the regulators: mechanisms controlling the maturation of microRNAs
2008
Regulation of microRNA biogenesis
2014 Standout
Targeting microRNAs in cancer: rationale, strategies and challenges
2010
Innate and adaptive immune cells in the tumor microenvironment
2013 Standout
Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS
2005
The biology and management of non-small cell lung cancer
2018 StandoutNature
MicroRNA regulation by RNA-binding proteins and its implications for cancer
2011
Yeasts encoding tumour antigens in cancer immunotherapy
2005
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
The microcosmos of cancer
2012 Nature
Roles for MicroRNAs in Conferring Robustness to Biological Processes
2012
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
Lung Cancer
2008 Standout
A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors
2007
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs
2010 Nature
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
MicroRNA sponges: Progress and possibilities
2010
Genetic variation in microRNA networks: the implications for cancer research
2010
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications
2009
A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
2011 Standout
Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer
2014
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis
2010
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Sequence features associated with microRNA strand selection in humans and flies
2009
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
Global microRNA elevation by inducible Exportin 5 regulates cell cycle entry
2013
Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
2004 Standout
Extending the phenotypes associated withDICER1mutations
2011
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
2011 StandoutNature
Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts
2013
C-Raf Inhibits MAPK Activation and Transformation by B-RafV600E
2009
A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells
2010
The Lin28/let-7 Axis Regulates Glucose Metabolism
2011
Microrna Let-7: An Emerging Next-Generation Cancer Therapeutic
2010
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
The use of miRNA microarrays for the analysis of cancer samples with global miRNA decrease
2013
Suppression of lung adenocarcinoma progression by Nkx2-1
2011 Nature
Regression of murine lung tumors by the let-7 microRNA
2009
Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
2006
High BRAF mutation frequency does not characterize all melanocytic tumor types
2004
An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation
2009
An elegant miRror: microRNAs in stem cells, developmental timing and cancer
2009
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
2008 StandoutNature
Natural RNA circles function as efficient microRNA sponges
2013 StandoutNature
An efficient and sensitive method for preparing cDNA libraries from scarce biological samples
2014 StandoutNobel
MicroRNA biogenesis pathways in cancer
2015 Standout
Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours
2014
A MicroRNA Targeting Dicer for Metastasis Control
2010
Mutations in Conserved Residues of the C. elegans microRNA Argonaute ALG-1 Identify Separable Functions in ALG-1 miRISC Loading and Target Repression
2014 StandoutNobel
A TARBP2-Dependent miRNA Expression Profile Underlies Cancer Stem Cell Properties and Provides Candidate Therapeutic Reagents in Ewing Sarcoma
2012
Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas
2003
In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma
2011
Mechanisms of resistance to therapies targeting BRCA-mutant cancers
2013
BRAF Mutations Are Sufficient to Promote Nevi Formation and Cooperate with p53 in the Genesis of Melanoma
2005
Roles of small RNAs in tumor formation
2010
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
EMT: 2016
2016 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
MicroRNAs and Cancer: Short RNAs Go a Long Way
2009
Determinants of MicroRNA Processing Inhibition by the Developmentally Regulated RNA-binding Protein Lin28
2008
Generation of miRNA sponge constructs
2012
MicroRNAs in Human Cancer
2012
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER
2014
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
AKT/PKB Signaling: Navigating the Network
2017 Standout
Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
2010 Standout
Synthetic lethal therapies for cancer: what’s next after PARP inhibitors?
2018
BRAF mutation predicts sensitivity to MEK inhibition
2005 Nature
Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas
2012
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Loss of Dicer expression is associated with breast cancer progression and recurrence
2012
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
Feedback and redundancy in receptor tyrosine kinase signaling: relevance to cancer therapies
2014
Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
2010
DNA methylomes, histone codes and miRNAs: Tying it all together
2008
DICER1: mutations, microRNAs and mechanisms
2014
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal
2015 StandoutNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
2010
Improving Prospects for Targeting RAS
2015
miRNA Processing and Human Cancer: DICER1 Cuts the Mustard
2011
Cell‐ and developmental stage‐specific Dicer1 ablation in the lung epithelium models cystic pleuropulmonary blastoma
2014
Suppression of BRAF(V599E) in human melanoma abrogates transformation.
2003
mir-276a strengthens Drosophila circadian rhythms by regulating timeless expression
2016 StandoutNobel
The novel complement inhibitor human CUB and Sushi multiple domains 1 (CSMD1) protein promotes factor I‐mediated degradation of C4b and C3b and inhibits the membrane attack complex assembly
2013
Recurrent Hemizygous Deletions in Cancers May Optimize Proliferative Potential
2012 Science
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Harboring BRAF Mutations
2011
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Understanding Melanoma Signaling Networks as the Basis for Molecular Targeted Therapy
2009
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Cancer Genome Landscapes
2013 StandoutScience
BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair.
2003
KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment
2016
Genetics and biology of pancreatic ductal adenocarcinoma
2016
Exosomal miRNAs as novel cancer biomarkers: Challenges and opportunities
2018
Genetic classification of oral and oropharyngeal carcinomas identifies subgroups with a different prognosis.
2009
Hypoxia Potentiates MicroRNA-Mediated Gene Silencing through Posttranslational Modification of Argonaute2
2011
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments
2013
Works of Madhu Kumar being referenced
Coordinate Direct Input of Both KRAS and IGF1 Receptor to Activation of PI3 kinase in KRAS -Mutant Lung Cancer
2013
CharacterizationCSMD1in a large set of primary lung, head and neck, breast and skin cancer tissues
2009
Dicer1 functions as a haploinsufficient tumor suppressor
2009
Genome‐Wide Profiling of Oral Squamous Cell Carcinoma by Array‐Based Comparative Genomic Hybridization
2006
The GATA2 Transcriptional Network Is Requisite for RAS Oncogene-Driven Non-Small Cell Lung Cancer
2012
RAS and RHO Families of GTPases Directly Regulate Distinct Phosphoinositide 3-Kinase Isoforms
2013
Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of DICER1
2012
Requirement for Interaction of PI3-Kinase p110α with RAS in Lung Tumor Maintenance
2013
Suppression of non-small cell lung tumor development by the let-7 microRNA family
2008
BRAF and RAS mutations in human lung cancer and melanoma.
2002