Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
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Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
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Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
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Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Functional diversity of helper T lymphocytes
1996 StandoutNature
Transient adhesion of neutrophils to endothelium.
1989
Structure and Function of Leukocyte Integrins
1990
Sputum Biomarkers of Inflammation in Cystic Fibrosis Lung Disease
2007
Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates β-1 Adrenergic Receptor Endocytosis through Different Pathways
2003 StandoutNobel
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
THERAPIES AIMED AT AIRWAY INFLAMMATION IN CYSTIC FIBROSIS
1998
Early pulmonary infection, inflammation, and clinical outcomes in infants with cystic fibrosis*
2001
Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
1991 Standout
The history, properties, and biological effects of cachectin
1988 StandoutNobel
Identification of a highly mobilizable subset of human neutrophil intracellular vesicles that contains tetranectin and latent alkaline phosphatase.
1990
Evidence for a Functional Interaction between Integrins and G Protein-activated Inward Rectifier K+ Channels
1998
Longitudinal Assessment ofPseudomonas aeruginosain Young Children with Cystic Fibrosis
2001
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Physiological and pathological aspects of circulating immune complexes
1989
Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line.
1992
Surface expression of Fc gamma receptor III (CD16) on chemoattractant-stimulated neutrophils is determined by both surface shedding and translocation from intracellular storage compartments.
1992
Regulated portals of entry into the cell
2003 StandoutNature
Cytokine enhancement of complement‐dependent phagocytosis by macrophages: synergy of tumor necrosis factor‐α and granulocyte‐macrophage colony‐stimulating factor for phagocytosis of Cryptococcus neoformans
1992
Recruitment of CD11b/CD18 to the neutrophil surface and adherence-dependent cell locomotion.
1992
The Formation of Ceramide-1-phosphate during Neutrophil Phagocytosis and Its Role in Liposome Fusion
1998 StandoutNobel
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans
2008 StandoutNobel
Exudation induces clustering of CR1 receptors at the surface of human polymorphonuclear leukocytes
1990
Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system
1998
Human neutrophil granules and secretory vesicles
1993
Function and heterogeneity of human Fc receptors for immunoglobulin G.
1989
Management of Pulmonary Disease in Patients with Cystic Fibrosis
1996
Pharmacological approaches for the discovery and development of new anti-inflammatory agents for the treatment of cystic fibrosis
2002
TREM-1 amplifies inflammation and is a crucial mediator of septic shock
2001 StandoutNature
Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part I)
1994
The Leukocyte Integrins
1989
Neutrophilic Leukocyte Granules: From Structure to Function
1993
Processing and targeting of granule proteins in human neutrophils
1999
Aerosol α1 -antitrypsin treatment for cystic fibrosis
1991
An ELISA for grancalcin, a novel cytosolic calcium-binding protein present in leukocytes
1995
Beclomethasone diproprionate reduced airway inflammation without adrenal suppression in young children with cystic fibrosis: A pilot study†‡
2001
Adhesion receptors of the immune system
1990 StandoutNature
Granules and vesicles of human neutrophils. The role of endomembranes as source of plasma membrane proteins
1993
Sputum endothelin-1 is increased in cystic fibrosis and chronic obstructive pulmonary disease
1999
Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor.
1992
Randomised controlled trial of inhaled corticosteroids (fluticasone propionate) in cystic fibrosis
1997
Protease-antiprotease imbalance in the lungs of children with cystic fibrosis.
1994
Enhanced Phagocytosis through Inhibition of de Novo Ceramide Synthesis
2003 StandoutNobel
Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils.
1993
Neutrophils, from Marrow to Microbes
2010 Standout
Induced sputum inflammatory measures correlate with lung function in children with cystic fibrosis
2002
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
Immunologic Aspects of Cystic Fibrosis
1988
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
1994 Standout
Critical role of Vα14+ natural killer T cells in the innate phase of host protection against Streptococcus pneumoniae infection
2003
Two Signaling Mechanisms for Activation of αMβ2 Avidity in Polymorphonuclear Neutrophils
1998
Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation.
1994
Eosinophils: Biology and Role in Disease
1995
Inflammation in cystic fibrosis lung disease: Pathogenesis and therapy
2015
The Role of Inflammation in the Pathophysiology of CF Lung Disease
2002
Destruction and loss of bronchial cartilage in cystic fibrosis
1998
Stimulus-dependent secretion of plasma proteins from human neutrophils.
1992
Solubilization of glycosyl-phosphatidylinositol-anchored proteins in quiescent and stimulated neutrophils
1995
Staphylococcus aureusInfections
1998 Standout
Predominant TH2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma
1992 Standout
The C5a chemoattractant receptor mediates mucosal defence to infection
1996 Nature
Airway Inflammation in Children with Cystic Fibrosis and Healthy Children Assessed by Sputum Induction
2001
Regional Variability of Lung Inflammation in Cystic Fibrosis
1997
Sputum Biomarkers of Inflammation and Lung Function Decline in Children with Cystic Fibrosis
2012
Quantitation of Inflammatory Responses to Bacteria in Young Cystic Fibrosis and Control Patients
1999
Proteinase 3, a Potent Secretagogue in Airways, Is Present in Cystic Fibrosis Sputum
1999
The Interrelationship of Sputum Inflammatory Markers in Patients with Chronic Bronchitis
1999
Lower Airway Inflammation in Infants and Young Children with Cystic Fibrosis
1997
Pathophysiology and Management of Pulmonary Infections in Cystic Fibrosis
2003 Standout
The Effect of Chloride Concentration on Human Neutrophil Functions: Potential Relevance to Cystic Fibrosis
1998
Subepithelial Fibrosis and Degradation of the Bronchial Extracellular Matrix in Cystic Fibrosis
1998
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Inflammatory Response in Airway Epithelial Cells Isolated from Patients with Cystic Fibrosis
2002
Overproduction of the CFTR R Domain Leads to Increased Levels of AsialoGM1 and Increased Pseudomonas aeruginosa Binding by Epithelial Cells
1998
A Phase II, Double-Blind, Randomized, Placebo-Controlled Clinical Trial of tgAAVCF Using Maxillary Sinus Delivery in Patients with Cystic Fibrosis with Antrostomies
2002
Staphylococcus aureus
1984
Pulmonary Outcome in Cystic Fibrosis Is Influenced Primarily by Mucoid Pseudomonas aeruginosa Infection and Immune Status and Only Modestly by Genotype
1999
The Role of Antibody and Complement in the Reticuloendothelial Clearance of Pneumococci from the Bloodstream
1983
Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1.
1991 StandoutNobel
Structural and functional heterogeneity among peroxidase-negative granules in human neutrophils: identification of a distinct gelatinase- containing granule subset by combined immunocytochemistry and subcellular fractionation
1993
Toxic Potential of Materials at the Nanolevel
2006 StandoutScience
Strain variation in phagocytosis of Cryptococcus neoformans: dissociation of susceptibility to phagocytosis from activation and binding of opsonic fragments of C3
1988
Inflammation and its genesis in cystic fibrosis
2015
Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms
2000 StandoutNature
Antibiotic Therapy for Chronic Infection of Pseudomonas in the Lung
1993
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
Disorders of Phagocyte Function
1987
Molecular cloning and nucleotide sequence of the streptavidin gene
1986 StandoutNobel
CR3 (Mac-1, alpha M beta 2, CD11b/CD18) and Fc gamma RIII cooperate in generation of a neutrophil respiratory burst: requirement for Fc gamma RIII and tyrosine phosphorylation.
1994
Central Role of Complement in Passive Protection by Human IgG1 and IgG2 Anti-pneumococcal Antibodies in Mice
2003
The receptor for urokinase-type plasminogen activator and urokinase is translocated from two distinct intracellular compartments to the plasma membrane on stimulation of human neutrophils
1994
Phagocytosis of Microbes: Complexity in Action
2002
Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins.
1989
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
Microsomal and cytosolic fractions of guinea pig hepatocytes contain 100-kilodalton GTP-binding proteins reactive with antisera against alpha subunits of stimulatory and inhibitory heterotrimeric GTP-binding proteins.
1990 StandoutNobel
Constitutive and stimulus-induced phosphorylation of CD11/CD18 leukocyte adhesion molecules.
1989
Allergic Bronchopulmonary Aspergillosis
1999
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Subunit interactions of transcarboxylase as studied by circular dichroism
1982
Adhesomes: specific granules containing receptors for laminin, C3bi/fibrinogen, fibronectin, and vitronectin in human polymorphonuclear leukocytes and monocytes.
1989
Oral Administration of Chitin Down-Regulates Serum IgE Levels and Lung Eosinophilia in the Allergic Mouse
2000
Bacterial Biofilms: A Common Cause of Persistent Infections
1999 StandoutScience
Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection
1996
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
2013 StandoutNobel
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
A rapid fluorescent assay to distinguish attached from phagocytized yeast particles
1987
Prediction of secondary structure for Eco RI endonuclease.
1984 StandoutNobel
Thrombospondin receptor expression in human neutrophils coincides with the release of a subpopulation of specific granules
1992
Mucoid Pseudomonas aeruginosa in cystic fibrosis: characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection
1997
Chemoattractant-Regulated Mobilization of a Novel Intracellular Compartment in Human Neutrophils
1987 Science
Altered respiratory epithelial cell cytokine production in cystic fibrosis
1999
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
Integrin Signaling
1999 StandoutScience
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Selective Covalent Protein Immobilization: Strategies and Applications
2009
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
Granules of the Human Neutrophilic Polymorphonuclear Leukocyte
1997 Standout
Dynamic reorganization of the alkaline phosphatase-containing compartment during chemotactic peptide stimulation of human neutrophils imaged by backscattered electrons
1995
Active Oxygen Species in the Induction of Plant Systemic Acquired Resistance by Salicylic Acid
1993 StandoutScience
Subcellular localization of CD66, CD67, and NCA in human neutrophils
1992
Potential of preventing Pseudomonas aeruginosa lung infections in cystic fibrosis patients: Experimental studies in animals
1996
Human neutrophils are selectively activated by independent ligation of the subunits of the CD11b/CD18 integrin
1994
Neutrophil Extracellular Traps Kill Bacteria
2004 StandoutScience
The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung
2015
Stenotrophomonas maltophilia: an Emerging Global Opportunistic Pathogen
2012 Standout
Biochemistry of C3 and Related Thiolester Proteins in Infection and Inflammation
1987
HOW NEUTROPHILS KILL MICROBES
2005 Standout
Mobilizable intracellular pool of p55 (type I) tumor necrosis factor receptors in human neutrophils
1992
Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells.
1998
γ3 Gene-Disrupted Mice Selectively Deficient in the Dominant IgG Subclass Made to Bacterial Polysaccharides. II. Increased Susceptibility to Fatal Pneumococcal Sepsis Due to Absence of Anti-Polysaccharide IgG3 Is Corrected by Induction of Anti-Polysaccharide IgG1
2002
Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes
2007 StandoutNobel
Intracellular location of T200 and Mo1 glycoproteins in human neutrophils.
1988
Lung Infections Associated with Cystic Fibrosis
2002 Standout
Raman spectroscopy of avidin: secondary structure, disulfide conformation, and the environment of tyrosine
1982
The amino acid sequences of the biotinyl subunit essential for the association of transcarboxylase.
1982 StandoutNobel
Isolation and characterization of gelatinase granules from human neutrophils
1994
The Use of the Avidin‐Biotin Complex as a Tool in Molecular Biology
1980
The Pathogenesis of Sepsis
1991
A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen.
1993
IL-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leucocyte integrin (CD11/18)-dependent manner.
1990
THE CAVEOLAE MEMBRANE SYSTEM
1998 Standout
Subcellular localization of Gi alpha in human neutrophils.
1988
Human neutrophil gelatinase is a component of specific granules.
1989
Monocyte chemoattractant protein-1 gene is expressed in activated neutrophils and retinoic acid-induced human myeloid cell lines
1994
Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils.
1995
Works of Madelyn Berger being referenced
Secretory vesicles are the intracellular reservoir of complement receptor 1 in human neutrophils.
1994
Inflammatory cytokines in cystic fibrosis lungs.
1995
Internalization of type 1 complement receptors and de novo multivesicular body formation during chemoattractant-induced endocytosis in human neutrophils.
1994
Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis.
1995
Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch.
1990
Complement receptor expression on neutrophils at an inflammatory site, the Pseudomonas-infected lung in cystic fibrosis.
1989
Elastin and collagen degradation products in urine of patients with cystic fibrosis.
1995
Enhancement by Tumor Necrosis Factor- of Fc Receptor Expression and IgA-Mediated Superoxide Generation and Killing of Pseudomonas aeruginosa by Polymorphonuclear Leukocytes
1994
Cross-Sectional and Longitudinal Studies of Naturally Occurring Antibodies to Pseudomonas aeruginosa in Cystic Fibrosis Indicate Absence of Antibody-Mediated Protection and Decline in Opsonic Quality after Infection
1995
Functional differences between the 40 kDa and 50 to 70 kDa IgG Fc receptors on human neutrophils revealed by elastase treatment and antireceptor antibodies.
1988
Intracellular sites for storage and recycling of C3b receptors in human neutrophils.
1991
IgE antibodies to Staphylococcus aureus and Candida albicans in patients with the syndrome of hyperimmunoglobulin E and recurrent infections.
1980
Tumor necrosis factor is the major monocyte product that increases complement receptor expression on mature human neutrophils
1988
Purification of the subunits of transcarboxylase by affinity chromatography on avidin-sepharose.
1975
Calcium requirements for increased complement receptor expression during neutrophil activation.
1985
Increased expression of complement decay-accelerating factor during activation of human neutrophils.
1987
A quantitative analysis of C3 binding to O-antigen capsule, lipopolysaccharide, and outer membrane protein of E. coli 0111B4.
1984
Intracellular degradation of the complement C3b/C4b receptor in the absence of ligand.
1988
Human neutrophils increase expression of C3bi as well as C3b receptors upon activation.
1984
Tumor necrosis factor is the major monocyte product that increases complement receptor expression on mature human neutrophils
1988
Localization of complement component 3 on Streptococcus pneumoniae: anti-capsular antibody causes complement deposition on the pneumococcal capsule
1983