Citation Impact
Citing Papers
A gene atlas of the mouse and human protein-encoding transcriptomes
2004 Standout
Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
2008 Standout
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
2010 StandoutScience
The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice
2009
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
2011 StandoutNobel
Hypoxia, a Novel Inducer of Acute Phase Gene Expression in a Human Hepatoma Cell Line
1995
Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
2010
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
EGFR Antagonists in Cancer Treatment
2008 Standout
TNF and EPO: major players in the innate immune response: their discovery
2012
Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1
2000 StandoutNobel
K-ras Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer
2008 Standout
Erythropoietin processing in erythropoietic system and central nervous system
1995
Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death
1996
Insulin Stimulates Hypoxia-inducible Factor 1 through a Phosphatidylinositol 3-Kinase/Target of Rapamycin-dependent Signaling Pathway
2002 StandoutNobel
Hypoxia-Inducible Erythropoietin Signaling in Squamous Dysplasia and Squamous Cell Carcinoma of the Uterine Cervix and Its Potential Role in Cervical Carcinogenesis and Tumor Progression
2003
Sites of erythropoietin production
1997 StandoutNobel
Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer
2009 Standout
Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex‐Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods
2009 StandoutNobel
The Hallmarks of Cancer
2000 Standout
The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells
1989 StandoutNature
Protein glycosylation
1993
Synergistic enhancement of EGF, but not HGF, stimulated hepatocyte motility by TGF-β1 in vitro
1997
Erythropoietin Gene Expression in Human, Monkey and Murine Brain
1996
Oncogenes as inducers of tumor angiogenesis
1995
Increased plasma viscosity as a reason for inappropriate erythropoietin formation.
1993 StandoutNobel
Diabetic Retinopathy
2012 Standout
HIF hydroxylation and the mammalian oxygen-sensing pathway
2003 StandoutNobel
Erythropoietin regulates tumour growth of human malignancies
2003
Erythropoietin as a Retinal Angiogenic Factor in Proliferative Diabetic Retinopathy
2005
Production and ligand-binding characteristics of the soluble form of murine erythropoietin receptor
1992
Selective in vitro glycosylation of recombinant proteins: semi-synthesis of novel homogeneous glycoforms of human erythropoietin
2001 StandoutNobel
Application of cell encapsulation for controlled delivery of biological therapeutics
2013
Selection of Mutant CHO Cells with Constitutive Activation of the HIF System and Inactivation of the von Hippel-Lindau Tumor Suppressor
2001 StandoutNobel
Antifibrogenic effect of a deletion variant of hepatocyte growth factor on liver fibrosis in rats
1996
Erythropoietin and Erythropoietin Receptor
1999
Tissue distribution of erythropoietin and erythropoietin receptor in the developing human fetus
1998
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Regulation of the Erythropoietin Gene
1989
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Insulin-like growth factors and insulin stimulate erythropoietin production in primary cultured astrocytes
1997
Artificial human Met agonists based on macrocycle scaffolds
2015
The role of carbohydrate in recombinant human erythropoietin
1990
Angiogenesis as a therapeutic target
2005 StandoutNature
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Anemia of Chronic Disease
2005 Standout
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
Erythropoietin structure-function relationships. Mutant proteins that test a model of tertiary structure
1993
Antifibrogenic Effect of A Deletion Variant of Hepatocyte Growth Factor on Liver Fibrosis in Rats
1996
Anti-erythropoietin receptor monoclonal antibody: epitope mapping, quantification of the soluble receptor, and detection of the solubilized transmembrane receptor and the receptor-expressing cells
1996
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
2015 StandoutNobel
A Strategy for the Chemoselective Synthesis of O-Linked Glycopeptides with Native Sugar−Peptide Linkages
1997 StandoutNobel
Erythropoietin and erythropoietin receptors in the peripheral nervous system: changes after nerve injury
2001
Integration of Oxygen Signaling at the Consensus HRE
2005
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Localization of specific erythropoietin binding sites in defined areas of the mouse brain.
1995
Renal erythropoietin: Properties and production
2006
Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.
1995
Hypoxia-Inducible Factor-1α Mediates Hypoxia-Induced Delayed Neuronal Death That Involves p53
1999
Ovarian Cancer
2008
HIF hydroxylation and the mammalian oxygen-sensing pathway
2003 StandoutNobel
Erythropoietin enhancer stimulates production of a recombinant protein by Chinese hamster ovary (CHO) cells under hypoxic condition
1997
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
Locus control regions
2002
PROLINE HYDROXYLATION AND GENE EXPRESSION
2005 StandoutNobel
Embryonal Carcinoma P19 Cells Produce Erythropoietin Constitutively But Express Lactate Dehydrogenase in an Oxygen-Dependent Manner
1998 StandoutNobel
Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model.
2002
Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress
2001
Erythropoietin Is a Paracrine Mediator of Ischemic Tolerance in the Brain: Evidence from anIn VitroModel
2002
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.
1992 StandoutNobel
Production of Recombinant Human Erythropoietin in Mammalian Cells: Host–Cell Dependency of the Biological Activity of the Cloned Glycoprotein
1988
Structural characterization of human erythropoietin.
1986
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
1998 Standout
Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice.
1991 StandoutNobel
Coexpression of Erythropoietin and Vascular Endothelial Growth Factor in Nervous System Tumors Associated With von Hippel-Lindau Tumor Suppressor Gene Loss of Function
1998
Improvement of enzyme activity, stability and selectivity via immobilization techniques
2007 Standout
Hearts From Rodents Exposed to Intermittent Hypoxia or Erythropoietin Are Protected Against Ischemia-Reperfusion Injury
2003 StandoutNobel
Chemoselective Approaches to Glycoprotein Assembly
2001 StandoutNobel
Liver Regeneration
1997 StandoutScience
Hypoxia-Induced Stroke Tolerance in the Mouse Is Mediated by Erythropoietin
2003
Regulation of the Erythropoietin Gene
1999
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
1999 StandoutNobel
Protection from Oxidative Stress–Induced Apoptosis in Cortical Neuronal Cultures by Iron Chelators Is Associated with Enhanced DNA Binding of Hypoxia-Inducible Factor-1 and ATF-1/CREB and Increased Expression of Glycolytic Enzymes, p21waf1/cip1, and Erythropoietin
1999 StandoutNobel
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1
1996 StandoutNobel
Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury
2000 Standout
Isolation and characterization of genomic and cDNA clones of human erythropoietin
1985 Nature
Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.
1999
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Erythropoietin receptor signalling is required for normal brain development
2002
Polycythemia in transgenic mice expressing the human erythropoietin gene.
1989 StandoutNobel
Correction of the Anemia of End-Stage Renal Disease with Recombinant Human Erythropoietin
1987 Standout
Works of M. Ueda being referenced
Enhancement of Activity of Lipase-Displaying Yeast Cells and Their Application to Optical Resolution of (R,S)-1-Benzyloxy-3-Chloro-2-Propyl Monosuccinate
2006
Position-independent and high-level expression of human α-lactalbumin in the milk of transgenic rats carrying a 210-kb YAC DNA
1997
Germ line and somatic mutations of BRAF V599E in ovarian carcinoma
2007
Hepatocyte Growth Factor and Its Variant with a Deletion of Five Amino Acids Are Distinguishable in Their Biological Activity and Tertiary Structure
1994
Human Hypoxic Signal Transduction through a Signature Motif in Hepatocyte Nuclear Factor 4
2002
K-ras gene mutations in early colorectal cancer ... flat elevated vs polyp-forming cancer....
1995
Effects of site-directed removal of N-glycosylation sites in human erythropoietin on its production and biological properties.
1991
Characterization and use of monoclonal antibodies directed against human erythropoietin that recognize different antigenic determinants
1989
Isolation of human erythropoietin with monoclonal antibodies.
1984
A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes.
1994
Characterization and use of monoclonal antibodies directed against human erythropoietin that recognize different antigenic determinants
1989
Hybridomas for production of monoclonal antibodies to human erythropoietin
1984