Citation Impact
Citing Papers
Sensitization of Human Carcinoma Cells to Alkylating Agents by Small Interfering RNA Suppression of 3-Alkyladenine-DNA Glycosylase
2005 StandoutNobel
Genome sequence of an industrial microorganism Streptomyces avermitilis : Deducing the ability of producing secondary metabolites
2001 StandoutNobel
Circadian oscillation of nucleotide excision repair in mammalian brain
2009 StandoutNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
2015 StandoutNobel
Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases
2004 StandoutNobel
MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
2007
A view on drug resistance in cancer
2019 StandoutNature
Bioactivation and Resistance to Mitomycin C
2004
Molecular Basis of Mitomycin C Resistance in Streptomyces
2002
The role of porphyrin chemistry in tumor imaging and photodynamic therapy
2010 Standout
Enzyme-Catalyzed Activation of Anticancer Prodrugs
2004
Head and neck cancer
2008 Standout
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
The role of p53 in base excision repair following genotoxic stress
2003
Synthesis of natural products containing the pyrrolic ring
2010
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells
1996 Standout
Scleroderma
2009 Standout
Involvement of Brca2 in DNA Repair
1998 StandoutNobel
The mitomycin bioreductive antitumor agents: Cross-linking and alkylation of DNA as the molecular basis of their activity
1997
Total Synthesis of (±)‐FR66979
2002
RecA-dependent incision of psoralen-crosslinked DNA by (A)BC excinuclease
1991 StandoutNobel
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
2003 StandoutNobel
Formation of adriamycin-DNA adductsin vitro
1994
Left-handed DNA: from Synthetic Polymers to Chromosomes
1983
The role of human alkyladenine glycosylase in cellular resistance to the chloroethylnitrosoureas
2003
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Cardiotoxicity of Chemotherapeutic Agents
2000
DNA Repair: Enzymatic Mechanisms and Relevance to Drug Response
1996
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Reductive activation of mitomycin C
1988
Structural studies of atom-specific anticancer drugs acting on DNA
1999
New insights on how nucleotide excision repair could remove DNA adducts induced by chemotherapeutic agents and psoralens plus UV-A (PUVA) in Escherichia coli cells
2003
Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents
1995 Nature
3-methyladenine DNA glycosylases: structure, function, and biological importance
1999
Repair of DNA interstrand cross-links
2001
Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation
2011 Standout
Pharmaceutically active secondary metabolites of microorganisms
1999
DNA Repair Excision Nuclease Attacks Undamaged DNA
2001 StandoutNobel
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Repairing DNA-methylation damage
2004
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations
2004 StandoutNobel
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Combining Asymmetric Catalysis with Natural Product Functionalization through Enantioselective α-Fluorination
2009
Functional Nucleic Acid Sensors
2009 Standout
Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice
1997 StandoutScience
Chemistry of Polyvalent Iodine
2008 Standout
Mitomycin Resistance in Streptomyces lavendulae Includes a Novel Drug-Binding-Protein-Dependent Export System
1999
UvrABC incision of N-methylmitomycin A-DNA monoadducts and cross-links
1989
Metal Complexes as Photo- and Radiosensitizers
1999
Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin
2005 Standout
Zn2+-Dependent Deoxyribozymes That Form Natural and Unnatural RNA Linkages
2005
Cyclometalated Phosphine-Based Pincer Complexes: Mechanistic Insight in Catalysis, Coordination, and Bond Activation
2003 Standout
Repeated observation of breast tumor subtypes in independent gene expression data sets
2003 Standout
1995 Merck Frosst Award Lecture Quinone methides: relevant intermediates in organic chemistry
1996
Isolation and Structure of a Covalent Cross-Link Adduct Between Mitomycin C and DNA
1987 Science
Oxidative Nucleobase Modifications Leading to Strand Scission
1998 Standout
Synthesis of 7-Epi (+)-FR900482: An Epimer of Comparable Anti-Cancer Activity
2008
3-Methyladenine DNA glycosylase-deficient Aag null mice display unexpected bone marrow alkylation resistance.
2002
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics
2002 Standout
Block Copolymer Lithography: Periodic Arrays of ~10 11 Holes in 1 Square Centimeter
1997 StandoutScience
Formation and Repair of Interstrand Cross-Links in DNA
2005
General Synthesis, First Crystal Structure, and Reactivity of Stable o-Quinone Methide Complexes of Cp*Ir
1998
Hyperfractionated Accelerated Chemoradiation With Concurrent Fluorouracil-Mitomycin Is More Effective Than Dose-Escalated Hyperfractionated Accelerated Radiation Therapy Alone in Locally Advanced Head and Neck Cancer: Final Results of the Radiotherapy Cooperative Clinical Trials Group of the German Cancer Society 95-06 Prospective Randomized Trial
2005
The role of reductive enzymes in cancer cell resistance to mitomycin C
2000
On The Latest Three‐Stage Development of Nanomedicines based on Upconversion Nanoparticles
2016
Characterization of a quinone reductase activity for the mitomycin C binding protein (MRD): Functional switching from a drug-activating enzyme to a drug-binding protein
2001
Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae
1997
Total Synthesis of (±)‐FR66979
2002
Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells.
1987
Chemistry of Biologically Important Synthetic Organoselenium Compounds
2001 Standout
Nucleotide Excision Repair- and Polymerase η-Mediated Error-Prone Removal of Mitomycin C Interstrand Cross-Links
2003
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Role of the C-10 Substituent in Mitomycin C-1−DNA Bonding
1996
DNA Interstrand Cross-Link Formation Induced by Bioxalomycin α2
1998
Stable o-Quinone Methide Complexes of Iridium: Synthesis, Structure, and Reversed Reactivity Imparted by Metal Complexation
2000
DNA Cross-Linking Agents as Antitumor Drugs
1998
Catalytic Asymmetric Intramolecular [4+2] Cycloaddition of In Situ Generated ortho‐Quinone Methides
2017 StandoutNobel
Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA
1999
Design of an intelligent sub-50 nm nuclear-targeting nanotheranostic system for imaging guided intranuclear radiosensitization
2014
Early Detection of Anthracycline Cardiotoxicity and Improvement With Heart Failure Therapy
2015 Standout
Taming Reactive Phenol Tautomers and o-Quinone Methides with Transition Metals: A Structure−Reactivity Relationship
2002
c-Abl Regulates p53 Levels under Normal and Stress Conditions by Preventing Its Nuclear Export and Ubiquitination
2001 StandoutNobel
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Conformational Flexibility of Phosphate, Phosphonate, and Phosphorothioate Methyl Esters in Aqueous Solution
1998 StandoutNobel
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Exposure to anticancer drugs can result in transgenerational genomic instability in mice
2012
TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer.
2003
Quinone Methide Alkylation of Deoxycytidine
1997
Works of M Tomasz being referenced
Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol 4 4Abbreviations: MC, mitomycin C; DIC, dicumarol; 2,7-DAM, 2,7-diaminomitosene; and XDH, xanthine dehydrogenase.
2001
Mechanism of monofunctional and bifunctional alkylation of DNA by mitomycin C
1988
Reductive alkylation of DNA by mitomycin A, a mitomycin with high redox potential
1991
Mitomycin C: small, fast and deadly (but very selective)
1995
Binding of 2,7-Diaminomitosene to DNA: Model for the Recognition of DNA by activated mitomycin C
1995
Isolation and structure of an intrastrand cross-link adduct of mitomycin C and DNA
1992
NMR and computational characterization of mitomycin cross-linked to adjacent deoxyguanosines in the minor groove of the d(T-A-C-G-T-A).cntdot.d(T-A-C-G-T-A) duplex
1990
Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity
1999
Conjugation of Glutathione and Other Thiols with Bioreductively Activated Mitomycin C. Effect of Thiols on the Reductive Activation Rate
1994
Effects of Glutathione on Alkylation and Crosslinking of DNA by Mitomycin C. Isolation of a Ternary Glutathione-Mitomycin-DNA Adduct
1994
Discussion
1998
Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C.
1998
DNA adducts of the mitomycins.
1994
Mitomycin C: a prototype bioreductive agent.
1994
Reaction of DNA with chemically or enzymatically activated mitomycin C: isolation and structure of the major covalent adduct.
1986
Mammalian 3-methyladenine DNA glycosylase protects against the toxicity and clastogenicity of certain chemotherapeutic DNA cross-linking agents.
1998
ChemInform Abstract: 2,7‐Diaminomitosene (I), a Monofunctional Mitomycin C Derivative, Alkylates DNA in the Major Groove. Structure and Base‐Sequence Specificity of the DNA Adduct and Mechanism of the Alkylation.
1997
Lack of Z-DNA conformation in mitomycin-modified polynucleotides having inverted circular dichroism.
1983
Antisense sequence-directed cross-linking of RNA oligonucleotides by mitomycin.
1997