Citation Impact
Citing Papers
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
1995 StandoutNatureNobel
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
SNAP receptors implicated in vesicle targeting and fusion
1993 StandoutNatureNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast
1989 StandoutNatureNobel
Unoccupied β-adrenoceptor-induced adenylyl cyclase stimulation in turkey erythrocyte membranes
1994
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 StandoutNatureNobel
Expression and purification of truncated, non-glycosylated turkey beta-adrenergic receptors for crystallization
2003
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin
1991 StandoutNatureNobel
Noradrenaline binding and the search for catecholamine receptors
1974 Nature
Coated pits, coated vesicles, and receptor-mediated endocytosis
1979 StandoutNatureNobel
Identification of adenylate cyclase-coupled beta-adrenergic receptors in frog erythrocytes with (minus)-[3-H] alprenolol.
1975 StandoutNobel
Influence of cholera toxin on the regulation of adenylate cyclase by GTP
1977
Role of endothelium in responses of vascular smooth muscle.
1983 StandoutNobel
?-Adrenergic receptors of frog erythrocytes
1979
Mode of coupling between hormone receptors and adenylate cyclase elucidated by modulation of membrane fluidity
1978 Nature
Independent Stimulation of Secretion and Protein Synthesis in Rat Parotid Gland
1969
Order of events in the yeast secretory pathway
1981 StandoutNobel
Adenyl Cyclase of Rat Parotid Gland
1970
Coupling of opiate receptors to adenylate cyclase: requirement for Na+ and GTP.
1979
Molecular Mechanisms of Coupling in Hormone Receptor‐Adenylate Cyclase Systems
1982 StandoutNobel
Altered guanine nucleotide hydrolysis as basis for increased adenylate cyclase activity after cholera toxin treatment.
1977
Message Transmission: Receptor Controlled Adenylate Cyclase System
1984 Science
Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.
1981 Standout
Resolution, reconstitution and kinetics of the primary action of a hormone receptor
1980 Nature
Mode of coupling between the β-adrenergic receptor and adenylate cyclase in turkey erythrocytes
1978
Isolated Hormone Receptors
1973 StandoutNobel
Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site
1977
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Regulation of beta-adrenergic receptors by guanyl-5'-yl imidodiphosphate and other purine nucleotides.
1976 StandoutNobel
Enhanced Myocardial Function in Transgenic Mice Overexpressing the β 2 -Adrenergic Receptor
1994 StandoutScienceNobel
Guanosine 5′, α-β-methylene, triphosphate, a novel GTP analog, causes persistent activation of adenylate cyclase: Evidence against pyrophosphorylation mechanism
1977
Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure
1989 StandoutScienceNobel
The role of hormone receptors and GTP-regulatory proteins in membrane transduction
1980 StandoutNatureNobel
RADIOAUTOGRAPHIC ANALYSIS OF THE SECRETORY PROCESS IN THE PAROTID ACINAR CELL OF THE RABBIT
1972 StandoutNobel
Reversible activation of hepatic adenylate cyclase by guanyl-5'-yl-(alpha,beta-methylene)diphosphonate and guanyl-5'-yl imidodiphosphate.
1977 StandoutNobel
G Proteins and Regulation of Adenylyl Cyclase
1989 StandoutNobel
Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analogues.
1988
Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.
1978
DYNAMIC CHANGES IN THE ULTRASTRUCTURE OF THE ACINAR CELL OF THE RAT PAROTID GLAND DURING THE SECRETORY CYCLE
1969
Correlation of beta-adrenergic receptor-stimulated [3H]GDP release and adenylate cyclase activation. Differences between frog and turkey erythrocyte membranes.
1981 StandoutNobel
Selective identification of ‘true’ β‐adrenergic receptors in the plasma membranes of rat adipocytes
1975
Enzyme secretion in mouse pancreas mediated by adenosine-3'5'-cyclic phosphate and inhibited by adenosine-3'-phosphate.
1968
A β-Adrenergic Receptor of the Turkey Erythrocyte
1973
The ß-adrenergic receptor and adenylate cyclase
1976 StandoutNobel
Specific Binding of β-Adrenergic Catecholamines to a Subcellular Fraction from Cardiac Muscle
1973 StandoutNobel
Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system.
1983 StandoutNobel
Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase
1983 StandoutNatureNobel
Activation of Turkey erythrocyte adenylate cyclase and blocking of the catecholamine-stimulated GTPase by guanosine 5′-(γ-thio) triphosphate
1977
Effects of colchicine on cyclic AMP levels in human leukocytes
1977
7‐O‐hemisuccinyl‐deacetyl forskolin—sepharose: a novel affinity support for purification of adenylate cyclase
1982
Reconstitution of catecholamine-stimulated guanosine triphosphatase activity
1983
Isolation of adenylate cyclase-free, beta-adrenergic receptor from turkey erythrocyte membranes by affinity chromatography.
1977
GTP-binding proteins in membranes and the control of adenylate cyclase activity.
1977
Hydrodynamic properties of the beta-adrenergic receptor and adenylate cyclase from wild type and varient S49 lymphoma cells.
1977 StandoutNobel
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes
1976
Functional alteration of the beta-adrenergic receptor during desensitization of mammalian adenylate cyclase by beta-agonists.
1984
Functional integrity of desensitized beta-adrenergic receptors.
1983 StandoutNobel
A G Protein Directly Regulates Mammalian Cardiac Calcium Channels
1987 Science
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
β-Adrenergic Receptor: Stereospecific Interaction of Iodinated β-Blocking Agent with High Affinity Site
1974 Science
Irreversible stimulation of adenylate cyclase activity of fat cell membranes by phosphoramidate and phosphonate analogs of GTP
1975
The effect of insulin and guanosine nucleotides on protein phosphorylations by sarcolemma membranes from skeletal muscle
1979
Hormonal regulation of peptide receptors and target cell responses
1979 Nature
Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes.
1977 StandoutNobel
Intracellular Aspects of the Process of Protein Synthesis
1975 StandoutScienceNobel
Identification of cardiac beta-adrenergic receptors by (minus) [3H]alprenolol binding.
1975 StandoutNobel
Coupling of glucagon receptor to adenylyl cyclase. Requirement of a receptor-related guanyl nucleotide binding site for coupling of receptor to the enzyme.
1979
Energy Production in Rat Parotid Gland
1970
Secretion granules of the rabbit parotid gland. Isolation, subfractionation, and characterization of the membrane and content subfractions.
1975 Nobel
The effect of calcium on amylase secretion by rat parotid slices
1970
Binding of [3H]guanylylimidodiphosphate to membranes: Lack of correlation with adenylate cyclase activation
1976
A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans
1987 StandoutNatureNobel
Irreversible activation of adenylate cyclase of toad erythrocyte plasma membrane by 5′-guanylylimidodiphosphate
1976
Receptor stability and channel conversion in the subsynaptic membrane of the developing mammalian neuromuscular junction
1980
Peptide hormone binding to receptors: A review of direct studies in vitro
1973
Activation of adenylate cyclase in hepatic membranes involves interactions of the catalytic unit with multimeric complexes of regulatory proteins.
1979 StandoutNobel
Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.
1979
Amylase secretion in rat parotid slices by apparent activation of endogenous catecholamine
1968
Evidence for distinct guanine nucleotide sites in the regulation of the glucagon receptor and of adenylate cyclase activity.
1977 StandoutNobel
ATP dependent calcium uptake by microsomal preparations from rat parotid and submaxillary glands
1970
Homologous desensitization of beta-adrenergic receptor coupled adenylate cyclase. Resensitization by polyethylene glycol treatment.
1985 StandoutNobel
β-Adrenoreceptors determine affinity but not intrinsic activity of adenylate cyclase stimulants
1979 StandoutNatureNobel
Control of Glycolysis in the Human Red Blood Cell
1966 StandoutNobel
Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model
1985 StandoutNatureNobel
Relationship between the beta-adrenergic receptor and adenylate cyclase.
1977 StandoutNobel
Two soluble forms of guanosine 5'-(beta,gamma-imino)triphosphate and fluoride-activated adenylate cyclase.
1976
Direct Activation of Mammalian Atrial Muscarinic Potassium Channels by GTP Regulatory Protein G k
1987 Science
The Binding Characteristics and Number of β-Adrenergic Receptors on the Turkey Erythrocyte
1974
Evidence for Interdependent Action of Glucagon and Nucleotides on the Hepatic Adenylate Cyclase System
1974 StandoutNobel
A β-Adrenergic Receptor of the Turkey Erythrocyte
1973
Beta-Adrenergic receptor interactions. Direct comparison of receptor interaction and biological activity.
1976
On the mechanism of activation of fat cell adenylate cyclase by guanine nucleotides. An explanation for the biphasic inhibitory and stimulatory effects of the nucleotides and the role of hormones.
1975 StandoutNobel
CONDENSING VACUOLE CONVERSION AND ZYMOGEN GRANULE DISCHARGE IN PANCREATIC EXOCRINE CELLS: METABOLIC STUDIES
1971 StandoutNobel
The characteristics of lubrol-solubilized adenylate cyclase from rat liver plasma membranes
1978 StandoutNobel
Slowly reversible binding of catecholamine to a nucleotide-sensitive state of the beta-adrenergic receptor.
1977 StandoutNobel
Calcium and the Exportable Protein in Rat Parotid Gland
1971
Parallel modulation of catecholamine activation of adenylate cyclase and formation of the high-affinity agonist.cntdot.receptor complex in turkey erythrocyte membranes by temperature and cis-vaccenic acid
1980 StandoutNobel
Involvement of vesicle coat material in casein secretion and surface regeneration.
1976
Catecholamine binding to the beta-adrenergic receptor.
1977 StandoutNobel
Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system
1978
Solubilization and characterization of the beta-adrenergic receptor binding sites of frog erythrocytes.
1976 StandoutNobel
Molecular distinction between fetal and adult forms of muscle acetylcholine receptor
1986 StandoutNatureNobel
Guanine nucleotide‐controlled interactions between components of adenylate cyclase
1979
Functional implantation of a solubilized β-adrenergic receptor in the membrane of a cell
1980
Transfer of glucagon receptor from liver membranes to a foreign adenylate cyclase by a membrane fusion procedure
1979
Identification of the Cardiac Beta-Adrenergic Receptor Protein: Solubilization and Purification by Affinity Chromatography
1972 StandoutNobel
Beta-Adrenergic receptor interactions. Characterization of iodohydroxybenzylpindolol as a specific ligand.
1976
Works of M. Schramm being referenced
Blocking of catecholamine activation of adenylate cyclase by N, N'dicyclohexyl carbodiimide in turkey erythrocytes.
1976
Secretion of Enzymes and Other Macromolecules
1967
The beta-adrenergic receptor survives solubilization in deoxycholate while forming a stable association with the agonist.
1984
Non-parallel transport of membrane proteins and content proteins during assembly of the secretory granule in rat parotid gland
1975
Epinephrine-Induced Vacuole Formation in Parotid Gland Cells and Its Independence of the Secretory Process
1971
Epinephrine Binding to the Catecholamine Receptor and Activation of the Adenylate Cyclase in Erythrocyte Membranes
1972
Hybridization of adenylate cyclase components by membrane fusion and the effect of selective digestion by trypsin.
1980
Probing of the coupling site of the beta-adrenergic receptor. Competition between different forms of the guanyl nucleotide binding protein for interaction with the receptor.
1982
Purification of secretory granules on a urografin gradient
1973
The catecholamine-responsive adenylate cyclase system and its modification by 5'guanylylimidodiphosphate.
1975
The Mechanism of Enzyme Secretion by the Cell
1967
Intracellular cyclic AMP production enhanced by a hormone receptor transferred from a different cell. beta-adrenergic responses in cultured cells conferred by fusion with turkey erythrocytes
1978
Trapping of the beta-adrenergic receptor in the hormone-induced state.
1983
A persistent active state of the adenylate cyclase system produced by the combined actions of isoproterenol and guanylyl imidodiphosphate in frog erythrocyte membranes.
1975 StandoutNobel
Coupling of hormone receptors to adenylate cyclase of different cells by cell fusion
1977 Nature
Delipidation of a beta-adrenergic receptor preparation and reconstitution by specific lipids.
1983
Transfer of the hormone receptor for vaso‐intestinal peptide to an adenylate cyclase system in another cell
1979
Locking of hormone in the beta-adrenergic receptor by attack on a sulfhydryl in an associated component.
1982
Coupling of catecholamine receptor from one cell with adenylate cyclase from another cell by cell fusion.
1976
Fatty acids as modulators of membrane functions: catecholamine-activated adenylate cyclase of the turkey erythrocyte.
1975
Tetrose Diphosphate, a Specific Inhibitor of Glyceraldehyde 3-Phosphate Dehydrogenase
1959