Citation Impact
Citing Papers
Cell-free cloning using φ29 DNA polymerase
2005 Nobel
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing
2012 Standout
Pyridoxal 5′-Phosphate Inhibition of Adenovirus DNA Polymerase
1996
Whole genome amplification and its impact on CGH array profiles
2008
Human Mismatch Repair
2005 StandoutNobel
The bacteriophage phi 29 DNA polymerase, a proofreading enzyme.
1992
3‘–>5‘ exonuclease active site of phi 29 DNA polymerase. Evidence favoring a metal ion-assisted reaction mechanism.
1994
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
The ϕ29 DNA polymerase:protein‐primer structure suggests a model for the initiation to elongation transition
2006 StandoutNobel
Analysis of replicative intermediates produced during bacteriophage φ29 DNA replication in vitro
1991
The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains
1997
Whole Genome Amplification for Array Comparative Genomic Hybridization Using DNA Extracted from Formalin-Fixed, Paraffin-Embedded Histological Sections
2009
DnaB from Thermus aquaticus Unwinds Forked Duplex DNA with an Asymmetric Tail Length Dependence
1999 StandoutNobel
Primer Terminus Stabilization at the φ29 DNA Polymerase Active Site
1995
Relating Structure to Function in 29 DNA Polymerase
1996
Genome coverage and sequence fidelity of 29 polymerase-based multiple strand displacement whole genome amplification
2004
An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminal protein
2000
DNA polymerase of the T4-related bacteriophages
2000
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Zinc and immune function: the biological basis of altered resistance to infection
1998
The Role of 3′-5′ Exonucleolytic Proofreading and Mismatch Repair in Yeast Mitochondrial DNA Error Avoidance
1998
A Conserved Insertion in Protein-primed DNA Polymerases is Involved in Primer Terminus Stabilisation
2003
Gel Shift and UV Cross-linking Analysis of Tetrahymena Telomerase
1995 StandoutNobel
Effects of internal deletions on the priming activity of the phage φ29 terminal protein
1989
Premature ageing in mice expressing defective mitochondrial DNA polymerase
2004 StandoutNature
[5] Purification of bacteriophage φ29 DNA polymerase
1995
Mutational analysis of ø29 DNA polymerase residues acting as ssDNA ligands for 3′-5′ exonucleolysis
1998
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
2001 StandoutNobel
Mutagenesis of a highly conserved lysine 340 of the PRD1 DNA polymerase
1994
Mutation detection and single-molecule counting using isothermal rolling-circle amplification
1998
Building a Replisome from Interacting Pieces
1999 StandoutNobel
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
1999 StandoutNobel
[22] Mutational analysis of bacteriophage φ29 DNA polymerase
1995
A Novel Kinetic Analysis to Calculate Nucleotide Affinity of Proofreading DNA Polymerases:
1995
Phage ø29 DNA polymerase residues involved in the proper stabilisation of the primer-terminus at the 3′-5′ exonuclease active site
2000
Two Positively Charged Residues of φ29 DNA Polymerase, Conserved in Protein-primed DNA Polymerases, are Involved in Stabilisation of the Incoming Nucleotide
2003
Site-directed mutagenesis of the YCDTDS amino acid motif of the Φ29 DNA polymerase
1990
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
Dissociation of the Protein Primer and DNA Polymerase after Initiation of Adenovirus DNA Replication
1997
An invariant lysine residue is involved in catalysis at the 3′-5′ exonuclease active site of eukaryotic-type DNA polymerases
1997
Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair
2002 StandoutNobel
Tapping diversity lost in transformations—in vitro amplification of ligation reactions
2006 StandoutNobel
Rapid Amplification of Plasmid and Phage DNA Using Phi29 DNA Polymerase and Multiply-Primed Rolling Circle Amplification
2001
DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro
1997 StandoutNobel
Impact of whole genome amplification on analysis of copy number variants
2008
Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B‐family polymerases
2007 StandoutNobel
Maternal and child undernutrition: global and regional exposures and health consequences
2008 Standout
The complete nucleotide sequence of the left very early region of Escherichia coli bacteriophage PRD1 coding for the terminal protein and the DNA polymerase
1987
Sequence Requirements for Protein-primed Initiation and Elongation of Phage Ø29 DNA Replication
2000
Role of the first aspartate residue of the “YxDTDS” motif of ø29 DNA polymerase as a metal ligand during both TP-primed and DNA-primed DNA synthesis
1998
Primary structure of the catalytic subunit of calf thymus DNA polymerase .delta.: sequence similarities with other DNA polymerases
1991
ø29 DNA polymerase residue Lys383, invariant at motif B of DNA-dependent polymerases, is involved in dNTP binding 1 1Edited by A. R. Fesht
1997
Structure of Taq polymerase with DNA at the polymerase active site
1996 StandoutNatureNobel
Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage φ29
2004 StandoutNobel
Viral Polymerases
2011
Identification of the Acidic Residues in the Active Site of DNA Polymerase III
1999
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Mechanisms of Initiation of Linear DNA Replication in Prokaryotes
1999
A conserved 3′→5′ exonuclease active site in prokaryotic and eukaryotic DNA polymerases
1989
Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain
2012
The crystal structure of the Thermus aquaticus DnaB helicase monomer
2007 StandoutNobel
Checkpoint-Dependent Activation of Mutagenic Repair in Saccharomyces cerevisiae pol3-01 Mutants
2000
Deoxynucleoside Triphosphate and Pyrophosphate Binding Sites in the Catalytically Competent Ternary Complex for the Polymerase Reaction Catalyzed by DNA Polymerase I (Klenow Fragment)
1995
Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
2002 StandoutNobel
Organization and evolution of bacterial and bacteriophage primase-helicase systems
1992
A computational approach for predicting off-target toxicity of antiviral ribonucleoside analogues to mitochondrial RNA polymerase
2018 StandoutNobel
The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase
2004 StandoutNobel
DNA Repair Excision Nuclease Attacks Undamaged DNA
2001 StandoutNobel
Function of the C-terminus of 29 DNA polymerase in DNA and terminal protein binding
2004
A positively charged residue of phi29 DNA polymerase, highly conserved in DNA polymerases from families A and B, is involved in binding the incoming nucleotide
2002
Tumour evolution inferred by single-cell sequencing
2011 StandoutNature
DNA Polymerases: Structural Diversity and Common Mechanisms
1999 StandoutNobel
A general structure for DNA-dependent DNA polymerases
1991
Protein-primed DNA replication: a transition between two modes of priming by a unique DNA polymerase
1997
Compilation and alignment of DNA polymerase sequences
1991
Aspartic acid residues at positions 190 and 192 of rat DNA polymerase .beta. are involved in primer binding
1991
The Drosophila RBP-J kappa gene encodes the binding protein for the immunoglobulin J kappa recombination signal sequence.
1991 StandoutNobel
Kinetic Analysis of an Efficient DNA-Dependent TNA Polymerase
2005 StandoutNobel
The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation
2008 StandoutScienceNobel
Exploring whole genome amplification as a DNA recovery tool for molecular genetic studies.
2005
Isolation, characterization, and kinetic properties of truncated forms of T4 DNA polymerase that exhibit 3‘-5‘ exonuclease activity.
1994
A specific subdomain in φ29 DNA polymerase confers both processivity and strand-displacement capacity
2005 StandoutNobel
Phi 29 DNA polymerase active site. Mutants in conserved residues Tyr254 and Tyr390 are affected in dNTP binding.
1992
Two Neurospora mitochondrial plasmids encode DNA polymerases containing motifs characteristic of family B DNA polymerases but lack the sequence Asp-Thr-Asp.
1993
Domains of Escherichia coli primase: functional activity of a 47-kDa N-terminal proteolytic fragment.
1994 StandoutNobel
Polymerase structures and function: variations on a theme?
1995 StandoutNobel
Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli.
1990 StandoutNobel
Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
1992 StandoutScience
DNA Polymerase-Mediated DNA Synthesis on a TNA Template
2002 StandoutNobel
Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity.
1991
Suicide recombination substrates yield covalent lambda integrase-DNA complexes and lead to identification of the active site tyrosine.
1988
φ29 DNA Polymerase–Terminal Protein Interaction. Involvement of Residues Specifically Conserved Among Protein-primed DNA Polymerases
2004
Localization of the active site of the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme
1997
Highly Efficient DNA Synthesis by the Phage ϕ 29 DNA Polymerase
1989
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair
2001 StandoutNobel
Primary structure of bacteriophage M2 DNA polymerase: conserved segments within protein-priming DNA polymerases and DNA polymerase I of Escherichia coli
1989
TempliPhi: A sequencing template preparation procedure that eliminates overnight cultures and DNA purification.
2003
Determinants of nucleotide sugar recognition in an archaeon DNA polymerase
1999
An in Vitro Selection System for TNA
2005 StandoutNobel
Membrane Fusion and Exocytosis
1999 StandoutNobel
Point mutations which drastically affect the polymerization activity of encephalomyocarditis virus RNA-dependent RNA polymerase correspond to the active site of Escherichia coli DNA polymerase I.
1992
Cloning and template activity of the origins of replication of phage φ29 DNA
1986
Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA
1993 StandoutScienceNobel
Schizosaccharomyces pombe cdc 20 + encodes DNA polymerase ɛ and is required for chromosomal replication but not for the S phase checkpoint
1997 StandoutNobel
DNA Replication Fidelity
2000
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
2007 StandoutNobel
The Multiple Biological Roles of the 3′→5′ Exonuclease ofSaccharomyces cerevisiaeDNA Polymerase δ Require Switching between the Polymerase and Exonuclease Domains
2004
Crystal Structures of an NH2-Terminal Fragment of T4 DNA Polymerase and Its Complexes with Single-Stranded DNA and with Divalent Metal Ions
1996 StandoutNobel
Primer-terminus stabilization at the 3′-5′ exonuclease active site of phi29 DNA polymerase. Involvement of two amino acid residues highly conserved in proofreading DNA polymerases.
1996
Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli.
1992
TempliPhi, φ29 DNA Polymerase Based Rolling Circle Amplification of Templates for DNA Sequencing
2002
Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR.
1994
Bacteriophage PRD1 DNA polymerase: evolution of DNA polymerases.
1987
Replication of phage phi 29 DNA with purified terminal protein and DNA polymerase: synthesis of full-length phi 29 DNA.
1985
Conformational Flexibility of Phosphate, Phosphonate, and Phosphorothioate Methyl Esters in Aqueous Solution
1998 StandoutNobel
Comprehensive human genome amplification using multiple displacement amplification
2002
TNA Synthesis by DNA Polymerases
2003 StandoutNobel
DNA Bending by Asymmetric Phosphate Neutralization
1994 Science
Effect of NH4+ ions on phi 29 DNA-protein p3 replication: formation of a complex between the terminal protein and the DNA polymerase
1987
Works of M. Salas being referenced
Characterization and purification of a phage phi 29-encoded DNA polymerase required for the initiation of replication.
1984
A DNA curvature can substitute phage phi 29 regulatory protein p4 when acting as a transcriptional repressor.
1991
The highly conserved amino acid sequence motif Tyr-Gly-Asp-Thr-Asp-Ser in alpha-like DNA polymerases is required by phage phi 29 DNA polymerase for protein-primed initiation and polymerization.
1990
Initiation of DNA Replication by Primer Proteins: Bacteriophage ø29 and Its Relatives
1988
Formation of a covalent complex between the terminal protein of pneumococcal bacteriophage Cp-1 and 5'-dAMP
1986
Phi 29 DNA polymerase active site. The conserved amino acid motif “Kx3NSxYG” is involved in template-primer binding and dNTP selection
1993
Induction of interferon-γ in human leukocyte cultures stimulated by Zn2+
1987
A DNA binding motif coordinating synthesis and degradation in proofreading DNA polymerases.
1996
Site-directed mutagenesis at the Exo III motif of phi 29 DNA polymerase; overlapping structural domains for the 3′-5′ exonuclease and strand-displacement activities.
1992
Interaction of the bacteriophage phi 29 protein p6 with double-stranded DNA.
1988
Structural and functional analysis of temperature-sensitive mutants of the phage phi 29 DNA polymerase.
1990
Fidelity of phi 29 DNA polymerase. Comparison between protein-primed initiation and DNA polymerization.
1993
Phi 29 DNA polymerase active site. Residue ASP249 of conserved amino acid motif “Dx2SLYP” is critical for synthetic activities.
1993
Initiation of phi 29 DNA replication occurs at the second 3' nucleotide of the linear template: a sliding-back mechanism for protein-primed DNA replication.
1992