Citation Impact
Citing Papers
Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabiLization of β-catenin–TCF interaction
2008
Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment
2010
Wnt/β-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency
2007
Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex
2002
Dimerization Choices Control the Ability of Axin and Dishevelled to Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase
2000
Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy
2016
G Protein-coupled Receptor Kinases Phosphorylate LRP6 in the Wnt Pathway
2009 StandoutNobel
Dynamic recruitment of axin by Dishevelled protein assemblies
2007
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
2001
A view on drug resistance in cancer
2019 StandoutNature
Regulation of Casein Kinase Iϵ Activity by Wnt Signaling
2004
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
2010 StandoutNature
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Oncogenic kinase signalling
2001 StandoutNature
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines
2023 StandoutNobel
Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism
2002 Standout
Integrating liquid biopsies into the management of cancer
2017
Apoptosis: controlled demolition at the cellular level
2007 Standout
GSK3, a master switch regulating cell-fate specification and tumorigenesis
2000
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
The many roles of PTK7: A versatile regulator of cell–cell communication
2012
β-Catenin destruction complex: insights and questions from a structural perspective
2006
Posttranslational Regulation of Drosophila PERIOD Protein by Protein Phosphatase 2A
2004
Optimised Pre-Analytical Methods Improve KRAS Mutation Detection in Circulating Tumour DNA (ctDNA) from Patients with Non-Small Cell Lung Cancer (NSCLC)
2016
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation
2006
Synergistic Activation of the Wnt Signaling Pathway by Dvl and Casein Kinase Iε
2001
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Restriction of intestinal stem cell expansion and the regenerative response by YAP
2012 Nature
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Regulation of TCF3 by Wnt-Dependent Phosphorylation during Vertebrate Axis Specification
2010
Vaccine Adjuvants: Putting Innate Immunity to Work
2010
Crystal structure of a β-catenin/Axin complex suggests a mechanism for the β-catenin destruction complex
2003
Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase
2010 StandoutNobel
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
Diabetic Retinopathy
2012 Standout
The Vertebrate Primary Cilium in Development, Homeostasis, and Disease
2009
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Wnt/β-Catenin Signaling and Disease
2012 Standout
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
2005 StandoutNobel
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
Emerging Biological Principles of Metastasis
2017 Standout
The many ways of Wnt in cancer
2007
WNT Signaling and Lymphocyte Development
2002
Gefitinib Treatment in EGFR Mutated Caucasian NSCLC: Circulating-Free Tumor DNA as a Surrogate for Determination of EGFR Status
2014
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Microtubules as a target for anticancer drugs
2004 Standout
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy
2017
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Missing Links in GSK3 Regulation
2001
Adipocyte differentiation from the inside out
2006 Standout
Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing
2001
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
Rapid, Wnt-Induced Changes in GSK3β Associations that Regulate β-Catenin Stabilization Are Mediated by Gα Proteins
2005
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Erk Associates with and Primes GSK-3β for Its Inactivation Resulting in Upregulation of β-Catenin
2005
Wnt signalling in stem cells and cancer
2005 StandoutNature
Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
2018 Standout
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization
2007
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
2007
VEGF Activation of Protein Kinase C Stimulates Occludin Phosphorylation and Contributes to Endothelial Permeability
2006
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Protein–protein interactions define specificity in signal transduction
2000
Oxidant stress and endothelial cell dysfunction
2001
Wnt Induces LRP6 Signalosomes and Promotes Dishevelled-Dependent LRP6 Phosphorylation
2007 Science
Identification of a Specific Inhibitor of the Dishevelled PDZ Domain
2005
Prospective Validation of Rapid Plasma Genotyping for the Detection ofEGFRandKRASMutations in Advanced Lung Cancer
2016
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors
2002
LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling:Arrows point the way
2004
Axin Facilitates Smad3 Activation in the Transforming Growth Factor β Signaling Pathway
2001
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Live-Cell Labeling of Specific Protein Glycoforms by Proximity-Enhanced Bioorthogonal Ligation
2015 StandoutNobel
THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE
2004 Standout
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity
2005
Inhibition of the Wnt Signaling Pathway by Idax, a Novel Dvl-Binding Protein
2001
A Small Conserved Domain of Drosophila PERIOD Is Important for Circadian Phosphorylation, Nuclear Localization, and Transcriptional Repressor Activity
2007 StandoutNobel
PP2A:B56ϵ is required for Wnt/β-catenin signaling during embryonic development
2003
Nascent-Seq analysis of Drosophila cycling gene expression
2013 StandoutNobel
The tumor vascular targeting agent combretastatin A–4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells
2002
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5
2006 StandoutNobel
Emerging molecular mechanisms of brain tumour oedema
2001
Inflammatory pain alters blood-brain barrier permeability and tight junctional protein expression
2001
CASK Participates in Alternative Tripartite Complexes in which Mint 1 Competes for Binding with Caskin 1, a Novel CASK-Binding Protein
2002 StandoutNobel
Works of M. Ratcliffe being referenced
Agreement between Programmed Cell Death Ligand-1 Diagnostic Assays across Multiple Protein Expression Cutoffs in Non–Small Cell Lung Cancer
2017
Protein phosphorylation and the regulation of cell-cell junctions in brain endothelial cells.
1997
ctDNA Determination of EGFR Mutation Status in European and Japanese Patients with Advanced NSCLC: The ASSESS Study
2016
Dephosphorylation of the Cadherin-associated p100/p120 Proteins in Response to Activation of Protein Kinase C in Epithelial Cells
1997
A Positive Role for the PP2A Catalytic Subunit in Wnt Signal Transduction
2000
Nuclear localization is required for Dishevelled function in Wnt/β-catenin signaling
2005
CpG-containing immunostimulatory DNA sequences elicit TNF-α–dependent toxicity in rodents but not in humans
2009
Panel Based MALDI-TOF Tumour Profiling Is a Sensitive Method for Detecting Mutations in Clinical Non Small Cell Lung Cancer Tumour
2014
Determining the Prevalence of EGFR Mutations in Asian and Russian Patients (PTS) with Advanced Non-Small-Cell Lung Cancer (ANSCLC) of Adenocarcinoma (ADC) and Non-Adc Histology: Ignite Study
2015
Abstract LB-094: A comparative study of PD-L1 diagnostic assays and the classification of patients as PD-L1 positive and PD-L1 negative
2016
Investigating the Utility of Circulating-Free Tumour-Derived Dna (CTDNA) in Plasma for the Detection of Epidermal Growth Factor Receptor (EGFR) Mutation Status in European and Japanese Patients (PTS) with Advanced Non-Small-Cell Lung Cancer (ANSCLC): Assess Study
2015
Guide to detecting epidermal growth factor receptor (EGFR) mutations in ctDNA of patients with advanced non-small-cell lung cancer
2016
Dephosphorylation of the catenins p120 and p100 in endothelial cells in response to inflammatory stimuli
1999
Interaction of Dishevelled and Xenopus Axin-Related Protein Is Required for Wnt Signal Transduction
2000