Citation Impact
Citing Papers
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
2009 StandoutNobel
Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer.
1999
Mismatch repair deficiency associated with overexpression of the MSH3 gene
1998
Mismatch repair, genetic stability and tumour avoidance
1995 StandoutNobel
Requirement of the Yeast MSH3 and MSH6 Genes for MSH2-dependent Genomic Stability
1996
An Olfactory Sensory Map in the Fly Brain
2000 StandoutNobel
Identification of mismatch repair genes and their role in the development of cancer
1995
Strand-specific Mismatch Repair in Mammalian Cells
1997 StandoutNobel
MutS homologs in mammalian cells
1997
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
The Escherichia coli MutS DNA mismatch binding protein specifically binds O6-methylguanine DNA lesions
1996
Identification of a Second MutL DNA Mismatch Repair Complex (hPMS1 and hMLH1) in Human Epithelial Cells
2000
Genetic instabilities in human cancers
1998 StandoutNature
hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
1996
Spontaneous mutagenesis: Experimental, genetic and other factors
1992
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
When Checkpoints Fail
1997 StandoutNobel
Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents
1992 StandoutNobel
A Spatial Map of Olfactory Receptor Expression in the Drosophila Antenna
1999 StandoutNobel
The Hallmarks of Cancer
2000 Standout
Lessons from Hereditary Colorectal Cancer
1996 Standout
DNA mismatch repair and mutation avoidance pathways
2002
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
Telomere Dysfunction Increases Mutation Rate and Genomic Instability
2001 StandoutNobel
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
p53 Protein Exhibits 3′-to-5′ Exonuclease Activity
1996
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
DNA mismatch repair proteins promote apoptosis and suppress tumorigenesis in response to UVB irradiation: an in vivo study
2004
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
MutS Preferentially Recognizes Cisplatin- over Oxaliplatin-modified DNA
2002
DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro
1997 StandoutNobel
Resistance to 6-thioguanine in mismatch repair-deficient human cancer cell lines correlates with an increase in induced mutations at the HPRT locus
1998
Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks
2010
Replication errors: cha(lle)nging the genome
1998
Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice
1999
Deoxyribonucleoside triphosphate levels: A critical factor in the maintenance of genetic stability
1994
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Genetic instability in colorectal cancers
1997 StandoutNature
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
Reduction to homozygosity is the predominant spontaneous mutational event in cultured human lymphoblastoid cells
1991
Two Large Families of Chemoreceptor Genes in the NematodesCaenorhabditis elegans and Caenorhabditis briggsae Reveal Extensive Gene Duplication, Diversification, Movement, and Intron Loss
1998
Molecular themes in oncogenesis
1991 StandoutNobel
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
1995
Two genetic hits (more or less) to cancer
2001
Reversal of methylation tolerance by transfer of human chromosome 2
1997
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
2001 StandoutNobel
Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα
1998 StandoutNobel
DNA methyltransferase Dnmt1 and mismatch repair
2004
Mismatch Repair Deficiency in Phenotypically Normal Human Cells
1995 StandoutScienceNobel
Hypermutagenic PCR Involving All Four Transitions and a Sizeable Proportion of Transversions
1996
DNA mismatch repair and cancer
2001
DNA Mismatch Repair-dependent Response to Fluoropyrimidine-generated Damage
2004
Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: The role of dna base damage
1990
DNA mismatch repair: Molecular mechanism, cancer, and ageing
2008
DNA damage tolerance, mismatch repair and genome instability
1994
Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation
2003
Mechanisms of resistance to cisplatin
2001
Hypermutability and mismatch repair deficiency in RER+ tumor cells
1993 StandoutNobel
Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability
2000 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Mammalian DNA Mismatch Repair
1999
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
1981
Increased Rate of Base Substitution in a Hamster Mutator Strain Obtained during Serial Selection for Gene Amplification
1990
Excision-amplification of mitochondrial DNA during senescence in Podospora anserina
1987
Recombination-dependent deletion formation in mammalian cells deficient in the nucleotide excision repair gene ERCC1
1997
Loss of DNA mismatch repair in acquired resistance to cisplatin.
1996
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
1995 StandoutScienceNobel
Mutations of GTBP in Genetically Unstable Cells
1995 Science
Genetic instability and darwinian selection in tumours
1999
Quality Control by DNA Repair
1999 StandoutScienceNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in Yeast
1994 Science
Structural alterations of DNA ligase I in Bloom syndrome.
1987 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
A mutator phenotype characterizes one of two complementation groups in human cells tolerant to methylation damage.
1995
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair
2001 StandoutNobel
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
1996 StandoutNobel
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.
1996
Deletion of a splice donor site ablates expression of the following exon and produces an unphosphorylated RB protein unable to bind SV40 T antigen.
1990
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Reversibility of cyclization of the tetrahymena rRNA intervening sequence: implication for the mechanism of splice site choice
1985 StandoutNobel
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
Excision-amplification of mitochondrial DNA during senescence in Podospora anserina
1985
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.
1995 StandoutNobel
The human MLH1 cDNA complements DNA mismatch repair defects in Mlh1-deficient mouse embryonic fibroblasts.
1999
Increased Mutational Rates in Chinese Hamster Ovary Cells Serially Selected for Drug Resistance
1983
Molecular analysis of spontaneous hypoxanthine phosphoribosyltransferase mutations in thioguanine-resistant HL-60 human leukemia cells.
1989
Enzymatic Processing of Radiation-Induced Free Radical Damage in DNA
1998
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
Mechanisms underlying losses of heterozygosity in human colorectal cancers
2001
Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.
2001
Variable deletion and duplication at recombination junction ends: Implication for staggered double-strand cleavage in class-switch recombination
2001 StandoutNobel
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Functional Overlap in Mismatch Repair by Human MSH3 and MSH6
1998
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype
1996
Increased Hypermutation at G and C Nucleotides in Immunoglobulin Variable Genes from Mice Deficient in the MSH2 Mismatch Repair Protein
1998
A hPMS2 Mutant Cell Line Is Defective in Strand-specific Mismatch Repair
1995
Mismatch Repair, Genetic Stability, and Cancer
1994 StandoutScienceNobel
Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes
1996 Science
Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coli.
1996
Biochemistry and genetics of eukaryotic mismatch repair.
1996
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair
1997 StandoutNobel
Lack of the DNA repair protein O6-methylguanine-DNA methyltransferase in histologically normal brain adjacent to primary human brain tumors.
1996
Works of M Meuth being referenced
The structure of mutation in mammalian cells
1990
The Influence of a (GT)29 Microsatellite Sequence on Homologous Recombination in the Hamster Adenine Phosphoribosyltransferase Gene
1996
Molecular analysis of mutations in mutator colorectal carcinoma cell lines
1995
Molecular patterns of aprt gene rearrangements.
1990
Multiple dispersed spontaneous mutations: a novel pathway of mutation in a malignant human cell line.
1991
Mutator phenotypes in human colorectal carcinoma cell lines.
1994
Spontaneous deletion formation at the aprt locus of hamster cells: the presence of short sequence homologies and dyad symmetries at deletion termini.
1986
DNA sequence analysis of spontaneous mutations at the aprt locus of hamster cells.
1987
Mutator phenotype in Msh2-deficient murine embryonic fibroblasts.
1997
Next-nucleotide effects in mutations driven by DNA precursor pool imbalances at the aprt locus of Chinese hamster ovary cells.
1987
Expression of the endogenous O6-methylguanine-DNA-methyltransferase protects Chinese hamster ovary cells from spontaneous G:C to A:T transitions.
1992
Sensitivity of a mutator gene in Chinese hamster ovary cell to deoxynucleoside triphosphate pool alterations.
1981
Increased rate of base substitution in a hamster mutator strain obtained during serial selection for gene amplification.
1990
Structural alterations of the aprt locus induced by deoxyribonucleoside triphosphate pool imbalances in Chinese hamster ovary cells.
1984
Biochemical characterization of the hamster thy mutator gene and its revertants.
1984
Characterization of a mutator gene in Chinese hamster ovary cells.
1979
A novel pathway for transversion mutation induced by dCTP misincorporation in a mutator strain of CHO cells.
1989