Standout Papers
Citation Impact
Citing Papers
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis
1989 Nature
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
Ordering S phase and M phase in the cell cycle
1994 StandoutNobel
DNA methylation and chromatin structure
1991
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Extracellular vesicles for drug delivery
2016
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1998 StandoutNature
Human ubiquitin-activating enzyme (E1): Compensation for heat-labile mouse E1 and its gene localization on the X chromosome
1991
The Ubiquitin-activating Enzyme E1 Is Phosphorylated and Localized to the Nucleus in a Cell Cycle-dependent Manner
1996 StandoutNobel
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
The generation of diversity and pattern in animal development
1992 StandoutNobel
The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1
1992
Hhal methyltransferase flips its target base out of the DNA helix
1994 Nobel
Suppression of intestinal neoplasia by DNA hypomethylation
1995
Lactacystin and clasto-Lactacystin β-Lactone Modify Multiple Proteasome β-Subunits and Inhibit Intracellular Protein Degradation and Major Histocompatibility Complex Class I Antigen Presentation
1997
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
A role for the ubiquitin-dependent proteolytic pathway in MHC class l-restricted antigen presentation
1993 Nature
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Principles of CDK regulation
1995 StandoutNature
The measurement of ubiquitin and ubiquitinated proteins
1999
Structure of 20S proteasome from yeast at 2.4Å resolution
1997 StandoutNatureNobel
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Endocytosis and Degradation of the Growth Hormone Receptor Are Proteasome-dependent
2000
Degradation of the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) by the Ubiquitin-Proteasome Pathway
2000 StandoutNobel
Cyclin is degraded by the ubiquitin pathway
1991 StandoutNature
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1998 StandoutNature
Degradation of CFTR by the ubiquitin-proteasome pathway
1995 Standout
Exosomes: Therapy delivery tools and biomarkers of diseases
2017
Allelic inactivation regulates olfactory receptor gene expression
1994 StandoutNobel
Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor
1999
Cut2 proteolysis required for sister-chromatid separation in fission yeast
1996 StandoutNatureNobel
Independent inactivation of MPF and cytostatic factor (Mos) upon fertilization of Xenopus eggs
1991 StandoutNatureNobel
Generation and testing of clinical-grade exosomes for pancreatic cancer
2018
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex
1994 StandoutNobel
Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein–Barr virus nuclear antigen 1
1997 StandoutNobel
Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1.
1991 StandoutNobel
A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme.
1993
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Delineation of DNA replication time zones by fluorescence in situ hybridization.
1992
STATs and Gene Regulation
1997 StandoutScience
Routes and mechanisms of extracellular vesicle uptake
2014 Standout
Cancer Cell Cycles
1996 StandoutScience
Immunoelectron microscopic localization of the ubiquitin-activating enzyme E1 in HepG2 cells.
1992 StandoutNobel
Human ubiquitin-activating enzyme, E1. Indication of potential nuclear and cytoplasmic subpopulations using epitope-tagged cDNA constructs
1994 StandoutNobel
Plasticity of the Differentiated State
1985 Science
Isoforms of mammalian ubiquitin-activating enzyme.
1992
Complementation by a Cloned Human Ubiquitin-Activating Enzyme E1 of the S-Phase-Arrested Mouse FM3A Cell Mutant with Thermolabile E1.
1992
Site of catabolite inactivation
1994 StandoutNatureNobel
Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation.
1996
Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase
1997 StandoutNobel
E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins.
1996 StandoutNobel
The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle
2010
Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis
2002
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Crystal Structure of DNA Photolyase from Escherichia coli
1995 StandoutScienceNobel
Nuclear localization of the ubiquitin-activating enzyme, E1, is cell-cycle-dependent
1994 StandoutNobel
The ubiquitin-activating enzyme, E1, is required for stress-induced lysosomal degradation of cellular proteins
1991 StandoutNobel
UBIQUITIN AND THE CONTROL OF PROTEIN FATE IN THE SECRETORY AND ENDOCYTIC PATHWAYS
1998
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Degradation of the tumor suppressor protein p53 by the ubiquitin-mediated proteolytic system requires a novel species of ubiquitin-carrier protein, E2
1994 StandoutNobel
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway
1998 StandoutNobel
ANTIGEN PROCESSING AND PRESENTATION BY THE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX
1996
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Degradation of the Proto-Oncogene Product c-Fos by the Ubiquitin Proteolytic System In Vivo and In Vitro: Identification and Characterization of the Conjugating Enzymes
1995 StandoutNobel
Recalibrated linkage map of Escherichia coli K-12
1976
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Altered ubiquitination and stability of aquaporin-1 in hypertonic stress
2001 StandoutNobel
Unique insertion site of Tn7 in the E. coli chromosome
1982 StandoutNatureNobel
Ubiquitin-activating enzyme, E1, is associated with maturation of autophagic vacuoles.
1992 StandoutNobel
Rescue of the complex temperature-sensitive phenotype of Chinese hamster ovary E36ts20 cells by expression of the human ubiquitin-activating enzyme cDNA
1994 StandoutNobel
UBA 1: an essential yeast gene encoding ubiquitin-activating enzyme.
1991
The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.
1996 StandoutNobel
From intestine to muscle: Nuclear reprogramming through defective cloned embryos
2002 StandoutNobel
Cloning of ubiquitin activating enzyme from wheat and expression of a functional protein in Escherichia coli.
1990
Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase.
1995 StandoutNobel
Works of M. Marcus being referenced
Cloning of a human S-phase cell cycle gene: use of transient expression for screening.
1987
Regulation of mouse satellite DNA replication time.
1988
Mapping of the aspartase gene in Escherichia coli K-12.
1969
Partial purification and characterization of the mRNA complementing a temperature-sensitive S-phase cell cycle mutation.
1984
A Chinese hamster cell cycle mutant arrested at G2 phase has a temperature-sensitive ubiquitin-activating enzyme, E1.
1988 StandoutNobel
FedExosomes: Engineering Therapeutic Biological Nanoparticles that Truly Deliver
2013