Citation Impact
Citing Papers
The Bovine Calpastatin Gene Promoter and a New N-terminal Region of the Protein Are Targets for cAMP-dependent Protein Kinase Activity
1998
A circular dichroism study of preferential hydration and alcohol effects on a denatured protein, pig calpastatin domain I
1997
cAMP responsiveness of the bovine calpastatin gene promoter
1998
Crystal structure of calcium bound domain VI of calpain at 1.9 Å resolution and its role in enzyme assembly, regulation, and inhibitor binding
1997
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
Pathophysiological role of calpain in experimental demyelination
1999
Purification of μ-Calpain by a Novel Affinity Chromatography Approach. NEW INSIGHTS INTO THE MECHANISM OF THE INTERACTION OF THE PROTEASE WITH TARGETS
1995
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
2002 StandoutNatureNobel
Identification of a signal for rapid export of proteins from the nucleus
1995 StandoutNobel
Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB
1999 Standout
cDNA Cloning of Human Calpastatin: Sequence Homology Among Human, Pig, and Rabbit Calpastatins
1989
Drosophila Rhomboid-1 Defines a Family of Putative Intramembrane Serine Proteases
2001
Phosphorylation of p105 PEST Sequences via a Redox-insensitive Pathway Up-regulates Processing to p50 NF-κB
1996
Cells’ Perception of Position in a Concentration Gradient
1998 StandoutNobel
Bovine skeletal muscle calpastatin: cloning, sequence analysis, and steady-state mRNA expression
1994
Effects of Epinephrine Infusion on Expression of Calpastatin in Porcine Cardiac and Skeletal Muscle
2000
Immunoaffinity purification of calpastatin and calpastatin constructs
2002
The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters
1998 StandoutNobel
Domain structure of calpain: mapping the binding site for calpastatin
1994
Rat brain contains multiple mRNAs for calpastatin1
1998
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
Cleavage of Doublecortin-like Kinase by Calpain Releases an Active Kinase Fragment from a Microtubule Anchorage Domain
2001
Characterization of a functional domain of human calpastatin
1990
Microinjection of Calpastatin Inhibits Fusion in Myoblasts
1999
Multiple forms of rat calpastatin cDNA in the coding region of functionally unknown amino-terminal domain
1992
A New Subfamily of Vertebrate Calpains Lacking a Calmodulin-Like Domain: Implications for Calpain Regulation and Evolution
1997
Activation of NF-κB by Phosphatase Inhibitors Involves the Phosphorylation of IκBα at Phosphatase 2A-sensitive Sites
1995
A Distinct Nuclear Import Pathway Used by Ribosomal Proteins
1997 StandoutNobel
Ubiquitin-mediated Processing of NF-κB Transcriptional Activator Precursor p105
1995 StandoutNobel
The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors
1992 StandoutNobel
A Ca2+ Switch Aligns the Active Site of Calpain
2002
Poly(ADP-ribose) polymerase interacts with a novel human ubiquitin conjugating enzyme: hUbc9
1997
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
2002
Purification and Characterization of the Active-Site-Mutated Recombinant Human μ-Calpain Expressed in Baculovirus-Infected Insect Cells
1998
Mechanisms for Generating the Autonomous cAMP-Dependent Protein Kinase Required for Long-Term Facilitation in Aplysia
1999 StandoutNobel
Regulation of Cyclin D1 by Calpain Protease
1997
Temporal relationships between de novo protein synthesis, calpain and caspase 3-like protease activation, and DNA fragmentation during apoptosis in septo-hippocampal cultures
1998
An endogenous inhibitor of calcium‐activated neutral protease in UMX 7.1 hamster dystrophy
1991
Calpain inhibition: an overview of its therapeutic potential
1994
Cleavage of Focal Adhesion Kinase by Different Proteases during Src-regulated Transformation and Apoptosis
2001
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
A calpain-like activity insensitive to calpastatin in Drosophila melanogaster
2002
Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates
2000
Ikappa Balpha is a target for the mitogen-activated 90kDa ribosomal S6 kinase
1997
Proteasome inhibitors induce mitochondria‐independent apoptosis in human glioma cells
1999 StandoutNobel
Mapping of calpastatin and three microsatellites to porcine chromosome 2q2.1-q2.4
1998
Calpain and calpastatin regulate neutrophil apoptosis
1999
Preference of calcium‐dependent interactions between calmodulin‐like domains of calpain and calpastatin subdomains
1995
Interaction of Fas(Apo‐1/CD95) with proteins implicated in the ubiquitination pathway
1997
Calpastatin Expression in Porcine Cardiac and Skeletal Muscle and Partial Gene Structure
2001
The immune response of Drosophila
2003 StandoutNatureNobel
Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia
1997 StandoutNobel
Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.
1995 Standout
Inhibition of Calpain Blocks Platelet Secretion, Aggregation, and Spreading
1999
Expression of three calpain isoform genes in human skeletal muscles
1998
Both ALG-2 and Peflin, Penta-EF-hand (PEF) Proteins, Are Stabilized by Dimerization through Their Fifth EF-Hand Regions
2002
Calpains: Intact and active?
1997
p53-dependent Induction of Apoptosis by Proteasome Inhibitors
1997
Calpastatin Is Up-regulated in Response to Hypoxia and Is a Suicide Substrate to Calpain after Neonatal Cerebral Hypoxia-Ischemia
1999
Development and Therapeutic Potential of Calpain Inhibitors
1996
A light-entrainment mechanism for the Drosophila circadian clock
1996 StandoutNatureNobel
Tyrosine Phosphorylation of IκB-α Activates NF-κB without Proteolytic Degradation of IκB-α
1996
The Structure of Calcium-Free Human m-Calpain Implications for Calcium Activation and Function
2001
Intracellular Proteinases of Invertebrates: Calcium-Dependent and Proteasome/Ubiquitin-Dependent Systems
1998
An Improved Purification Protocol for Heart and Skeletal Muscle Calpastatin Reveals Two Isoforms Resulting from Alternative Splicing
1998
Generation, Control, and Processing of Cellular Calcium Signals
2001
Neuronal Cell Death
1998
Structure of Mouse Calpastatin Isoforms: Implications of Species-Common and Species-Specific Alternative Splicing
1999
Site-Specific Phosphorylation of IκBα by a Novel Ubiquitination-Dependent Protein Kinase Activity
1996
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Purification of Active Calpain by Affinity Chromatography on an Immobilized Peptide Inhibitor
1996
Functional Properties of Recombinant Calpain I and of Mutants Lacking Domains III and IV of the Catalytic Subunit
1997
Regulation of IκBβ Degradation
1997
Regulated nuclear import of Rel proteins in the Drosophila immune response
1998 Nature
Regulating protein degradation by ubiquitination
1997
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
A ubiquitin-like system mediates protein lipidation
2000 StandoutNatureNobel
Constitutive Apoptosis in Human Neutrophils Requires Synergy between Calpains and the Proteasome Downstream of Caspases
1998
Nuclear protein localization
1991
Changes in calpain and calpastatin mRNA induced by β‐adrenergic stimulation of bovine skeletal muscle
1992
Site-specific Tyrosine Phosphorylation of IκBα Negatively Regulates Its Inducible Phosphorylation and Degradation
1996
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
The sensitivity of c-Jun and c-Fos proteins to calpains depends on conformational determinants of the monomers and not on formation of dimers
1999
Transcriptional regulation of the human interleukin-6 gene promoter in human T-cell leukemia virus type I-infected T-cell lines: evidence for the involvement of NF-kappa B
1994
Decreased susceptibility to calpains of v -FosFBR but not of v -FosFBJ or v -JunASV17 retroviral proteins compared with their cellular counterparts
1997
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Association of calpain (Ca2+-dependent thiol protease) with its endogenous inhibitor calpastatin in myoblasts
1999
CalpA, a Drosophila Calpain Homolog Specifically Expressed in a Small Set of Nerve, Midgut, and Blood Cells
1995
Degradation of Proteins with Acetylated Amino Termini by the Ubiquitin System
1989 StandoutScienceNobel
Non-erythroid α-spectrin breakdown by calpain and interleukin 1 β-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis
1996
Human Immunodeficiency Virus Induces a Dual Regulation of Bcl-2, Resulting in Persistent Infection of CD4+T- or Monocytic Cell Lines
1998 StandoutNobel
Biologically active monomeric and heterodimeric recombinant human calpain I produced using the baculovirus expression system
1996
Cactus protein degradation mediates Drosophila dorsal-ventral signaling.
1995
Modulation of RNA editing by functional nucleolar sequestration of ADAR2
2003
Proteasome regulation of activation-induced T cell death
1997 StandoutNobel
Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination.
1995
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
v-Src-Induced Modulation of the Calpain-Calpastatin Proteolytic System Regulates Transformation
2002
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Calpain Activation Contributes to Dendritic Remodeling after Brief Excitotoxic InjuryIn Vitro
1997
Calpain inhibitors as potential treatment for stroke and other neurodegenerative diseases: recent trends and developments
1998
Karyopherin β2 mediates nuclear import of a mRNA binding protein
1997 StandoutNobel
Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene.
1994
N- and C-Terminal Sequences Control Degradation of MAD3/IκBα in Response to Inducers of NF-κB Activity
1995
Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis
1998
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.
1995
A CONSERVED SIGNALING PATHWAY: The Drosophila Toll-Dorsal Pathway
1996
Analysis of arginine-rich peptides from the HIV Tat protein reveals unusual features of RNA-protein recognition.
1991
Calpain Regulates Actin Remodeling during Cell Spreading
1998
A putative mechanism of demyelination in multiple sclerosis by a proteolytic enzyme, calpain
1999
The Calpain System
2003 Standout
HTLV-1 p27rex stabilizes human interleukin-2 receptor alpha chain mRNA.
1990 StandoutNobel
A nuclear localization domain in the hnRNP A1 protein.
1995
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
Neural Science
2000 StandoutNobel
Structure and physiological function of calpains
1997
Constitutive Phosphorylation of IκBα by Casein Kinase II Occurs Preferentially at Serine 293: Requirement for Degradation of Free IκBα
1996
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Proteolysis by Calpains: a Possible Contribution to Degradation of p53
1997
Immunological defects in mice with a targeted disruption in Bcl-3.
1997
NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses
1998 Standout
Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli.
1995
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
Proteasomes play an essential role in thymocyte apoptosis.
1996
Activation of the cell death program by inhibition of proteasome function
1997
Phosphorylation and subcellular distribution of calpastatin in human hematopoietic system cells
1991
Ischemic Cell Death in Brain Neurons
1999 Standout
Regulation of Interferon-γ-Activated STAT1 by the Ubiquitin-Proteasome Pathway
1996 Science
Binding of calpain fragments to calpastatin
1991
Correction of Radiation Sensitivity in Ataxia Telangiectasia Cells by a Truncated IκB-α
1995 Science
Roles of individual EF-hands in the activation of m-calpain by calcium
2000
Constitutive Expression of Bcl-3 in Thymocytes Increases the DNA Binding of NF-κB1 (p50) Homodimers In Vivo
1996
Nuclear and nucleolar targeting of human ribosomal protein S6.
1995
The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium
2000 Nobel
Effect of Ca2+ on binding of the calpains to calpastatin
1989
Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†
1996
THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
1996 Standout
Proteasome inhibitors: valuable new tools for cell biologists
1998
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
A 1.3-Å resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation
1998 StandoutNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Altered ubiquitination and stability of aquaporin-1 in hypertonic stress
2001 StandoutNobel
Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B.
1996 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Suppression of TNF-α-Induced Apoptosis by NF-κB
1996 StandoutScience
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
2004 StandoutNobel
Human T-Cell Leukemia Virus Type I Tax Activation of NF-ΝB/Rel Involves Phosphorylation and Degradation of IΙBκ and RelA (p65)-Mediated Induction of the italic toc-rel Gene
1994
Inactivation of IκBβ by the Tax Protein of Human T-Cell Leukemia Virus Type 1: a Potential Mechanism for Constitutive Induction of NF-κB
1996
Suppression of okadaic acid‐induced apoptosis by overexpression of calpastatin in human UVr‐1 cells
1999
Specific Increase in Amyloid β-Protein 42 Secretion Ratio by Calpain Inhibition
1997 StandoutNobel
Studies of the active site of m-calpain and the interaction with calpastatin
1993
Works of M. Maki being referenced
Four Types of Calpastatin Isoforms with Distinct Amino-Terminal Sequences Are Specified by Alternative First Exons and Differentially Expressed in Mouse Tissues
2000
Calcium-Induced Exposure of a Hydrophobic Surface of Mouse ALG-2, Which Is a Member of the Penta-EF-Hand Protein Family
1998
Assignment of the human calpastatin gene (CAST) to chromosome 5 at region q14→q22
1990
Molecular Diversity of Calpastatin in Human Erythroid Cells
1993
Identification and Characterization of Two Penta-EF-Hand Ca2+-Binding Proteins in Dictyostelium discoideum
2001
Caspases Cleave the Amino-Terminal Calpain Inhibitory Unit of Calpastatin during Apoptosis in Human Jurkat T Cells
2000
An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective.
1996
Molecular diversity of erythrocyte calpastatin.
1991
Expression of calpain II gene in human hematopoietic system cells infected with human T-cell leukemia virus type I.
1992
Calpastatins: biochemical and molecular biological studies.
1991
Amino-terminal conserved region in proteinase inhibitor domain of calpastatin potentiates its calpain inhibitory activity by interacting with calmodulin-like domain of the proteinase.
1994
Effects of a highly basic region of human immunodeficiency virus Tat protein on nucleolar localization
1990
Molecular diversity in amino-terminal domains of human calpastatin by exon skipping.
1992
Analysis of calcium-dependent interaction between amino-terminal conserved region of calpastatin functional domain and calmodulin-like domain of mu-calpain large subunit.
1994
Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro.
1990
Analysis of structure-function relationship of pig calpastatin by expression of mutated cDNAs in Escherichia coli.
1988
Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B.
1994
Factors influencing the binding of calpain I to human erythrocyte inside-out vesicles.
1990
Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.
1996
Inhibition of calpain by a synthetic oligopeptide corresponding to an exon of the human calpastatin gene
1989