Citation Impact

Citing Papers

Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
1994 StandoutNature
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2
1996
Prostaglandin Endoperoxide H Synthases-1 and -2
1996
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
1999 StandoutNature
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2
2000
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
1999 StandoutNature
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Extracellular ATP and cell signalling
1992
Interleukin 1 and tumour necrosis factor increase phosphorylation of the small heat shock protein
1989
Different Intracellular Locations for Prostaglandin Endoperoxide H Synthase-1 and −2
1995
Immune Response in Stat2 Knockout Mice
2000
Chemoprevention of familial adenomatous polyposis development in the APCmin mouse model by 1,4-phenylene bis(methylene)selenocyanate
2000
IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff
2002
Cyclooxygenase‐2 and its regulation in inflammation
1996
Issues in T‐helper 1 development – resolved and unresolved
2004
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.
1998 StandoutNobel
Serine phosphorylation of STATs
2000
Cardiovascular Risk Associated with Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention
2005 Standout
The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β
1998 StandoutNature
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential
2006
Functions of intermediate filaments in neuronal development and disease
2003
STAT proteins and transcriptional responses to extracellular signals
2000
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Gastrointestinal Toxicity With Celecoxib vs Nonsteroidal Anti-inflammatory Drugs for Osteoarthritis and Rheumatoid Arthritis
2000 Standout
The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase
1995
The Role of Oxidative Stress in Diabetic Complications
2005
Hemodynamic Shear Stress and Its Role in Atherosclerosis
1999 Standout
Cyclooxygenase‐2 modulates cellular growth and promotes tumorigenesis
2003
Prostaglandin endoperoxide synthases-1 and -2
1995
Cyclo-Oxygenase Isoenzymes
1997
Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production.
1997
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2
1996 Standout
Tumor necrosis factor-α induces the phosphorylation of 28kDa stress proteins in endothelial cells: Possible role in protection against cytotoxicity?
1989
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
1996 StandoutNature
Cytokine Signaling in 2002
2002 Standout
Prostaglandin synthase 2
1996 Standout
Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin
2001 Standout
Role of Val509 in Time-dependent Inhibition of Human Prostaglandin H Synthase-2 Cyclooxygenase Activity by Isoform-selective Agents
1996
Regulation of Interferon‐γ During Innate and Adaptive Immune Responses
2007
Involvement of Arginine 120, Glutamate 524, and Tyrosine 355 in the Binding of Arachidonate and 2-Phenylpropionic Acid Inhibitors to the Cyclooxygenase Active Site of Ovine Prostaglandin Endoperoxide H Synthase-1
1996
Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis
2003 StandoutNature
Amyotrophic Lateral Sclerosis
2001 Standout
The V Protein of Human Parainfluenza Virus 2 Antagonizes Type I Interferon Responses by Destabilizing Signal Transducer and Activator of Transcription 2
2001
Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-[125I]iodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site
1996
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
The Catalytic Outcomes of the Constitutive and the Mitogen Inducible Isoforms of Prostaglandin H2 Synthase Are Markedly Affected by Glutathione and Glutathione Peroxidase(s)
1995
Arginine 120 of Prostaglandin G/H Synthase-1 Is Required for the Inhibition by Nonsteroidal Anti-inflammatory Drugs Containing a Carboxylic Acid Moiety
1995
Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1
2003
Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides
1993
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Phosphorylation of the small heat-shock protein is regulated by interleukin 1, tumour necrosis factor, growth factors, bradykinin and ATP
1991
Aspirin-like Molecules that Covalently Inactivate Cyclooxygenase-2
1998 Science
Expression cloning of an ATP receptor from mouse neuroblastoma cells.
1993 StandoutNobel
Structural and Functional Basis of Cyclooxygenase Inhibition
2007
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-α/β on antigen cross-presentation
2006 StandoutNobel
Functional Arteries Grown in Vitro
1999 StandoutScience
Inhibitor-Induced Changes in the Intrinsic Fluorescence of Human Cyclooxygenase-2
1996
Kinetic basis for selective inhibition of cyclo-oxygenases
1999
Prostaglandin endoperoxide synthase: structure and catalysis
1991
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
P2 purinoceptors on vascular endotheliai cells: physiological significance and transduction mechanisms
1990
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
The Cyclooxygenase Reaction Mechanism
2002
CYCLOOXYGENASES 1 AND 2
1998 StandoutNobel
Cell locomotion and focal adhesions are regulated by substrate flexibility
1997 Standout
d - myo -Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways
1997 StandoutNobel
Arachidonic Acid Oxygenation by COX-1 and COX-2
1999
Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes
2016 StandoutNobel
Dendritic cells are specialized accessory cells along with TGF-β for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3− precursors
2007 StandoutNobel
Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis
2011
Growth Factors and Cancer
1991 StandoutScience
Role of Metazoan Mediator Proteins in Interferon-Responsive Transcription
2003
Phosphorylation and subcellular translocation of endothelial nitric oxide synthase.
1993
Late Onset Death of Motor Neurons in Mice Overexpressing Wild-Type Peripherin
1999
Selective COX-2 Inhibition Improves Endothelial Function in Coronary Artery Disease
2003
Bradykinin and bombesin rapidly stimulate tyrosine phosphorylation of a 120-kDa group of proteins in Swiss 3T3 cells.
1991
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Heme-Containing Oxygenases
1996 Standout
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Transient up-regulation of P2Y2nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes
1997 StandoutNobel
Metabolism of ubiquitinated histones.
1981 StandoutNobel
Organoselenium and Organotellurium Compounds:  Toxicology and Pharmacology
2004 Standout
Flow-mediated endothelial mechanotransduction
1995 Standout
Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies
2016
Structure and Chemistry of Cytochrome P450
2005 Standout

Works of M. Lecomte being referenced

Selective Inhibition of Prostaglandin Endoperoxide Synthase-1 (Cyclooxygenase-1) by Valerylsalicylic Acid
1995
In vivo effect of 8-epi-PGF2α on retinal circulation in diabetic and non-diabetic rats
1998
Murine Stat2 is uncharacteristically divergent
1999
Pattern of protein phosphorylation in aortic endothelial cells. Modulation by adenine nucleotides and bradykinin.
1988
Transcriptional Activation of the Mouse Peripherin Gene by Leukemia Inhibitory Factor: Involvement of STAT Proteins
1998
Covalent binding of arachidonic acid metabolites to human platelet proteins. Identification of prostaglandin H synthase as one of the modified substrates.
1990
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin.
1994
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