Standout Papers
Citation Impact
Citing Papers
The lattice as allosteric effector: Structural studies of αβ- and γ-tubulin clarify the role of GTP in microtubule assembly
2008
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Evolution of a highly active and enantiospecific metalloenzyme from short peptides
2018 Science
Mechanisms of Viral Membrane Fusion and Its Inhibition
2001
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
2013 Science
Fusion of Cells by Flipped SNAREs
2003 StandoutScienceNobel
Antibody Recognition of a Highly Conserved Influenza Virus Epitope
2009 Science
A TOG:αβ-tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase
2012 Science
Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system
2018
CAPRI: A Critical Assessment of PRedicted Interactions
2003
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid
1988 Nature
Three-dimensional solution structure of the 44kDa ectodomain of SIV gp41
1998
Cation–π interactions in ligand recognition and catalysis
2002
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
Neutralizing antibody to human rhinovirus 14 penetrates the receptor-binding canyon
1996 Nature
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Influenza HA Subtypes Demonstrate Divergent Phenotypes for Cleavage Activation and pH of Fusion: Implications for Host Range and Adaptation
2013
Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli
1989 StandoutNatureNobel
Adaptation of Egg-Grown and Transfectant Influenza Viruses for Growth in Mammalian Cells: Selection of Hemagglutinin Mutants with Elevated pH of Membrane Fusion
1997
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
Refinement of the influenza virus hemagglutinin by simulated annealing
1990
Identification of the residues in human CD4 critical for the binding of HIV
1989 StandoutNobel
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
2009
The Molecular Biology of Influenza Virus Pathogenicity
1988
Structure of Antibody-Antigen Complexes: Implications for Immune Recognition
1988
Atomic structure of the ectodomain from HIV-1 gp41
1997 StandoutNature
Crystal Structure of the Ebola Virus Membrane Fusion Subunit, GP2, from the Envelope Glycoprotein Ectodomain
1998
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
SNAREpins: Minimal Machinery for Membrane Fusion
1998 StandoutNobel
New Insights into the Mechanisms of Cytomotive Actin and Tubulin Filaments
2011
Rapid Evolution of RNA Viruses
1987
Virus versus antibody
1997
Structural Basis of Interprotofilament Interaction and Lateral Deformation of Microtubules
2010
Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo
2014
Reversibility in Fusion Protein Conformational Changes The Intriguing Case of Rhabdovirus-Induced Membrane Fusion
2005
Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives
2006
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Unraveling hot spots in binding interfaces: progress and challenges
2002
Membrane Fusion
2003 StandoutNobel
Antibody-antigen interactions: new structures and new conformational changes
1994
Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and x-ray crystallography
1992
Super-resolution biomolecular crystallography with low-resolution data
2010 StandoutNatureNobel
Glycosylation Governs the Binding of Antipeptide Antibodies to Regions of Hypervariable Amino Acid Sequence within Recombinant gp120 of Human Immunodeficiency Virus Type 1
1990
Nucleotide-Dependent Lateral and Longitudinal Interactions in Microtubules
2013
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Role of Hemagglutinin Cleavage for the Pathogenicity of Influenza Virus
1999
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
Microtubule-binding agents: a dynamic field of cancer therapeutics
2010 Standout
Enveloped viruses: A common mode of membrane fusion?
1997
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly
2005 Nature
Progress in protein–protein docking: Atomic resolution predictions in the CAPRI experiment using RosettaDock with an improved treatment of side‐chain flexibility
2005 StandoutNobel
Structural definition of a conserved neutralization epitope on HIV-1 gp120
2007 Nature
Assessing predictions of protein–protein interaction: The CAPRI experiment
2005
Membrane Fusion by Surrogate Receptor-Bound Influenza Haemagglutinin
1999
Accessory protein regulation of microtubule dynamics throughout the cell cycle
1999
Building machines with DNA molecules
2019
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolution
1992 StandoutNobel
Structural analysis of affinity matured antibodies and laboratory-evolved enzymes
2001
CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast
2000 StandoutNobel
Evolution of Aldolase Antibodies in Vitro : Correlation of Catalytic Activity and Reaction-based Selection
2003
EBs Recognize a Nucleotide-Dependent Structural Cap at Growing Microtubule Ends
2012
Outer Shape of Molecules as Probed by Ground-State Atoms from H to Ar
1997
Crystal Structure of a Catalytic Antibody with a Serine Protease Active Site
1994 Science
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Solvent-Free Organic Synthesis
2000 StandoutNobel
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Electron microscopy of antibody complexes of influenza virus haemagglutinin in the fusion pH conformation.
1995
Structural Basis for Antigen-Antibody Recognition
1986 StandoutScienceNobel
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Influenza hemagglutinin is spring-loaded by a metastable native conformation
1997
Bovine and mouse serum beta inhibitors of influenza A viruses are mannose-binding lectins.
1990
Supramolecular Chemistry: Receptors, Catalysts, and Carriers
1985 StandoutScienceNobel
Inclusion compounds ?Past, present, and future
1983
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
The receptor-binding and membrane-fusion properties of influenza virus variants selected using anti-haemagglutinin monoclonal antibodies.
1987
Electron and X-ray diffraction studies of influenza neuraminidase complexed with monoclonal antibodies
1986
Designed Ankyrin Repeat Proteins (DARPins): Binding Proteins for Research, Diagnostics, and Therapy
2011
Trypsinogen-trypsin transition: a molecular dynamics study of induced conformational change in the activation domain
1987 StandoutNobel
Specificity of antibodies produced against native or desialylated human immunodeficiency virus type 1 recombinant gp160
1993 StandoutNobel
Immune Versus Natural Selection: Antibody Aldolases with Enzymic Rates But Broader Scope
1997 StandoutScienceNobel
Carbohydrate side chains of Rauscher leukemia virus envelope glycoproteins are not required to elicit a neutralizing antibody response
1986
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution.
1996
Adaptive strategies of the influenza virus polymerase for replication in humans
2009 StandoutNobel
Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin
2000 Standout
Crystallographic detection of a second ligand binding site in influenza virus hemagglutinin.
1992
Sialic acids on the surface of caprine arthritis-encephalitis virus define the biological properties of the virus
1988
Rapid selection for an N-linked oligosaccharide by monoclonal antibodies directed against the V3 loop of human immunodeficiency virus type 1
1996
Progress in Modeling of Protein Structures and Interactions
2005 StandoutScienceNobel
Insights into microtubule nucleation from the crystal structure of human γ-tubulin
2005 Nature
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Trapping a transition state in a computationally designed protein bottle
2015 StandoutScienceNobel
Binding Energy and Catalysis: The Implications for Transition-State Analogs and Catalytic Antibodies
1997
From Molecular Diversity to Catalysis: Lessons from the Immune System
1995 Science
Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy
2012
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry
2006 StandoutNobel
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
Sequences of the major antibody binding epitopes of the Indiana serotype of vesicular stomatitis virus
1986
MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments
2002
Genetic Reassortment of Avian, Swine, and Human Influenza A Viruses in American Pigs
1999
Structural insights into key sites of vulnerability on HIV ‐1 Env and influenza HA
2012
Quantum Mechanical Continuum Solvation Models
2005 Standout
Structural origins of efficient proton abstraction from carbon by a catalytic antibody
2005
Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1
1990
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Influence of carbohydrate moieties on the immunogenicity of human immunodeficiency virus type 1 recombinant gp160
1992 StandoutNobel
Critical Analysis of Antibody Catalysis
2000
LAV Revisited: Origins of the Early HIV-1 Isolates from Institut Pasteur
1991 StandoutScienceNobel
Carbohydrate Dramatically Influences Immune Reactivity of Antisera to Viral Glycoprotein Antigens
1984 Science
Membrane fusion mediated by the influenza virus hemagglutinin requires the concerted action of at least three hemagglutinin trimers.
1996
A simple physical model for binding energy hot spots in protein–protein complexes
2002 StandoutNobel
Vesicular Stomatitis Virus G Protein Acquires pH-Independent Fusion Activity during Transport in a Polarized Endometrial Cell Line
1999
Works of M. Knossow being referenced
Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
2009
An Antibody That Prevents the Hemagglutinin Low pH Fusogenic Transition
2002
Stathmin and Interfacial Microtubule Inhibitors Recognize a Naturally Curved Conformation of Tubulin Dimers
2010
Rabies virus glycoprotein is a trimer
1992
The Stathmin/Tubulin Interaction in Vitro
1997
Antigen distortion allows influenza virus to escape neutralization
1998
A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site.
1999
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
2004 StandoutNature
Structural basis for the regulation of tubulin by vinblastine
2005 Nature
The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin
2011
The Binding of Vinca Domain Agents to Tubulin
2010
Membrane Fusion by Influenza Hemagglutinin
1995
Structure of influenza virus haemagglutinin complexed with a neutralizing antibody
1995 Nature
Crystal structure of a catalytic antibody Fab with esterase- like activity
1994
Mechanism of Neutralization of Influenza Virus Infectivity by Antibodies
2002
Structure of a kinesin–tubulin complex and implications for kinesin motility
2013
The 4 Å X-Ray Structure of a Tubulin:Stathmin-like Domain Complex
2000
Cis-trans photoisomerization in a tri-o-thymotide clathrate. Crystal structure of tri-o-thymotide clathrates of cis- and trans-stilbene
1979
Low-pH conformational changes of rabies virus glycoprotein and their role in membrane fusion
1993
Enantiomer recognition and guest-host configurational correlation in crystals of tri-o-thymotide clathrate inclusion compounds
1980
A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody.
1984
Structural evidence for a programmed general base in the active site of a catalytic antibody
2000
Stereospecific reactions and interactions in tri-ortho-thymotide clathrates
1985
Structural Convergence in the Active Sites of a Family of Catalytic Antibodies
1997 Science
A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end
2012
Reversible conformational changes and fusion activity of rabies virus glycoprotein
1991
The refinement of the haemagglutinin membrane glycoprotein of influenza virus
1986
Insight into the PrP C → PrP Sc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants
2004
N-Terminal Stathmin-like Peptides Bind Tubulin and Impede Microtubule Assembly
2005
X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release
1997
Chiral discrimination in crystalline tri-o-thymotide clathrate inclusion complexes. Chemical and crystallographic studies
1983
Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin
1984 Nature
Structural evidence for recognition of a single epitope by two distinct antibodies
2000
Structural insight into the inhibition of tubulin by vinca domain peptide ligands
2008
Crystal structure of the complex of a catalytic antibody Fab fragment with a transition state analog: structural similarities in esterase-like catalytic antibodies.
1995
Kinesin, 30 years later: Recent insights from structural studies
2015