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Placental Transfer of a Hydroxylated Polychlorinated Biphenyl and Effects on Fetal and Maternal Thyroid Hormone Homeostasis in the Rat
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The Role of Selenium in Thyroid Hormone Action*
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THE STATE OF THE ART IN THE 1990’S: NCRP REPORT No. 136 ON THE SCIENTIFIC BASES FOR LINEARITY IN THE DOSE-RESPONSE RELATIONSHIP FOR IONIZING RADIATION
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The Effect of Thyroid Dysfunction and Fasting on Placenta Inner Ring Deiodinase Activity in the Rat*
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Timing of Thyroid Hormone Action in the Developing Brain: Clinical Observations and Experimental Findings
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Kashin–Beck Osteoarthropathy in Rural Tibet in Relation to Selenium and Iodine Status
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2007 Guidelines for the Management of Arterial Hypertension
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The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein
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The Effects and Interactions of Substrates, Inhibitors, and the Cellular Thiol- Disulfide Balance on the Regulation of Type II Iodothyronine 5′-Deiodinase*
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Evolving Concepts in the Pathophysiology, Diagnosis, and Treatment of Pheochromocytoma
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Activation of the Luteinizing Hormone Receptor Following Substitution of Ser-277 with Selective Hydrophobic Residues in the Ectodomain Hinge Region
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Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency.
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Time course of histological progression in primary biliary cirrhosis
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Primary Biliary Cirrhosis
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Plasma Normetanephrine and Metanephrine for Detecting Pheochromocytoma in von Hippel–Lindau Disease and Multiple Endocrine Neoplasia Type 2
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Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*
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Hydralazine may induce autoimmunity by inhibiting extracellular signal–regulated kinase pathway signaling
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A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
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Ursodiol for Primary Sclerosing Cholangitis
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DNA methylation and autoimmune disease
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Iodothyronine Deiodinase Activities in FRTL5 Cells: Predominance of Type I 5′-Deiodinase*
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Inhibition of Pineal Type‐II 5′‐Deiodinase Does Not Affect the Nocturnal Increase of N‐Acetyltransferase Activity and Melatonin Content in Either Euthyroid or Thyroidectomized Rats
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Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein
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Molecular Mechanisms of Amyloidosis
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The Deiodinase Family of Selenoproteins
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DNA methylation and human disease
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Thyroxine 5′-Deiodinase in Human Anterior Pituitary Tumors*
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Myosin V Plays an Essential Role in the Thyroid Hormone-dependent Endocytosis of Type II Iodothyronine 5′-Deiodinase
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Thyroid–Adrenergic Interactions: Physiological and Clinical Implications
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Effect of starvation or treatment with corticosterone on the amount of easily releasable myofilaments in rat skeletal muscles
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The Effects of Amiodarone on Serum Thyroid Hormones and Hepatic Thyroxine 5′-Monodeiodination in Rats*
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Inhibition of rat liver iodothyronine deiodinase. Interaction of aurones with the iodothyronine ligand-binding site.
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Selenium deficiency and type II 5'-deiodinase regulation in the euthyroid and hypothyroid rat: evidence of a direct effect of thyroxine.
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Type 2 Iodothyronine Deiodinase Levels Are Higher in Slow-Twitch than Fast-Twitch Mouse Skeletal Muscle and Are Increased in Hypothyroidism
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The Role of 3,3′,5′-Triiodothyronine in the Regulation of Type II Iodothyronine 5′-Deiodinase in the Rat Cerebral Cortex*
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EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
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Effect of thyroid status on catecholamine stimulation of thyroxine 5'-deiodinase in brown adipocytes
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Sources and quantity of 3,5,3'-triiodothyronine in several tissues of the rat.
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Catalytic Activity of Type II Iodothyronine 5′-Deiodinase Polypeptide Is Dependent upon a Cyclic AMP Activation Factor
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Direct assessment of brown adipose tissue as a site of systemic tri-iodothyronine production in the rat
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Potential of brown adipose tissue type II thyroxine 5'-deiodinase as a local and systemic source of triiodothyronine in rats.
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Current status and performance goals for serum thyrotropin (TSH) assays
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Qualitative and quantitative differences in the pathways of extrathyroidal triiodothyronine generation between euthyroid and hypothyroid rats.
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Effect of Thyroxine Therapy on Serum Lipoproteins in Patients with Mild Thyroid Failure: A Quantitative Review of the Literature
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Thyroid Hormone Metabolism and the Source of Plasma Triiodothyronine in 2-Week-Old Rats: Effects of Thyroid Status*
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The Mammalian Homolog of the Frog Type II Selenodeiodinase Does Not Encode a Functional Enzyme in the Rat*
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Thyroxine targets different pathways of internalization of type II iodothyronine 5'-deiodinase in astrocytes.
1993
Relationships between Circulating and Intracellular Thyroid Hormones: Physiological and Clinical Implications*
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Primary Biliary Cirrhosis
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Type II Iodothyronine 5'-Deiodination by Human and Rat Placenta in Vitro*
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Induction of type III deiodinase activity in astroglial cells by thyroid hormones.
1992
The signal for translational readthrough of a UGA codon in Sindbis virus RNA involves a single cytidine residue immediately downstream of the termination codon
1993 StandoutNobel
Nuclear 3,5,3′-Triiodothyronine (T3) in Brown Adipose Tissue: Receptor Occupancy and Sources of T3as Determined byin VivoTechniques*
1987
The Effects of Propylthiouracil, Iodothyronines, and Other Agents on Thyroid Hormone Metabolism in Human Placenta*
1984
Adrenergic activation of triiodothyronine production in brown adipose tissue
1983 Nature
Amyloid P component. A critical review
1997
Molecular biological and biochemical characterization of the human type 2 selenodeiodinase.
1996
Direct Radioimmunoassay of Nuclear 3,5,3′ Triiodothyronine in Rat Anterior Pituitary
1980
Biosynthesis and function of selenocysteine-containing enzymes.
1991
Metabolic effect of 3,3',5'-triiodothyronine in cultured growth hormone-producing rat pituitary tumor cells. Evidence for a unique mechanism of thyroid hormone action.
1985
Regional Expression of the Type 3 Iodothyronine Deiodinase Messenger Ribonucleic Acid in the Rat Central Nervous System and Its Regulation by Thyroid Hormone*
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Peripheral tissue mechanism for maintenance of serum triiodothyronine values in a thyroxine-deficient state in man.
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Brown Adipose Tissue: Function and Physiological Significance
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Inhibition of type I and type II iodothyronine deiodinase activity in rat liver, kidney and brain produced by selenium deficiency
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Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis.
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Long-Term Outcomes of Surgical Treatment for Hereditary Pheochromocytoma
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SUCCESSFUL OUTCOMES IN PHEOCHROMOCYTOMA SURGERY IN THE MODERN ERA
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The Contribution of Local Tissue Thyroxine Monodeiodination to the Nuclear 3,5,3′- Triiodothyronine in Pituitary, Liver, and Kidney of Euthyroid Rats*
1978
Production rates and turnover of triiodothyronine in rat-developing cerebral cortex and cerebellum. Responses to hypothyroidism.
1984
Different pathways of iodothyronine 5′-deiodination in rat cerebral cortex
1981
Thyroxine-dependent modulation of actin polymerization in cultured astrocytes. A novel, extranuclear action of thyroid hormone.
1990
Investigations on Iodothyronine Deiodinase Activity in the Maturing Rat Brain*
1986
Identification of a 27-kDa Protein with the Properties of Type II Iodothyronine 5‵-Deiodinase in Dibutyryl Cyclic AMP-stimulated Glial Cells
1989
Evidence for Two Pathways of Iodothyronine 5′-Deiodination in Rat Pituitary That Differ in Kinetics, Propylthiouracil Sensitivity, and Response to Hypothyroidism
1983
Thyroid T4 5′-deiodinase activity in normal and abnormal human thyroid glands
1984
Thyroid Hormone Regulation of Metabolism
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Isolated familial pheochromocytoma as a variant of von Hippel-Lindau disease.
1996
Angiotensin II Induces Skeletal Muscle Wasting through Enhanced Protein Degradation and Down-Regulates Autocrine Insulin-Like Growth Factor I*
2001
Pheochromocytoma: State-of-the-Art and Future Prospects
2003
Targeted Disruption of the Type 1 Selenodeiodinase Gene (Dio1) Results in Marked Changes in Thyroid Hormone Economy in Mice
2005
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
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Rat liver iodothyronine monodeiodinase. Evaluation of the iodothyronine ligand-binding site.
1986
Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing
2000
An Analysis of the Sources and Quantity of 3,5,3′-Triiodothyronine Specifically Bound to Nuclear Receptors in Rat Cerebral Cortex and Cerebellum*
1982
Adrenergic modulation of human colonic motor and sensory function
1997
Comparison of thyroxine and 3,3′,5′-triiodothyronine metabolism in rat kidney and liver homogenates
1979
Acute Posttranscriptional Regulation of Cerebrocortical and Pituitary Iodothyronine 5′-Deiodinases by Thyroid Hormone*
1984
Methotrexate Induces Clinical and Histologic Remission in Patients with Refractory Inflammatory Bowel Disease
1989
Frequent Chest X-Ray Fluoroscopy and Breast Cancer Incidence among Tuberculosis Patients in Massachusetts
1991
Current status and performance goals for serum thyroglobulin assays
1996
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Thyroxine 5-deiodinase in human brain tumors.
1993
Current Perspective on the Pathogenesis of Graves’ Disease and Ophthalmopathy
2003
Chemistry of Biologically Important Synthetic Organoselenium Compounds
2001 Standout
Thyroid hormone metabolism in primary cultures of fetal rat brain cells
1985
The Type 2 and Type 3 Iodothyronine Deiodinases Play Important Roles in Coordinating Development in Rana catesbeiana Tadpoles*
1997
Comparison of Iodothyronine 5′-Deiodinase and Other Thyroid-Hormone-dependent Enzyme Activities in the Cerebral Cortex of Hypothyroid Neonatal Rat
1982
Rapid Thyroxine to 3,5,3′-Triiodothyronine Conversion and Nuclear 3,5,3′-Triiodothyronine Binding in Rat Cerebral Cortex and Cerebellum
1980
Are Iodine-Deficient Rats Euthyroid*
1982
Role of the Iodothyronine Deiodinases in the Physiology and Pathophysiology of Thyroid Hormone Action
2012
Limit of blank, limit of detection and limit of quantitation.
2008 Standout
Characteristics of thyroxine 5'-deiodination in cultured human placental cells. Regulation by iodothyronines.
1985
Phenolic and Tyrosyl Ring Deiodination of Iodothyronines in Rat Brain Homogenates
1980
Evidence for Two Tissue-specific Pathways for In Vivo Thyroxine 5′-Deiodination in the Rat
1982
Exogenous corticosterone mimics a late fasting stage in captive Adélie penguins (Pygoscelis adeliae)
2011
Interactions of Persistent Environmental Organohalogens With the Thyroid Hormone System: Mechanisms and Possible Consequences for Animal and Human Health
1998
Interrelationships among thyroxine, growth hormone, and the sympathetic nervous system in the regulation of 5'-iodothyronine deiodinase in rat brown adipose tissue.
1986
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
The actin cytoskeleton mediates the hormonally regulated translocation of type II iodothyronine 5'-deiodinase in astrocytes.
1990
Studies of the Hormonal Regulation of Type 2 5′-Iodothyronine Deiodinase Messenger Ribonucleic Acid in Pituitary Tumor Cells Using Semiquantitative Reverse Transcription-Polymerase Chain Reaction**This work was supported by NIH Grant DK-36256.
1998
C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus
2001 Standout
Thyroid hormone deiodinases in purified primary glial cell cultures
1986
Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes
2006 StandoutScience
Thyroid hormones and 5'-deiodinase in rat brown adipose tissue during fetal life
1989
Effect of Nicotine on Type 2 Deiodinase Activity in Cultured Rat Glial Cells.
1999
Thyroid-Pituitary Interaction
1982
Regulation of Thyroxine 5′-Deiodinase Activity by 3,5,3′-Triiodothyronine in Cultured Rat Anterior Pituitary Cells*
1984
Effects of Amiodarone and Desethylamiodarone on Pituitary Deiodinase Activity and Thyrotropin Secretion in the Rat
1986
Antibody detection by agglutination–PCR (ADAP) enables early diagnosis of HIV infection by oral fluid analysis
2018 StandoutNobel
Thyroid carcinoma
2003 Standout
Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline
2014 Standout
Prevalence of abnormal thyroid function test results in patients with acute medical illnesses
1982
Works of M Kaplan being referenced
Methotrexate improves biochemical tests in patients with primary biliary cirrhosis who respond incompletely to ursodiol
1999
Treatment of primary biliary cirrhosis with low-dose weekly methotrexate
1991
Primary Biliary Cirrhosis Treated with Low-Dose Oral Pulse Methotrexate
1988
A double-blind controlled trial of oral-pulse methotrexate therapy in the treatment of primary sclerosing cholangitis
1994
Autoreactive murine Th1 and Th2 cells kill syngeneic macrophages and induce autoantibodies
2001
Thyroid Nodularity and Chromosome Aberrations Among Women in Areas of High Background Radiation in China
1990
The Clinical Outcome of Prospective Screening for Multiple Endocrine Neoplasia Type 2A
1988
Inhibition of intrapituitary thyroxine to 3.5.3'-triiodothyronine conversion prevents the acute suppression of thyrotropin release by thyroxine in hypothyroid rats.
1979
Starvation in the rat. II. Effect of age and obesity on protein sparing and fuel metabolism
1980
Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex.
1982
American Thyroid Association assessment of current free thyroid hormone and thyrotropin measurements and guidelines for future clinical assays. The Committee on Nomenclature of the American Thyroid Association
1991
Frequency of transient hypothyroxinaemia in low birthweight infants. Potential pitfall for neonatal screening programmes.
1981
Immunoreactivity to Yersinia enterocolitica antigens in patients with autoimmune thyroid disease.
1992
Thyroxine to 3,5,3′-triiodothyronine conversion by rat anterior pituitary and liver
1978
Tissue specificity and serologic reactivity of an autoantigen associated with autoimmune thyroid disease.
1993
Conversion of thyroxine to triiodothyronine in the anterior pituitary gland and the influence of this process on thyroid status.
1984
Inhibition of Human Neutrophil and Pseudomonas Elastases by the Amyloid P-Component: A Constituent of Elastic Fibers and Amyloid Deposits
1988
Physiological and Pharmacological Influences on Thyroxine to 3,5,3′-Triiodothyronine Conversion and Nuclear 3,5,3′-Triiodothyronine Binding in Rat Anterior Pituitary
1979