Citation Impact
Citing Papers
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
2005 StandoutNobel
Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein
2000 StandoutNobel
Oxygen-regulated and Transactivating Domains in Endothelial PAS Protein 1: Comparison with Hypoxia-inducible Factor-1α
1999 StandoutNobel
Src-mediated Tyrosine Phosphorylation of Dynamin Is Required for β2-Adrenergic Receptor Internalization and Mitogen-activated Protein Kinase Signaling
1999 StandoutNobel
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
1997 StandoutNature
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
Spatio-temporal Dynamics of Protein Kinase B/Akt Signaling Revealed by a Genetically Encoded Fluorescent Reporter
2004 StandoutNobel
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
2002 StandoutNatureNobel
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
Identification of a signal for rapid export of proteins from the nucleus
1995 StandoutNobel
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Extracellular Signal-regulated Kinase and the Small GTP-binding Protein, Rac, Contribute to the Effects of Transforming Growth Factor-β1 on Gene Expression
1996
Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit
1997 StandoutNobel
Cytoplasmic anchoring proteins and the control of nuclear localization
1989 StandoutNobel
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 StandoutNature
Insulin Stimulates Hypoxia-inducible Factor 1 through a Phosphatidylinositol 3-Kinase/Target of Rapamycin-dependent Signaling Pathway
2002 StandoutNobel
Signal transduction by receptors with tyrosine kinase activity
1990 Standout
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
1997 StandoutNature
Gβγ Subunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor
1995 StandoutNobel
Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia
1998
Role of abnormal free fatty acid metabolism in the development of non-insulin-dependent diabetes mellitus
1988
Selection and Analysis of a Mutant Cell Line Defective in the Hypoxia-inducible Factor-1 α-Subunit (HIF-1α)
1998 StandoutNobel
The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization
1989 Nobel
Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
2004 StandoutNobel
The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor
2000 StandoutNobel
Receptor-Mediated Endocytosis and Lysosomal Processing of Insulin-Like Growth Factor I by Mitogenically Responsive Cells*
1988
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
2001 StandoutNobel
Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family
2002 StandoutNobel
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
2007 StandoutNobel
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
β-Arrestins Regulate Mitogenic Signaling and Clathrin-mediated Endocytosis of the Insulin-like Growth Factor I Receptor
1998 StandoutNobel
Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4.
1992
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α
1998 StandoutNobel
Pretranslational Suppression of an Insulin-Responsive Glucose Transporter in Rats with Diabetes Mellitus
1989 Science
Cellular alterations in liver, skeletal muscle, and adipose tissue responsible for insulin resistance in obesity and type II diabetes
1989
Insulin-like Growth Factor-I Receptor Internalization Regulates Signaling via the Shc/Mitogen-activated Protein Kinase Pathway, but Not the Insulin Receptor Substrate-1 Pathway
1998
Mechanisms of Signal Transduction to the Cell Nucleus
1990
The Retinoblastoma Protein Binds to a Family of E2F Transcription Factors
1993
Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): A potential regulatory mechanism for PDK-1 function
2003
Corticosteroids as long-term regulators of the insulin effectiveness in mouse 3T3 adipocytes
1985
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
The Role of Vitamin D and Calcium in Type 2 Diabetes. A Systematic Review and Meta-Analysis
2007 Standout
beta-Adrenergic regulation of insulin and epidermal growth factor receptors in rat adipocytes.
1983
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Induction of Chronic Myelogenous Leukemia in Mice by the P210 bcr/abl Gene of the Philadelphia Chromosome
1990 StandoutScienceNobel
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution.
1986 StandoutNobel
Agouti regulation of intracellular calcium: role in the insulin resistance of viable yellow mice.
1995
The retinoblastoma protein binds to a family of E2F transcription factors.
1993
The Insulin-Sensitive Glucose Transporter
1992
Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ
2001 StandoutScience
After Insulin Binds
1987 Science
Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur.
1995
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.
1993
The matrix Gla protein gene is a marker of the chondrogenesis cell lineage during mouse development
1995
Do agonists promote rapid internalization of beta-adrenergic receptors?
1985
A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis.
1987
Insulin activation of insulin receptor tyrosine kinase in intact rat adipocytes. An in vitro system to measure histone kinase activity of insulin receptors activated in vivo.
1986
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes.
1990 StandoutNobel
Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis
2002 StandoutNobel
Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal.
1990 StandoutNobel
Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein
1997 StandoutScience
Isolation and functional expression of a mammalian prohormone processing enzyme, murine prohormone convertase 1.
1991 StandoutNobel
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily
1995 StandoutScience
Inhibition of E2F-1 Transactivation by Direct Binding of the Retinoblastoma Protein
1993
Prohormone processing in Xenopus oocytes: characterization of cleavage signals and cleavage enzymes.
1991 StandoutNobel
Stimulation of RNA and Protein Synthesis by Intracellular Insulin
1988 Science
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
2000 StandoutNobel
Works of M Kao being referenced
Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemia.
1988
The existence of an optimal range of cytosolic free calcium for insulin-stimulated glucose transport in rat adipocytes.
1987
Thyroid Hormone Regulates the Mouse Thyrotropin β-Subunit Gene Promoter in Transfected Primary Thyrotropes
1989
Surface binding and rates of internalization of 125I-insulin in adipocytes and IM-9 lymphocytes.
1982
Effects of prednisolone and dexamethasone in vivo and in vitro: Studies of insulin binding, deoxyglucose uptake and glucose oxidation in rat adipocytes
1981
Nuclear translocation of the insulin receptor. A possible mediator of insulin's long term effects.
1987
Role of Glucose Transport in the Postreceptor Defect of Non-insulin-dependent Diabetes Mellitus
1982