Citation Impact
Citing Papers
Comparison of Two Fluid-Management Strategies in Acute Lung Injury
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Derivation and Prospective Validation of a Simple Index for Prediction of Cardiac Risk of Major Noncardiac Surgery
1999 Standout
Evidence for the involvement of the μ but not δ opioid receptor subtype in the synergistic interaction between opioid and α2 adrenergic antinociception in the rat spinal cord
1992
Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult
2002 Standout
Effects of Intravenous Patient-Controlled Analgesia with Morphine, Continuous Epidural Analgesia, and Continuous Three-in-One Block on Postoperative Pain and Knee Rehabilitation After Unilateral Total Knee Arthroplasty
1998 Standout
Epidural Clonidine Decreases Postoperative Requirements for Epidural Fentanyl
1993
EXTRADURAL CLONIDINE INFUSIONS FOR ANALGESIA AFTER TOTAL HIP REPLACEMENT
1992
Effects of intrathecal clonidine on duration of bupivacaine spinal anaesthesia, haemodynamics, and postoperative analgesia in patients undergoing knee arthroscopy
1994
The effect of clonidine on intra‐operative requirements of fentanyl during combined epidural/general anaesthesia
1994
British Thoracic Society guideline for diagnostic flexible bronchoscopy in adults: accredited by NICE
2013 Standout
Comparison of the effects of adrenaline, clonidine and ketamine on the duration of caudal analgesia produced by bupivacaine in children
1995
Intraoperative clonidine enhances postoperative morphine patient-controlled analgesia
1992
Anaesthesia, surgery, and challenges in postoperative recovery
2003 Standout
Sedation in outpatient bronchoscopy
2000
A Minimum Dose of Clonidine Added to Mepivacaine Prolongs the Duration of Anesthesia and Analgesia After Axillary Brachial Plexus Block
1996
Gender variations in clinical pain experience
1996 Standout
The Effects of Increasing Plasma Concentrations of Dexmedetomidine in Humans
2000 Standout
Oral clonidine reduces postoperative PCA morphine requirements
1996
Safety and efficacy of postoperative epidural analgesia
2001
Comparison of a bupivacaine-clonidine mixture with plain bupivacaine for caudal analgesia in children † †This paper was presented in part to the North East Thames Region Anaesthetists Society Meeting, April 24, 1993.
1994
Epidural clonidine analgesia for intractable cancer pain
1995
Ventilatory effects of epidural clonidine during the first 3 hours after caesarean section
1992
Meta-analysis of the efficacy of extradural clonidine to relieve postoperative pain: an impossible task
1998
Adrenergic α2C-Receptors Modulate the Acoustic Startle Reflex, Prepulse Inhibition, and Aggression in Mice
1998 StandoutNobel
On the role of the dorsal noradrenergic bundle in learning and habituation to novelty
1988
Child abuse: Adolescent records vs. adult recall
1990 Standout
Effects of Perioperative Dexmedetomidine Infusion in Patients Undergoing Vascular Surgery
1995
Chapter 19 The determinants of stress-induced activation of the prefrontal cortical dopamine system
1991
Effect of Atenolol on Mortality and Cardiovascular Morbidity after Noncardiac Surgery
1996 Standout
The enduring effects of abuse and related adverse experiences in childhood
2005 Standout
Central α2-adrenoceptors are highly stereoselective for dexmedetomidine, the dextro enantiomer of medetomidine
1991
Patient‐controlled epidural analgesia with sufentanil following Caesarean section: the effect of adrenaline and clonidine admixture
1994
Descending control of pain
2002 Standout
SINGLE-DOSE, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY CROSS-OVER COMPARISON OF EXTRADURAL AND I.V. CLONIDINE IN CHRONIC PAIN
1993
Neural regulation of endocrine and autonomic stress responses
2009 Standout
Analgesic and Hemodynamic Effects of Epidural Clonidine, Clonidine/Morphine, and Morphine After Pancreatic Surgery--A Double-Blind Study
1995
ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy)
2009 Standout
The right ventricle: anatomy, physiology, and clinical importance
1991
Fine structure of noradrenergic terminals and their synapses in the rat spinal dorsal horn: an immunohistochemical study
1990
Cerebrospinal fluid kinetics of epidural clonidine in man
1992
Pharmacologic Myocardial Protection in Patients Undergoing Noncardiac Surgery: A Quantitative Systematic Review
2003
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
2003 Standout
CLONIDINE IN THE TREATMENT OF ALCOHOL WITHDRAWAL IN THE INTENSIVE CARE UNIT
1992
Effect of Mechanical Ventilation on Inflammatory Mediators in Patients With Acute Respiratory Distress Syndrome
1999 Standout
Alpha2‐adrenergic agents in anaesthesia
1993
CLONIDINE: UNDERSTANDING ITS DISPOSITION, SITES AND MECHANISM OF ACTION
1987
Wirksamkeit und Nebenwirkungen von Opioiden und α2-Adrenozeptoragonisten in der therapie postoperativer Schmerzen
1992
Multimodal strategies to improve surgical outcome
2002 Standout
THE STRESS RESPONSE OF CRITICAL ILLNESS
1999
Primary pulmonary hypertension
1988
Epidemiology of the adverse hemodynamic events occurring during “clonidine anesthesia”: A prospective open trial of intraoperative intravenous clonidine
1995
Effects of dexmedetomidine on systemic and coronary hemodynamics in the anesthetized dog
1993
Comparison of epidural sufentanil plus clonidine with sufentanil alone for postoperative pain relief
1990
The stress response to trauma and surgery
2000 Standout
α2-Adrenergic Agonists for Regional Anesthesia
1996 Standout
Intrathecal α2-Adrenergic Agonists Stimulate Acetylcholine and Norepinephrine Release from the Spinal Cord Dorsal Horn in Sheep
1997
Therapeutic potential of β-arrestin- and G protein-biased agonists
2010 StandoutNobel
Antithrombotic Therapy for VTE Disease
2012 Standout
Acute kidney injury
2019 Standout
β-Blockers and Reduction of Cardiac Events in Noncardiac Surgery
2002
Pharmacokinetics of clonidine after epidural administration in surgical patients. Lack of correlation between plasma concentration and analgesia and blood pressure changes
1992
Estimating anesthetic depth by electroencephalography during anesthetic induction and intubation in patients undergoing cardiac surgery
1990
Stress signalling pathways that impair prefrontal cortex structure and function
2009 Standout
INTEGRATIVE ROLE OF THE LAMINA TERMINALIS IN THE REGULATION OF CARDIOVASCULAR AND BODY FLUID HOMEOSTASIS
1996
COMPARISON OF 0.125% BUPIVACAINE WITH 0.125% BUPIVACAINE AND CLONIDINE AS EXTRADURAL ANALGESIA IN THE FIRST STAGE OF LABOUR
1993
α2C-Adrenoceptor-Overexpressing Mice Are Impaired in Executing Nonspatial and Spatial Escape Strategies
1998 StandoutNobel
Major Pulmonary Embolism
2002
α-Adrenoceptors
1994
Behavioral and neurochemical characterization of α2A-adrenergic receptor knockout mice
2002 StandoutNobel
Monoaminergic control of the release of calcitonin gene-related peptide- and substance P-like materials from rat spinal cord slices
1993
PREVENTION OF TOURNIQUET PAIN BY SPINAL ISOBARIC BUPIVACAINE WITH CLONIDINE
1989
Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity
1991 Standout
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*
2006 Standout
The pharmacology of the efferent function of sensory nerves.
1991
Clinical Pharmacology of Tramadol
2004 Standout
Third Universal Definition of Myocardial Infarction
2012 Standout
In vivo voltammetry—Present electrodes and methods
1988
A Primer for EEG Signal Processing in Anesthesia
1998 Standout
Assessment of the role of α2‐adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice
1997
Increased Survival of ARDS Patients with Severe Hypoxemia (ECMO Criteria)
1991
The Effect of High Doses of Calcium-Channel Blockers on Survival in Primary Pulmonary Hypertension
1992 Standout
d-amphetamine and l-5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the α2C-adrenergic receptor subtype
1998 StandoutNobel
Evidence for nonsynaptic serotonergic and noradrenergic innervation of the rat dorsal horn and possible involvement of neuron-glia interactions
1993
Enhancement of pressor response to intravenous phenylephrine following oral clonidine medication in awake and anaesthetized patients
1995
The Neuroendocrinology of Thirst and Salt Appetite: Visceral Sensory Signals and Mechanisms of Central Integration
1997
Small, Oral Dose of Clonidine Reduces the Incidence of Intraoperative Myocardial Ischemia in Patients Having Vascular Surgery
1996
The effects of intravenous clonidine on ventilation
1991
Clonidine premedication for coronary artery bypass grafting under high-dose alfentanil anesthesia: Intraoperative and postoperative hemodynamic study
1993
Studies on the origin of rat hippocampal dihydroxyphenylacetic acid using microdialysis
1992
Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine
2014 Standout
Cholinergic, noradrenergic, and serotonergic inhibition of fast synaptic transmission in spinal lumbar dorsal horn of rat
2001
Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat
1992
Sympatholytic and Minimum Anesthetic Concentration-sparing Responses are Preserved in Rats Rendered Tolerant to the Hypnotic and Analgesic Action of Dexmedetomidine, a Selective α2-adrenergic Agonist
1996
Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography
2010 Standout
Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications:
2003
Treatment of canine permeability pulmonary edema: short-term effects of dobutamine, furosemide, and hydralazine.
1985
ACC/AHA 2005 Practice Guidelines for the Management of Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic)
2006 Standout
Severe Neurological Complications after Central Neuraxial Blockades in Sweden 1990–1999
2004 Standout
Histological Analysis of Coronary Artery Lesions in Fatal Postoperative Myocardial Infarction
1999
Midbrain Periaqueductal Gray (PAG) Inhibits Nociceptive Inputs to Sacral Dorsal Horn Nociceptive Neurons Through α2-Adrenergic Receptors
1998
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Cardiovascular Regulation in Mice Lacking α 2 -Adrenergic Receptor Subtypes b and c
1996 StandoutScienceNobel
Vanilloid (Capsaicin) Receptors and Mechanisms
1999 Standout
Comparison of the Effects of Adrenaline, Clonidine, and Ketamine on the Duration of Caudal Analgesia Produced by Bupivacaine in Children
1996
Respiratory variations in right atrial pressure predict the response to fluid challenge
1992
Sepsis‐induced acute kidney injury: A disease of the microcirculation
2018
A Minimum Dose of Clonidine Added to Mepivacaine Prolongs the Duration of Anesthesia and Analgesia After Axillary Brachial Plexus Block
1996
α2-Adrenoceptor modulation of nociception in rat spinal cord: location, effects and interactions with morphine
1987
Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2BAdrenoceptors
2000 StandoutNobel
Dexmedetomidine as an Anesthetic Adjunct in Coronary Artery Bypass Grafting
1997
Right Ventricular Function in Cardiovascular Disease, Part I
2008 Standout
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
INSIGHTS FROM IN VIVO MODIFICATION OF ADRENERGIC RECEPTOR GENE EXPRESSION
1998 StandoutNobel
AN INTEGRATIVE THEORY OF LOCUS COERULEUS-NOREPINEPHRINE FUNCTION: Adaptive Gain and Optimal Performance
2005 Standout
Evidence-Based Surgical Care and the Evolution of Fast-Track Surgery
2008 Standout
Oxygen measurements in brain stem slices exposed to normobaric hyperoxia and hyperbaric oxygen
2001 StandoutNobel
Works of M. Ghignone being referenced
Treatment of Canine Low Pressure Pulmonary Edema
2015
POSTOPERATIVE ANALGESIA WITH EXTRADURAL CLONIDINE
1989
Clonidine for Major Vascular Surgery in Hypertensive Patients
1996
Baroreflex-linked variations of catecholamine metabolism in the caudal ventrolateral medulla: an in vivo electrochemical study
1987
Aortic surgery: effect of clonidine on intraoperative catecholaminergic and circulatory stability
1990
Clonidine for Major Vascular Surgery in Hypertensive Patients
1996
Postoperative Analgesia with Extradural Clonidine
1990
Hemodynamic Management in the Adult Respiratory Distress Syndrome
1983
Dexmedetomidine and Clonidine
2011
Anesthesia for ophthalmic surgery in the elderly: the effects of clonidine on intraocular pressure, perioperative hemodynamics, and anesthetic requirement.
1988
Effects of Clonidine on Narcotic Requirements and Hemodynamic Response during Induction of Fentanyl Anesthesia and Endotracheal Intubation
1986
Treatment of right ventricular dysfunction in acute respiratory failure
1983
EPIDURAL CLONIDINE PRODUCES POSTOPERATIVE ANALGESIA
1988
Effect of increased pulmonary vascular resistance on right ventricular systolic performance in dogs
1984
Clonidine modulates locus coeruleus metabolic hyperactivity induced by stress in behaving rats
1986
Volume Expansion versus Norepinephrine in Treatment of a Low Cardiac Output Complicating an Acute Increase in Right Ventricular Afterload in Dogs
1984
Anesthesia for Ophthalmic Surgery in the Elderly
1988
Increased pressor response to noradrenaline during septic shock following clonidine?
2010
Anesthesia and hypertension: the effect of clonidine on perioperative hemodynamics and isoflurane requirements.
1987
Anesthesia and Hypertension
1987
Catecholamine metabolism in the rat locus coeruleus as studied by in vivo differential pulse voltammetry. III. Evidence for the existence of an α2-adrenergic tonic inhibition in behaving rats
1986
Presynaptic effect of clonidine on unmyelinated afferent fibers in the spinal cord of the cat
1986
Effect of clonidine on haemodynamic responses to endotracheal intubation and on gastric acidity
1987
The Ability of the α2-Adrenergic Agonist Clonidine to Suppress Central Noradrenergic Hyperactivity Secondary to Hemodynamic or Environmental Stimuli
1986