Standout Papers
Citation Impact
Citing Papers
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
Controlling Macromolecular Topology with Genetically Encoded SpyTag–SpyCatcher Chemistry
2013 StandoutNobel
Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility
2021 StandoutNobel
Ubiquitin-binding domains
2006
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution
2010
The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
2008 StandoutScience
The Crystal Structure of Atg3, an Autophagy-related Ubiquitin Carrier Protein (E2) Enzyme that Mediates Atg8 Lipidation
2007 StandoutNobel
The Structure of the 26S Proteasome Subunit Rpn2 Reveals Its PC Repeat Domain as a Closed Toroid of Two Concentric α-Helical Rings
2012
Transferring substrates to the 26S proteasome
2003
Chromatin Modifications and Their Function
2007 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Functional Overlap between eIF4G Isoforms in Saccharomyces cerevisiae
2010 StandoutNobel
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit
2006 StandoutNobel
Investigating the importance of proteasome-interaction for Rad23 function
2002
The 26S proteasome: assembly and function of a destructive machine
2010
Amiloride-blockable sodium currents in isolated taste receptor cells
1988
The hPLIC Proteins May Provide a Link between the Ubiquitination Machinery and the Proteasome
2000
Interactions of PAN's C‐termini with archaeal 20S proteasome and implications for the eukaryotic proteasome–ATPase interactions
2009
Origin and function of ubiquitin-like proteins
2009 Nature
A candidate taste receptor gene near a sweet taste locus
2001 StandoutNobel
Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement
2015 StandoutNobel
Receptor oligomerization guides pathway choice between proteasomal and autophagic degradation
2017
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
Ubiquitination of β-Arrestin Links Seven-transmembrane Receptor Endocytosis and ERK Activation
2007 StandoutNobel
Accurate Protein Complex Retrieval by Affinity Enrichment Mass Spectrometry (AE-MS) Rather than Affinity Purification Mass Spectrometry (AP-MS)
2014
Identification of ubiquitin-like protein-binding subunits of the 26S proteasome
2002
Autophagy: Renovation of Cells and Tissues
2011 Standout
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
2019 StandoutNobel
Ubiquitin Ligase Activity of TFIIH and the Transcriptional Response to DNA Damage
2005 StandoutNobel
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
2013 StandoutNobel
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
2010 Standout
PCI Complexes: Beyond the Proteasome, CSN, and eIF3 Troika
2009
Rad23 escapes degradation because it lacks a proteasome initiation region
2011
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Physiological pH and Acidic Phospholipids Contribute to Substrate Specificity in Lipidation of Atg8
2008 StandoutNobel
The Perseus computational platform for comprehensive analysis of (prote)omics data
2016 Standout
Complete subunit architecture of the proteasome regulatory particle
2012 Nature
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
A Genetic Interaction Map of RNA-Processing Factors Reveals Links between Sem1/Dss1-Containing Complexes and mRNA Export and Splicing
2008
Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldase
2013
Multiubiquitin Chain Receptors Define a Layer of Substrate Selectivity in the Ubiquitin-Proteasome System
2004
Ubiquitin and its kin: how close are the family ties?
2000
The receptors and cells for mammalian taste
2006 StandoutNature
Formation of an Intricate Helical Bundle Dictates the Assembly of the 26S Proteasome Lid
2013
Multiple Associated Proteins Regulate Proteasome Structure and Function
2002
Integrator, a Multiprotein Mediator of Small Nuclear RNA Processing, Associates with the C-Terminal Repeat of RNA Polymerase II
2005
Autophagy and Aging
2011 Standout
Regulation of proteasome assembly and activity in health and disease
2018
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival
2017
Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
2007 StandoutNobel
A Bioorthogonal Reaction of N‐Oxide and Boron Reagents
2015 StandoutNobel
Proteasome Activators
2011
Ubiquitin and ubiquitin-like proteins as multifunctional signals
2005
The Hallmarks of Aging
2013 Standout
Proteasome subunit Rpn1 binds ubiquitin-like protein domains
2002
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
The DNA repair protein Rad23 is a negative regulator of multi-ubiquitin chain assembly
2000
Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
2012
Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex
2009 StandoutNobel
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Diverse polyubiquitin interaction properties of ubiquitin-associated domains
2005
Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
2009
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
2010 Nature
Caspase Activation Inhibits Proteasome Function during Apoptosis
2004 StandoutNobel
The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability
2006
The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress
2003 Standout
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Coping with Protein Quality Control Failure
2017
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
γH2AX and its role in DNA double-strand break repairThis paper is one of a selection of papers published in this Special Issue, entitled 27th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.
2006
Rad23 Promotes the Targeting of Proteolytic Substrates to the Proteasome
2002
Pattern formation outside of equilibrium
1993 Standout
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach
2012
Surface wave mode interactions: effects of symmetry and degeneracy
1989
Structure and Function of the 26S Proteasome
2018
An evolutionarily conserved pathway controls proteasome homeostasis
2016 Nature
Spatial distribution of somatosensory responses evoked by tapping the tongue and finger in man
1980
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Amino acids as taste stimuli. I. Neural and behavioral attributes
1982
Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications
2010
A comprehensive method for detecting ubiquitinated substrates using TR-TUBE
2015
Subunit order of eukaryotic TRiC/CCT chaperonin by cross-linking, mass spectrometry, and combinatorial homology modeling
2012 StandoutNobel
Multifaceted roles of β-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling
2003 StandoutNobel
Evoked Potentials in Clinical Medicine
1982 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
Nonperiodic Activity of the Human Anaphase-Promoting Complex–Cdh1 Ubiquitin Ligase Results in Continuous DNA Synthesis Uncoupled from Mitosis
2000
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
The physiology of plant responses to drought
2020 StandoutScience
Sweet Taste Responses of Mouse Chorda Tympani Neurons: Existence of Gurmarin-Sensitive and -Insensitive Receptor Components
1999
Saccharomyces cerevisiae Putative G Protein, Gtr1p, Which Forms Complexes With Itself and a Novel Protein Designated as Gtr2p, Negatively Regulates the Ran/Gsp1p G Protein Cycle Through Gtr2p
1999
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes
2002
Works of M Funakoshi being referenced
Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasome
2002
Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability
2004
RESPONSES OF TASTE CELLS OF MOUSE
1985
Heterohexameric Ring Arrangement of the Eukaryotic Proteasomal ATPases: Implications for Proteasome Structure and Assembly
2010
A new structural class of proteasome inhibitors identified by microbial screening using yeast-based assay
2003
Xenopus cyclin A1 can associate with Cdc28 in budding yeast, causing cell‐cycle arrest with an abnormal distribution of nuclear DNA
1997 StandoutNobel
Budding yeast Dsk2 protein forms a homodimer via its C-terminal UBA domain
2005
Multiple Assembly Chaperones Govern Biogenesis of the Proteasome Regulatory Particle Base
2009
A multimeric assembly factor controls the formation of alternative 20S proteasomes
2008
Identification of XDRP1; a Xenopus protein related to yeast Dsk2p binds to the N-terminus of cyclin A and inhibits its degradation
1999
Fub1p, a novel protein isolated by boundary screening, binds the proteasome complex
2011
Chaotic behaviour of resonantly forced surface water waves
1987
Summated cerebral evoked responses to taste stimuli in man
1971
Electrophysiological Investigation of the Gustatory Effect of Various Biological Sugars
1962