Standout Papers
- Detection of a Possible Intermediate in Oxidative Phosphorylation (1961)
- Bound Phosphohistidine as an Intermediate in a Phosphorylation Reaction of Oxidative Phosphorylation Catalyzed by Mitochondrial Extracts (1963)
- Identification of Phosphohistidine in Digests from a Probable Intermediate of Oxidative Phosphorylation (1962)
- Firefly luciferase gene: structure and expression in mammalian cells. (1987)
Citation Impact
Citing Papers
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
An avian muscle factor related to MyoD1 activates muscle-specific promoters in nonmuscle cells of different germ-layer origin and in BrdU-treated myoblasts.
1989
The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements
1988
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
A new role for cryptochrome in a Drosophila circadian oscillator
2001 StandoutNatureNobel
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
1992
HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro.
1991
Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements
1997
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells
1990 StandoutNatureNobel
Firefly luciferase as a tool in molecular and cell biology
1988
Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer
1989
Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
1990 Standout
Modulation of firefly luciferase stability and impact on studies of gene regulation
1991
Allergy‐associated Iϵ and Fcϵ receptor II (CD23b) genes activated via binding of an interleukin‐4‐induced transcription factor to a novel responsive element
1993
Ligand-activated thyroid hormone and retinoic acid receptors inhibit growth factor receptor promoter expression
1990
Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung afterin vivointratracheal plasmid-mediated gene transfer
1992
Reporter genes: Application to the study of mammalian gene transcription
1990
The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene
1989
Multiple and cooperative trans-activation domains of the human glucocorticoid receptor
1988
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors
1991 Standout
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Multiple circadian-regulated elements contribute to cycling period gene expression in Drosophila
1997
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1—Pit-1 interactions
1990
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
1993 StandoutNatureNobel
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements
1991
Multiple cell type-specific proteins differentially regulate target sequence recognition by the α retinoic acid receptor
1990
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor
1992 Standout
Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures
2013 Standout
Rate of Labelling of Mitochondrial Phosphohistidine by Radioactive Inorganic Phosphate
1964 Nature
Requirement of sulfhydryl groups for the catalytic and tRNA recognition functions of isoleucyl-tRNA synthetase
1969 StandoutNobel
PHOSPHATE BOUND TO HISTIDINE IN A PROTEIN AS AN INTERMEDIATE IN A NOVEL PHOSPHO-TRANSFERASE SYSTEM
1964
Iodohistidine as a possible intermediate in oxidative phosphorylation: Its identification and activity
1964
The topography of the purple membrane
1979 StandoutNatureNobel
Response of an unidentified phosphate fraction and of bound phosphohistidine in mitochondria to Ca++, uncouplers, and inhibitors
1964 Nobel
Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter
1998 StandoutScienceNobel
Protein Denaturation during Heat Shock and Related Stress
1989
Mapping of a retinoic acid-responsive element in the promoter region of the complement factor H gene
1990
Respiration-dependent formation of acid-stable and acid-labile forms of mitochondrial phosphoproteins and their possible interconversion
1963
A conserved tripeptide sorts proteins to peroxisomes.
1989
Determinants of target gene specificity for steroid/thyroid hormone receptors
1989
A search for conformational change on ligand binding in a human γM macroglobulin—I
1971
Extinction of the HPV18 upstream regulatory region in cervical carcinoma cells after fusion with non-tumorigenic human keratinocytes under non-selective conditions.
1991 StandoutNobel
Green Fluorescent Protein as a Marker for Gene Expression
1994 StandoutScienceNobel
BIOLUMINESCENCE AND CHEMILUMINESCENCE
1976
Quality Control by DNA Repair
1999 StandoutScienceNobel
Direct Gene Transfer into Mouse Muscle in Vivo
1990 StandoutScience
Contingent Genetic Regulatory Events in T Lymphocyte Activation
1989 Science
The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy
1993
Characteristics of an Orthophosphate Oxygen Exchange Catalyzed by Myosin, Actomyosin, and Muscle Fibers
1963 StandoutNobel
Development and Applications of Bioluminescent and Chemiluminescent Reporters and Biosensors
2019
The Formation of Bound Phosphohistidine from Adenosine Triphosphate-P32 in Mitochondria
1963 StandoutNobel
Rate and Extent of Labelling of Bound Phosphohistidine as Related to its Role in Mitochondria
1964 StandoutNatureNobel
Template-Directed Synthesis with Adenosine-5′-phosphorimidazolide
1968 StandoutScienceNobel
Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding
1982 StandoutNatureNobel
Hydrogen Exchange in Proteins as a Measure of Solvent Exclusion due to Ligands
1969 StandoutNobel
Activation of transcription by v-myb: evidence for two different mechanisms.
1989
Independent Photoreceptive Circadian Clocks Throughout Drosophila
1997 StandoutScienceNobel
Source of oxygen in the CO 2 produced in the bioluminescent oxidation of firefly luciferin
1977 StandoutNobel
32P-Labeling of Mitochondrial Protein and Lipid Fractions and Their Relation to Oxidative Phosphorylation
1966 StandoutNobel
Phosphohistidine
1963 StandoutScienceNobel
Targeting the Receptor-G q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy
1998 StandoutScienceNobel
Synthesis of polyphosphate by rat liver mitochondria
1963
Firefly Luciferase Gene: Structure and Expression in Mammalian Cells
1987
The Preparation and Characterization of 1-Phosphohistidine and 3-Phosphohistidine*
1966 StandoutNobel
The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer.
1990
TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins.
1991
Applications of bioluminescence in biotechnology and beyond
2021
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
Isoleucyl Transfer Ribonucleic Acid Synthetase Is a Single Polypeptide Chain
1970 StandoutNobel
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
1996 StandoutScienceNobel
Diversity of hepatitis B virus X gene-related transcripts in hepatocellular carcinoma: a novel polyadenylation site on viral DNA
1991
Conserved cysteine and histidine residues in the structures of the tyrosyl and methionyl‐tRNA synthetases
1982 StandoutNobel
Viruses in Human Cancers
1991 StandoutScienceNobel
POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter.
1991
Regulated expression of foreign genes in mammalian cells under the control of coliphage T3 RNA polymerase and lac repressor.
1989
Ligand-induced Resistance of Staphylococcal Nuclease and Nuclease-T to Proteolysis by Subtilisin, α-Chymotrypsin, and Thermolysin
1969 StandoutNobel
A Myc-Associated Zinc Finger Protein Binding Site Is One of Four Important Functional Regions in the CD4 Promoter
1995
Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein
1993 StandoutScience
Gq- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation.
1994
The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity.
1990
Crystallographic structure studies of an IgG molecule and an Fc fragment
1976 StandoutNatureNobel
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
1992 Standout
The RNA Component of Human Telomerase
1995 StandoutScienceNobel
Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene
1987
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
Characteristics of Bound Phosphohistidine Labeling in Mitochondria
1965 StandoutNobel
Suppression of hydrogen exchange in staphylococcal nuclease by ligands.
1968 StandoutNobel
Metabolic function of phosphohistidine
1964
Detection of phosphohistidine in nucleoside diphosphokinase isolated from Jerusalem artichoke mitochondria
1965
p48 Activates a UV-Damaged-DNA Binding Factor and Is Defective in Xeroderma Pigmentosum Group E Cells That Lack Binding Activity
1998
Two closely linked but separable promoters for human neuronal nitric oxide synthase gene transcription.
1995 StandoutNobel
The association of readily-soluble bound phosphohistidine from mitochondria with succinate thiokinase
1964 StandoutNobel
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Cationic liposome-mediated RNA transfection.
1989
Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1.
1992 StandoutNobel
Comparison of protein structure in the crystal and in solution. III. Tritium-hydrogen exchange of lysozyme and a lysozyme-saccharide complex
1968
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
The pas8 mutant of Pichia pastoris exhibits the peroxisomal protein import deficiencies of Zellweger syndrome cells--the PAS8 protein binds to the COOH-terminal tripeptide peroxisomal targeting signal, and is a member of the TPR protein family [published erratum appears in J Cell Biol 1993 Sep;122(5):following 1143]
1993
Chemical studies on methionyl-tRNA synthetase from Escherichia coli
1970
Relationships of Ca++ to “Protein-bound” Phosphate Fractions of Mitochondria
1965 StandoutNobel
Works of M. DeLuca being referenced
THE ISOLATION AND IDENTIFICATION OF PHOSPHOHISTIDINE FROM MITOCHONDRIAL PROTEIN.
1963
Immobilization of firefly luciferase on glass rods: Properties of the immobilized enzyme
1977
Detection of a Possible Intermediate in Oxidative Phosphorylation
1961 StandoutNatureNobel
Firefly luciferase gene: structure and expression in mammalian cells.
1987 Standout
Requirement of different sulfhydryl groups in the activation and transfer reactions of isoleucyl transfer ribonucleic acid synthetase
1969
Biochemical and morphological changes accompanying light organ development in the firefly, Photuris pennsylvanica
1979
Bound Phosphohistidine as an Intermediate in a Phosphorylation Reaction of Oxidative Phosphorylation Catalyzed by Mitochondrial Extracts
1963 StandoutNobel
Conformational changes of luciferase during catalyses tritium-hydrogen exchange and optical rotation studies
1967
Molecular Uniformity in Biological Catalyses
1967 Science
Two kinetically distinguishable ATP sites in firefly luciferase
1984
Source of oxygen in the CO2 produced during chemiluminescence of firefly luciferyl-adenylate and Renilla luciferin
1976
Synthesis of active firefly luciferase by in vitro translation of RNA obtained from adult lanterns
1984
The sulfhydryl groups of tryptophan-transfer ribonucleic acid synthetase
1966
Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli.
1985
Identification of Phosphohistidine in Digests from a Probable Intermediate of Oxidative Phosphorylation
1962 StandoutNobel
Firefly luciferase is targeted to peroxisomes in mammalian cells.
1987