Citation Impact
Citing Papers
p53: puzzle and paradigm.
1996 Standout
Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways.
2003 StandoutNobel
Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene
2004 StandoutNobel
Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer
2015 StandoutNobel
Alterations in adaptive immunity persist during long-duration spaceflight
2015
The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis
2009 Standout
Induction of the growth inhibitor IGF-binding protein 3 by p53
1995 Nature
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
1997 Standout
Acromegaly
2006 Standout
Activators and target genes of Rel/NF-κB transcription factors
1999 Standout
β-Arrestin Is Crucial for Ubiquitination and Down-regulation of the Insulin-like Growth Factor-1 Receptor by Acting as Adaptor for the MDM2 E3 Ligase
2005 StandoutNobel
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 Standout
Multiple proteins bind the insulin response element in the human IGFBP-1 promoter
1995
Microgravity and immune responsiveness
2002
A Human Gene Encoding a Putative Basic Helix–Loop–Helix Phosphoprotein Whose mRNA Increases Rapidly in Cycloheximide-Treated Blood Mononuclear Cells
1994
Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways
2001 StandoutNobel
Effect of Solar Particle Event Radiation and Hindlimb Suspension on Gastrointestinal Tract Bacterial Translocation and Immune Activation
2012 StandoutNobel
Cellular survival: a play in three Akts
1999 Standout
The von Hippel-Lindau Gene, Kidney Cancer, and Oxygen Sensing
2003 StandoutNobel
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
1998 StandoutNobel
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Phosphorylation of Serine 256 by Protein Kinase B Disrupts Transactivation by FKHR and Mediates Effects of Insulin on Insulin-like Growth Factor-binding Protein-1 Promoter Activity through a Conserved Insulin Response Sequence
1999
Clusterin Is a Secreted Marker for a Hypoxia-Inducible Factor-Independent Function of the von Hippel-Lindau Tumor Suppressor Protein
2006 StandoutNobel
Mechanisms involved in the side effects of glucocorticoids
2002 Standout
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
2004 Standout
Broad-Spectrum Antibiotic or G-CSF as Potential Countermeasures for Impaired Control of Bacterial Infection Associated with an SPE Exposure during Spaceflight
2015 StandoutNobel
Cloning of the Rat Insulin-Like Growth Factor-Binding Protein-2 Gene and Identification of a Functional Promoter Lacking a TATA Box
1990
Protein Kinase B/Akt Mediates Effects of Insulin on Hepatic Insulin-like Growth Factor-binding Protein-1 Gene Expression through a Conserved Insulin Response Sequence
1998
Estradiol and Antiestrogens Regulate a Growth Inhibitory Insulin-like Growth Factor Binding Protein 3 Autocrine Loop in Human Breast Cancer Cells
1996
Plants in space
2002
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
2006 StandoutNobel
Genomic and Functional Characterization of Enterococcus faecalis Isolates Recovered From the International Space Station and Their Potential for Pathogenicity
2021 StandoutNobel
Acne vulgaris
2011 Standout
Effect of Solar Particle Event Radiation on Gastrointestinal Tract Bacterial Translocation and Immune Activation
2011 StandoutNobel
Global aetiology and epidemiology of type 2 diabetes mellitus and its complications
2017 Standout
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
2010 Standout
What is the role of circulating IGF-I?
2001
Hindlimb Suspension and SPE-Like Radiation Impairs Clearance of Bacterial Infections
2014 StandoutNobel
Insulin, Insulin-Like Growth Factors and Colon Cancer: A Review of the Evidence
2001
Insulin-like Growth Factor Binding Proteins
1993
Nutrition, hormones, and breast cancer: Is insulin the missing link?
1996
Live or let die: the cell's response to p53
2002 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Considerations for non-invasive in-flight monitoring of astronaut immune status with potential use of MEMS and NEMS devices
2006
Immune System Dysregulation Occurs During Short Duration Spaceflight On Board the Space Shuttle
2012
A cytoprotective perspective on longevity regulation
2013 StandoutNobel
Genetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans
2004 StandoutNobel
HNF1, a homeoprotein member of the hepatic transcription regulatory network
1992
Spaceflight effects on T lymphocyte distribution, function and gene expression
2008
The Insulin-Like Growth Factors
1993
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain
1998 StandoutNobel
Gender difference in adrenal sensitivity to ACTH is abolished in type 2 diabetes
2015
A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial
2007
Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation
2005
Regulation of gene expression by insulin
1991
Synthesis and Function of 3-Phosphorylated Inositol Lipids
2001 Standout
Glucocorticoids and insulin regulate expression of the human gene for insulin-like growth factor-binding protein-1 through proximal promoter elements.
1994
Hepatic Nuclear Factor 3- and Hormone-Regulated Expression of the Phosphoenolpyruvate Carboxykinase and Insulin-Like Growth Factor-Binding Protein 1 Genes
1995
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
2016 Standout
Systemic Complications of Acromegaly: Epidemiology, Pathogenesis, and Management
2004 Standout
Functional analysis of glucocorticoid and insulin response sequences in the rat insulin-like growth factor-binding protein-1 promoter.
1994
Diabetes and Cancer
2010 Standout
Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study
1998 StandoutScience
International Union of Pharmacology. XXIII. The Angiotensin II Receptors
2000 Standout
Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis*
1997 Standout
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
2004 StandoutNobel
Transcriptional control of human p53-regulated genes
2008 Standout
An analysis of vertebrate mRNA sequences: intimations of translational control.
1991 Standout
Body size and composition and colon cancer risk in women
2005
Regulation of IGF binding protein-1 in Hep G2 cells by cytokines and reactive oxygen species
1999
Controls of Hair Follicle Cycling
2001 Standout
A prospective study of plasma insulin-like growth factor-1 and binding protein-3 and risk of colorectal neoplasia in women.
2000
Hepatic Nuclear Factor 3 and High Mobility Group I/Y Proteins Bind the Insulin Response Element of the Insulin-Like Growth Factor-Binding Protein-1 Promoter*
1997
The Timing of Normal Puberty and the Age Limits of Sexual Precocity: Variations around the World, Secular Trends, and Changes after Migration
2003 Standout
Correlation between FOXO1a (FKHR) and FOXO3a (FKHRL1) Binding and the Inhibition of Basal Glucose-6-Phosphatase Catalytic Subunit Gene Transcription by Insulin
2006
Nature’s hierarchical materials
2007 Standout
Risk of Crew Adverse Health Event Due to Altered Immune Response
2015
Energy balance, body composition, and puberty in children and adolescents: importance of ethnicity
2003
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor beta2-induced growth inhibition in human breast cancer cells.
1996
FKHR Binds the Insulin Response Element in the Insulin-Like Growth Factor Binding Protein-1 Promoter*
1999
Could spaceflight-associated immune system weakening preclude the expansion of human presence beyond Earth’s orbit?
2009
Works of M. Cubbage being referenced
T cell activation responses are differentially regulated during clinorotation and in spaceflight
1999
Insulin-like growth factor binding protein-3. Organization of the human chromosomal gene and demonstration of promoter activity.
1990
Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1.
1991
The promoter of the human gene for insulin-like growth factor binding protein-1. Basal promoter activity in HEP G2 cells depends upon liver factor B1.
1990