M. Cassidy

Designed protein logic to target cells with precise combinations of surface antigens

Nmd3 is a structural mimic of eIF 5A, and activates the cp GTP ase Lsg1 during 60S ribosome biogenesis

Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function

High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays

Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome

Top-down venomics of the East African green mamba, Dendroaspis angusticeps , and the black mamba, Dendroaspis polylepis , highlight the complexity of their toxin arsenals

Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases

Snakebite envenoming

Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure

Design of biologically active binary protein 2D materials

Design and synthesis of N-substituted-2-hydroxyiminoacetamides and interactions with cholinesterases

Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase

Wheat germ cell-free translation, purification, and assembly of a functional human stearoyl-CoA desaturase complex

Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability

Conjugates of salicylaldoximes and peripheral site ligands: Novel efficient nonquaternary reactivators for nerve agent-inhibited acetylcholinesterase

Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration

Improving Protein Expression, Stability, and Function with ProteinMPNN

Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase

Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers

Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade

Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies

Reactive Oxygen Species (ROS)-Based Nanomedicine

Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase

sdAb-DB: The Single Domain Antibody Database

Small-scale, semi-automated purification of eukaryotic proteins for structure determination

Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies

Structural genomics for drug design against the pathogen Coxiella burnetii

Structures of Human Acetylcholinesterase in Complex with Pharmacologically Important Ligands

Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface