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Citing Papers
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
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Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans
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Evidence from in vitro differentiating cells that adrenoceptor agonists can increase uncoupling protein mRNA level in adipocytes of adult humans: an RT-PCR study
1996
Expression of uncoupling proteins-1, -2 and -3 mRNA is induced by an adenocarcinoma-derived lipid-mobilizing factor
2002
International Union of Pharmacology nomenclature of adrenoceptors.
1994 StandoutNobel
Sex‐Dependent Dietary Obesity, Induction of UCPs, and Leptin Expression in Rat Adipose Tissues
2001
Abdominal obesity and metabolic syndrome
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Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
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The Adipose Tissue Phenotype of Hormone‐Sensitive Lipase Deficiency in Mice
2001
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
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β3 and Atypical β‐Adrenoceptors
1993
Regional differences of insulin action in adipose tissue: insights from in vivo and in vitro studies
2005
Comparison of the Release of Adipokines by Adipose Tissue, Adipose Tissue Matrix, and Adipocytes from Visceral and Subcutaneous Abdominal Adipose Tissues of Obese Humans
2004
Adipocytes as regulators of energy balance and glucose homeostasis
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Beta 3‐adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium‐derived nitric oxide in rat thoracic aorta
1999
The regulation of total body fat: lessons learned from lipectomy studies
2001
The role of a low ?1-adrenoceptor selectivity of [3H]CGP-12177 for resolving subtype-selectivity of competitive ligands
1987
Effects of the two β3-agonists, ZD7114 and ZD2079 on 24 hour energy expenditure and respiratory quotient in obese subjects
2000
Opposite actions of testosterone and progesterone on UCP1 mRNA expression in cultured brown adipocytes
2002
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Tissue distribution of beta 3-adrenergic receptor mRNA in man.
1993
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Brain–adipose tissue cross talk
2005
Coexistence of three β-adrenoceptor subtypes in white fat cells of various mammalian species
1991
RNAi screening for fat regulatory genes with SRS microscopy
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Differential recruitment and differential regulation by physiological amines of fat cell β-1, β-2 and β-3 adrenergic receptors expressed in native fat cells and in transfected cell lines
1994
Role of the β3-Adrenergic Receptor and/or a Putative β4-Adrenergic Receptor on the Expression of Uncoupling Proteins and Peroxisome Proliferator-Activated Receptor-γ Coactivator-1
1999
Physical activity and resting metabolic rate
2003
A central role for JNK in obesity and insulin resistance
2002 StandoutNature
A Review of the Microcirculation of Adipose Tissue: Anatomic, Metabolic, and Angiogenic Perspectives
1997
Demonstration of an in vivo functional beta 3-adrenoceptor in man.
1995
Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
1999 StandoutNatureNobel
α1-Adrenergic Stimulation Potentiates the Thermogenic Action of β3-Adrenoreceptor-generated cAMP in Brown Fat Cells
1997
Norepinephrine Is Required for Leptin Effects on Gene Expression in Brown and White Adipose Tissue1
1999
Expression of uncoupling protein in skeletal muscle and white fat of obese mice treated with thermogenic beta 3-adrenergic agonist.
1996
The Negative Inotropic Effect of β3-Adrenoceptor Stimulation in the Beating Guinea Pig Heart
2000
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Review article: Is obesity an inflammatory illness? Role of low‐grade inflammation and macrophage infiltration in human white adipose tissue
2006
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2002
Genetically lean mice result from targeted disruption of the RIIβ subunit of protein kinase A
1996 Nature
Adaptive thermogenesis in adipocytes: Is beige the new brown?
2013
Obesity as a medical problem
2000 StandoutNature
L 1 ‐ IMIDAZOLINE RECEPTORS: HISTORICAL PERSPECTIVE
1992
The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones
2003
Proteolytic and lipolytic responses to starvation
2006
Differential Distribution of β-Adrenergic Receptor Subtypes in Blood Vessels of Knockout Mice Lacking β1-or β2-Adrenergic Receptors
2001 StandoutNobel
The human adipose tissue is a source of multipotent stem cells
2004
Functional beta3-adrenoceptor in the human heart.
1996
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
A pathogenic role of visceral fat beta 3-adrenoceptors in obesity.
1995
Central Leptin Regulates the UCP1 and obGenes in Brown and White Adipose Tissue via Different β-Adrenoceptor Subtypes
2000
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Lipolysis: pathway under construction
2005
Stimulation of the Extracellular Signal-Regulated Kinase 1/2 Pathway by HumanBeta-3 Adrenergic Receptor: New Pharmacological Profile and Mechanism of Activation
1999
Selective activation of brown adipocyte hormone-sensitive lipase and cAMP production in the mouse by β3-adrenoceptor agonists
1995
G protein—coupled receptor kinases
1993 StandoutNobel
Targeted Disruption of the β3-Adrenergic Receptor Gene
1995
Up‐regulation of uncoupling proteins by β‐adrenergic stimulation in L6 myotubes
2001
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Identification of the platelet ADP receptor targeted by antithrombotic drugs
2001 StandoutNatureNobel
Developmental Origin of Fat: Tracking Obesity to Its Source
2007
Comparison of Hormone-Sensitive Lipase Activity in Visceral and Subcutaneous Human Adipose Tissue1
1997
Molecular mechanisms involved in α-adrenergic responses
1981
Innervation of mammalian white adipose tissue: implications for the regulation of total body fat
1998
Brown Adipose Tissue in Adult Humans: A Metabolic Renaissance
2013
Influence of sodium on the alpha 2-adrenergic receptor system of human platelets. Role for intraplatelet sodium in receptor binding.
1983
Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors
2008 StandoutNobel
βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance
2002 StandoutScienceNobel
Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults
2011 Standout
Mechanisms of the antidiabetic effects of the β3-adrenergic agonist CL-316243 in obese Zucker-ZDF rats
1998
Extreme Insulin Resistance of the Central Adipose Depot In Vivo
2002
Uncoupling protein-1: involvement in a novel pathway for β-adrenergic, cAMP-mediated intestinal relaxation
2002
Downregulation of myocardial beta-adrenergic receptors. Receptor subtype selectivity.
1994
β3-Adrenergic agonist induces a functionally active uncoupling protein in fat and slow-twitch muscle fibers
1998
Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.
1988 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
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Myocyte Adrenoceptor Signaling Pathways
2003 StandoutScienceNobel
A Transgenic Model of Visceral Obesity and the Metabolic Syndrome
2001 StandoutScience
Free Fatty Acids Are Independently Associated with All-Cause and Cardiovascular Mortality in Subjects with Coronary Artery Disease
2006
β-Adrenergic regulation of lipolysis and blood flow in human skeletal muscle in vivo
1998
Heterogeneity of alpha-2 adrenergic receptors
1985
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Regional variation in adipose tissue metabolism of severely obese premenopausal women.
1995
Biological Action of Leptin as an Angiogenic Factor
1998 StandoutScience
Role of β1- and β3-adrenoceptors in the regulation of lipolysis and thermogenesis in rat brown adipocytes
1997
Pharmacological Characterizations of Adrenergic Receptors in Human Adipocytes
1981 StandoutNobel
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.
1996 StandoutNobel
β1 to β3 Switch in Control of Cyclic Adenosine Monophosphate during Brown Adipocyte Development Explains Distinct β-Adrenoceptor Subtype Mediation of Proliferation and Differentiation1
1999
Phosphodiesterase 4D is required for β 2 adrenoceptor subtype-specific signaling in cardiac myocytes
2005 StandoutNobel
Subcutaneous and Visceral Adipose Tissue: Their Relation to the Metabolic Syndrome
2000 Standout
β-Arrestin 1 down-regulation after insulin treatment is associated with supersensitization of β2 adrenergic receptor Gαs signaling in 3T3-L1 adipocytes
2002
Alterations in dynamic heart rate control in the β1-adrenergic receptor knockout mouse
1998 StandoutNobel
Sites and cellular mechanisms of human adrenergic thermogenesis–a review
2002
Metabolic reprogramming and cancer progression
2020 StandoutScience
The β-adrenergic radioligand [3H]CGP-12177, generally classified as an antagonist, is a thermogenic agonist in brown adipose tissue
1989
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
2011 Standout
Allosteric activation of the CaR by l -amino acids
2000 StandoutNobel
Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α 2 -Adrenergic Receptor
1987 StandoutScienceNobel
The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation
2001
Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase
2004 StandoutScience
Augmentation of Cardiac Contractility Mediated by the Human β 3 -Adrenergic Receptor Overexpressed in the Hearts of Transgenic Mice
2001 StandoutNobel
beta1-adrenergic receptors mediate beta3-adrenergic-independent effects of CGP 12177 in brown adipose tissue.
2000
STRUCTURE AND FUNCTION OF THE β3-ADRENERGIC RECEPTOR
1997
Coexisting beta-adrenoceptor subtypes: significance for thermogenic process in brown fat cells
1994
p38 Mitogen-Activated Protein Kinase Is the Central Regulator of Cyclic AMP-Dependent Transcription of the Brown Fat Uncoupling Protein 1 Gene
2004
Appropriate Physical Activity Intervention Strategies for Weight Loss and Prevention of Weight Regain for Adults
2009 Standout
The PDZ-binding motif of the β 2 -adrenoceptor is essential for physiologic signaling and trafficking in cardiac myocytes
2003 StandoutNobel
Improved Glucose and Lipid Metabolism in Genetically Obese Mice Lacking aP2
2000
INSIGHTS FROM IN VIVO MODIFICATION OF ADRENERGIC RECEPTOR GENE EXPRESSION
1998 StandoutNobel
The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP
2000
Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.
1988 StandoutNobel
The putative β4-adrenergic receptor is a novel state of the β1-adrenergic receptor
2001
Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism.
1992 StandoutNobel
What Is the Role of β-Adrenergic Signaling in Heart Failure?
2003
ADP Receptors on Platelets
1996
Differential regulation of the expression of α1-adrenergic receptor subtype genes in brown adipose tissue
1997
Apparent absence of alpha-2 adrenergic receptors from hamster brown adipocytes
1982
Works of M Berlan being referenced
Effect of a 7‐day treatment with idazoxan and its 2‐methoxy derivative RX 821001 on α2‐adrenoceptors and non‐adrenoceptor idazoxan binding sites in rabbits
1991
Human fat cell beta-adrenergic receptors: beta-agonist-dependent lipolytic responses and characterization of beta-adrenergic binding sites on human fat cell membranes with highly selective beta 1-antagonists.
1988
A reliable assay for beta-adrenoceptors in intact isolated human fat cells with a hydrophilic radioligand, [3H]CGP-12177.
1988
Mechanism of lipolytic action of a new alpha-2 adrenergic antagonist of the piperazinopyrimidine family: RP 55462.
1989
Beta 3-adrenoceptors in dog adipose tissue: studies on their involvement in the lipomobilizing effect of catecholamines.
1993
Human fat cell alpha-2 adrenoceptors. I. Functional exploration and pharmacological definition with selected alpha-2 agonists and antagonists.
1989
Beta3‐adrenoceptors in the cardiovascular system
1995
Adrenergic regulation of adipocyte metabolism
1997
Effects of physiological and pharmacological variation of sympathetic nervous system activity on plasma non‐esterified fatty acid concentrations in man.
1993
Identification of human platelet a2‐adrenoceptors with a new antagonist [3H]‐RX821002, a 2‐methoxy derivative of idazoxan
1990
Dynamic strength training improves insulin sensitivity and functional balance between adrenergic alpha 2A and beta pathways in subcutaneous adipose tissue of obese subjects
2005
Atrial natriuretic peptide stimulates lipid mobilization during repeated bouts of endurance exercise
2005
Culture of Human Adipose Tissue Explants Leads to Profound Alteration of Adipocyte Gene Expression
2003
Control of lipolysis by natriuretic peptides and cyclic GMP
2008
Involvement of a cGMP-dependent Pathway in the Natriuretic Peptide-mediated Hormone-sensitive Lipase Phosphorylation in Human Adipocytes
2003
Uncoupling Protein-2 Messenger Ribonucleic Acid Expression During Very-Low-Calorie Diet in Obese Premenopausal Women
1998
Peripheral cardiovascular actions of SR 58611 A, a beta 3‐adrenoceptor agonist, in the dog: lack of central effect
1999
Metabolic response to various β‐adrenoceptor agonists in β3‐adrenoceptor knockout mice: Evidence for a new β‐adrenergic receptor in brown adipose tissue
1998
Fat Cell α2-Adrenoceptors: The Regulation of Fat CellFunction and Lipolysis*
1995
Differential activation of β1‐, β2‐ and β3‐adrenoceptors by catecholamines in white and brown adipocytes
1995
Recent developments on lipolysis regulation in humans and discovery of a new lipolytic pathway
2000
In situ assessment of the role of the β1, β2‐ and β3‐adrenoceptors in the control of lipolysis and nutritive blood flow in human subcutaneous adipose tissue
1996
Increased lipolysis in adipose tissue and lipid mobilization to natriuretic peptides during low-calorie diet in obese women
2002
Physiological regulation of NEFA availability: lipolysis pathway
2004
Do regional differences in adipocyte biology provide new pathophysiological insights?
2003
Exercise-induced lipid mobilization in subcutaneous adipose tissue is mainly related to natriuretic peptides in overweight men
2008
Lipid Mobilization with Physiological Atrial Natriuretic Peptide Concentrations in Humans
2005
Lipolytic effects of conventional β3‐adrenoceptor agonists and of CGP 12,177 in rat and human fat cells: preliminary pharmacological evidence for a putative β4‐adrenoceptor
1997
Adrenergic Receptors and Fat Cells: Differential Recruitment by Physiological Amines and Homologous Regulation
1995
Lack of desensitization of alpha-2-mediated inhibition of lipolysis in fat cells after acute and chronic treatment with clonidine.
1985
The positive chronotropic effect induced by BRL 37344 and CGP 12177, two beta-3 adrenergic agonists, does not involve cardiac beta adrenoceptors but baroreflex mechanisms.
1992
Differential regulation of fat cell beta-2 and beta-1 adrenoceptors by endogenous catecholamines in dog.
1989
Discrepancy in the regulatory effects of sodium and guanine nucleotides on adrenaline and clonidine binding to α2-adrenoceptors in human fat cell membranes
1981
Expression of beta3-adrenoceptors with low lipolytic action in human subcutaneous white adipocytes.
1996
Beta-3 adrenoceptor-mediated increase in cutaneous blood flow in the dog.
1994
Natriuretic peptides: a new lipolytic pathway in human adipocytes
2000
Control of lipolysis in intra-abdominal fat cells of nonhuman primates: comparison with humans.
1995
Characterization of physiological agonist selectivity of human fat cell α2-adrenoceptors: Adrenaline is the major stimulant of the α2-adrenoceptors
1982
Natriuretic peptide-dependent lipolysis in fat cells is a primate specificity
2002
Evidence for the α2 nature of the α-adrenergic receptor inhibiting lipolysis in human fat cells
1980
Evidence for numerous brown adipocytes lacking functional beta 3-adrenoceptors in fat pads from nonhuman primates.
1996
Identification of α2-adrenergic receptors in human fat cell membranes by [3H]chlonidine binding
1980
Characterization of dog fat cell adrenoceptors: variations in alpha-2 and beta adrenergic receptors distribution according to the extent of the fat deposits and the anatomical location.
1987
Atrial Natriuretic Peptide Induces Postprandial Lipid Oxidation in Humans
2008
Heterogeneous distribution of beta and alpha‐2 adrenoceptor binding sites in human fat cells from various fat deposits: functional consequences
1987
Alpha‐adrenergic antilipolytic effect of adrenaline in human fat cells of the thigh: comparison with adrenaline responsiveness of different fat deposits
1979
Dynamic Strength Training Improves Insulin Sensitivity without Altering Plasma Levels and Gene Expression of Adipokines in Subcutaneous Adipose Tissue in Obese Men
2006
Adipose Tissue Lipolysis and Hormone-Sensitive Lipase Expression during Very-Low-Calorie Diet in Obese Female Identical Twins1
1997
On the presence of a putative fourth β-adrenoceptor in human adipose tissue
1998
Catecholamine effects on lipolysis and blood flow in human abdominal and femoral adipose tissue
1998
Fat cell adrenergic receptors and the control of white and brown fat cell function
1993
Atrial natriuretic peptide contributes to the physiological control of lipid mobilization in humans
2004
A postsynaptic α, 2-receptor: The alpha-adrenergic receptor of hamster white fat cells
1980
Obesity modifies the adrenergic status of dog adipose tissue.
1989